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1 Apolipoprotein CI knock-out mice display impaired memory functions
article 2011    
Author: Berbée, J.F.P. · Abildayeva, K. · Blokland, A. · Jansen, P.J. · Lütjohann, D. · Gautier, T. · Sijbrands, E. · Prickaerts, J. · Hadfoune, M. · Ramaekers, F.C.S. · Kuipers, F. · Rensen, P.C.N.
Keywords: Health · APOC1 · Apolipoprotein C-I · Cholesterol · Cognition and brain · Memory · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

2 Role of apoCs in lipoprotein metabolism : Functional differences between ApoC1, ApoC2, and ApoC3
article 1999    
Author: Jong, M.C. · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · Apolipoproteins · Lipoprotein lipase · Lipoproteins, VLDL · Mice, transgenic · Animals · Apolipoprotein C-I · Apolipoprotein C-II · Apolipoprotein C-III · Apolipoproteins C · Humans · Lipoproteins · Mice · Mice, Transgenic · Mutation
[Abstract]

3 Hyperlipidemia and cutaneous abnormalities in transgenic mice overexpressing human apolipoprotein C1
article 1998    
Author: Jong, M.C. · Gijbels, M.J.J. · Dahlmans, V.E.H. · Gorp, P.J.J. van · Koopman, S.-J. · Ponec, M. · Hofker, M.H. · Havekes, L.M.
Keywords: Health · Apolipoprotein C · Hypertriglyceridemia · Sebaceous glands · Sebum production · Triglycerides · Animals · Apolipoprotein C-I · Apolipoproteins C · Epidermis · Female · Humans · Hyperlipidemias · Lipids · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Skin Abnormalities
[Abstract]

4 Development of atopic dermatitis in mice transgenic for human apolipoprotein C1
article 2008    
Author: Nagelkerken, L. · Verzaal, P. · Lagerweij, T. · Persoon-Deen, C. · Berbee, J.F.P. · Prens, E.P. · Havekes, L.M. · Oranje, A.P.
Keywords: Biology · Physiological Sciences · apolipoprotein C1 · corticosteroid · immunoglobulin E · animal tissue · article · atopic dermatitis · controlled study · histopathology · inflammatory cell · lichenoid eruption · lipid metabolism · mouse · nonhuman · priority journal · protein expression · Administration, Topical · Adrenal Cortex Hormones · Animals · Apolipoprotein C-I · Dermatitis, Atopic · Eosinophils · Epidermis · Female · Humans · Immunoglobulin E · Liver · Male · Mast Cells · Mice · Mice, Transgenic · Neutrophils · Pruritus
[Abstract]

5 Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo
article 2008    
Author: Haan, W. de · Out, R. · Berbée, J.F.P. · Hoogt, C.C. van der · Dijk, K.W.v. · Berkel, T.J.C. van · Romijn, J.A. · Wouter Jukema, J. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Physiological Sciences · High density lipoprotein · Oxidized LDL · SR-BI · Transgenic mice · cholesterol ester · high density lipoprotein cholesterol · scavenger receptor BI · Adenovirus · animal cell · cholesterol metabolism · dose response · in vivo study · liver cell · mouse · nonhuman · particle size · protein expression · Adenoviridae · Animals · Apolipoprotein C-I · Cholesterol, HDL · Gene Transfer Techniques · Hepatocytes · Humans · Mice · Mice, Knockout · Scavenger Receptors, Class B · Adenoviridae · Murinae · Mus · Mus musculus
[Abstract]

6 Preoperative apolipoprotein CI levels correlate positively with the proinflammatory response in patients experiencing endotoxemia following elective cardiac surgery
article 2008    
Author: Schippers, E.F. · Berbée, J.F.P. · Disseldorp, I.M. van · Versteegh, M.I.M. · Havekes, L.M. · Rensen, P.C.N. · Dissel, J.T. van
Keywords: Biology · Biomedical Research · Aged · Apolipoprotein C-I · Cardiac Surgical Procedures · Cardiopulmonary Bypass · Cholesterol · Endotoxemia · Female · Humans · Intraoperative Care · Male · Middle Aged · Postoperative Complications · Predictive Value of Tests · Surgical Procedures, Elective · Tumor Necrosis Factor-alpha · ApoCI · Cardiopulmonary bypass · Endotoxemia · Endotoxin · SIRS · TNF-α
[Abstract]

