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1 The transferability from rat subacute 4-week oral toxicity study to translational research exemplified by two pharmaceutical immunosuppressants and two environmental pollutants with immunomodulating properties
article 2015    
Author: Kemmerling, J. · Fehlert, E. · Kuper, C.F. · Rühl-Fehlert, C. · Stropp, G. · Vogels, J. · Krul, C. · Vohr, H.W.
Keywords: Pharmacology · Azathioprine · Benzo[a]pyrene · Cyclosporine A · Hexachlorobenzene · Immunotoxicology · Test Guideline · Immunotoxicity · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

2 Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models
article 2015    
Author: Schmeits, P.C.J. · Schaap, M.M. · Luijten, M. · Someren, E. van · Boorsma, A. · Loveren, H. van · Peijnenburg, A.A.C.M. · Hendriksen, P.J.M.
Keywords: Biology · C57BL/6 · CTLL-2 · Cyclosporine A · Interspecies comparison · Splenocytes · Interleukin 2 · Messenger RNA · Transcription factor Nrf2 · Animal cell · Animal experiment · Cell cycle regulation · Controlled study · Cytotoxic T lymphocyte · Down regulation · Endoplasmic reticulum stress · HepG2 cell line · Human · Human cell · Immune response · Immunotoxicity · In vitro study · In vivo study · Jurkat cell line · Male · Mouse · Nonhuman · Dpleen cell · T lymphocyte activation · Thymoma cell line · Transcriptomics · Unfolded protein response · Upregulation · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

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