Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 20 of 89 found. Next | Sort by date

1 Suppression of cholesterol synthesis in cultured fibroblasts from a patient with homozygous familial hypercholesterolemia by her own low density lipoprotein density fraction. A possible role of apolipoprotein E
article 1980    
Author: Havekes, L. · Vermeer, B.J. · Wit, E. de
Keywords: Biology · Apolipoproteins · Apolipoproteins E · Cells, Cultured · Cholesterol · Female · Fibroblasts · Homozygote · Human · Hypercholesterolemia, Familial · Lipoproteins, LDL · Phospholipids
[Abstract]

2 Stimulation of the in Vivo Production of Very Low Density Lipoproteins by Apolipoprotein E Is Independent of the Presence of the Low Density Lipoprotein Receptor
article 2001    
Author: Teusink, B. · Mensenkamp, A.R. · Boom, H. van der · Kuipers, F. · Dijk, K.W. van · Havekes, L.M.
Keywords: Animalia · Gillia · Animals · Apolipoproteins E · Lipoproteins, VLDL · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Receptors, LDL
[PDF] [Abstract]

3 Transgenic mouse models to study the role of APOE in hyperlipidemia and atherosclerosis
article 1998    
Author: Hofker, M.H. · Vlijmen, B.J.M. van · Havekes, L.M.
Keywords: Health · APOE · Apolipoprotein · Cholesterol · Gene targeting · Lipoprotein · Triglyceride · Animals · Apolipoproteins E · Arteriosclerosis · Disease Models, Animal · Humans · Hyperlipidemias · Mice · Mice, Transgenic
[Abstract]

4 Severe learning deficits in apolipoprotein E-knockout mice in a water maze task
article 1997    
Author: Oitzl, M.S. · Mulder, M. · Lucassen, P.J. · Havekes, L.M. · Grootendorst, J. · Kloet, E.R. de
Keywords: Alzheimer' s disease · Animals · Apolipoproteins E · Learning Disorders · Male · Maze Learning · Mice · Mice, Knockout · Motor Activity · Reference Values · Swimming
[Abstract]

5 Plasma levels of apolipoprotein E and cognitive function in old age
bookPart 2007    
Author: Mooijaart, S.P. · Vliet, P. van · Heemst, D. van · Rensen, P.C.N. · Berbée, J.F.P. · Jolles, J. · Craen, A.J.M. de · Westendorp, R.G.J.
Keywords: Biology · Biomedical Research · Dementia · Aged · Aged, 80 and over · Aging · Apolipoproteins E · Cardiovascular Diseases · Cerebrovascular Disorders · Cholesterol · Cognition Disorders · Dementia · Female · Genotype · Humans · Male · Neuropsychological Tests · Risk Factors
[Abstract]

6 Atherosclerosis in APOE(*)3-Leiden transgenic mice from proliferative to atheromatous stage
article 1999    
Author: Lutgens, E. · Daemen, M. · Kockx, M. · Doevendans, P. · Hofker, M. · Havekes, L. · Wellens, H. · Muinck, E.D. de
Keywords: Biology · Apoptosis · Atherosclerosis · Genetics · Animals · Apolipoprotein E3 · Apolipoproteins E · Apoptosis · Arteriosclerosis · Diet, Atherogenic · Disease Models, Animal · Disease Progression · DNA · Female · Foam Cells · Male · Mice · Mice, Transgenic · Phenotype
[Abstract]

7 Hyperlipidemia in APOE2 transgenic mice is ameliorated by a truncated apoE variant lacking the C-terminal domain
article 2003    
Author: Gerritsen, G. · Kypreos, K.E. · Zee, A. van der · Teusink, B. · Zannis, V.I. · Havekes, L.M. · Dijk, K.W. van
Keywords: Biology · Adenoviridae · Animals · Apolipoprotein E2 · Apolipoprotein E4 · Apolipoproteins E · Cholesterol · Humans · Hyperlipidemias · Lipids · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Protein Isoforms · Protein Structure, Tertiary · Triglycerides
[PDF] [Abstract]

