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1 Human lung epithelial cell cultures for analysis of inhaled toxicants: Lessons learned and future directions
article 2018    
Author: Hiemstra, P.S. · Grootaers, G.G. · Does, A.M. van der · Krul, C.A.M. · Kooter, I.M.
Keywords: Health · Inhalation toxicology · Air-liquid interface · Epithelial cells · Airway; Lung · Cell culture · Healthy for Life · Healthy Living · Life Urban Mobility & Environment · RAPID - Risk Analysis for Products in Development EMS - Environmental Modelling, Sensing & Analysis · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

2 Extracellular matrix components and regulators in the airway smooth muscle in asthma
article 2008    
Author: Araujo, B.B. · Dolhnikoff, M. · Silva, L.F.F. · Elliot, J. · Lindeman, J.H.N. · Ferreira, D.S. · Mulder, A. · Gomes, H.A.P. · Fernezlian, S.M. · James, A. · Mauad, T.
Keywords: Airway smooth muscle · Extracellular matrix · Fatal asthma · Metalloproteinases · Remodelling · Tissue inhibitor of metalloproteinase · Adolescent · Adult · Asthma · Bronchi · Case-Control Studies · Extracellular Matrix · Female · Humans · Male · Matrix Metalloproteinases · Middle Aged · Muscle, Smooth · Tissue Inhibitor of Metalloproteinases
[Abstract]

3 Cellular response of mucociliary differentiated primary bronchial epithelial cells to diesel exhaust
article 2016    
Author: Zarcone, M.C. · Duistermaat, E. · Schadewijk, A. van · Jedynksa, A.D. · Hiemstra, P.S. · Kooter, I.M.
Keywords: Health · Airway epithelial cells · Air liquid interface · Diesel exhaust · Oxidative stress · Inflammation · Healthy for Life · Healthy Living · Life Urban Mobility & Environment · RAPID - Risk Analysis for Products in Development EMS - Environmental Modelling, Sensing & Analysis · ELSS - Earth, Life and Social Sciences
[Abstract]

4 Diesel exhaust alters the response of cultured primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD) to non-typeable Haemophilus influenzae
article 2017    
Author: Zarcone, M.C. · Schadewijk, A. van · Duistermaat, E. · Hiemstra, P.S. · Kooter, I.M.
Keywords: Health · Air pollution · Airway epithelial cells · Antimicrobial peptides · Antimicrobial response · COPD · Diesel exhaust · Integrated stress response · Non-typeable Haemophilus influenzae · Environment & Sustainability · Urbanisation · Urban Mobility & Environment · EMS - Environmental Modelling, Sensing & Analysis · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

5 Cellular effects in an in vitro human 3D cellular airway model and A549/BEAS-2B in vitro cell cuultures following air exposure to cerium oxide particles at an air-liquid interface
article 2016    
Author: Kooter, I.M. · Grollers-Mulderij, M. · Steenhof, M. · Duistermaat, E. · Acker, F.A.A. van · Staal, Y.C.M. · Tromp, P.C. · Schoen, E.D. · Kuiper, C.F. · Someren, E.P. van
Keywords: Health · A549 · Air-liquid interface · BEAS-2B · Cerium oxide · Human epithelial airway model · Nanoparticles · Healthy for Life · Healthy Living · Urban Mobility & Environment · Environmental Modelling, Sensing & Analysis · ELSS - Earth, Life and Social Sciences
[Abstract]

6 Feasibility of a 3D human airway epithelial model to study respiratory absorption
article 2014    
Author: Reus, A.A. · Maas, W.J.M. · Jansen, H.T. · Constant, S. · Staal, Y.C.M. · Triel, J.J. van · Kuper, C.F.
Keywords: Biology · Respiratory absorption · 3D human airway model · Biomedical Innovation · Healthy Living · Life Triskelion BV · TARA - Toxicology and Risk Assessment PHS - Pharmacokinetics & Human Studies (tot 2013 daarna KFP) · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