7 Apolipoprotein CI aggravates atherosclerosis development in ApoE-knockout mice despite mediating cholesterol efflux from macrophages
article 2007    
Author: Westerterp, M. · Eck, M. van · Haan, W. de · Offerman, E.H. · Berkel, T.J.C. van · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · ApoCI · Cholesterol efflux · Hyperlipidemia · Macrophages · Transgenic mice · Triacylglycerol · Adipose tissue · Aorta root · Artery wall · Atherosclerosis · Protein expression · Statistical significance · Triacylglycerol blood level · Animals · Apolipoprotein C-I · Apolipoproteins E · Atherosclerosis · Bone Marrow Cells · Bone Marrow Transplantation · Cholesterol · Female · Gene Expression Regulation · Liver · Macrophages · Male · Mice · Mice, Knockout · Mice, Transgenic
[Abstract]

8 Hepatic lipid accumulation in apolipoprotein C-I-deficient mice is potentiated by cholesteryl ester transfer protein
article 2007    
Author: Gautier, T. · Tietge, U.J.F. · Boverhof, R. · Perton, F.G. · Le Guern, N. · Masson, D. · Rensen, P.C.N. · Havekes, L.M. · Lagrost, L. · Kuipers, F.
Keywords: Biology · Biomedical Research · Bile · Cholesterol · Triglycerides · bile acid · cholesterol · cholesterol ester transfer protein · high density lipoprotein · triacylglycerol · very low density lipoprotein · animal model · bile secretion · cholesterol blood level · controlled study · insulin metabolism · lipid metabolism · lipid storage · mouse · nonhuman · stress · Animals · Apolipoprotein C-I · Cholesterol Ester Transfer Proteins · Gallbladder · Lipids · Liver · Mice · Mice, Inbred C57BL · Mice, Knockout · Polymerase Chain Reaction · RNA
[PDF] [Abstract]

9 Reduced very-low-density lipoprotein fractional catabolic rate in apolipoprotein C1-deficient mice
article 1997    
Author: Jong, M.C. · Ree, J.H. van · Dahlmans, V.E.H. · Frants, R.R. · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · very low density lipoprotein · animal experiment · catabolism · controlled study · human · hyperlipoproteinemia · lipolysis · metabolism · mouse · nonhuman · priority journal · protein degradation · protein metabolism · transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins B · Apolipoproteins C · Cholesterol, Dietary · Female · Lipolysis · Lipoproteins, VLDL · Mice · Mice, Mutant Strains · Triglycerides · Ultracentrifugation · Animalia · Mus musculus
[Abstract]

10 Both lipolysis and hepatic uptake of VLDL are impaired in transgenic mice coexpressing human apolipoprotein E*3Leiden and human apolipoprotein C1
article 1996    
Author: Jong, M.C. · Dahlmans, V.E.H. · Gorp, P.J.J. van · Breuer, M.L. · Mol, M.J.T.M. · Zee, A. van der · Frants, R.R. · Hofker, M.H. · Havekes, L.M.
Keywords: Health · Transgenic mice · Triacylglycerol · Very low density lipoprotein · Animal experiment · Animal model · Atherosclerosis · Cholesterol blood level · Controlled study · Female · Lipolysis · Liver clearance · Liver metabolism · Male · Nonhuman · Protein transport · Transgenic mouse · Triacylglycerol blood level · Animals · Apolipoprotein C-I · Apolipoprotein E3 · Apolipoproteins C · Apolipoproteins E · Arteriosclerosis · Cholesterol · Cholesterol, Dietary · Gene Expression · Humans · Hyperlipoproteinemias · Lipolysis · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Triglycerides
[Abstract]

