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1 Bile acids exert negative feedback control on bile acid synthesis in cultured pig hepatocytes by suppression of cholesterol 7α-hydroxylase activity
article 1990    
Author: Kwekkeboom, J. · Princen, H.M.G. · Voorthuizen, E.M. van · Kempen, H.J.M.
Keywords: Biology · Animal · Bile Acids and Salts · Cells, Cultured · Cholesterol 7-alpha-Hydroxylase · Feedback · Hydroxycholesterols · Liver · Swine · Taurocholic Acid
[Abstract]

2 Maintenance of bile acid synthesis and cholesterol 7α-hydroxylase activity in cultured rat hepatocytes
article 1990    
Author: Princen, H.M.G. · Meijer, P.
Keywords: Health · Animal · Bile Acids and Salts · Cells, Cultured · Cholesterol 7-alpha-Hydroxylase · Culture Media · Liver · Male · Rats · Rats, Inbred Strains · Animalia · Bovinae
[Abstract]

3 Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7α-hydroxylase in cultured rat hepatocytes and in vivo in the rat
article 1999    
Author: Post, S.M. · Paul Zoeteweij, J. · Bos, M.H.A. · Wit, E.C.M. de · Havinga, R. · Kuipers, F. · Princen, H.M.G.
Keywords: Biology · Acetates · Animals · Anticholesteremic Agents · Bile Acids and Salts · Cells, Cultured · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Enzyme Induction · Enzyme Inhibitors · Liver · Male · Rats · Rats, Wistar · RNA, Messenger · Sterol O-Acyltransferase · Sulfonic Acids · Triglycerides
[Abstract]

4 A comparison of the effects of dietary cellulose and fermentable galacto-oligosaccharide, in a rat model of colorectal carcinogenesis : fermentable fibre confers greater protection than non-fermentable fibre in both high and low fat background
article 1999    
Author: Wijnands, M.V.W. · Appel, M.J. · Hollanders, V.M.H. · Woutersen, R.A.
Keywords: Chemistry · 1,2-Dimethylhydrazine · Animals · Bile Acids and Salts · Carcinogens · Cecum · Cellulose · Cocarcinogenesis · Colorectal Neoplasms · Dietary Fats · Dietary Fiber · Fermentation · Galactose · Gastrointestinal Contents · Hydrogen-Ion Concentration · Male · Oligosaccharides · Plant Oils · Rats · Rats, Wistar · Specific Pathogen-Free Organisms
[Abstract]

5 Bile acids and lipids in isolated rat hepatocytes : Content, synthesis, and release, as affected by cholestyramine treatment of the donor rats
article 1982    
Author: Kempen, H.J.M. · Vos-Holstein, P.M. van · Lange, J. de
Keywords: Biology · Bile acid · Radioisotope · Triacylglycerol · Animal cell · Beta muricholic acid · Cell culture · Controlled study · Drug mechanism · In vitro study · Liver cell · Nonhuman · Oral drug administration · Therapy · Animal · Bile Acids and Salts · Cholestyramine · Lipids · Liver · Male · Rats · Rats, Inbred Strains · Triglycerides
[PDF] [Abstract]

6 Cafestol increases serum cholesterol levels in apolipoprotein E*3- leiden transgenic mice by suppression of bile acid synthesis
article 2000    
Author: Post, S.M. · Roos, B.de · Vermeulen, M. · Afman, L. · Jong, M.C. · Dahlmans, V.E.H. · Havekes, L.M. · Stellaard, F. · Katan, M.B. · Princen, H.M.G.
Keywords: Biology · Animals · Apolipoprotein E3 · Apolipoproteins E · Bile Acids and Salts · Cholesterol · Diet · Diterpenes · Feces · Female · Lipid Metabolism · Lipoproteins · Lipoproteins, IDL · Lipoproteins, VLDL · Liver · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Receptors, LDL
[Abstract]

