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1 Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals
article 2005    
Author: Stierum, R. · Heijne, W. · Kienhuis, A. · Ommen, B. van · Groten, J.
Keywords: Toxicology Nutrition · Physiological Sciences · In vitro · In vivo · Liver · Toxicogenomics · bromobenzene · butylcresol · chemical compound · curcumin · food additive · gallic acid propyl ester · proteome · tiabendazole · transcriptome · biochemistry · bioinformatics · comparative toxicology · conference paper · disease marker · DNA fingerprinting · gene expression profiling · genetic procedures · genetic toxicology · genomics · in vitro study · in vivo study · laboratory · liver toxicity · metabolomics · molecular biology · nonhuman · prediction · proteomics · rat · technology · toxicological parameters · transcriptomics · Animals · Food Additives · Genomics · Humans · Liver · Toxicology
[Abstract]

2 Intake of butylated hydroxyanisole and butylated hydroxytoluene and stomach cancer risk : results from analyses in the Netherlands : cohort study
article 2000    
Author: Botterweck, A.A.M. · Verhagen, H. · Goldbohm, R.A. · Kleinjans, J. · Brandt, P.A. van den
Keywords: Nutrition · Medicine · Geneeskunde · Pharmacology · Toxicology · Pathology · Butylated hydroxyanisole · Butylated hydroxytoluene · Cohort study · Stomach neoplasms · Butylated hydroxyanisole · Butylcresol · Fat · Oil · Adult · Aged · Cancer risk · Chemical analysis · Cohort analysis · Dietary intake · Female · Food analysis · Food intake · Human · Male · Netherlands · Questionnaire · Statistical analysis · Stomach cancer · Aged · Antioxidants · Butylated Hydroxyanisole · Butylated Hydroxytoluene · Cohort Studies · Diet · Female · Food Additives · Humans · Male · Middle Aged · Netherlands · No-Observed-Adverse-Effect Level · Prospective Studies · Questionnaires · Risk Assessment · Stomach Neoplasms
[Abstract]

3 The application of in vitro data in the derivation of the acceptable daily intake of food additives
article 1999    
Author: Walton, K. · Walker, R. · Sandt, J.J.M. van de · Castell, J.V. · Knapp, A.G.A.A. · Kozianowski, G. · Roberfroid, M. · Schilter, B.
Keywords: Nutrition · Acceptable daily intake · Food additives · In vitro · Metabolism · Toxicodynamics and uncertainty factor · Toxicokinetics · 2 hydroxybiphenyl · Aluminum · Aspartame · Biphenyl · Brilliant blue · Butylcresol · Curcumin · Cyclamate sodium · Cyclohexylamine · Dodecyl gallate · Erythrosine · Ferrocyanide · Food additive · Gallic acid · Gallic acid propyl ester · Nitrate · Nitrite · Tartrazine · Tiabendazole · Dietary intake · Food safety · Human · Nonhuman · Review · Risk assessment · Species difference · Toxicity testing · Toxicokinetics · Animals · Food Additives · Humans · No-Observed-Adverse-Effect Level · Toxicity Tests · Animalia
[Abstract]

4 Effect of butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole on cytochrome P450 forms in cultured human hepatocytes
article 2008    
Author: Price, R.J. · Scott, M.P. · Giddings, A.M. · Walters, D.G. · Stierum, R.H. · Meredith, C. · Lake, B.G.
Keywords: Biology · Physiological Sciences · Butylated hydroxytoluene · Curcumin · CYP induction · Cytochrome P450 (CYP) · Human hepatocytes · Propyl gallate · Thiabendazole · butylcresol · curcumin · cytochrome P450 · cytochrome P450 1A2 · cytochrome P450 2B6 · cytochrome P450 3A4 · ethoxyresorufin deethylase · gallic acid propyl ester · messenger RNA · tiabendazole · adult · aged · article · controlled study · enzyme activity · human · human cell · liver cell · male · Aged · Anthelmintics · Antioxidants · Butylated Hydroxytoluene · Cells, Cultured · Curcumin · Cytochrome P-450 CYP1A1 · Cytochrome P-450 CYP1A2 · Cytochrome P-450 CYP3A · Cytochrome P-450 Enzyme System · Hepatocytes · Humans · Male · Middle Aged · Propyl Gallate · RNA, Messenger · Steroid Hydroxylases · Thiabendazole
[Abstract]