7 Respiratory allergy and pulmonary irritation to trimellitic anhydride in Brown Norway rats
article 2003    
Author: Arts, J.H.E. · Bloksma, N. · Leusink-Muis, T. · Kuper, C.F.
Keywords: Biology Nutrition · Toxicology and Applied Pharmacology · Airway irritation · Brown Norway rats · Nonspecific airway hyperresponsiveness · Respiratory allergy · Trimellitic anhydride · acetylglucosaminidase · immunoglobulin E · irritant agent · lactate dehydrogenase · methacholine · protein · trimellitic anhydride · animal experiment · animal tissue · article · female · histopathology · immunoglobulin blood level · leukocyte · lung injury · lung lavage · nonhuman · occupational asthma · rat · respiratory tract allergy · sensitization · Allergens · Animals · Body Weight · Bronchoalveolar Lavage Fluid · Female · Immunization · Immunoglobulin E · Lung · Organ Size · Phthalic Anhydrides · Rats · Rats, Inbred BN · Respiration · Respiratory Function Tests · Rattus norvegicus
[Abstract]

8 Approaches to induce and elicit respiratory allergy: Impact of route and intensity of exposure
article 2003    
Author: Arts, J.H.E. · Kuper, C.F.
Keywords: Toxicology Health · Toxicology and Applied Pharmacology · Airway irritation · Respiratory allergy · Route and intensity of exposure · allergen · irritant agent · allergic reaction · biosafety · conference paper · environmental factor · exposure · heredity · human · inhalation test · nonhuman · prediction · priority journal · respiratory tract allergy · risk assessment · risk management · sensitization · standardization · Administration, Cutaneous · Administration, Inhalation · Allergens · Animals · Dose-Response Relationship, Drug · Predictive Value of Tests · Respiratory System · Animalia
[Abstract]

9 A practical approach to assess inhalation toxicity of metal oxide nanoparticles in vitro
article 2018    
Author: Dankers, A.C.A. · Kuper, C.F. · Boumeester, A.J. · Fabriek, B.O. · Kooter, I.M. · Gröllers-Mulderij, M. · Tromp, P. · Nelissen, I. · Zondervan-Van Den Beuken, E.K. · Vandebriel, R.J.
Keywords: Toxicology · 3D human airway model · Dendritic cells · Inhalation toxicology · Metal oxides · MucilAir · Nanoparticles · Nanotoxicology · Food and Nutrition · Healthy Living · Life Urban Mobility & Environment · RAPID - Risk Analysis for Products in Development EMS - Environmental Modelling, Sensing & Analysis · ELSS - Earth, Life and Social Sciences
[Abstract]

10 Evaluation of systematic assessment of asthma-like symptoms and tobacco smoke exposure in early childhood by well-child professionals: A randomised trial
article 2014    
Author: Hafkamp-de Groen, E. · Valk, R.J.P. van der · Mohangoo, A.D. · Wouden, J.C. van der · Duijts, L. · Jaddoe, V.W. · Hofman, A. · Koning, H.J. de · Jongste, J.C. de · Raat, H.
Keywords: Health · Nitric oxide · Tobacco smoke · Airway resistance · Asthma · Child · Clinical evaluation · Controlled study · Environmental exposure · Health care personnel · Outcome assessment · Patient assessment · Patient counseling · Prevalence · Professional practice · Qality of life · Risk assessment · Wheezing · Healthy for Life · Healthy Living · Behavioural Changes · CH - Child Health · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

