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1 Inhibition of matrix metalloproteinases by bisphosphonates may in part explain their effects in the treatment of multiple myeloma [6]
article 2000    
Author: Teronen, O. · Laitinen, M. · Salo, T. · Hanemaaijer, R. · Heikkilä, P. · Konttinen, Y.T. · Sorsa, T.
Keywords: Pharmacology · Antineoplastic Agents · Breast Neoplasms · Diphosphonates · Down-Regulation · Enzyme Inhibitors · Female · Humans · Male · Matrix Metalloproteinases · Multiple Myeloma · Neoplasm Metastasis

2 Effects of aminoglutethimide alone and in combination with surgical castration, on pancreatic carcinogenesis in rats and hamsters
article 1995    
Author: Visser, C.J.T. · Meijers, M. · Garderen-Hoetmer, A. van · Klijn, J.G.M. · Foekens, J.A. · Woutersen, R.A.
Keywords: Biology · Aminoglutethimide · Animal · Antineoplastic Agents · Azaserine · Body Weight · Combined Modality Therapy · Hamsters · Male · Mesocricetus · Orchiectomy · Organ Weight · Pancreatic Neoplasms · Rats · Rats, Wistar · Support, Non-U.S. Gov't
[Abstract]

3 Biomonitoring human exposure to environmental carcinogenic chemicals
article 1996    
Author: Farmer, P.B. · Sepai, O. · Lawrence, R. · Autrup, H. · Nielsen, P.S. · Baan, R.A. · Delft, J.H.M. van · Steenwinkel, M.J.S.T. · et al.
Keywords: Nutrition · Antineoplastic Agents, Alkylating · Blood Proteins · Carcinogens, Environmental · Case-Control Studies · DNA Adducts · DNA Damage · Environmental Exposure · Environmental Monitoring · Epichlorohydrin · Ethylene Oxide · Humans · Methylene Chloride · Mutagens · Nitrogen Oxides · Occupational Exposure · Petroleum · Polycyclic Hydrocarbons, Aromatic · Styrene · Styrenes
[Abstract]

4 Influence of single and multiple doses of amifostine on the efficacy and the pharmacokinetics of carboplatin in mice
article 1997    
Author: Korst, A.E.C. · Boven, E. · Sterre, M.L.T. van der · Fichtinger-Schepman, A.M.J. · Vijgh, W.J.F. van der
Keywords: Amifostine · Anti-tumour activity · Carboplatin · Hypothermia · Pharmacokinetics · Amifostine · Animals · Antineoplastic Agents · Body Temperature · Carboplatin · DNA Adducts · Drug Administration Schedule · Drug Synergism · Female · Humans · Mice · Mice, Nude · Neoplasm Transplantation · Ovarian Neoplasms · Platinum · Radiation-Protective Agents · Transplantation, Heterologous
[PDF] [Abstract]

5 Role of metallothionein in cisplatin sensitivity of germ-cell tumours
article 2000    
Author: Meijer, C. · Timmer, A. · Vries, E.G.E.de · Groten, J.P. · Knol, A. · Zwart, N. · Dam, W.A. · Sleijfer, D.Th. · Mulder, N.H.
Keywords: Nutrition · Cisplatin · Glutathione peroxidase · Metallothionein · Protein p53 · Article · Cellular distribution · Colon carcinoma · Disease association · Drug sensitivity · Germ cell tumor · Human · Human cell · Immunohistochemistry · Priority journal · Protein expression · Testis tumor · Antineoplastic Agents · Cisplatin · Colonic Neoplasms · Drug Screening Assays, Antitumor · Germinoma · Humans · Immunohistochemistry · Male · Metallothionein · Testicular Neoplasms · Tumor Cells, Cultured · Tumor Suppressor Protein p53 · Food and Nutrition · Healthy Living
[Abstract]

6 Effect of short-term dietary administration of eugenol in humans
article 1996    
Author: Rompelberg, C.J.M. · Vogels, J.T.W.E. · Vogel, N. de · Bruijntjes-Rozier, G.C.D.M. · Stenhuis, W.H. · Bogaards, J.J.P. · Verhagen, H.
Keywords: Nutrition · Antigenotoxicity · Eugenol · GST · antitoxin · eugenol · glutathione transferase · mitomycin c · vinblastine · article · biotransformation · blood sampling · chromosome aberration · controlled study · enzyme activity · erythrocyte · genotoxicity · human · human experiment · leukocyte · male · micronucleus · priority journal · xenobiotic metabolism · Acetaminophen · Adult · Antibiotics, Antineoplastic · Antineoplastic Agents, Phytogenic · Biotransformation · Cells, Cultured · Chromosome Aberrations · Cross-Over Studies · Erythrocytes · Eugenol · Glutathione Transferase · Humans · Intervention Studies · Leukocytes · Liver · Magnetic Resonance Spectroscopy · Male · Mitomycin · Vinblastine
[Abstract]

