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1 Clearance capacity of rat liver Kupffer, endothelial, and parenchymal cells
article 1981    
Author: Praaning-van Dalen, D.P. · Brouwer, A. · Knook, D.L.
Keywords: Albumins · Animal · Antimony · Endothelium · Endotoxins · Heparin · Kupffer Cells · Liver · Metabolic Clearance Rate · Povidone · Rats · Reticuloendothelial System · Tissue Distribution
[Abstract]

2 Radar Mapping of Building Structures Applying Sparse Reconstruction
article 2012    
Author: Tan, R.G. · Wit, J.J.M. de · Rossum, W.L. van
Keywords: Radar · Through-the-wall Radar · Mapping · Buildings · Clearance · Eviction · Security · Safety · Safety and Security · Defence, Safety and Security · Physics & Electronics · RT - Radar Technology · TS - Technical Sciences
[PDF] [Abstract]

3 On the in vivo and in vitro interaction of tissue-type plasminogen activator with liver cells
article 1993    
Author: Otter, M.
Keywords: Biology · Tissue plasminogen activator · Animal cell · Animal experiment · Animal tissue · Drug blood level · Drug clearance · Drug receptor binding · Fibrinolysis · Liver cell · Nonhuman · Note · Rat
[Abstract]

4 Plasma clearance of urokinase-type plasminogen activator
article 1998    
Author: Kaaden, M.E. van der · Rijken, D.C. · Berkel, T.J.C. van · Kuiper, J.
Keywords: Health · urokinase receptor · blood clot lysis · drug receptor binding · endothelium cell · extracellular matrix · glycosylation · internalization · liver metabolism · nonhuman · plasma clearance · plasminogen activation · priority journal · protein isolation · review

5 Modeling the in vitro intrinsic clearance of the slowly metabolized compound tolbutamide determined in sandwich-cultured rat hepatocytes
article 2004    
Author: Treijtel, N. · Barendregt, A. · Freidig, A.P. · Blaauboer, B.J. · Eijkeren, J.C.H. van
Keywords: Biology · Physiological Sciences · 4 tolylsulfonylurea · carboxytolbutamide · hydroxytolbutamide · sulfonylurea derivative · tolbutamide · unclassified drug · addition reaction · animal cell · article · cell culture · controlled study · drug blood level · drug clearance · in vitro study · in vivo study · liquid chromatography · liver cell · mass spectrometry · mathematical model · nonhuman · priority journal · radiochemistry · rat · Animals · Cells, Cultured · Hepatocytes · Male · Metabolic Clearance Rate · Models, Biological · Rats · Rats, Wistar · Tolbutamide · Animalia
[Abstract]

6 Interaction of mutants of tissue-type plasminogen activator with liver cells: Effect of domain deletions
article 1996    
Author: Kuiper, J. · Hof, A. van 't · Otter, M. · Biessen, E.A.L. · Rijken, D.C. · Berkel, T.J.C. van
Keywords: Biology · tissue plasminogen activator · animal cell · animal experiment · article · controlled study · deletion mutant · drug clearance · drug structure · gene cassette · kringle domain · liver cell · male · molecular interaction · nonhuman · plasma clearance · priority journal · protein domain · rat · Animals · Binding Sites · Biological Transport, Active · Endothelium · Epidermal Growth Factor · Half-Life · Kringles · Liver · Male · Molecular Structure · Mutation · Rats · Rats, Wistar · Tissue Plasminogen Activator · Animalia
[Abstract]

7 Pharmacokinetics of carboplatin with and without amifostine in patients with solid tumors
article 1997    
Author: Korst, A.E.C. · Sterre, M.L.T. van der · Eeltink, C.M. · Fichtinger-Schepman, A.M.J. · Vermorken, J.B. · Vijgh, W.J.F. van der
Keywords: Pharmacology · Amifostine · Carboplatin · Adult · Blood sampling · Clinical article · Clinical trial · Controlled clinical trial · Creatinine blood level · Creatinine clearance · Drug blood level · Drug efficacy · Drug half life · Enzyme linked immunosorbent assay · Female · Human · Intravenous drug administration · Male · Phase 1 clinical trial · Solid tumor · Amifostine · Animals · Antineoplastic Agents · Carboplatin · Dose-Response Relationship, Drug · Half-Life · Kidney · Kidney Function Tests · Metabolic Clearance Rate · Mice · Mice, Nude · Neoplasms
[Abstract]

