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1 Urokinase-mediated fibrinolysis in the synovial fluid of rheumatoid arthritis patients may be affected by the inactivation of single chain urokinase type plasminogen activator by thrombin
article 2000    
Author: Braat, E.A.M. · Jie, A.F.H. · Ronday, H.K. · Beekman, B. · Rijken, D.C.
Keywords: Arthritis, Rheumatoid · Fibrinolysis · Humans · Osteoarthritis · Synovial Fluid · Thrombin · Urinary Plasminogen Activator
[Abstract]

2 Quality of life and work in patients with rheumatoid arthritis and ankylosing spondylitis of working age
article 2003    
Author: Chorus, A.M.J. · Miedema, H.S. · Boonen, A. · Linden, S. van der
Keywords: Health · Emotion · Health behavior · Major clinical study · Multiple regression · Rheumatoid arthritis · Scoring system · Social status · Work · Adaptation, Psychological · Adolescent · Adult · Arthritis, Rheumatoid · Employment · Fatigue · Female · Health Status · Humans · Male · Mental Health · Middle Aged · Quality of Life · Questionnaires · Spondylitis, Ankylosing
[Abstract]

3 Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells: Regulation by tumor necrosis factor-α and doxycycline
article 1997    
Author: Hanemaaijer, R. · Sorsa, T. · Konttinen, Y.T. · Ding, Y. · Sutinen, M. · Visser, H. · Hinsbergh, V.W.M. van · Helaakoski, T. · Kainulainen, T. · Rönkä, H. · Tschesche, H. · Salo, T.
Keywords: Arthritis, Rheumatoid · Catalysis · Cells, Cultured · Collagenases · Doxycycline · Endothelium · Endothelium, Vascular · Enzyme Inhibitors · Fibroblasts · Glycosylation · Humans · Matrix Metalloproteinase 8 · RNA, Messenger · Synovial Membrane · Tetradecanoylphorbol Acetate · Tumor Necrosis Factor-alpha · Up-Regulation
[PDF] [Abstract]

4 Increased expression of interferon (IFN)-gamma together with IFN-gamma receptor in the rheumatoid synovial membrane compared with synovium of patients with osteoarthritis
article 1996    
Author: Dolhain, R.J.E.M. · Haar, N.T. ter · Hoefakker, S. · Tak, P.P. · Ley, M. de · Claassen, E. · Breedveld, F.C. · Miltenburg, A.M.M.
Keywords: Health · Interferon-gamma · Interferon-gamma receptor · Osteoarthritis · Rheumatoid arthritis · T-lymphocytes · Antigens, CD · Antigens, CD3 · Arthritis, Rheumatoid · Female · Humans · Hypersensitivity, Delayed · Interferon Type II · Male · Osteoarthritis · Receptors, Interferon · Synovial Membrane · Tonsillitis
[Abstract]

5 Highly increased levels of active stromelysin in rheumatoid synovial fluid determined by a selective fluorogenic assay
article 1997    
Author: Beekman, B. · El, B. van · Drijfhout, J.W. · Ronday, H.K. · TeKoppele, J.M.
Keywords: Biomedical Research · Fluorogenic substrate · MMP-3 · Rheumatoid arthritis · Stromelysin · Synovial fluid · Stromelysin · Controlled study · Enzyme activity · Enzyme assay · Human tissue · Priority journal · Rheumatoid arthritis · Synovial fluid · Technique · Arthritis, Rheumatoid · Biological Assay · Biological Markers · Fluorescence · Humans · Matrix Metalloproteinase 3
[PDF] [Abstract]

6 Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3
article 2003    
Author: Laan, W.H. van der · Quax, P.H.A. · Seemayer, C.A. · Huisman, L.G.M. · Pieterman, E.J. · Grimbergen, J.M. · Verheijen, J.H. · Breedveld, F.C. · Gay, R.E. · Gay, S. · Huizinga, T.W.J. · Pap, T.
Keywords: Adenoviridae · Animals · Arthritis, Rheumatoid · Cartilage, Articular · Cell Division · Fibroblasts · Gene Expression · Gene Therapy · Genetic Vectors · Humans · Matrix Metalloproteinases · Mice · Mice, SCID · Synovial Membrane · Tissue Inhibitor of Metalloproteinase-1 · Tissue Inhibitor of Metalloproteinase-3 · Transduction, Genetic · Adenoviridae · Animalia
[Abstract]