11 Apolipoprotein CI stimulates the response to lipopolysaccharide and reduces mortality in gram-negative sepsis.
article 2006    
Author: Berbée, J.F. · Hoogt, C.C. van der · Kleemann, R. · Schippers, E.F. · Kitchens, R.L. · Dissel, J.T. van · Bakker-Woudenberg, I.A. · Havekes, L.M. · Rensen, P.C.
Keywords: Biology · Drug effect · Gram negative bacterium · Immunology · Mortality · Mouse · Mouse mutant · Nucleotide sequence · Transgenic mouse · Animals · Antigen Presentation · Apolipoprotein C-I · Apolipoproteins C · Binding Sites · Conserved Sequence · Gram-Negative Bacteria · Humans · Immunity · Inflammation · Lipopolysaccharides · Macrophages · Mice · Mice, Knockout · Mice, Transgenic · Sepsis
[Abstract]

12 Wet-wrap treatment using dilutions of tacrolimus ointment and fluticasone propionate cream in human APOC1 (+/+) mice with atopic dermatitis
article 2009    
Author: Oranje, A.P. · Verbeek, R. · Verzaal, P. · Haspels, I. · Prens, E. · Nagelkerken, L.
Keywords: Biology · Biomedical Research · Apolipoprotein C · Atopic dermatitis · Mouse model · Transepidermal water loss · Wet-wrap treatment · apolipoprotein C1 · fluticasone propionate · tacrolimus · animal experiment · animal model · animal tissue · article · atopic dermatitis · clinical feature · controlled study · disease severity · drug effect · drug formulation · histopathology · mouse · nonhuman · occlusive dressing · priority journal · skin water loss · skinfold thickness · treatment response · weight reduction · Androstadienes · Animals · Apolipoprotein C-I · Bandages · Dermatitis, Atopic · Disease Progression · Dose-Response Relationship, Drug · Emollients · Humans · Mice · Mice, Transgenic · Models, Animal · Ointments · Tacrolimus
[Abstract]

13 Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification
article 2007    
Author: Westerterp, M. · Berbée, J.F.P. · Delsing, D.J.M. · Jong, M.C. · Gijbels, M.J.J. · Dahlmans, V.E.H. · Offerman, E.H. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Lipoprotein · Lipoprotein lipase · Skin · Triglyceride · very low density lipoprotein · animal cell · animal experiment · animal tissue · controlled study · electricity · esterification · female · in vitro study · mouse · nonhuman · phenotype · skin transplantation · wild type · Animals · Apolipoprotein C-I · Cells, Cultured · Enzyme-Linked Immunosorbent Assay · Esterification · Fatty Acids, Nonesterified · Female · Humans · Lipoproteins, VLDL · Macrophages · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Oleic Acid · Phenotype · Protein Binding · Skin · Skin Abnormalities · Skin Transplantation
[PDF] [Abstract]

14 Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL
article 2005    
Author: Berbée, J.F.P. · Hoogt, C.C. van der · Sundararaman, D. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Apolipoprotein C-I · Fatty acids · Lipid metabolism · Lipoprotein lipase · Triglycerides · Very low density lipoprotein · Lipoprotein receptor · Tritium · Very low density lipoprotein · Animal experiment · Animal model · Cholesterol blood level · Controlled study · Enzyme activity · Half life time · Hyperlipidemia · Hyperlipoproteinemia type 3 · Lipolysis · Mouse · Nonhuman · Pathophysiology · Protein expression · Transgenic mouse · Animals · Apolipoproteins · Apolipoproteins C · Apolipoproteins E · Humans · Hypertriglyceridemia · Lactoferrin · Lipoproteins, VLDL · Liver · Mice · Mice, Inbred C57BL · Mice, Transgenic · Phenotype · Time Factors
[PDF] [Abstract]