7 Glutathione conjugation of the cytostatic drug ifosfamide and the role of human glutathione S-transferases
article 1995    
Author: Dirven, H.A.A.M. · Megens, L. · Oudshoorn, M.J. · Dingemanse, M.A. · Ommen, B. van · Bladeren, P.J. van
Keywords: Nutrition · Glutathione · Glutathione transferase · Ifosfamide · Cancer chemotherapy · Drug conjugation · Drug detoxification · Drug resistance · Enzyme activity · Human · Human tissue · Leukemia · Lymphoma · Solid tumor · Antineoplastic Agents, Alkylating · Biotransformation · Chromatography, High Pressure Liquid · Drug Resistance, Neoplasm · Glutathione · Glutathione Transferase · Human · Ifosfamide · Isoenzymes · Magnetic Resonance Spectroscopy · Metabolic Detoxication, Drug · Spectrometry, Mass, Fast Atom Bombardment · Support, Non-U.S. Gov't
[Abstract]

8 Prophage induction and mutagenicity of a series of anti-tumour platinum(II) and platinum(IV) co-ordination complexes
article 1982    
Author: Mattern, I.E. · Cocchiarella, L. · Kralingen, C.G. van · Lohman, P.H.M.
Keywords: Biology · Antineoplastic agent · Cisplatin · Platinum derivative · Ames test · Animal experiment · Cis platinum complex · Heredity · In vitro study · Metabolism · Mutagenicity · Prophage · Prophage induction · Salmonella · Antineoplastic Agents · Bacteriophage lambda · Histidine · Mutagenicity Tests · Mutagens · Platinum · Salmonella typhimurium · Support, Non-U.S. Gov't · Virus Activation
[Abstract]

9 Platinum compounds with anti-tumour activity
article 1980    
Author: Plooy, A.C.M. · Lohman, P.H.M.
Keywords: Biology · Antineoplastic agent · Cisplatin · Platinum derivative · Radioisotope · Animal experiment · Cytotoxicity · DNA damage · DNA strand breakage · DNA synthesis · Drug toxicity · Endocrine system · Female genital system · Heredity · In vitro study · Intoxication · Mutagenesis · Mutagenicity · Ovary cell · Structure activity relation · Thymidine h 3 · Alkalies · Animal · Antineoplastic Agents · DNA · DNA Replication · Hamsters · In Vitro · Platinum · Structure-Activity Relationship · Support, Non-U.S. Gov't
[Abstract]

10 A probabilistic assessment of the impact of interventions on oncology nurses' exposure to antineoplastic agents
article 2006    
Author: Meijster, T. · Fransman, W. · Hemmen, J. van · Kromhout, H. · Heederik, D. · Tielemans, E.
Keywords: Nutrition · Food and Chemical Risk Analysis · antineoplastic agent · cyclophosphamide · controlled study · health care policy · human · incidence · job performance · major clinical study · medical information · nurse · occupational exposure · oncology · outcome assessment · pregnancy · priority journal · protective clothing · review · statistical analysis · urine · Antineoplastic Agents · Health Policy · Humans · Monte Carlo Method · Netherlands · Occupational Exposure · Oncologic Nursing · Probability · Skin
[Abstract]

11 Pharmacokinetics of carboplatin with and without amifostine in patients with solid tumors
article 1997    
Author: Korst, A.E.C. · Sterre, M.L.T. van der · Eeltink, C.M. · Fichtinger-Schepman, A.M.J. · Vermorken, J.B. · Vijgh, W.J.F. van der
Keywords: Pharmacology · Amifostine · Carboplatin · Adult · Blood sampling · Clinical article · Clinical trial · Controlled clinical trial · Creatinine blood level · Creatinine clearance · Drug blood level · Drug efficacy · Drug half life · Enzyme linked immunosorbent assay · Female · Human · Intravenous drug administration · Male · Phase 1 clinical trial · Solid tumor · Amifostine · Animals · Antineoplastic Agents · Carboplatin · Dose-Response Relationship, Drug · Half-Life · Kidney · Kidney Function Tests · Metabolic Clearance Rate · Mice · Mice, Nude · Neoplasms
[Abstract]