11 Neonatal supplementation of processed supernatant from Lactobacillus rhamnosus GG improves allergic airway inflammation in mice later in life
article 2013    
Author: Harb, H. · Tol, E.A.F. van · Heine, H. · Braaksma, M. · Gross, G. · Overkamp, K. · Hennen, M. · Alrifai, M. · Conrad, M.L. · Renz, H. · Garn, H.
Keywords: Biology · Asthma · LGG · Neonatal Animal Model · Prevention · Soluble Factors · Interleukin 10 · Probiotic Agent · Tumor Necrosis Factor Alpha · Allergic Airway Inflammation · Animal Cell · Animal Experiment · Article · Controlled Study · Cytokine Production · female · Helper Cell · Immunomodulation · In Vitro Study · In Vivo Study · Lactobacillus Rhamnosus · macrophage · Mouse · Newborn · Nonhuman · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[Abstract]

12 Influence of inspiratory resistance on performance during graded exercise tests on a cycle ergometer
article 2004    
Author: Heus, R. · Hartog, E.A. den · Kistemaker, L.J.A. · Dijk, W.J. van · Swenker, G.
Keywords: Positive pressure breathing · Exercise · Performance · Graded exercise test · Inspiratory resistance · Oxygen consumption · Time to exhaustion · Work load · Hazardous materials · Oxygen · Parameter estimation · Personnel · Breathing · Inspiratory resistance · Time to exhaustion (TTE) · Ergonomics · Airway resistance · Bicycle ergometer · Exhaustion · Expiratory flow rate · Fitness · Gas mask · Heart rate · Inspiratory capacity · Lung minute volume · Lung resistance · Manual labor · Metabolic rate · Oxygen consumption · Carbon Dioxide · Exercise Test · Oxygen Consumption · Respiratory Mechanics · Respiratory Muscles · Respiratory Protective Devices · Workload
[Abstract]

13 Airway morphology and function of rats following dermal sensitization and respiratory challenge with low molecular weight chemicals
article 1998    
Author: Arts, J.H.E. · Kuper, C.F. · Spoor, S.M. · Bloksma, N.
Keywords: Nutrition · 1 chloro 2,4 dinitrobenzene · Immunoglobulin e · Salicylic acid methyl ester · Trimellitic anhydride · Airway · Animal experiment · Animal model · Animal tissue · Asthma · Breathing rate · Controlled study · Histopathology · Immunoglobulin blood level · Larynx · Lung function test · Morphology · Nonhuman · Occupational asthma · Provocation test · Rat · Sensitization · Allergens · Animals · Body Weight · Bronchi · Dermatitis, Allergic Contact · Dinitrochlorobenzene · Female · Immunoglobulin E · Organ Size · Phthalic Anhydrides · Rats · Rats, Inbred BN · Rats, Wistar · Respiratory Function Tests · Respiratory Hypersensitivity · Salicylates
[Abstract]

14 The effect of small peer group continuous quality improvement on the clinical practice of midwives in The Netherlands
article 2003    
Author: Engels, Y. · Verheijen, N. · Fleuren, M. · Mokkink, H. · Grol, R.
Keywords: Health · Airway · Artificial membrane · Aspiration · Blood pressure measurement · Clinical practice · Controlled study · Data analysis · Health care · Human experiment · Membrane rupture · Newborn care · Normal human · Perineum · Practice guideline · Primary health care · Qualitative analysis · Quality control · Randomization · Review · Suturing method · Adult · Chi-Square Distribution · Clinical Competence · Female · Guideline Adherence · Humans · Inservice Training · Middle Aged · Midwifery · Netherlands · Nurse Midwives · Nurse's Role · Nursing Methodology Research · Outcome Assessment (Health Care) · Peer Group · Quality Assurance, Health Care · Questionnaires · Time Factors
[Abstract]