7 Fibroblast-like synoviocyte-chondrocyte interaction in cartilage degradation
article 2007    
Author: Steenvoorden, M.M.C. · Bank, R.A. · Ronday, H.K. · Toes, R.E.M. · Huizinga, T.W.J. · Groot, J. de
Keywords: Health · Biomedical Research · Alginate recovered chondrocytes · Cartilage · Cartilage degradation · Fibroblast-like synoviocytes · In vitro model · Rheumatoid arthritis · Alginates · Animals · Arthritis, Rheumatoid · Cartilage · Cattle · Cell Communication · Cells, Cultured · Chondrocytes · Collagen · Disease Models, Animal · Fibroblasts · Glucuronic Acid · Hexuronic Acids · Interleukin-1beta · Osteoarthritis · Proteoglycans · Synovial Membrane · Tumor Necrosis Factor-alpha
[Abstract]

8 Bone turnover, joint damage and bone mineral density in early rheumatoid arthritis treated with combination therapy including high-dose prednisolone
article 2001    
Author: Verhoeven, A.C. · Boers, M. · Koppele, J.M. te · Laan, W.H. van der · Markusse, H.M.Geusens, P. · Linden, S. van der
Keywords: Health Biology · Biomedical Research · Adult · Aged · Amino Acids · Anti-Inflammatory Agents · Anti-Inflammatory Agents, Non-Steroidal · Antirheumatic Agents · Arthritis, Rheumatoid · Bone Density · Bone Remodeling · Collagen · Cross-Linking Reagents · Drug Therapy, Combination · Female · Humans · Joints · Male · Methotrexate · Middle Aged · Postmenopause · Prednisolone · Regression Analysis · Sulfasalazine · Bone mineral density · Collagen crosslinks · Deoxypyridinoline · Early rheumatoid arthritis · Glucocorticoids · Outcomes · Pyridinoline
[Abstract]

9 Difference in expression of the plasminogen activation system in synovial tissue of patients with rheumatoid arthritis and osteoarthritis
article 1996    
Author: Ronday, H.K. · Smits, H.H. · Muijen, G.N.P. van · Pruszczynski, M.S.M. · Dolhain, R.J.E.M. · Langelaan, E.J. van · Breedveld, F.C. · Verheijen, J.H.
Keywords: Biology · Immunohistochemistry · Osteoarthritis · Plasminogen activation · Rheumatoid arthritis · Urokinase · fibrin · plasminogen activator · plasminogen activator inhibitor · urokinase · article · clinical article · gene expression · human tissue · immunohistochemistry · nonhuman · osteoarthritis · priority journal · rheumatoid arthritis · synovium · Arthritis, Rheumatoid · Enzyme Activation · Humans · Immunohistochemistry · Osteoarthritis · Plasminogen · Plasminogen Activator Inhibitor 1 · Plasminogen Activator Inhibitor 2 · Plasminogen Activators · Receptors, Cell Surface · Synovial Membrane · Tissue Plasminogen Activator · Urinary Plasminogen Activator
[Abstract]

10 Labour force participation among patients with rheumatoid arthritis
article 2000    
Author: Chorus, A.M.J. · Miedema, H.S. · Wevers, C.J. · Linden, S. van der
Keywords: Workplace · Age · Controlled study · Daily life activity · Disease duration · Major clinical study · Outpatient department · Population · Rheumatoid arthritis · Sex · Worker · Activities of Daily Living · Adolescent · Adult · Arthritis, Rheumatoid · Data Collection · Employment · Female · Humans · Male · Middle Aged · Netherlands · Occupational Diseases · Quality of Life · Questionnaires · Beroepsrehabilitatie · Reuma · Nederland · Reintegratie · Arbeidsgehandicapten · Gewrichtsziekten · Arthritis · Arbeid door chronisch zieken · Arbeidsongeschiktheid
[Abstract]

11 What really matters: An inquiry into the relative importance of dimensions of informal caregiver burden
article 2004    
Author: Exel, N.J.A. van · Brouwer, W.B.F. · Berg, B. van den · Koopmanschap, M.A. · Bos, G.A.M. van den
Keywords: Health · Adult · Aged · Body burden · Caregiver · Cerebrovascular accident · Clinical study · Controlled study · Functional assessment · Health status · Major clinical study · Netherlands · Patient care · Quality of life · Rating scale · Rheumatoid arthritis · Scoring system · Self concept · Statistical significance · Task performance · Arthritis, Rheumatoid · Caregivers · Cerebrovascular Accident · Cost of Illness · Cross-Sectional Studies · Female · Humans · Male · Middle Aged · Stress, Psychological
[Abstract]

