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1 Ageing and osteoarthritis: A different perspective
article 2003    
Author: Verzijl, N. · Bank, R.A. · TeKoppele, J.M. · Groot, J. de
Keywords: Biology Health · Biomedical Research · Advanced glycation end products · Cartilage · Chondrocyte · Collagen · Osteoarthritis · Articular cartilage · Cartilage degeneration · Cartilage matrix · Diabetes mellitus · Economic aspect · Musculoskeletal disease · Rigidity · Aging · Cartilage, Articular · Glycosylation End Products, Advanced · Humans
[Abstract]

2 Urinary collagen crosslinks to monitor bone and cartilage degradation in collagen-induced arthritis in rhesus monkeys
article 1995    
Author: Koppele, J.M. te · Hart, B.A. 't.
Keywords: Health · Collagen · Animal experiment · Animal model · Arthritis · Article · Bone defect · Bone matrix · Bone turnover · Cartilage degeneration · Inflammation · Nonhuman · Protein cross linking · Protein urine level · Rhesus monkey · Urinary excretion · Healthy for Life · Healthy Living

3 Inhibition of glycosaminoglycan incorporation influences collagen network formation during cartilage matrix production
article 2009    
Author: Bastiaansen-Jenniskens, Y.M. · Koevoet, W. · Jansen, K.M.B. · Verhaar, J.A.N. · Groot, J. de · Vanosch, G.J.V.M.
Keywords: Biology · Biomedical Research · Cartilage matrix · Glycosaminoglycan · Cartilage cell · Cartilage degeneration · Cell culture · Concentration response · Cross linking · Alginates · Animals · Cattle · Chondrocytes · Collagen Type II · Gene Expression · Glucuronic Acid · Glycosaminoglycans · Glycosides · Hexuronic Acids · SOX9 Transcription Factor · Tissue Culture Techniques · Bovinae
[Abstract]

4 Serum and urinary biochemical markers for knee and hip-osteoarthritis: a systematic review applying the consensus BIPED criteria
article 2010    
Author: Spil, W.E. van · Groot, J. de · Lems, W.F. · Oostveen, J.C.M. · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · Biochemical markers · Biomarkers · BIPED classification · Osteoarthritis · bone sialoprotein · cartilage oligomeric matrix protein · chondroitin sulfate · collagen type 1 · collagen type 2 · deoxypyridinoline · hyaluronic acid · keratan sulfate · osteocalcin · pentosidine · pyridinoline · risedronic acid · blood analysis · bone metabolism · cartilage degeneration · collagen synthesis · diagnostic value · disease severity · hip osteoarthritis · knee osteoarthritis · prognosis · synovium · systematic review · treatment response · urinalysis
[Abstract]

5 Similarities and discrepancies in subchondral bone structure in two differently induced canine models of osteoarthritis
article 2010    
Author: Intema, F. · Sniekers, Y.H. · Weinans, H. · Vianen, M.E. · Yocum, S.A. · Zuurmond, A.-M.M. · Groot, J. de · Lafeber, F.P. · Mastbergen, S.C.
Keywords: Biology · Biomedical Research · μCT · Animal models · Architecture · Osteoarthritis · Subchondral bone · carboxy terminal telopeptide · deoxypyridinoline · animal experiment · animal model · animal tissue · anterior cruciate ligament · article · bone plate · bone structure · cartilage degeneration · cartilage injury · controlled study · cortical bone · female · metaphysis · micro-computed tomography · nonhuman · osteoarthritis · osteolysis · tibia · trabecular bone
[Abstract]

6 Cartilage markers and their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis: The Boston Osteoarthritis Knee Study
article 2007    
Author: Hunter, D.J. · Li, J. · LaValley, M. · Bauer, D.C. · Nevitt, M. · Groot, J. de · Poole, R. · Eyre, D. · Guermazi, A. · Gale, D. · Felson, D.T.
Keywords: Biomedical Research · aggrecan · biological marker · carboxy terminal telopeptide · cartilage oligomeric matrix protein · collagenase · epitope · adult · age · aged · article · body mass · cartilage degeneration · case control study · confidence interval · controlled study · female · follow up · gender · human · knee osteoarthritis · logistic regression analysis · longitudinal study · major clinical study · male · nuclear magnetic resonance imaging · observational study · scoring system
[Abstract]

7 Does loading influence the severity of cartilage degeneration in the canine groove-model of OA?
article 2009    
Author: Vos, P. · Intema, F. · El, B. van · Groot, J. de · Bijlsma, J.W.J. · Lafeber, F. · Mastbergen, S.
Keywords: Canine · Cartilage · Groove-model · Loading · Osteoarthritis · DNA · Cartilage degeneration · Enzyme activity · Femur condyle · Histology · Inflammation · Isotope labeling · Knee osteoarthritis · Leg exercise · Loading test · Osteoarthritis · Synovium · Tibia · Animals · Collagen · Disease Progression · Dogs · Physical Conditioning, Animal · Proteoglycans · Severity of Illness Index · Synovial Membrane · Weight-Bearing
[Abstract]

