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1 Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκB-C/EBP-β complex formation
article 2003    
Author: Kleemann, R. · Gervois, P.P. · Verschuren, L. · Staels, B. · Princen, H.M.G. · Kooistra, T.
Keywords: Biology · Animals · Antilipemic Agents · Bezafibrate · C-Reactive Protein · CCAAT-Enhancer-Binding Protein-beta · Cell Nucleus · Clofibric Acid · Down-Regulation · Hepatocytes · Humans · Interleukin-1 · Mice · Mice, Knockout · NF-kappa B · NF-kappa B p50 Subunit · Protein Binding · Receptors, Cytoplasmic and Nuclear · Transcription Factors · Transcription, Genetic · Transfection
[Abstract]

2 Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-α-mediated downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase expression
article 2001    
Author: Post, S.M. · Duez, H. · Gervois, P.P. · Staels, B. · Kuipers, F. · Princen, H.M.G.
Keywords: Animals · Antilipemic Agents · Bile Acids and Salts · Cells, Cultured · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Clofibric Acid · Cytochrome P-450 CYP27A1 · Cytochrome P-450 Enzyme System · Down-Regulation · Hepatocytes · Mice · Mice, Knockout · Pyrimidines · Rats · Receptors, Cytoplasmic and Nuclear · RNA, Messenger · Steroid Hydroxylases · Transcription Factors · Transcription, Genetic
[Abstract]

3 Fibrates suppress fibrinogen gene expression in rodents via activation of the peroxisome proliferator-activated receptor-α
article 1999    
Author: Kockx, M. · Gervois, P.P. · Poulain, P. · Derudas, B. · Peters, J.M. · Gonzalez, F.J. · Princen, H.M.G. · Kooistra, T. · Staels, B.
Keywords: Biology · Antilipemic Agents · Cells, Cultured · Clofibrate · Clofibric Acid · DNA-Binding Proteins · Fibrinogen · Gene Expression Regulation · Kinetics · Liver · Male · Mice · Mice, Knockout · Peroxisome Proliferators · Procetofen · Rats · Rats, Sprague-Dawley · Rats, Wistar · Receptors, Cytoplasmic and Nuclear · RNA, Messenger · Transcription Factors · Transcription, Genetic · Triglycerides
[Abstract]

4 Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes. Role of the peroxisome proliferator-activated receptor-α
article 1998    
Author: Kockx, M. · Princen, H.M.G. · Kooistra, T.
Keywords: Health · Animals · Antilipemic Agents · Apolipoprotein A-I · Cells, Cultured · Clofibrate · Clofibric Acid · Dimerization · Female · Fibrinogen · Gemfibrozil · Gene Expression Regulation · Genes, Reporter · Liver · Macaca fascicularis · Male · Peroxisome Proliferators · Plasminogen Activator Inhibitor 1 · Procetofen · Pyrimidines · Receptors, Cytoplasmic and Nuclear · Receptors, Retinoic Acid · Retinoid X Receptors · Trans-Activation (Genetics) · Transcription Factors · Tretinoin
[Abstract]

5 Modulation of plasma fibrinogen levels by ciprofibrate and gemfibrozil in primary hyperlipidaemia
article 1997    
Author: Maat, M.P.M. de · Knipscheer, H.C. · Kastelein, J.J.P. · Kluft, C.
Keywords: Biology · C reactive protein · Ciprofibrate · Acute phase response · Cardiovascular disease · Clinical trial · Controlled clinical trial · Controlled study · Drug effect · Drug mechanism · Fibrinogen blood level · Genetic polymorphism · Hypercholesterolemia · Major clinical study · Oral drug administration · Randomized controlled trial · Risk factor · Adult · Antilipemic Agents · Clofibric Acid · Female · Fibrinogen · Gemfibrozil · Humans · Hyperlipidemias · Male · Middle Aged
[Abstract]

6 Effects of gemfibrozil and ciprofibrate on plasma levels of tissue-type plasminogen activator, plasminogen activator inhibitor-1 and fibrinogen in hyperlipidaemic patients
article 1997    
Author: Kockx, M. · Maat, M.P.M. de · Knipscheer, H.C. · Kastelein, J.P. · Kluft, C. · Princen, H.M.G. · Kooistra, T.
Keywords: Biology · Antigen · Antilipemic agent · Cholesterol · Ciprofibrate · Fibrinogen · Gemfibrozil · Plasminogen activator inhibitor · Tissue plasminogen activator · Triacylglycerol · Adult · Blood level · Cholesterol blood level · Clinical trial · Controlled clinical trial · Controlled study · Double blind procedure · Drug effect · Enzyme immunoassay · Female · Fibrinogen blood level · Hyperlipidemia · Major clinical study · Male · Priority journal · Triacylglycerol blood level · Aged · Antilipemic Agents · Cholesterol · Clofibric Acid · Double-Blind Method · Female · Fibrinogen · Gemfibrozil · Humans · Hyperlipoproteinemia Type II · Male · Middle Aged · Plasminogen Activator Inhibitor 1 · Smoking · Tissue Plasminogen Activator · Treatment Outcome
[Abstract]

7 Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-β1 gene expression in the rat, Syrian hamster and guinea pig
article 2000    
Author: Lake, B.G. · Rumsby, P.C. · Price, R.J. · Cunninghame, M.E.
Keywords: Hepatic peroxisome proliferation · Replicative DNA synthesis · Species differences · Syrian hamster · Transforming growth factor-β1 · ciprofibrate · messenger RNA · methylclofenapate · peroxisome proliferator · peroxisome proliferator activated receptor · pirinixic acid · somatomedin B receptor · transforming growth factor beta1 · animal model · animal tissue · cell division · controlled study · DNA synthesis · enzyme activity · fatty acid oxidation · liver weight · nonhuman · species difference · Syrian hamster · Animals · Cell Division · Clofenapate · Clofibric Acid · Cricetinae · DNA · Gene Expression · Guinea Pigs · Liver · Male · Mesocricetus · Molecular Structure · Organ Size · Peroxisome Proliferators · Pyrimidines · Rats · Rats, Sprague-Dawley · Receptor, IGF Type 2 · Species Specificity · Transforming Growth Factor beta · Cavia · Cavia porcellus · Cricetinae · Mesocricetus auratus · Rodentia · Sus scrofa · Zea mays
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 7 of 7 found. | Sort by date