15 Alveolar macrophages suppress non-specific inflammation caused by inhalation challenge with trimellitic anhydride conjugated to albumin
article 2006    
Author: Valstar, D.L. · Schijf, M.A. · Arts, J.H.E. · Kuper, C.F. · Nijkamp, F.P. · Storm, G. · Bloksma, N. · Henricks, P.A.J.
Keywords: Health · Toxicology and Applied Pharmacology · Airway inflammation · Alveolar macrophages · Early asthmatic response · Occupational asthma · Trimellitic anhydride · albumin · clodronic acid · immunoglobulin E · liposome · trimellitic anhydride · animal experiment · animal model · animal tissue · article · controlled study · female · inflammation · inflammatory cell · inhalation · lung alveolus macrophage · lung fluid · lung function · lung lavage · lung minute volume · nonhuman · occupational asthma · occupational exposure · priority journal · rat · sensitization · tidal volume · Allergens · Animals · Asthma · Bone Density Conservation Agents · Bronchial Hyperreactivity · Bronchoalveolar Lavage Fluid · Cattle · Clodronic Acid · Cytokines · Drug Therapy, Combination · Female · Haptens · Immunoglobulin E · Liposomes · Macrophages, Alveolar · Occupational Diseases · Phthalic Anhydrides · Protein Binding · Rats · Rats, Inbred BN · Respiratory Function Tests · Serum Albumin, Bovine · Rattus norvegicus
[Abstract]

16 Alveolar macrophages have a dual role in a rat model for trimellitic anhydride-induced occupational asthma
article 2006    
Author: Valstar, D.L. · Schijf, M.A. · Nijkamp, F.P. · Storm, G. · Arts, J.H.E. · Kuper, C.F. · Bloksma, N. · Henricks, P.A.J.
Keywords: Health · Toxicology and Applied Pharmacology · Airway inflammation · Alveolar macrophages · Early asthmatic response · Occupational asthma · Trimellitic anhydride · clodronic acid · immunoglobulin E · interleukin 6 · liposome · trimellitic anhydride · tumor necrosis factor alpha · animal cell · animal experiment · animal model · animal tissue · article · body weight · cell function · controlled study · disease severity · female · immunoglobulin blood level · lung alveolus macrophage · lung function · lung injury · lung lavage · lymphocyte depletion · nonhuman · occupational asthma · organ weight · rat · respiratory tract inflammation · Allergens · Analysis of Variance · Animals · Asthma · Cytokines · Disease Models, Animal · Female · Immunoglobulin E · Lung · Macrophages, Alveolar · Occupational Diseases · Phthalic Anhydrides · Rats · Rats, Inbred BN · Respiratory Function Tests · Statistics, Nonparametric · Animalia · Rattus norvegicus
[Abstract]

17 Respiratory Allergy to Trimellitic Anhydride in Rats: Concentration-Response Relationships during Elicitation
article 2004    
Author: Arts, J.H.E. · Koning, M.W. de · Bloksma, N. · Kuper, C.F.
Keywords: Biology · Toxicology and Applied Pharmacology · drug vehicle · immunoglobulin E · methacholine · trimellitic anhydride · airway dynamics · animal experiment · animal model · animal tissue · article · breathing pattern · breathing rate · concentration response · controlled study · female · histopathology · immunoglobulin blood level · inhalation · larynx · larynx injury · lung · lung weight · nonhuman · priority journal · rat · respiratory tract allergy · skin sensitization · squamous cell metaplasia · tidal volume · trachea · Administration, Inhalation · Allergens · Animals · Body Weight · Bronchial Provocation Tests · Dose-Response Relationship, Drug · Female · Immunoglobulin E · Lung · Methacholine Chloride · No-Observed-Adverse-Effect Level · Organ Size · Phthalic Anhydrides · Rats · Rats, Inbred BN · Rats, Wistar · Respiratory Function Tests · Respiratory Hypersensitivity · Animalia · Rattus norvegicus
[Abstract]