8 The influence of aging on the metabolism of simultaneously administered hexobarbital enantiomers and antipyrine before and after phenobarbital induction in male rats: A longitudinal study
article 1994    
Author: Groen, K. · Breimer, D.D. · Jansen, E.J. · Bezooijen, C.F.A. van
Keywords: Health · 3 hydroxymethylphenazone · 4 hydroxyphenazone · Norphenazone · Phenazone · Adolescent · Aged · Body weight · Controlled study · Drug blood level · Drug clearance · Drug metabolism · Drug urine level · Enantiomer · Enzyme activity · Enzyme specificity · High performance liquid chromatography · Nonhuman · Survival rate · Aging · Animal · Antipyrine · Cytochrome P-450 Enzyme System · Enzyme Induction · Hexobarbital · Longitudinal Studies · Male · Metabolic Clearance Rate · Phenobarbital · Rats · Rats, Inbred BN · Stereoisomerism
[Abstract]

9 The Hyplip2 locus causes hypertriglyceridemia by decreased clearance of triglycerides
article 2007    
Author: Moen, C.J.A. · Tholens, A.P. · Voshol, P.J. · Haan, W. de · Havekes, L.M. · Gargalovic, P. · Lusis, A.J. · Dyk, K.W. van · Frants, R.R. · Hofker, M.H. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Congenic mice · Lipoprotein clearance · Lipoprotein lipase · Lipoproteins · Triglyceride hydrolysis · Animals · Chylomicrons · Female · Genetic Techniques · Hypertriglyceridemia · Lipase · Lipoprotein Lipase · Lipoproteins · Lipoproteins, VLDL · Mice · Mice, Congenic · Postprandial Period · Triglycerides
[PDF] [Abstract]

10 Evaluating in vitro-in vivo extrapolation of toxicokinetics
article 2018    
Author: Wambaugh, J.F. · Hughes, M.F. · Ring, C.L. · MacMillan, D.K. · Ford, J. · Fennell, T.R. · Black, S.R. · Snyder, R.W. · Sipes, N.S. · Wetmore, B.A. · Westerhout, J. · Setzer, R.W. · Pearce, R.G. · Simmons, J.E. · Thomas, R.S.
Keywords: Biology · Environmental chemicals · IVIVE · Toxicokinetics · Animal experiment · Animal tissue · Clearance · Drug bioavailability · Health hazard · In vitro study · In vivo study · Nonhuman · Plasma · Prediction · Rat · Steady state · Toxicokinetics · Uncertainty · Volume of distribution
[Abstract]

11 Toxicity assessment of aggregated/agglomerated cerium oxide nanoparticles in an in vitro 3D airway model: The influence of mucociliary clearance
article 2014    
Author: Kuper, C.F. · Gröllers-Mulderij, M. · Maarschalkerweerd, T. · Meulendijks, N.M.M. · Reus, A. · Acker, F. van · Zondervan-van den Beuken, E.K. · Wouters, M.E.L. · Bijlsma, S. · Kooter, I.M.
Keywords: Nutrition · Cerium oxide · In vitro 3D human bronchial epithelial model · Mucociliary apparatus · Mucociliary clearance · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

12 Moderate cholecalciferol supplementation depresses intestinal calcium absorption in growing dogs
article 2002    
Author: Tryfonidou, M.A. · Stevenhagen, J.J. · Bemd, G.J.C.M. van den · Oosterlaken-Dijksterhuis, M.A. · Deluca, H.F. · Mol, J.A. · Brom, W.E. van den · Leeuwen, J.P.T.M. van · Hazewinkel, H.A.W.
Keywords: Nutrition · Animals · Calcitriol · Calcium · Calcium Radioisotopes · Calcium, Dietary · Cholecalciferol · Cytochrome P-450 Enzyme System · Dogs · Down-Regulation · Female · Gene Expression Regulation, Enzymologic · Intestinal Absorption · Intestines · Kidney · Male · Metabolic Clearance Rate · Models, Animal · Phosphates · Receptors, Calcitriol · Steroid Hydroxylases · Animalia · Canis familiaris
[Abstract]