12 Influence of amifostine on the pharmacokinetics of cisplatin in cancer patients
article 1998    
Author: Korst, A.E.C. · Sterre, M.L.T. van der · Gall, H.E. · Fichtinger-Schepman, A.M.J. · Vermorken, J.B. · Vijgh, W.J.F. van der
Keywords: Nutrition · Amifostine · Cisplatin · Creatinine · Adult · Aged · Area under the curve · Clinical article · Creatinine blood level · Dna adduct · Dna drug complex · Drug blood level · Drug effect · Drug half life · Female · Human · Intravenous drug administration · Kidney function · Male · Malignant neoplastic disease · Priority journal · Amifostine · Antineoplastic Agents · Cisplatin · DNA Adducts · Drug Interactions · Female · Half-Life · Hemofiltration · Humans · Leukocytes · Male · Middle Aged · Neoplasms · Platinum · Radiation-Protective Agents
[Abstract]

13 Acetyldinaline: A new oral cytostatic drug with impressive differential activity against leukemic cells and normal stem cells - Preclinical studies in a relevant rat model for human acute myelocytic leukemia
article 1993    
Author: El-Beltagi, H.M. · Martens, A.C.M. · Lelieveld, P. · Haroun, E.A. · Hagenbeek, A.
Keywords: Administration, Oral · Animal · Antineoplastic Agents · Bone Marrow · Bone Marrow Cells · Cell Differentiation · Cell Survival · Clone Cells · Comparative Study · Disease Models, Animal · Dose-Response Relationship, Drug · Drug Administration Schedule · Drug Evaluation · Drug Screening Assays, Antitumor · Hematopoietic Stem Cells · Leukemia, Myelocytic, Acute · Male · Phenylenediamines · Rats · Rats, Inbred BN · Support, Non-U.S. Gov't · Tumor Cells, Cultured
[Abstract]

14 Melphalan antitumor efficacy and hepatotoxicity: The effect of variable infusion duration in the hepatic artery
article 2003    
Author: Rothbarth, J. · Woutersen, R.A. · Sparidans, R.W. · Velde, C.J.H. van de · Mulder, G.J.
Keywords: Toxicology · Toxicology and Applied Pharmacology · melphalan · animal cell · animal experiment · animal model · animal tissue · antineoplastic activity · article · biliary tract fibrosis · body weight · colon tumor · controlled study · drug efficacy · drug infusion · drug liver level · drug tumor level · hepatic artery · high performance liquid chromatography · liver metastasis · liver perfusion · liver toxicity · nonhuman · priority journal · rat · Animals · Antineoplastic Agents, Alkylating · Disease Models, Animal · Hepatic Artery · Infusions, Intra-Arterial · Liver Neoplasms · Male · Melphalan · Neoplasm Transplantation · Rats · Treatment Outcome
[Abstract]

15 Nurses with dermal exposure to antineoplastic drugs: Reproductive outcomes
article 2007    
Author: Fransman, W. · Roeleveld, N. · Peelen, S. · Kort, W.de · Kromhout, H. · Heederik, D.
Keywords: Toxicology · Food and Chemical Risk Analysis · antineoplastic agent · cyclophosphamide · adult · article · calculation · confidence interval · congenital malformation · drug exposure · female · fertility · hazard assessment · human · logistic regression analysis · nurse · occupational exposure · oncology · outcome assessment · pregnancy · premature labor · priority journal · questionnaire · reproductive health · risk assessment · self report · sex · spontaneous abortion · stillbirth · survival · task performance · time series analysis · Adult · Antineoplastic Agents · Female · Gloves, Surgical · Humans · Infertility, Female · Netherlands · Nurses · Occupational Exposure · Pregnancy · Pregnancy Outcome · Skin Absorption
[Abstract]

16 Retinoid metabolism and all-trans retinoic acid-induced growth inhibition in head and neck squamous cell carcinoma cell lines
article 1997    
Author: Braakhuis, B.J.M. · Klaassen, I. · Leede, B.M. van der · Cloos, J. · Brakenhoff, R.H. · Copper, M.P. · Teerlink, T. · Hendriks, H.F.J. · Saag, P.T. van der · Snow, G.B.
Keywords: CRABP-II · Head and neck cancer · Metabolism · Squamous · alitretinoin · isotretinoin · messenger RNA · retinoic acid · retinoic acid binding protein · cancer cell culture · cancer inhibition · cell metabolism · controlled study · drug blood level · drug metabolism · head cancer · homeostasis · human cell · neck cancer · squamous cell carcinoma · Antineoplastic Agents · Carcinoma, Squamous Cell · Cell Division · Chromatography, High Pressure Liquid · Culture Media · Head and Neck Neoplasms · Humans · Receptors, Retinoic Acid · Retinoids · Tretinoin · Tumor Cells, Cultured
[PDF] [Abstract]

