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1 C-reactive protein: A cardiovascular risk factor report on the CRP hot-topic workshop october 1, 1997
article 1998    
Author: Maat, M.P.M. de · Haverkate, F. · Kluft, C.
Keywords: Biology · Antilipemic agent · C reactive protein · Estradiol · Estrogen receptor · Pravastatin · Acute phase response · Agina pectoris · Animal model · Atherosclerosis · Cardiovascular disease · Chlamydophila pneumoniae · Controlled study · Coronary artery disease · Disease association · Estrogen therapy · Human · Hyperlipidemia · Inflammation · Nonhuman · Rrisk factor
[Abstract]

2 Effects of gemfibrozil and ciprofibrate on plasma levels of tissue-type plasminogen activator, plasminogen activator inhibitor-1 and fibrinogen in hyperlipidaemic patients
article 1997    
Author: Kockx, M. · Maat, M.P.M. de · Knipscheer, H.C. · Kastelein, J.P. · Kluft, C. · Princen, H.M.G. · Kooistra, T.
Keywords: Biology · Antigen · Antilipemic agent · Cholesterol · Ciprofibrate · Fibrinogen · Gemfibrozil · Plasminogen activator inhibitor · Tissue plasminogen activator · Triacylglycerol · Adult · Blood level · Cholesterol blood level · Clinical trial · Controlled clinical trial · Controlled study · Double blind procedure · Drug effect · Enzyme immunoassay · Female · Fibrinogen blood level · Hyperlipidemia · Major clinical study · Male · Priority journal · Triacylglycerol blood level · Aged · Antilipemic Agents · Cholesterol · Clofibric Acid · Double-Blind Method · Female · Fibrinogen · Gemfibrozil · Humans · Hyperlipoproteinemia Type II · Male · Middle Aged · Plasminogen Activator Inhibitor 1 · Smoking · Tissue Plasminogen Activator · Treatment Outcome
[Abstract]

3 Cholestrol content of the rat lens is lowered by administration of simvastatin, but not pravastatin
article 1993    
Author: Vries, A.C.J. de · Vermeer, M.A. · Bredman, J.J. · Bar, P.R. · Cohen, L.H.
Keywords: Pharmacology · 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors · hypocholesterolaemic drugs · antilipemic agent · drug derivative · hydroxymethylglutaryl coenzyme A reductase inhibitor · hypocholesterolemic agent · mevinolin · animal experiment · cholesterol metabolism · oral drug administration · biosynthesis · dose response · drug effect · enzymology · liver microsome · metabolism · organ culture · rat strain · time · Aging · Animal · Anticholesteremic Agents · Antilipemic Agents · Cholesterol · Dose-Response Relationship, Drug · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lens, Crystalline · Lovastatin · Microsomes, Liver · Organ Culture · Pravastatin · Rats · Rats, Wistar · Simvastatin · Time Factors
[Abstract]

4 Studies on the mechanism of fibrate-inhibited expression of plasminogen activator inhibitor-1 in cultured hepatocytes from cynomolgus monkey
article 1997    
Author: Arts, J. · Kooistra, T.
Keywords: Biology · 9-cis retinoic acid · fibrates · hepatocytes · peroxisome proliferator-activated receptor · plasminogen activator inhibitor-1 · 2 [1 (3 amidinothiopropyl) 1h indol 3 yl] 3 (1 methyl 1h indol 3 yl)maleimide · alitretinoin · antilipemic agent · epidermal growth factor · fibric acid derivative · gemfibrozil · peroxisome proliferator · phorbol 13 acetate 12 myristate · plasminogen activator inhibitor 1 · protein kinase C · protein kinase C inhibitor · retinoid X receptor · transforming growth factor beta · animal cell · controlled study · dose time effect relation · drug mechanism · enzyme activity · gene expression · hyperlipidemia · liver cell culture · monkey · nonhuman · Animals · Antilipemic Agents · Cells, Cultured · Dose-Response Relationship, Drug · Liver · Macaca fascicularis · Plasminogen Activator Inhibitor 1 · RNA, Messenger
[Abstract]