8 Serum apolipoprotein e level is not increased in Alzheimer's disease : The Rotterdam study
article 1998    
Author: Slooter, A.J.C. · Knijff, P. de · Hofman, A. · Cruts, M. · Breteler, M.M.B. · Broeckhoven, C. van · Havekes, L.M. · Duijn, C.M. van
Keywords: Health · Alzheimer's disease · Apolipoprotein E · Atherosclerosis · Dementia · Plasma · Serum level · Aged · Aged, 80 and over · Alzheimer Disease · Apolipoproteins E · Cohort Studies · Female · Genotype · Humans · Male · Middle Aged
[Abstract]

9 Mice expressing only the mutant APOE3Leiden gene show impaired VLDL secretion
article 2001    
Author: Mensenkamp, A.R. · Teusink, B. · Baller, J.F.W. · Wolters, H. · Havinga, R. · Dijk, K.W. van · Havekes, L.M. · Kuipers, F.
Keywords: Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Fatty Liver · Lipid Metabolism · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Protein Isoforms · RNA, Messenger · Triglycerides
[Abstract]

10 Use of transgenic mice in lipoprotein metabolism and atherosclerosis research
article 1997    
Author: Havekes, L.M. · Vlijmen, B.J.M. van · Jong, M.C. · Dijk, K.W. van · Hofker, M.H.
Keywords: Biology · Age Factors · Animals · Apolipoprotein E3 · Apolipoproteins C · Apolipoproteins E · Arteriosclerosis · Cholesterol · Female · Humans · Lipids · Lipoproteins · Lipoproteins, VLDL · Male · Mice · Mice, Transgenic · Sex Factors · Animalia · Mus musculus
[Abstract]

11 A rapid micromethod for apolipoprotein E phenotyping directly in serum
article 1987    
Author: Havekes, L.M. · Knijff, P. de · Beisiegel, U. · Havinga, J. · Smit, M. · Klasen, E.
Keywords: Apolipoprotein e · Blood and hemopoietic system · Human cell · Immunoblotting · Isoelectric focusing · Methodology · Micrometer · Serum · Apolipoproteins E · Chloroform · Guanidine · Guanidines · Human · Hyperlipoproteinemia Type III · Isoelectric Focusing · Methanol · Phenotype
[PDF] [Abstract]

12 Association between apolipoprotein E ε4 and the rate of cognitive decline in community-dwelling elderly individuals with and without dementia
article 1998    
Author: Jonker, C. · Schmand, B. · Lindeboom, J. · Havekes, L.M. · Launer, L.J.
Keywords: Health · Aged · Aged, 80 and over · Alleles · Apolipoproteins E · Cognition · Dementia · Female · Humans · Longitudinal Studies · Male · Neuropsychological Tests · Phenotype · Residence Characteristics · Severity of Illness Index
[Abstract]

13 Apolipoprotein E genotype, atherosclerosis, and cognitive decline : The Rotterdam study
article 1998    
Author: Slooter, A.J.C. · Duijn, C.M. van · Bots, M.L. · Ott, A. · Breteler, M.B. · Voecht, J. de · Wehnert, A. · Knijff, P. de · Havekes, L.M. · Grobbee, D.E. · Broeckhoven, C. van · Hofman, A.
Keywords: Health · Netherlands · Aged · Apolipoproteins E · Arteriosclerosis · Cognition Disorders · Female · Follow-Up Studies · Genotype · Humans · Male · Middle Aged · Netherlands · Psychiatric Status Rating Scales
[Abstract]

14 Reduced levels of cholesterol, phospholipids, and fatty acids in cerebrospinal fluid of Alzheimer disease patients are not related to apolipoprotein E4
article 1998    
Author: Mulder, M. · Ravid, R. · Kloet, J.E.R. de · Haasdijk, E.D. · Julk, J. · Boom, J. van der · Havekes, L.M.
Keywords: Biology · Cerebrospinal fluid · Lipids · Aged · Aged, 80 and over · Alzheimer Disease · Apolipoprotein E4 · Apolipoproteins E · Brain · Cholesterol · Fatty Acids · Female · Genotype · Homeostasis · Humans · Male · Phospholipids · Reference Values
[Abstract]