13 The role of the low-density lipoprotein receptor-related protein (LRP) in the plasma clearance and liver uptake of recombinant single-chain urokinase-type plasminogen activator in rats
article 1997    
Author: Kaaden, M.E. van der · Rijken, D.C. · Kruijt, J.K. · Berkel, T.J.C. van · Kuiper, J.
Keywords: Animals · Drug Evaluation, Preclinical · Iodine Radioisotopes · Kupffer Cells · LDL-Receptor Related Protein 1 · Liver · Male · Metabolic Clearance Rate · Plasminogen Activators · Rats · Rats, Wistar · Receptors, Immunologic · Receptors, LDL · Recombinant Proteins · Tissue Distribution · Urinary Plasminogen Activator
[Abstract]

14 Pulmonary response of hamsters to fibrous glass. - Clearance and morphology after a single intratracheal instillation
article 1986    
Author: Graft, M. van · Spit, B.J. · Immel, H.R. · Feron, V.J.
Keywords: Glass fiber · Animal experiment · Hamster · Injury · Intoxication · Lung clearance · Nonhuman · Pneumoconiosis · Pneumonia · Respiratory system · Animal · Female · Glass · Granuloma · Half-Life · Hamsters · Lung · Macrophages · Male · Mesocricetus · Microscopy, Electron · Neutrophils · Phagocytosis · Pneumonia · Support, Non-U.S. Gov't
[Abstract]

15 Cytotoxic and adaptive effects in rat nasal epithelium after 3-day and 13-week exposure to low concentrations of formaldehyde vapour
article 1988    
Author: Zwart, A. · Woutersen, R.A. · Wilmer, J.W.G.M. · Spit, B.J. · Feron, V.J.
Keywords: formaldehyde · animal experiment · cytotoxicity · histology · inhalation · nonhuman · nose mucosa · priority journal · rat · Adaptation, Physiological · Animal · Cell Division · Epithelium · Female · Formaldehyde · Male · Microscopy, Electron · Mucociliary Clearance · Nose · Rats · Rats, Inbred Strains · Support, Non-U.S. Gov't · Volatilization
[Abstract]

16 Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice
article 2004    
Author: Bovenschen, N. · Dijk, K.W. van · Havekes, L.M. · Mertens, K. · Vlijmen, B.J.M. van
Keywords: Biology · Biomedical Research · Clearance · Factor VIII · Knockout mice · Low-density lipoprotein receptor-related protein · Very low-density lipoprotein receptor · blood clotting factor 8 · cholesterol · triacylglycerol · very low density lipoprotein receptor · animal experiment · article · catabolism · cholesterol blood level · controlled study · knockout mouse · male · mouse · nonhuman · plasma clearance · priority journal · triacylglycerol blood level · Animals · Factor VIII · Integrases · LDL-Receptor Related Proteins · Mice · Mice, Knockout · Mice, Transgenic · Receptors, LDL
[Abstract]

17 3D gait assessment in young and elderly subjects using foot-worn inertial sensors
article 2010    
Author: Mariani, B. · Hoskovec, C. · Rochat, S. · Büla, C. · Penders, J. · Aminian, K.
Keywords: Electronics · 3D gait analysis · Elderly · Foot clearance · Inertial sensors · Turning · 3D gait analysis · Accuracy and precision · Clinical application · Elderly · Foot clearance · Gait cycles · Gait initiation · Gait parameters · Inertial sensor · Mean ages · Objective evaluation · Optical motion capture · Reference systems · Spatial parameters · Stride length · Test-retest reliability · Turning angles · U-shaped · Wearable systems · Gait analysis · Inertial navigation systems · Sensors · Wearable computers · Three dimensional · accuracy · adult · age distribution · aged · algorithm · article · controlled study · equipment design · foot clearance · foot worn inertial sensor · gait · human · human experiment · kinematics · mathematical computing · motion analysis system · musculoskeletal system examination · performance measurement system · priority journal · process optimization · reproducibility · sensor · signal processing · stride length · stride velocity · system analysis · turning angle · Adult · Aged · Aging · Algorithms · Biomechanics · Female · Foot · Gait · Humans · Imaging, Three-Dimensional · Male · Models, Biological · Optical Devices · Remote Sensing Technology · Reproducibility of Results · Young Adult · High Tech Systems & Materials · Industrial Innovation · Mechatronics, Mechanics & Materials · HOL - Holst · TS - Technical Sciences
[Abstract]