5 Caloric restriction and exercise increase plasma ANGPTL4 levels in humans via elevated free fatty acids
article 2009    
Author: Kersten, S. · Lichtenstein, L. · Steenbergen, E. · Mudde, K. · Hendriks, H.F.J. · Hesselink, M.K. · Schrauwen, P. · Müller, M.
Keywords: Nutrition · Biomedical Research · ANGPTL4 · Caloric restriction · Free fatty acids · angiopoietin · angiopoietin like protein 4 · beta adrenergic receptor stimulating agent · fatty acid · unclassified drug · ANGPTL4 protein, human · Angptl4 protein, mouse · antilipemic agent · Fiaf protein, rat · lipid emulsion · messenger RNA · salbutamol · adult · animal cell · article · blood sampling · caloric restriction · cell strain HepG2 · controlled study · enzyme linked immunosorbent assay · exercise · fatty acid blood level · female · gene expression · genetic variability · hepatoma cell · human · human cell · human experiment · intestine cell · male · mouse · muscle cell · nonhuman · normal human · priority journal · protein blood level · rat · animal · blood · cell culture · clinical trial · controlled clinical trial · genetic transfection · genetics · heart muscle cell · intestine · liver tumor · metabolism · middle aged · randomized controlled trial · time · upregulation · Adrenergic beta-Agonists · Adult · Albuterol · Angiopoietins · Animals · Antilipemic Agents · Caloric Restriction · Cells, Cultured · Enzyme-Linked Immunosorbent Assay · Exercise · Fat Emulsions, Intravenous · Fatty Acids, Nonesterified · Humans · Intestines · Liver Neoplasms · Male · Mice · Middle Aged · Myocytes, Cardiac · Rats · RNA, Messenger · Time Factors · Transfection · Up-Regulation · Young Adult
[Abstract]

6 Evidence for anti-inflammatory activity of statins and PPARα activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro
article 2004    
Author: Kleemann, R. · Verschuren, L. · Rooij, B.J. de · Lindeman, J. · Maat, M.M.de · Szalai, A.J. · Princen, H.M.G. · Kooistra, T.
Keywords: Biomedical Research · Antilipemic agent · C reactive protein · CCAAT enhancer binding protein · Cholesterol · Fenofibrate · Hydroxymethylglutaryl coenzyme A reductase inhibitor · I kappa B alpha · Immunoglobulin enhancer binding protein · Interleukin 1beta · Peroxisome proliferator activated receptor agonist · Peroxisome proliferator activated receptor alpha · Peroxisome proliferator activated receptor alpha agonist · Pirinixic acid · Protein p50 · Unclassified drug · Animal experiment · Animal model · Animal tissue · Antiinflammatory activity · Atherogenesis · Atherosclerosis · Cardiovascular risk · Cell culture · Cholesterol blood level · Controlled study · Hepatoma cell · Human cell · Inflammation · Liver cell · Mouse · Nonhuman · Transgenic mouse · Animals · C-Reactive Protein · Carcinoma, Hepatocellular · CCAAT-Enhancer-Binding Proteins · Cell Line, Tumor · Cholesterol · Down-Regulation · Gene Expression · Hepatocytes · Heptanoic Acids · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · I-kappa B Proteins · Interleukin-1 · Male · Mice · Mice, Transgenic · NF-kappa B · NF-kappa B p50 Subunit · Pyrroles · Receptors, Cytoplasmic and Nuclear · Simvastatin · Transcription Factors · Up-Regulation
[Abstract]

7 Niacin increases HDL by reducing hepatic expression and plasma levels of cholesteryl ester transfer protein in APOE*3Leiden.CETP mice
article 2008    
Author: Hoorn, J.W.A. van der · Haan, W. de · Berbée, J.P.P. · Havekes, L.M. · Jukema, J.W. · Rensen, P.C. · Princen, H.M.G.
Keywords: APOE*3Leiden.CETP transgenic mice · CETP · HDL-cholesterol · Hyperlipidemia · Niacin · cholesterol · cholesterol ester transfer protein · high density lipoprotein · high density lipoprotein cholesterol · low density lipoprotein cholesterol · nicotinic acid · triacylglycerol · antilipemic agent · CETP protein, human · messenger RNA · animal experiment · animal model · animal tissue · blood level · cholesterol blood level · controlled study · dose response · drug dose comparison · drug mechanism · female · gene activity · gene expression regulation · hypercholesterolemia · hypertriglyceridemia · kidney · lipid transport · lipoprotein blood level · liver · mouse · mouse strain · nonhuman · particle size · plasma clearance · priority journal · protein blood level · protein function · protein transport · transgenic mouse · triacylglycerol blood level · atherosclerosis · bile · blood · chemistry · disease model · drug effect · fat intake · feces · genetics · metabolism · time · upregulation · Animals · Antilipemic Agents · Apolipoprotein A-I · Apolipoprotein E3 · Atherosclerosis · Bile · Cholesterol Ester Transfer Proteins · Cholesterol, HDL · Dietary Fats · Disease Models, Animal · Dose-Response Relationship, Drug · Feces · Female · Humans · Liver · Mice · Mice, Transgenic · Niacin · RNA, Messenger · Time Factors · Triglycerides · Up-Regulation
[Abstract]