15 Accelerated atherosclerosis and calcification in vein grafts: A study in APOE*3 Leiden transgenic mice
article 2002    
Author: Lardenoye, J.H.P. · Vries, M.R. de · Löwik, C.W.G.M. · Xu, Q. · Dhore, C.R. · Cleutjens, J.P.M. · Hinsbergh, V.W.M. van · Bockel, J.H. van · Quax, P.H.A.
Keywords: Animals · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Calcinosis · Foam Cells · Graft Rejection · Hypercholesterolemia · Kinetics · Lipids · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Veins
[Abstract]

16 Plasma levels of apolipoprotein E and risk of stroke in old age
bookPart 2007    
Author: Vliet, P. van · Mooijaart, S.P. · Craen, A.J.M. de · Rensen, P.C.N. · Heemst, D. van · Westendorp, R.G.J.
Keywords: Biology · Biomedical Research · Atherosclerosis · Elderly · Plasma apolipoprotein E levels · Stroke · Aged, 80 and over · Alleles · Apolipoproteins E · Atherosclerosis · Cerebrovascular Accident · Cerebrovascular Disorders · Female · Genetic Predisposition to Disease · Genotype · Humans · Ischemia · Male · Risk · Risk Factors
[Abstract]

17 Hyperlipidemia of ApoE2(Arg158-Cys) and ApoE3-Leiden transgenic mice is modulated predominantly by LDL receptor expression
article 1999    
Author: Dijk, K.W. van · Vlijmen, B.J.M. van · Winther, M.P.J. de · Hof, B. van 't · Zee, A. van der · Boom, H. van der · Havekes, L.M. · Hofker, M.H.
Keywords: Biology · Apolipoprotein E · Hypertriglyceridemia · LDL receptor · LDL receptor-related protein · VLDL triglyceride lipolysis · Animals · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Cholesterol, VLDL · Gene Expression · Hypertriglyceridemia · Lipolysis · Mice · Mice, Knockout · Point Mutation · Receptors, LDL · Triglycerides
[Abstract]

18 Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice
article 1999    
Author: Winther, M.P.J. de · Gijbels, M.J.J. · Dijk, K.W. van · Gorp, P.J.J. van · Suzuki, H. · Kodama, T. · Frants, R.R. · Havekes, L.M. · Hofker, M.H.
Keywords: Biology · Apolipoprotein E · Atherosclerosis · Mouse models · Animals · Aorta, Thoracic · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Diet, Atherogenic · Female · Humans · Male · Membrane Proteins · Mice · Mice, Knockout · Mice, Transgenic · Receptors, Immunologic · Receptors, Lipoprotein · Receptors, Scavenger · Risk Factors · Scavenger Receptors, Class B
[Abstract]

19 Binding of β-VLDL to heparan sulfate proteoglycans requires lipoprotein lipase, whereas apoE only modulates binding affinity
article 1999    
Author: Beer, F. de · Hendriks, W.L. · Vark, L.C. van · Kamerling, S.W.A. · Dijk, K.W. van · Hofker, M.H. · Smelt, A.H.M. · Havekes, L.M.
Keywords: Biology · β-VLDL · apoE · Heparan sulfate proteoglycans · Lipoprotein lipase · Animals · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Binding, Competitive · Cell Line · Cholesterol, VLDL · Heparan Sulfate Proteoglycans · Iodine Radioisotopes · Lipoprotein Lipase · Macrophages · Mice · Mice, Knockout
[Abstract]

20 Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver
article 1999    
Author: Mensenkamp, A.R. · Jong, M.C. · Goor, H. van · Luyn, M.J.A. van · Bloks, V. · Havinga, R. · Voshol, P.J. · Hofker, M.H. · Dijk, K.W. van · Havekes, L.M. · Kuipers, F.
Keywords: Biology · Animals · Apolipoproteins E · Cells, Cultured · Cholesterol · Crosses, Genetic · Fatty Acids, Nonesterified · Glycerol · Homeostasis · Humans · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Knockout · Mice, Transgenic · Microscopy, Immunoelectron · Phytosterols · Sitosterols · Sterols · Triglycerides · Tritium
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 89 found. Next | Sort by date