18 Clearance and clearance inhibition of the HIV-1 protease inhibitors ritonavir and saquinavir in sandwich-cultured rat hepatocytes and rat microsomes
article 2009    
Author: Treijtel, N. · Eijkeren, J.C.H.v. · Nijmeijer, S. · Greef de - Sandt, I.C.J. van der · Freidig, A.P.
Keywords: Health · Biomedical Research · HIV-protease inhibitors · Metabolism · P-Glycoprotein · Rat hepatocytes · rat liver microsomes · Sandwich-culture · cyclosporin A · drug metabolite · glycoprotein P · ketoconazole · proteinase inhibitor · ritonavir · saquinavir · testosterone derivative · valspodar · verapamil · animal cell · article · cell culture · controlled study · drug clearance · drug excretion · drug metabolism · drug transport · Human immunodeficiency virus 1 · hydroxylation · intrahepatic bile duct · liver cell · liver metabolism · male · microsome · nonhuman · rat · sandwich culture · Animals · Biological Transport, Active · Cell Culture Techniques · Cell Survival · Cells, Cultured · Cyclosporine · Cyclosporins · Dose-Response Relationship, Drug · Hepatocytes · HIV Protease Inhibitors · Ketoconazole · Male · Metabolic Clearance Rate · Microsomes, Liver · Rats · Rats, Wistar · Ritonavir · Saquinavir · Human immunodeficiency virus 1 · Rattus
[Abstract]

19 P-glycoprotein-deficient mice have proximal tubule dysfunction but are protected against ischemic renal injury
article 2007    
Author: Huls, M. · Kramers, C. · Levtchenko, E.N. · Wilmer, M.J.G. · Dijkman, H.B.P.M. · Kluijtmans, L.A.J. · Hoorn, J.W.A. van der · Russel, F.G.M. · Masereeuw, R.
Keywords: Biology · ABC transporter · Drug transporter · Ischemia-reperfusion · Kidney dysfunction · ABC transporter · adenosine triphosphate · amino acid · calcium · creatinine · glucose · glycoprotein P · lithium · protein · sodium · amino acid urine level · animal model · animal tissue · calcium excretion · controlled study · creatinine clearance · diuresis · electron microscopy · glomerulus filtration rate · glucosuria · kidney blood flow · kidney cortex · kidney injury · kidney ischemia · kidney proximal tubule · kidney tubule necrosis · knockout mouse · oxidative stress · plasma clearance · priority journal · protein expression · protein function · sodium excretion · upregulation · urinary excretion · Amino Acids · Animals · Calcium · Diuresis · Fluorescent Antibody Technique · Glomerular Filtration Rate · Glycosuria · Immunohistochemistry · Ischemia · Kidney Failure, Acute · Kidney Tubules, Proximal · Male · Mice · Mice, Inbred Strains · Mice, Knockout · Mitochondria · P-Glycoprotein · Proteinuria · Renal Circulation · Sodium
[Abstract]

20 Inhibition of mannose receptor-mediated-clearance of tissue-type plasminogen activator (t-PA) by dextran : A new explanation for its antithrombotic effect
article 1997    
Author: Noorman, F. · Barrett-Bergshoeff, M.M. · Bekkers, M. · Emeis, J.J. · Rijken, D.C.
Keywords: Biology · Anticoagulant agent · Dextran · Dextran 40 · Dextran 70 · Low density lipoprotein receptor · Mannose receptor · Tissue plasminogen activator · Animal experiment · Bolus injection · Controlled study · Deep vein thrombosis · Drug infusion · Drug mechanism · Human · Human cell · Macrophage · Male · Monocyte · Nonhuman · Plasma clearance · Priority journal · Protein blood level · Rat · Thrombogenesis · Acetylgalactosamine · Animals · Cells, Cultured · Depression, Chemical · Dextrans · Fibrinolytic Agents · Glucose · Humans · Lectins, C-Type · Macrophages · Male · Mannose · Mannose-Binding Lectins · Metabolic Clearance Rate · Protein Binding · Rats · Rats, Wistar · Receptors, Cell Surface · Receptors, LDL · Recombinant Proteins · Tissue Plasminogen Activator
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 53 found. Next | Sort by date