17 Postulating a dermal pathway for exposure to anti-neoplastic drugs among hospital workers. Applying a conceptual model to the results of three workplace surveys
article 2000    
Author: Kromhout, H. · Hoek, F. · Uitterhoeve, R. · Huijbers, R. · Overmars, R.F. · Anzion, R. · Vermeulen, R.
Keywords: Cyclophosphamide · Dermal exposure · Hospital · Nurses · Drug infusion · Drug products · Mass transfer · Physiological models · Skin · Toxic materials · Trace analysis · Anti neoplastic drugs · Dermal exposure · Intravenous drug infusion · Industrial hygiene · Antineoplastic agent · Contamination · Fluorescence · Hospital personnel · Occupational health · Air Pollutants, Occupational · Antineoplastic Agents · Benzenesulfonates · Environmental Monitoring · Fluorescent Dyes · Human · Models, Biological · Nursing Staff, Hospital · Observer Variation · Occupational Exposure · Risk Assessment · Skin Absorption · Support, Non-U.S. Gov't · Workplace
[Abstract]

18 Effect of cisplatin exposure on platinum accumulation and growth inhibition in human neoplastic and normal squamous epithelial cells of the mucosa of the upper-aerodigestive tract
article 1999    
Author: Braakhuis, B.J.M. · Welters, M.J.P. · Cloos, J. · Pankras, J.E. · Smeets, S.J. · Fichtinger-Schepman, A.-M.J.
Keywords: Nutrition · Cisplatin · Head and neck · Keratinocytes · Non-malignant cells · Pt accumulation · Squamous cells · Cisplatin · Platinum · Adult · Antineoplastic activity · Cancer cell culture · Colorimetry · Controlled study · Drug accumulation · Epithelium cell · Female · Growth inhibition · Head and neck cancer · Human · Human cell · Keratinocyte · Male · Palate · Priority journal · Squamous cell · Squamous epithelium · Antineoplastic Agents · Carcinoma, Squamous Cell · Cell Division · Cisplatin · Epithelial Cells · Female · Head and Neck Neoplasms · Humans · Male · Middle Aged · Platinum · Tumor Cells, Cultured · Uvula
[Abstract]

19 The potential of platinum-DNA adduct determination in ex vivo treated tumor fragments for the prediction of sensitivity to cisplatin chemotherapy
article 1999    
Author: Welters, M.J.P. · Braakhuis, B.J.M. · Jacobs-Bergmans, A.J. · Kegel, A. · Baan, R.A. · Vijgh, W.J.F. van der · Fichtinger-Schepman, A.M.J.
Keywords: Nutrition · Ex vivo · Response · Antineoplastic agent · Animal experiment · Animal model · Cancer chemotherapy · Cancer graft · Clinical article · Head and neck carcinoma · Mouse · Nonhuman · Nude mouse · Prediction · Squamous cell carcinoma · Testis cancer · Tumor biopsy · Clinical trial · Comparative study · Culture technique · Drug resistance · Genetics · Head and neck tumor · Prediction and forecasting · Testis tumor · Adult · Aged · Antineoplastic Agents · Carcinoma, Squamous Cell · Cisplatin · Culture Techniques · DNA Adducts · Drug Resistance, Neoplasm · Female · Head and Neck Neoplasms · Humans · Male · Middle Aged · Predictive Value of Tests · Sensitivity and Specificity · Testicular Neoplasms
[Abstract]

20 Inhibition of apolipoprotein(a) synthesis in cynomolgus monkey hepatocytes by retinoids via involvement of the retinoic acid receptor
article 1999    
Author: Neele, D.M. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Biology · Apolipoprotein(a) · Cynomolgus monkey hepatocytes · RAR · Retinoids · RXR · alitretinoin · apolipoprotein A · isotretinoin · retinoic acid · retinoic acid receptor · retinoid · retinoid X receptor · retinol · animal cell · article · concentration response · controlled study · dose time effect relation · drug effect · enzyme linked immunosorbent assay · gene expression · lipoprotein synthesis · liver cell · monkey · nonhuman · priority journal · Animals · Antineoplastic Agents · Apolipoproteins A · Benzoates · Dose-Response Relationship, Drug · Ligands · Lipoproteins · Liver · Macaca fascicularis · Receptors, Retinoic Acid · Retinoid X Receptors · Retinoids · RNA, Messenger · Tetrahydronaphthalenes · Time Factors · Transcription Factors
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 29 found. Next | Sort by date