15 Apolipoprotein CI deficiency markedly augments plasma lipoprotein changes mediated by human cholesteryl ester transfer protein (CETP) in CETP transgenic/apoCI-knocked out mice
article 2002    
Author: Gautier, T. · Masson, D. · Jong, M.C. · Duverneuil, L. · Guern, N.L. · Deckert, V. · Barros, J.-P.P.de · Dumont, L. · Bataille, A. · Zak, Z. · Jiang, X.-C. · Tall, A.R. · Havekes, L.M. · Lagrost, L.
Keywords: Biology · Cholesterol · Chromatographic analysis · Esters · Proteins · Apolipoproteins · Biochemistry · High density lipoprotein · Very low density lipoprotein · Animal experiment · Concentration response · Controlled study · Gel permeation chromatography · Knockout mouse · Lipoprotein blood level · Mouse · Nonhuman · Protein deficiency · Protein expression · Transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins C · Carrier Proteins · Cholesterol Ester Transfer Proteins · Glycoproteins · Humans · Kinetics · Lipoproteins · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Animalia · Mus musculus
[PDF] [Abstract]

16 Plasma apolipoprotein CI correlates with increased survival in patients with severe sepsis
article 2008    
Author: Berbée, J.F.P. · Hoogt, C.C. van der · Haas, C.J.C. de · Kessel, K.P.M. van · Dallinga-Thie, G.M. · Romijn, J.A. · Havekes, L.M. · Leeuwen, H.J. van · Rensen, P.C.N.
Keywords: Health · Physiological Sciences · Apolipoprotein · Bacteria · Intensive care · Lipoprotein · Mortality · Sepsis · apolipoprotein A1 · apolipoprotein C1 · apolipoprotein C3 · high density lipoprotein cholesterol · lipid · low density lipoprotein cholesterol · triacylglycerol · adult · article · blood sampling · cholesterol blood level · clinical article · controlled study · correlation analysis · disease severity · female · hospitalization · human · intensive care unit · lipid blood level · male · outcome assessment · prospective study · protein blood level · sepsis · survival · Aged · Apolipoprotein C-I · Biological Markers · Female · Humans · Male · Middle Aged · Prospective Studies · Sepsis · Survival Analysis · Healthy for Life · Healthy Living
[Abstract]

17 Endogenous apoC-I increases hyperlipidemia in apoE-knockout mice by stimulating VLDL production and inhibiting LPL
article 2006    
Author: Westerterp, M. · Haan, W. de · Berbée, J.F.P. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Lipases transgenic mouse models · Very low density lipoprotein · apolipoprotein B · cholesterol · fatty acid · heparin · lipid · olive oil · triacylglycerol · very low density lipoprotein · animal experiment · animal tissue · cholesterol blood level · concentration response · controlled study · enzyme inhibition · gene dosage · gonad · hyperlipidemia · intestine absorption · knockout mouse · lipid absorption · lipid blood level · lipid metabolism · lipolysis · mouse · nonhuman · postprandial state · protein expression · triacylglycerol blood level · white adipose tissue · Animals · Apolipoprotein C-I · Apolipoproteins C · Apolipoproteins E · Cholesterol · Hyperlipidemias · Intestines · Lipase · Lipoprotein Lipase · Lipoproteins, VLDL · Liver · Mice · Mice, Knockout · Postprandial Period
[PDF] [Abstract]

18 Overexpression of APOC1 in obob mice leads to hepatic steatosis and severe hepatic insulin resistance
article 2004    
Author: Muurling, M. · Hoek, A.M. van den · Mensink, R.P. · Pijl, H. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Biology · Biomedical Research · Free fatty acid metabolism · Hepatic fat accumulation · Lipid metabolism · Peroxisome proliferator-activated receptor-γ · Rosiglitazone · Diacylglycerol · Glucose · Ketone body · Peroxisome proliferator activated receptor gamma · Rosiglitazone · Triacylglycerol · Adipose tissue · Animal experiment · Animal model · Animal tissue · APOC1 gene · Cholesterol blood level · Controlled study · Fatty acid metabolism · Gene · Gene overexpression · Gluconeogenesis · Glucose blood level · Glucose transport · Hyperglycemia · Hyperinsulinemia · Hyperlipidemia · Insulin blood level · Insulin resistance · Lipid metabolism · Lipid storage · Mouse · Nonhuman · Obesity · Transgenic mouse · Triacylglycerol blood level · Weight reduction · Animals · Apolipoprotein C-I · Apolipoproteins C · Blood Glucose · Body Weight · Fatty Acids · Fatty Liver · Gene Expression · Humans · Hyperglycemia · Hyperinsulinism · Hyperlipidemias · Insulin · Insulin Resistance · Mice · Mice, Transgenic
[PDF] [Abstract]