18 Respiratory sensitization : Advances in assessing the risk of respiratory inflammation and irritation
article 2011    
Author: Vandebriel, R. · Callant Cransveld, C. · Crommelin, D. · Diamant, Z. · Glazenburg, B. · Joos, G. · Kuper, F. · Natsch, A. · Nijkamp, F. · Noteborn, H. · Pieters, R. · Roberts, D. · Roggen, E. · Rorije, E. · Seed, M. · Sewald, K. · Heuvel, R. van den · Engelen, J. van · Verstraelen, S. · Loveren, H. van
Keywords: Toxicology · ASAT · Asthma · In vitro · In vivo · Integrated testing · QSAR · Respiratory tract · Rhinitis · Risk assessment · Sensitization · contact allergen · immunoglobulin E · airway remodeling · animal testing alternative · biosafety · bronchus hyperreactivity · cell assay · cellular immunity · dendritic cell · disease predisposition · functional genomics · human · immunopathology · immunoreactivity · in vitro study · mathematical model · mucosal immunity · nonhuman · occupational asthma · predictive value · process development · process model · quantitative analysis · quantitative structure activity relation · reaction analysis · respiratory sensitization · respiratory tract inflammation · respiratory tract injury · review · risk assessment · risk factor · sensitization · Animal Testing Alternatives · Hazardous Substances · Humans · Respiratory Hypersensitivity · Respiratory Tract Diseases · Toxicity Tests · Animalia · Healthy for Life · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

19 The respiratory local lymph node assay as a tool to study respiratory sensitizers
article 2008    
Author: Arts, J.H.E. · Jong, W.H. de · Triel, J.J. van · Schijf, M.A. · Klerk, A. de · Loveren, H. van · Kuper, C.F.
Keywords: Health · Toxicology and Applied Pharmacology · Contact allergy · LLNA · Potency · Respiratory allergy · Sensitizers · 1 chloro 2,4 dinitrobenzene · allergen · formaldehyde · hexamethylene diisocyanate · isophorone · oxazolone · phthalic anhydride · salicylic acid methyl ester · trimellitic anhydride · airway · animal experiment · article · cell proliferation · concentration response · contact allergy · controlled study · histopathology · local lymph node assay · male · molecular weight · mouse · nonhuman · respiratory tract allergy · respiratory tract examination · skin sensitization · toxicity testing · Animals · Body Weight · Chromatography, High Pressure Liquid · Dose-Response Relationship, Drug · Local Lymph Node Assay · Male · Mass Spectrometry · Mice · Mice, Inbred BALB C · Organ Size · Particle Size · Respiratory System · Mus
[Abstract]

20 Dose-response relationships and threshold levels in skin and respiratory allergy
article 2006    
Author: Arts, J.H.E. · Mommers, C. · Heer, C.de
Keywords: Health · Toxicology and Applied Pharmacology · Dose-Response · Elicitation · Respiratory Allergy · Sensitization · Skin Allergy · 1 chloro 2,4 dinitrobenzene · 1 fluoro 2,4 dinitrobenzene · acid anhydride · aldehyde · benzocaine · bronopol · chlorocresol · cytokine · dichromate potassium · diethylamine · ethylene · eugenol · formaldehyde · geraniol · glutaraldehyde · immunoglobulin E antibody · isocyanic acid derivative · isoeugenol · kathon cg · linalool · methacrylic acid derivative · myristic acid isopropyl ester · nickel · oxazolone · phthalic anhydride · rubber · subtilisin · toluene diisocyanate · tuberculin · unindexed drug · airway obstruction · analytic method · antigen specificity · CD4+ T lymphocyte · clinical study · concentration (parameters) · Dermatophagoides farinae · Dermatophagoides pteronyssinus · dose response · expiratory flow · exposure · forced expiratory volume · guinea pig · human · hypersensitivity reaction · Langerhans cell · nonhuman · occupational asthma · occupational hazard · respiratory tract allergy · review · safety · sensitivity analysis · skin allergy · skin defect · skin irritation · skin sensitization · skin test · urticaria · Allergens · Animals · Dermatitis, Allergic Contact · Dose-Response Relationship, Drug · Guidelines · Humans · Molecular Weight · No-Observed-Adverse-Effect Level · Occupational Exposure · Respiratory Hypersensitivity · Risk Assessment · Skin Tests · Animalia · Cavia porcellus · Dermatophagoides farinae · Dermatophagoides pteronyssinus
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 20 found. | Sort by date