12 Genetic risk factors for autoimmune diseases
article 1999    
Author: Feltkamp, T.E.W. · Aarden, L.A. · Lucas, C.J. · Verweij, C.L. · Vries, R.R.P. de
Keywords: Biology · Animals · Apoptosis · Arthritis, Experimental · Arthritis, Rheumatoid · Autoimmune Diseases · Celiac Disease · Diabetes Mellitus, Type 1 · Genetic Predisposition to Disease · Humans · Interleukin-10 · Mice · Mice, Inbred MRL lpr · Mice, Knockout · Multiple Sclerosis · Risk Factors · Transforming Growth Factor beta · Tumor Necrosis Factor-alpha
[Abstract]

13 Work factors and behavioural coping in relation to withdrawal from the labour force in patients with rheumatoid arthritis
article 2001    
Author: Chorus, A.M.J. · Miedema, H.S. · Wevers, C.W.J. · Linden, S. van der
Keywords: Workplace · Calculation · Clinical trial · Controlled clinical trial · Controlled study · Coping behavior · Major clinical study · Questionnaire · Randomized controlled trial · Regression analysis · Rheumatoid arthritis · Risk factor · Work · Adaptation, Psychological · Adult · Arthritis, Rheumatoid · Career Mobility · Confidence Intervals · Cross-Sectional Studies · Education, Continuing · Educational Status · Employment · Female · Humans · Interpersonal Relations · Logistic Models · Male · Middle Aged · Odds Ratio · Sex Factors · Work Schedule Tolerance
[Abstract]

14 RAGE activation induces invasiveness of RA fibroblast-like synoviocytes in vitro
article 2007    
Author: Steenvoorden, M.M.C. · Toes, R.E.M. · Ronday, H.K. · Huizinga, T.W.J. · Groot, J. de
Keywords: Biomedical Research · Fibroblast-like synoviocyte · HMGB-1 · Invasiveness · RAGE · Rheumatoid arthritis · advanced glycation end product · advanced glycation end product receptor · chemoattractant · glycosylated albumin · high mobility group B1 protein · ligand · matrigel · protein antibody · article · cell activation · cell function · cell invasion · controlled study · culture medium · fibroblast · human · human cell · in vitro study · joint prosthesis · priority journal · rheumatoid arthritis · serum · synovial fluid · synoviocyte · synovium · Antibodies, Anti-Idiotypic · Arthritis, Rheumatoid · Cell Movement · Cells, Cultured · Glycosylation End Products, Advanced · HMGB1 Protein · Humans · Receptors, Immunologic · Synovial Membrane
[Abstract]

15 Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: The role of advanced glycation end products
article 2001    
Author: Groot, J. de · Verzijl, N. · Wenting-Van Wijk, M.J.G. · Bank, R.A. · Lafeber, F.P.J.G. · Bijlsma, J.W.J. · Tekoppele, J.M.
Keywords: Health Biology · Biomedical Research · glycosaminoglycan · matrix metalloproteinase · pentosidine · adult · aged · article · articular cartilage · cartilage degeneration · clinical article · colorimetry · controlled study · disease course · female · high performance liquid chromatography · human · male · osteoarthritis · priority journal · protein degradation · rheumatoid arthritis · synovial fluid · Adult · Aged · Aged, 80 and over · Aging · Animals · Arginine · Arthritis, Rheumatoid · Cartilage, Articular · Cattle · Chromatography, High Pressure Liquid · Glycosaminoglycans · Humans · Knee Joint · Lysine · Matrix Metalloproteinases · Middle Aged · Osteoarthritis, Knee · Phenylmercuric Acetate · Ribose · Synovial Fluid
[Abstract]

16 Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis
article 2001    
Author: Ronday, H.K. · Laan, W.H. van der · Tak, P.P. · Roos, J.A.D.M. de · Bank, R.A. · Tekoppele, J.M. · Froelich, C.J. · Hack, C.E. · Hogendoorn, P.C.W. · Breedveld, F.C. · Verheijen, J.H.
Keywords: Biology Health · Biomedical Research · Cartilage destruction · Granzyme B · Rheumatoid arthritis · collagen · glycosaminoglycan · granzyme B · hydroxyproline · proline · proteoglycan · sulfate · sulfur 35 · tritium · animal tissue · bone erosion · cartilage degeneration · cartilage matrix · collagen degradation · controlled study · explant · human cell · immunohistochemistry · isotope labeling · joint destruction · nonhuman · priority journal · protein denaturation · protein expression · proteoglycan synthesis · rheumatoid arthritis · synovium · Animals · Arthritis, Rheumatoid · Cartilage · Cattle · Cells, Cultured · Chondrocytes · Collagen · Extracellular Matrix · Granzymes · Humans · Metacarpophalangeal Joint · Proteoglycans · Serine Endopeptidases · Synovial Membrane
[Abstract]