5 Effect of thiabendazole on some rat hepatic xenobiotic metabolising enzymes
article 2004    
Author: Price, R.J. · Scott, M.P. · Walters, D.G. · Stierum, R.H. · Groten, J.P. · Meredith, C. · Lake, B.G.
Keywords: Nutrition · Physiological Sciences · 1-chloro-2,4-dinitrobenzene · BHT · Butylated hydroxytoluene · CDNB · CH · Cumene hydroperoxide · CYP · Cytochrome P450 · DCNB · Enzyme induction · GSH S-transferase · Rat liver · Thiabendazole · Xenobiotic metabolism · apoprotein · butylcresol · cytochrome P450 1A · cytochrome P450 1A1 · cytochrome P450 1A2 · cytochrome P450 2B · cytochrome P450 2B1 · cytochrome P450 2B2 · glutathione transferase · messenger RNA · tiabendazole · animal cell · animal experiment · article · controlled study · dose response · drug megadose · enzyme activation · enzyme activity · enzyme induction · enzyme metabolism · enzyme substrate · liver microsome metabolism · liver mitochondrion · liver weight · male · nonhuman · nucleotide sequence · protein blood level · rat · xenobiotic metabolism · Acyltransferases · Administration, Oral · Animals · Antinematodal Agents · Antioxidants · Butylated Hydroxytoluene · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Glutathione Transferase · Liver · Male · Rats · Rats, Sprague-Dawley · RNA, Messenger · Thiabendazole
[Abstract]

6 Transcriptome analysis provides new insights into liver changes induced in the rat upon dietary administration of the food additives butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole
article 2008    
Author: Stierum, R. · Conesa, A. · Heijne, W. · Ommen, B.v. · Junker, K. · Scott, M.P. · Price, R.J. · Meredith, C. · Lake, B.G. · Groten, J.
Keywords: Nutrition · Toxicology and Applied Pharmacology · Butylated hydroxytoluene · Curcumin · Drug metabolism · Mixtures · p53 · Peroxisome proliferation · Propyl gallate · Rat · Thiabendazole · Toxicogenomics · butylcresol · complementary DNA · curcumin · cyanide · cytochrome P450 · cytochrome P450 2B1 · cytochrome P450 2B2 · cytochrome P450 2C6 · cytochrome p450 3a9 · cytochrome p450 4a3 · enoyl coenzyme A hydratase · enzyme · gallic acid propyl ester · glutathione transferase · growth arrest and DNA damage inducible protein 45 · palmitoyl coenzyme A · phytanoyl coenzyme a dioxygenase · protein kinase C beta · protein p53 · RNA · serum albumin · tiabendazole · transcriptome · animal tissue · article · controlled study · diet · DNA microarray · food poisoning · gene expression · gene expression profiling · liver · male · metabolism · nonhuman · nucleotide sequence · rat · real time polymerase chain reaction · Western blotting · Animals · Aryl Hydrocarbon Hydroxylases · Body Weight · Butylated Hydroxytoluene · Curcumin · Cytochrome P-450 CYP1A2 · Cytochrome P-450 CYP2B1 · Data Interpretation, Statistical · Diet · DNA, Complementary · Food Additives · Gene Expression · Gene Expression Profiling · Glutathione Transferase · Liver · Male · Organ Size · Oxidation-Reduction · Palmitoyl Coenzyme A · Propyl Gallate · Rats · Rats, Sprague-Dawley · Reverse Transcriptase Polymerase Chain Reaction · Steroid Hydroxylases · Thiabendazole · Rattus
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 6 of 6 found. | Sort by date