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1 The ultimate radiochemical nightmare : upon radio-iodination of Botulinum neurotoxin A, the introduced iodine atom itself seems to be fatal for the bioactivity of this macromolecule
article 2015    
Author: Uhm, J.I.M. van · Visser, G.W.M. · Schans, M.J. van der · Geldof, A.A. · Meuleman, E.J.H. · Nieuwenhuijzen, J.A.
Keywords: Botulinum neurotoxin A · Iodine-125 · Monoclonal antibody · PET research · Radio-iodination · Botulinum toxin A · Cetuximab · Cetuximab i 125 · Radiopharmaceutical agent · Unclassified drug · Biological activity · Controlled study · Drug purity · Gel permeation chromatography · High performance liquid chromatography · Human cell · Immunoreactivity · Iodination · Isotope labeling · Luminescence · Radioactivity · Radiochemistry · Reaction time · Thin layer chromatography · Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
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2 Characterisation of botulinum toxins type A and B, by matrix-assisted laser desorption ionisation and electrospray mass spectrometry
article 2002    
Author: Baar, B.L.M. van · Hulst, A.G. · Jong, A.L. de · Wils, E.R.J.
Keywords: Amino acid sequencing · Botulinum toxins · Mass spectrometry · Peptide mapping · Toxins · Amino acids · Bacteria · Desorption · Ionization · Laser applications · Mass spectrometry · Military operations · Proteins · Electrospray · Toxic materials · Botulinum toxin A · Botulinum toxin B · Hemagglutinin · Pepsin A · Trypsin · Amino acid sequence · Analytic method · Article · Bacterial strain · Clostridium botulinum · Data base · Gene sequence · Liquid chromatography · Mass spectrometry · Priority journal · Protein analysis · Sequence alignment · Amino Acid Sequence · Botulinum Toxin Type A · Botulinum Toxins · Molecular Sequence Data · Pepsin A · Sequence Homology, Amino Acid · Spectrometry, Mass, Electrospray Ionization · Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization · Trypsin · Abelmoschus · Bacteria (microorganisms) · Clostridium · Clostridium botulinum
[Abstract]

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