7 Analysis of fecal bile acids and neutral steroids using gas-liquid chromatography
article 1998    
Author: Srikumar, T.S. · Wezendonk, B. · Dokkum, W. van
Keywords: Nutrition · Bile acids · Gas chromatography · Neutral steroids · Bile acid · Oligosaccharide · Steroid · Accuracy · Bile · European union · Feces analysis · Gas liquid chromatography · Human · Human experiment · Methodology · Normal human · Pilot study · Priority journal · Bile Acids and Salts · Cholestanol · Cholesterol · Chromatography, Gas · Feces · Humans · Phytosterols · Sensitivity and Specificity · Sitosterols · Steroids · Stigmasterol
[Abstract]

8 Bile acids and lipids in isolated rat hepatocytes. II. Source of cholesterol used for bile acid formation, estimated by incorporation of tritium from tritiated water, and by the effect of ML-236B
article 1983    
Author: Kempen, H.J. · Vos Van Holstein, M. · Lange, J.de
Keywords: Biology · Bile acid · Cholic acid · Compactin · Ml 236 b · Radioisotope · Tritium oxide · Unclassified drug · Animal cell · Beta muricholic acid · Cholesterol c 14 · Cholesterol h 3 · Cholesterol synthesis · Dihydroxycholanoic acid · In vitro study · Liver cell · Muricholic acid · Nonhuman · Taurocholic acid c 14 · Animal · Bile Acids and Salts · Cholesterol · Cholestyramine · Lipids · Liver · Naphthalenes · Rats · Tritium
[PDF] [Abstract]

9 Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-α-mediated downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase expression
article 2001    
Author: Post, S.M. · Duez, H. · Gervois, P.P. · Staels, B. · Kuipers, F. · Princen, H.M.G.
Keywords: Animals · Antilipemic Agents · Bile Acids and Salts · Cells, Cultured · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Clofibric Acid · Cytochrome P-450 CYP27A1 · Cytochrome P-450 Enzyme System · Down-Regulation · Hepatocytes · Mice · Mice, Knockout · Pyrimidines · Rats · Receptors, Cytoplasmic and Nuclear · RNA, Messenger · Steroid Hydroxylases · Transcription Factors · Transcription, Genetic
[Abstract]

10 Increased fecal bile acid excretion in transgenic mice with elevated expression of human phospholipid transfer protein
article 2003    
Author: Post, S.M. · Crom, R. de · Haperen, R. van · Tol, A. van · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Bile acid · HDL · Mouse · Phospholipid transfer protein · Reverse cholesterol transport · Animals · Bile Acids and Salts · Biological Transport · Carrier Proteins · Cholesterol · Cholesterol, HDL · Feces · Humans · Lipase · Lipoprotein Lipase · Liver · Male · Membrane Proteins · Mice · Mice, Inbred C57BL · Mice, Transgenic · Phospholipid Transfer Proteins · Sterols
[Abstract]

11 Cafestol, the cholesterol-raising factor in boiled coffee, suppresses bile acid synthesis by downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase in rat hepatocytes
article 1997    
Author: Post, S.M. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Animals · Bile Acids and Salts · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Coffee · Cytochrome P-450 CYP27A1 · Cytochrome P-450 Enzyme System · Diterpenes · Enzyme Induction · Heat · Hydroxymethylglutaryl CoA Reductases · Hydroxymethylglutaryl-CoA Synthase · Hypercholesterolemia · Liver · Male · Rats · Rats, Wistar · Receptors, LDL · RNA, Messenger · Steroid Hydroxylases · Terpenes · Transcription, Genetic · Triglycerides
[Abstract]

12 Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase gene transcription
article 1995    
Author: Twisk, J. · Hoekman, M.F.M. · Lehmann, E.M. · Meijer, P. · Mager, W.H. · Princen, H.M.G.
Keywords: Biology · cholesterol 7alpha monooxygenase · insulin · oxygenase · sterol 27 hydroxylase · unclassified drug · animal cell · article · bile acid synthesis · controlled study · down regulation · enzyme activity · gene expression regulation · hormone action · liver cell culture · nonhuman · transcription regulation · Animal · Bile Acids and Salts · Cells, Cultured · Chloramphenicol O-Acetyltransferase · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 Enzyme System · Down-Regulation · Gene Expression Regulation, Enzymologic · Insulin · Liver · Male · Membrane Glycoproteins · Nuclear Proteins · Rats · Rats, Wistar · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Transcription, Genetic · Transfection
[Abstract]