8 Degenerated and healthy cartilage are equally vulnerable to blood-induced damage
article 2008    
Author: Jansen, N.W.D. · Roosendaal, G. · Bijlsma, J.W.J. · Groot, J. de · Theobald, M. · Lafeber, F.P.J.G.
Keywords: Health · Matrix metalloproteinase · Proteoglycan · Aged · Article · Blood · Cartilage cell · Cartilage degeneration · Controlled study · Enzyme activity · Female · Hemarthrosis · Human · Human tissue · Male · Osteoarthritis · Priority journal · Proteoglycan synthesis · Aged · Blood · Cartilage, Articular · Chondrocytes · Female · Hemarthrosis · Humans · Male · Matrix Metalloproteinases · Middle Aged · Osteoarthritis · Proteoglycans · Tissue Culture Techniques · Food and Nutrition · Healthy Living
[Abstract]

9 Degenerated human articular cartilage at autopsy represents preclinical osteoarthritic cartilage : comparison with clinically defined osteoarthritic cartilage
article 1997    
Author: Valburg, A.A. van · Wenting, M.J.G. · Beekman, B. · TeKoppele, J.M. · Lafeber, F.P.G.J. · Bijlsma, J.W.J.
Keywords: Health · Biomedical Research · cartilage · metalloproteinases · osteoarthritis · proteoglycans · metalloproteinase · proteoglycan · adult · aged · article · articular cartilage · autopsy · cartilage degeneration · controlled study · female · histochemistry · histology · human · human tissue · male · osteoarthritis · priority journal · Aged · Aged, 80 and over · Cartilage, Articular · Female · Humans · Knee Joint · Male · Metalloendopeptidases · Middle Aged · Osteoarthritis · Proteoglycans · Synovial Fluid · Synovial Membrane

10 Matrix metalloproteinase activity in equine synovial fluid: Influence of age, osteoarthritis, and osteochondrosis
article 1998    
Author: Brama, P.A.J. · TeKoppele, J.M. · Beekman, B. · Weeren, P.R. van · Barneveld, A.
Keywords: Biology · Biomedical Research · matrix metalloproteinase · age · animal tissue · article · cartilage degeneration · cartilage matrix · controlled study · enzyme activity · horse · metacarpophalangeal joint · nonhuman · osteoarthritis · osteochondrosis · priority journal · synovial fluid · tarsal joint · Age Factors · Animals · Biological Markers · Fluorometry · Horse Diseases · Horses · Metalloendopeptidases · Osteoarthritis · Osteochondritis · Synovial Fluid
[Abstract]

11 Steady progression of osteoarthritic features in the canine groove model
article 2002    
Author: Marijnissen, A.C.A. · Roermund, P.M. van · Verzijl, N. · Tekoppele, J.M. · Bijlsma, J.W.J. · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · Canine model · Cartilage · Osteoarthritis · Proteoglycans · proteoglycan · Animal experiment · Animal model · Bone injury · Cartilage degeneration · Controlled study · Disease course · Femur condyle · Histopathology · In vivo study · Joint degeneration · Joint injury · Joint stability · Knee osteoarthritis · Laboratory test · Loading test · Nonhuman · Proteoglycan synthesis · Surgical technique · Synovitis · Treatment outcome · Animals · Cartilage, Articular · Disease Models, Animal · Dogs · Female · Joints · Osteoarthritis · Proteoglycans · Synovial Membrane · Time Factors
[Abstract]

12 Compositional and metabolic changes in damaged cartilage are peak- stress, stress-rate, and loading-duration dependent
article 1999    
Author: Chen, C.-T. · Burton-Wurster, N. · Lust, G. · Bank, R.A. · Tekoppele, J.M.
Keywords: Biology · Biomedical Research · Biosynthesis · Compression testing · Impact testing · Metabolism · Monoclonal antibodies · Stress analysis · Tissue culture · Articular cartilage · Monoclonal antibody · Proteoglycan · Animal tissue · Articular cartilage · Cartilage degeneration · Cartilage matrix · Collagen degradation · Compression · Controlled study · Explant · Nonhuman · Proteoglycan synthesis · Shear stress · Tissue metabolism · Water content · Weight bearing · Animal · Cartilage · Collagen · Dogs · Fibronectins · Glycosaminoglycans · Immunohistochemistry · Osteoarthritis · Stress, Mechanical · Support, U.S. Gov't, P.H.S. · Time Factors · Water
[Abstract]