19 Hyperlipidaemia is associated with increased insulin-mediated glucose metabolism, reduced fatty acid metabolism and normal blood pressure in transgenic mice overexpressing human apolipoprotein C1
article 2001    
Author: Koopmans, S.J. · Jong, M.C. · Que, I. · Dahlmans, V.E.H. · Pijl, H. · Radder, J.K. · Frölich, M. · Havekes, L.M.
Keywords: Biology · APOC1 · Hypertension · Insulin resistance · Insulin resistance syndrome · Lipoprotein · NEFA · Fatty acid · Palmitic acid · Triacylglycerol · Tritium · Very low density lipoprotein · Adipose tissue · Animal model · Animal tissue · Blood pressure · Cholesterol blood level · Clearance · Controlled study · Fatty acid metabolism · Gene overexpression · Glucose blood level · Glucose clamp technique · Glucose metabolism · Glycogen synthesis · Glycolysis · Heart rate · Hyperinsulinemia · Hyperlipidemia · Hypertension · In vivo study · Infusion · Insulin resistance · Lipid transport · Lipogenesis · Mean arterial pressure · Mouse · Nonhuman · Skeletal muscle · Transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins C · Blood Glucose · Blood Pressure · Cholesterol · Fatty Acids, Nonesterified · Gene Expression · Glucose · Glucose Clamp Technique · Glycogen · Humans · Hyperlipidemias · Insulin · Lipid Metabolism · Liver · Mice · Mice, Transgenic · Muscle, Skeletal · Palmitic Acid · Triglycerides · Tritium
[Abstract]

20 Human apolipoprotein C-I expression in mice impairs learning and memory functions
article 2008    
Author: Abildayeva, K. · Berbée, J.F.P. · Blokland, A. · Jansen, P.J. · Hoek, F.J. · Meijer, O. · Lütjohann, D. · Gautier, T. · Pillot, T. · Vente, J.de · Havekes, L.M. · Ramaekers, F.C.S. · Kuipers, F. · Rensen, P.C.N. · Mulder, M.
Keywords: Health · Physiological Sciences · β-amyloid · Alzheimer's disease · Apolipoprotein E · Morris water maze task · Object recognition task · amyloid beta protein · apolipoprotein E · campesterol · cholestanol · cholesterol · cholesterol derivative · desmosterol · lanosterol · lathosterol · lysophosphatidylcholine · lysophosphatidylethanolamine · messenger RNA · phosphatidylcholine · phosphatidylethanolamine · phosphatidylinositol · phosphatidylserine · sitosterol · sphingomyelin · unclassified drug · animal cell · animal experiment · animal model · animal tissue · apoptosis · astrocyte · brain level · cell viability · controlled study · disease exacerbation · endothelium cell · female · hippocampus · human tissue · learning disorder · lipid metabolism · maze test · memory disorder · mouse · nerve cell necrosis · nonhuman · protein aggregation · protein expression · recognition · task performance · transgenic mouse · wild type · animal · C57BL mouse · gene expression regulation · genetics · metabolism · Animals · Apolipoprotein C-I · Gene Expression Regulation · Humans · Immunohistochemistry · Learning · Memory · Mice · Mice, Inbred C57BL · Mice, Transgenic · RNA, Messenger · Tissue Culture Techniques
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 20 found. | Sort by date