17 Prophylactic and therapeutic effects of a humanized monoclonal antibody against the IL-2 receptor (DACLIZUMAB) on collagen-induced arthritis (CIA) in rhesus monkeys
article 2001    
Author: Brok, H.P.M. · Tekoppele, J.M. · Hakimi, J. · Kerwin, J.A. · Nijenhuist, E.M. · Groot, C.W.de · Bontrop, R.E. · Hart 't, B.A.
Keywords: Biology · Biomedical Research · Animal model · Inflammation · Joint destruction · Nonhuman primate · Rheumatoid arthritis · Collagen · Interleukin 2 receptor · Interleukin 2 receptor antibody · Monoclonal antibody · Animal experiment · Animal model · Autoimmune disease · Controlled study · Drug blood level · Drug half life · Immunization · Immunogenicity · Inflammation · Joint destruction · Male · Nonhuman · Priority journal · Prophylaxis · Rhesus monkey · Rheumatoid arthritis · Animals · Antibodies, Monoclonal · Antibody Specificity · Arthritis, Rheumatoid · Autoantibodies · Autoimmune Diseases · C-Reactive Protein · Collagen · Disease Models, Animal · Drug Evaluation, Preclinical · Humans · Hydroxyproline · Immunization · Immunoglobulin G · Macaca mulatta · Male · Receptors, Interleukin-2 · Weight Loss
[Abstract]

18 Profiling of endogenous peptides in human synovial fluid by NanoLC-MS : Method validation and peptide identification
article 2007    
Author: Kamphorst, J.J. · Heijden, R. van der · Groot, J. de · Lafeber, F.P.J.G. · Reijmers, T.H. · El, B. van · Tjaden, U.R. · Greef, J. van der · Hankemeier, T.
Keywords: Biology · Biomedical Research · Biomarker · High-resolution MS · NanoLC-MS · Orbitrap · Osteoarthritis · Peptide profiling · Peptidomics · Synovial fluid · amyloid A protein · collagen type 2 · hyaluronic acid · proteoglycan · tubulin · vimentin · article · clinical article · controlled study · human · liquid chromatography · mass spectrometry · nucleotide sequence · osteoarthritis · peptide analysis · priority journal · solid phase extraction · synovial fluid · ultrafiltration · validation study · Amino Acid Sequence · Arthritis, Rheumatoid · Biological Markers · Chromatography, Liquid · Gene Expression Profiling · Humans · Mass Spectrometry · Molecular Sequence Data · Osteoarthritis · Peptides · Proteins · Proteomics · Reproducibility of Results · Synovial Fluid
[Abstract]

19 Tranexamic acid, an inhibitor of plasminogen activation, reduces urinary collagen cross-link excretion in both experimental and rheumatoid arthritis
article 1998    
Author: Ronday, H.K. · TeKoppele, J.M. · Greenwald, R.A. · Moak, S.A. · Roos, J.A.D.M. de · Dijkmans, B.A.C. · Breedveld, F.C. · Verheijen, J.H.
Keywords: Health · Biomedical Research · Collagen cross-links · Plasminogen activation system · Tranexamic acid · Collagen · Deoxypyridinoline · Plasminogen · Pyridinoline · Tranexamic acid · Adjuvant arthritis · Animal experiment · Clinical trial · Controlled study · High performance liquid chromatography · Human · Joint destruction · Male · Nonhuman · Oral drug administration · Priority journal · Rat · Rheumatoid arthritis · Urinary excretion · Amino Acids · Animals · Antifibrinolytic Agents · Arthritis · Arthritis, Rheumatoid · Biological Markers · Collagen · Humans · Male · Rats · Rats, Inbred Lew · Time Factors · Tranexamic Acid
[Abstract]

20 Matrix metalloproteinases-3, -8, -9 as markers of disease activity and joint damage progression in early rheumatoid arthritis
article 2003    
Author: Tchetverikov, I. · Lard, L.R. · Groot, J. de · Verzijl, N. · TeKoppele, J.M. · Breedveld, F.C. · Huizinga, T.W.J. · Hanemaaijer, R.
Keywords: Biology · Biomedical Research · gelatinase B · neutrophil collagenase · stromelysin · aged · arthropathy · disease activity · disease course · disease marker · enzyme activity · enzyme blood level · enzyme linked immunosorbent assay · female · human · joint destruction · longitudinal study · major clinical study · male · prediction · rheumatoid arthritis · Adult · alpha-Macroglobulins · Arthritis, Rheumatoid · Biological Markers · C-Reactive Protein · Disease Progression · Female · Humans · Joints · Male · Matrix Metalloproteinase 3 · Matrix Metalloproteinase 9 · Matrix Metalloproteinases · Middle Aged · Prospective Studies · Statistics, Nonparametric
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 25 found. Next | Sort by date