13 Differential effects of 17α-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat
article 1999    
Author: Koopen, N.R. · Post, S.M. · Wolters, H. · Havinga, R. · Stellaard, F. · Boverhof, R. · Kuipers, F. · Princen, H.M.G.
Keywords: Δ-<sup>22</sup>-β-muricholate · Bile · Cholestasis · Cholesterol-7α- hydroxylase · Enterohepatic circulation · Estrogens · Sterol-27-hydroxylase · Wistar rat · Animals · Aryl Hydrocarbon Hydroxylases · Bile Acids and Salts · Chenodeoxycholic Acid · Cholates · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 CYP27A1 · Cytochrome P-450 Enzyme System · Enterohepatic Circulation · Ethinyl Estradiol · Hydrogen-Ion Concentration · Liver · Male · Rats · Rats, Wistar · RNA, Messenger · Steroid 12-alpha-Hydroxylase · Steroid Hydroxylases
[PDF] [Abstract]

14 Differential feedback regulation of cholesterol 7α-hydroxylase mRNA and transcriptional activity by rat bile acids in primary monolayer cultures of rat hepatocytes
article 1993    
Author: Twisk, J. · Lehmann, E.M. · Princen, H.M.G.
Keywords: Health · bile acid · chenodeoxycholic acid · cholesterol 7alpha monooxygenase · deoxycholic acid · glycocholic acid · messenger rna · animal cell · bile acid synthesis · controlled study · culture medium · dose time effect relation · down regulation · enzyme activity · enzyme regulation · feedback system · gene expression regulation · gene repression · genetic transcription · hydrophobicity · kinetics · liver cell · liver cell culture · monolayer culture · negative feedback · nonhuman · transcription regulation · Animal · Base Sequence · Bile Acids and Salts · Cells, Cultured · Chenodeoxycholic Acid · Cholesterol 7-alpha-Hydroxylase · Cholic Acid · Cholic Acids · Feedback · Gene Expression Regulation · Glycocholic Acid · Kinetics · Liver · Male · Molecular Sequence Data · Rats · RNA, Messenger · Support, Non-U.S. Gov't · Taurocholic Acid · Transcription, Genetic
[Abstract]

15 Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes
article 1995    
Author: Twisk, J. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Biology · bile acid · chenodeoxycholic acid · cholesterol 7alpha monooxygenase · cholic acid · deoxycholic acid · lithocholic acid · messenger rna · oxygenase · sterol · taurocholic acid · animal cell · article · bile acid synthesis · cholesterol metabolism · controlled study · enzyme inhibition · gene repression · liver cell culture · nonhuman · priority journal · rat · transcription regulation · Adenosine Triphosphate · Animal · Bile Acids and Salts · Cells, Cultured · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Down-Regulation · Gene Expression Regulation, Enzymologic · Liver · Male · Mitochondria · Oxidoreductases · Rats · Rats, Wistar · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Taurocholic Acid · Transcription, Genetic
[Abstract]