13 Collagen-induced arthritis in rhesus monkeys: Evaluation of markers for inflammation and joint degradation
article 1998    
Author: Hart, B.A. 't · Bank, R.A. · Roos, J.A.D.M. de · Brok, H. · Jonker, M. · Theuns, H.M. · Hakimi, J. · Koppele, J.M.Te.
Keywords: Nutrition · Collagen-induced arthritis · Disease markers · Rhesus monkey · C reactive protein · Collagen · Cyclosporin a · Deoxypyridinoline · Pyridinoline · Animal experiment · Animal model · Arthritis · Blood level · Cartilage degeneration · Controlled study · Diagnostic value · Disease activity · Disease course · Disease marker · Disease predisposition · Disease severity · Female · Inflammation · Joint degeneration · Male · Nonhuman · Priority journal · Remission · Rhesus monkey · Urine level · Weight gain · Weight reduction · Amino Acids · Animals · Antirheumatic Agents · Arthritis, Experimental · Biological Markers · C-Reactive Protein · Collagen · Cross-Linking Reagents · Cyclosporine · Female · Joints · Macaca mulatta · Male · Synovial Fluid · Weight Loss
[Abstract]

14 Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: The role of advanced glycation end products
article 2001    
Author: Groot, J. de · Verzijl, N. · Wenting-Van Wijk, M.J.G. · Bank, R.A. · Lafeber, F.P.J.G. · Bijlsma, J.W.J. · Tekoppele, J.M.
Keywords: Health Biology · Biomedical Research · glycosaminoglycan · matrix metalloproteinase · pentosidine · adult · aged · article · articular cartilage · cartilage degeneration · clinical article · colorimetry · controlled study · disease course · female · high performance liquid chromatography · human · male · osteoarthritis · priority journal · protein degradation · rheumatoid arthritis · synovial fluid · Adult · Aged · Aged, 80 and over · Aging · Animals · Arginine · Arthritis, Rheumatoid · Cartilage, Articular · Cattle · Chromatography, High Pressure Liquid · Glycosaminoglycans · Humans · Knee Joint · Lysine · Matrix Metalloproteinases · Middle Aged · Osteoarthritis, Knee · Phenylmercuric Acetate · Ribose · Synovial Fluid
[Abstract]

15 Putative role of lysyl hydroxylation and pyridinoline cross-linking during adolescence in the occurrence of osteoarthritis at old age
article 2002    
Author: Bank, R.A. · Verzijl, N. · Lafeber, F.P.J.G. · Tekoppele, J.M.
Keywords: Health Biology · Biomedical Research · Collagen · Fatigue · Hydroxylysine · Osteoarthritis · Pyridinoline · collagen · hydroxylysine · pentosidine · pyridinoline · adolescence · adult · aged · article · articular cartilage · cartilage degeneration · clinical article · collagen synthesis · controlled study · cross linking · fatigue · femur condyle · human · human tissue · hydroxylation · knee osteoarthritis · onset age · pathogenesis · priority journal · senescence · stress · stress strain relationship · Aged · Aged, 80 and over · Amino Acids · Arginine · Case-Control Studies · Collagen · Cross-Linking Reagents · Humans · Hydroxylysine · Lysine · Middle Aged · Osteoarthritis, Knee
[Abstract]

16 Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis
article 2001    
Author: Ronday, H.K. · Laan, W.H. van der · Tak, P.P. · Roos, J.A.D.M. de · Bank, R.A. · Tekoppele, J.M. · Froelich, C.J. · Hack, C.E. · Hogendoorn, P.C.W. · Breedveld, F.C. · Verheijen, J.H.
Keywords: Biology Health · Biomedical Research · Cartilage destruction · Granzyme B · Rheumatoid arthritis · collagen · glycosaminoglycan · granzyme B · hydroxyproline · proline · proteoglycan · sulfate · sulfur 35 · tritium · animal tissue · bone erosion · cartilage degeneration · cartilage matrix · collagen degradation · controlled study · explant · human cell · immunohistochemistry · isotope labeling · joint destruction · nonhuman · priority journal · protein denaturation · protein expression · proteoglycan synthesis · rheumatoid arthritis · synovium · Animals · Arthritis, Rheumatoid · Cartilage · Cattle · Cells, Cultured · Chondrocytes · Collagen · Extracellular Matrix · Granzymes · Humans · Metacarpophalangeal Joint · Proteoglycans · Serine Endopeptidases · Synovial Membrane
[Abstract]