8 Mouse models for atherosclerosis and pharmaceutical modifiers
article 2007    
Author: Zadelaar, A.S.M. · Kleemann, R. · Verschuren, L. · Vries-van der Weij, J. de · Hoorn, J. van der · Princen, H.M. · Kooistra, T.
Keywords: Biology · Biomedical Research · ACE inhibitors · AT1 receptor antagonists · Atherosclerosis · LXR · Mouse models · Pharmaceutical drugs · PPAR · Statins · atorvastatin · avasimibe · candesartan · captopril · cholesterol acyltransferase inhibitor · dipeptidyl carboxypeptidase inhibitor · hydralazine · hydroxymethylglutaryl coenzyme A reductase inhibitor · irbesartan · losartan · ly 465608 · n (2,2,2 trifluoroethyl) n [4 [2,2,2 trifluoro 1 hydroxy 1 (trifluoromethoxy)ethyl]phenyl]benzenesulfonamide · olmesartan · perindopril · peroxisome proliferator activated receptor alpha agonist · pirinixic acid · pitavastatin · pravastatin · quinapril · ramipril · rosuvastatin · simvastatin · telmisartan · temocapril · unindexed drug · valsartan · zofenopril · antihypertensive agent · antilipemic agent · apolipoprotein E · atherosclerosis · pathophysiology · sensitivity and specificity · Animals · Antihypertensive Agents · Antilipemic Agents · Apolipoproteins E · Atherosclerosis · Disease Models, Animal · Dose-Response Relationship, Drug · Drug Administration Schedule · Dyslipidemias · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hypertension · Male · Mice · Mice, Knockout · Mice, Transgenic · Sensitivity and Specificity
[Abstract]

9 Apolipoprotein E*3-Leiden transgenic mice mode for hypolipidaemic drugs
article 1998    
Author: Vlijmen, B.J.M. van · Pearce, N.J. · Bergö, M. · Staels, B. · Yates, J.W. · Gribble, A.D. · Bond, B.C. · Hofker, M.H. · Havekes, L.M. · Groot, P.H.E.
Keywords: Pharmacology · ±(3R*,5S*)3-Carboxy-11-(2,4-dichlorophenyl)-3,5-dihydroxyundecanoic acid, 5-ring lactone · CAS 154566-12-8 · Gemfibrozil · Hypolipidaemic drugs, testing in transgenic mice · Lovastatin · SB 204990, hypolipidaemic effect · 3 carboxy 11 (2,4 dichlorophenyl) 3,5 dihydroxyundecanoic acid · Antilipemic agent · Apolipoprotein c3 · Apolipoprotein e3 · Cholesterol · Gemfibrozil · High density lipoprotein · Lipoprotein lipase · Low density lipoprotein · Messenger rna · Mevinolin · Sb 204990 · Triacylglycerol · Unclassified drug · Very low density lipoprotein · Anticoagulant agent · Apolipoprotein E · Apolipoprotein E3 · Heparin · Lactone · Lipid · Messenger RNA · SB 204990 · Animal model · Animal tissue · Atherosclerosis · Cholesterol blood level · Controlled study · Dose response · Drug effect · Enzyme activity · Gene expression · Hyperlipidemia · Lipoprotein blood level · Male · Mouse · Nonhuman · Oral drug administration · Transgenic mouse · Animal · Biosynthesis · Blood · C57BL mouse · Drug screening · Genetics · Liver · Metabolism · hysiology · Animals · Anticoagulants · Antilipemic Agents · Apolipoprotein E3 · Apolipoproteins E · Cholesterol · Drug Evaluation, Preclinical · Gemfibrozil · Heparin · Lactones · Lipids · Lipoprotein Lipase · Liver · Lovastatin · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · RNA, Messenger · Triglycerides
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 9 of 9 found. | Sort by date