16 Cholesterol 7α-hydroxylase deficiency in mice on an APOE*3-Leiden background increases hepatic ABCA1 mRNA expression and HDL-cholesterol
article 2006    
Author: Post, S.M. · Groenendijk, M. · Hoogt, C.C. van der · Fievet, C. · Luc, G. · Hoekstra, M. · Princen, H.M.G. · Staels, B. · Rensen, P.C.N.
Keywords: Health · Biomedical Research · High-density lipoprotein · ABC transporter A1 · High density lipoprotein cholesterol · Intermediate density lipoprotein · Low density lipoprotein · Messenger RNA · Phosphatidylcholine sterol acyltransferase · Very low density lipoprotein · Bile acid · Phospholipid transfer protein · Phospholipid transfer protein, mouse · Animal experiment · Animal tissue · Bile acid synthesis · Biosynthesis · Catabolism · Cholesterol blood level · Cholesterol metabolism · cholesterol transport · Conhuman · Protein expression · Transgenic mouse · Genetics · Metabolism · Mouse · Mouse mutant · Physiology · Animals · Apolipoprotein E3 · ATP-Binding Cassette Transporters · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol, HDL · Female · Gene Expression Regulation · Gene Expression Regulation, Enzymologic · Humans · Liver · Mice · Mice, Knockout · Mice, Transgenic · Phosphatidylcholine-Sterol O-Acyltransferase · Phospholipid Transfer Proteins · RNA, Messenger
[Abstract]

17 Determinants of postprandial plasma bile acid kinetics in human volunteers
article 2017    
Author: Fiamoncini, J. · Yiorkas, A.M. · Gedrich, K. · Rundle, M. · Alsters, S.I. · Roeselers, G. · Broek, T.J. van den · Clavel, T. · Lagkouvardos, I. · Wopereis, S. · Frost, G. · Ommen, B. van · Blakemore, A.I. · Daniel, H.
Keywords: Biology · Bile acids · Mixed-meal tolerance test · Oral glucose tolerance test · Postprandial · SLCO1A2 · Chenodeoxycholic acid · Cholic acid · Deoxycholic acid · Genomic DNA · Glycine · Glycochenodeoxycholic acid · Glycocholic acid · Glycodeoxycholic acid · Glycoursodeoxycholic acid · Solute carrier organic anion transporter 1A2 · Taurine · Taurochenodeoxycholic acid · Taurocholic acid · Taurodeoxycholic acid · Taurolitocholic acid · Tauroursodeoxycholic acid · Unclassified drug · Ursodeoxycholic acid · Bile acid blood level · Bile acid synthesis · Clinical trial · Diet restriction · Dietary intake · Enterohepatic circulation · Feces microflora · Gene expression · Genome analysis · Kinetics · Liquid chromatography-mass spectrometry · Oral glucose tolerance test · Phenotype · Postprandial state · Quantitative analysis · Sex difference · Weight reduction · Whole exome sequencing · Blood · Controlled study · Physiology · Randomized controlled trial · Bile Acids and Salts · Fasting · Female · Humans · Male · Metabolic Clearance Rate · Middle Aged · Postprandial Period · Weight Loss · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

18 Novel non-systemic inhibitor of ileal apical Na+-dependent bile acid transporter reduces serum cholesterol levels in hamsters and monkeys
article 2006    
Author: Kitayama, K. · Nakai, D. · Kono, K. · Hoop, A.G. van der · Kurata, H. · Wit, E.C. de · Cohen, L.H. · Inaba, T. · Kohama, T.
Keywords: Biology · Apical sodium-dependent bile acid transporter · Cholesterol · Enterohepatic circulation · Hamster · Hypocholesterolemic agent · Monkey · Carbon 14 · Cholesterol · High density lipoprotein cholesterol · Ileum apical bile acid transporter inhibitor · Phospholipid · Piperidine derivative · R 146224 · Taurocholic acid · Triacylglycerol · Tritium · Unclassified drug · Bile acid · Carrier protein · Cotransporter · Organic anion transporter · Quinoline derivative · Sodium · Sodium bile acid cotransporter · Sodium-bile acid cotransporter · Absorption · Animal experiment · Animal tissue · Bile duct fistula · Bile flow · Cholesterol blood level · Cholesterol esterification · Concentration response · Controlled study · Diet · Dose response · Drug mechanism · Embryo · Feeding · Human cell · Hypercholesterolemia · Hypolipemia · Inhibition kinetics · Time · Triacylglycerol blood level · Urinary excretion · Biosynthesis · Blood · Cell line · Drug antagonism · Drug effect · Genetics · In vitro study · Macaca · Metabolism · Physiology · Sprague Dawley rat · Syrian hamster · Animals · Anticholesteremic Agents · Bile Acids and Salts · Cell Line · Cholesterol · Cricetinae · Humans · Ileum · Macaca fascicularis · Male · Membrane Transport Proteins · Mesocricetus · Organic Anion Transporters, Sodium-Dependent · Piperidines · Quinolines · Rats · Rats, Sprague-Dawley · Sodium · Symporters · Taurocholic Acid
[Abstract]