17 Urinary pentosidine does not predict cartilage loss among subjects with symptomatic knee OA : the BOKS Study
article 2007    
Author: Hunter, D.J. · LaValley, M. · Li, J. · Zhang, Y. · Bauer, D. · Nevitt, M. · Guermazi, A. · Groot, J. de · Sakkee, N. · Gale, D. · Felson, D.T.
Keywords: Biology · Biomedical Research · Cartilage loss · Knee osteoarthritis · MRI · Pentosidine · creatinine · pentosidine · adult · age · aged · article · articular cartilage · body mass · cartilage degeneration · controlled study · disease severity · female · human · logistic regression analysis · longitudinal study · major clinical study · male · nuclear magnetic resonance imaging · observational study · osteoarthritis · priority journal · risk factor · scoring system · sex difference · synovial fluid level · urine level · Aged · Arginine · Biological Markers · Cartilage · Female · Humans · Logistic Models · Lysine · Magnetic Resonance Imaging · Male · Middle Aged · Osteoarthritis, Knee · Predictive Value of Tests · Prospective Studies
[Abstract]

18 Defects in articular cartilage metabolism and early arthritis in fibroblast growth factor receptor 3 deficient mice
article 2006    
Author: Valverde-Franco, G. · Binette, J.S. · Li, W. · Wang, H. · Chai, S. · Laflamme, F. · Tran-Khanh, N. · Quenneville, E. · Meijers, T. · Poole, A.R. · Mort, J.S. · Buschmann, M.D. · Henderson, J.E.
Keywords: Collagenase 3 · Core protein · Epitope · Fibroblast growth factor receptor 3 · Proteoglycan · Animal cell · Animal experiment · Animal model · Animal tissue · Cartilage degeneration · Cartilage matrix · Cell structure · Compression · Controlled study · Genetic procedures · Humerus head · Hypertrophy · Immunoreactivity · Mouse · Nonhuman · Physical resistance · Protein deficiency · Protein degradation · Protein expression · Protein targeting · Rigidity · Signal transduction · Synovium · Tissue metabolism · Aggrecans · Animals · Arthritis · Cartilage · Cartilage Diseases · Cartilage, Articular · Chondrocytes · Collagen Type II · Collagen Type X · Collagenases · Crosses, Genetic · Epitopes · Extracellular Matrix Proteins · Lectins, C-Type · Matrix Metalloproteinase 13 · Mice · Mice, Transgenic · Osteoblasts · Proteochondroitin Sulfates · Receptor, Fibroblast Growth Factor, Type 3 · Signal Transduction
[Abstract]

19 Monounsaturated and Saturated, but Not n-6 Polyunsaturated Fatty Acids Decrease Cartilage Destruction under Inflammatory Conditions: A Preliminary Study
article 2013    
Author: Bastiaansen-Jenniskens, Y.M. · Siawash, M. · Lest, C.H.A. van de · Verhaar, J.A.N. · Kloppenburg, M. · Zuurmond, A.M. · Stojanovic-Susulic, V. · Osch, G.J.V.M. van · Clockaerts, S.
Keywords: Health · Cartilage · Chondrocyte · Fatty acids · Collagenase 3 · Disintegrin · Glyceraldehyde 3 phosphate dehydrogenase · Glycosaminoglycan · Interstitial collagenase · Lactate dehydrogenase · Linoleic acid · Monounsaturated fatty acid · Oleic acid · Palmitic acid · Polyunsaturated fatty acid · Prostaglandin E2 · Prostaglandin synthase · Saturated fatty acid · Tumor necrosis factor alpha · Adult · Aged · Cartilage cell · Cartilage degeneration · Cell viability · Controlled study · Cytotoxicity · Enzyme release · Gene expression · Human · Human cell · Human tissue · Immunoassay · Inflammation · Limit of quantitation · Lipid transport · Reverse transcription polymerase chain reaction · Total knee replacement · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

20 A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis
article 2002    
Author: Huebner, J.L. · Hanes, M.A. · Beekman, B. · TeKoppele, J.M. · Kraus, V.B.
Keywords: Health Biology · Biomedical Research · Bone and cartilage metabolism · Guinea-pig · Biological marker · Collagen · Deoxypyridinoline · Proteoglycan · Pyridinoline · Animal experiment · Animal model · Animal tissue · Bone metabolism · Cartilage · Cartilage degeneration · Clinical feature · Controlled study · Correlation analysis · Cross linking · Disease course · Disease predisposition · Disease severity · Histopathology · Knee osteoarthritis · Nonhuman · Ossification · Osteolysis · Pathogenesis · Pilot study · Protein metabolism · Strain difference · Synovial fluid · Thickness · Tissue metabolism · Urinary excretion · Amino Acids · Animals · Bone and Bones · Bone Density · Cartilage, Articular · Guinea Pigs · Hindlimb · Joints · Keratan Sulfate · Male · Microscopy, Electron · Osteoarthritis · Osteocalcin · Pilot Projects · Synovial Fluid
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 21 found. Next | Sort by date