19 Cholesterol 7α-Hydroxylase Deficiency in Mice on an APOE*3-Leiden Background Impairs Very-Low-Density Lipoprotein Production
article 2004    
Author: Post, S.M. · Groenendijk, M. · Solaas, K. · Rensen, P.C.N. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Bile acid biosynthesis · Cholesterol 7α-hydroxylase · SREBP-1 · Bile acid · Cholesterol · Cholesterol 7alpha monooxygenase · Cholesterol ester · Cytochrome P450 isoenzyme · Messenger RNA · Sterol · Sterol regulatory element binding protein 1 · Unclassified drug · Very low density lipoprotein · Vitamin · Acyltransferase · Alpha tocopherol · Apolipoprotein E3 (Leidein) · Dgat1 protein, mouse · Diacylglycerol acyltransferase · Retinol · Animal experiment · Animal model · Animal tissue · Antioxidant activity · Bile acid synthesis · Catalysis · Cholesterol blood level · Cholesterol metabolism · Controlled study · Enzyme deficiency · Feces level · Gene · Gene expression · Hyperlipidemia · Knockout mouse · Lipid diet · Lipid metabolism · Lipogenesis · Lipoprotein synthesis · Nonhuman · Srebf1 gene · Triacylglycerol blood level · Atherogenic diet · Biosynthesis · Blood · Cross breeding · Feces · Genetics · Metabolism · Mouse mutant · Physiology · Acyltransferases · Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Crosses, Genetic · Diacylglycerol O-Acyltransferase · Diet, Atherogenic · Feces · Female · Hyperlipoproteinemia Type III · Ketone Bodies · Lipid Metabolism · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · RNA, Messenger · Sterols · Triglycerides · Vitamin A · Vitamin E
[Abstract]

20 Bile duct proliferation associated with bile salt-induced hypercholeresis in Mdr2 P-glycoprotein-deficient mice
article 2005    
Author: Hulzebos, C.V. · Voshol, P.J. · Wolters, H. · Kruit, J.K. · Ottenhof, R. · Groen, A.K. · Stellaard, F. · Verkade, H.J. · Kuipers, F.
Keywords: Bile flow · Bile formation · Bile salt synthesis · Cholangiocyte · Cholate kinetics · Cholehepatic shunt · beta actin · bile salt · binding protein · carrier protein · chenodeoxycholic acid · cholic acid · deoxycholic acid · glycoprotein P · ileal bile salt binding protein · lithocholic acid · messenger RNA · multidrug resistance protein 2 · multidrug resistance protein 3 · muricholic acid · tauroursodeoxycholic acid · unclassified drug · animal experiment · animal model · animal tissue · bile acid synthesis · cell proliferation · controlled study · dilution · immunohistochemistry · in vivo study · intestine mucosa · intrahepatic bile duct · kinetics · liver parenchyma · male · mouse · nonhuman · nucleotide sequence · protein analysis · protein deficiency · protein expression · upregulation · Western blotting · wild type · Animals · Bile Acids and Salts · Bile Duct Diseases · Bile Ducts · Carrier Proteins · Cell Division · Cholates · Deuterium · Gallbladder · Intestines · Membrane Glycoproteins · Mice · Mice, Mutant Strains · Organic Anion Transporters, Sodium-Dependent · P-Glycoproteins · Phospholipids · RNA, Messenger · Symporters
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 21 found. Next | Sort by date