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Showing 1 to 20 of 48 found. Next | Sort by date

1 Lysyl oxidase: New looks on LOX
article 2002    
Author: Bank, R.A. · Hinsbergh, V.W.M. van
Keywords: Animals · Arteriosclerosis · Down-Regulation · Endothelium, Vascular · Humans · Lipoproteins, LDL · Protein-Lysine 6-Oxidase
[Abstract]

2 Inhibition of matrix metalloproteinases by bisphosphonates may in part explain their effects in the treatment of multiple myeloma [6]
article 2000    
Author: Teronen, O. · Laitinen, M. · Salo, T. · Hanemaaijer, R. · Heikkilä, P. · Konttinen, Y.T. · Sorsa, T.
Keywords: Pharmacology · Antineoplastic Agents · Breast Neoplasms · Diphosphonates · Down-Regulation · Enzyme Inhibitors · Female · Humans · Male · Matrix Metalloproteinases · Multiple Myeloma · Neoplasm Metastasis

3 Low-density lipoproteins are degraded in HepG2 cells with low efficiency
article 1993    
Author: Lombardi, P. · Mulder, M. · Wit, E. de · Berkel, T.J.C. van · Frants, R.R. · Havekes, L.M.
Keywords: Low density lipoprotein · Low density lipoprotein receptor · Cell density · Cell fractionation · Comparative study · Density gradient centrifugation · Endosome · Hepatoma cell · Human cell · Internalization · Isotope labeling · Lipoprotein metabolism · Protein degradation · Receptor down regulation · Biological Transport · Cell Aggregation · Cell Line · Cells, Cultured · Down-Regulation · Fibroblasts · Human · Iodine Radioisotopes · Kinetics · Lipoproteins, LDL · Liver · Lysosomes · Receptors, LDL · Support, Non-U.S. Gov't
[Abstract]

4 Moderate cholecalciferol supplementation depresses intestinal calcium absorption in growing dogs
article 2002    
Author: Tryfonidou, M.A. · Stevenhagen, J.J. · Bemd, G.J.C.M. van den · Oosterlaken-Dijksterhuis, M.A. · Deluca, H.F. · Mol, J.A. · Brom, W.E. van den · Leeuwen, J.P.T.M. van · Hazewinkel, H.A.W.
Keywords: Nutrition · Animals · Calcitriol · Calcium · Calcium Radioisotopes · Calcium, Dietary · Cholecalciferol · Cytochrome P-450 Enzyme System · Dogs · Down-Regulation · Female · Gene Expression Regulation, Enzymologic · Intestinal Absorption · Intestines · Kidney · Male · Metabolic Clearance Rate · Models, Animal · Phosphates · Receptors, Calcitriol · Steroid Hydroxylases · Animalia · Canis familiaris
[Abstract]

5 Influence of collagen type II and nucleus pulposus cells on aggregation and differentiation of adipose tissue-derived stem cells
article 2008    
Author: Lu, Z.F. · Zandieh-Doulabi, B. · Wuisman, P.I. · Bank, R.A. · Helder, M.N.
Keywords: Adipose Tissue · Adolescent · Adult · Cartilage · Cell Aggregation · Cell Count · Cell Differentiation · Cell Lineage · Cell Shape · Collagen Type I · Collagen Type II · Down-Regulation · Female · Gels · Humans · Integrin alpha2 · Intervertebral Disk · Male · Middle Aged · Protein Subunits · Stem Cells
[PDF] [Abstract]

6 Adenovirus-mediated transfer of the 39 kD receptor-associated protein increases fibrinolytic capacity
article 2001    
Author: Goedde, M.F. · Grimbergen, J.M. · Toet, K.H. · Sitter, T. · Quax, P.H. · Kooistra, T.
Keywords: Adenoviridae · Carrier Proteins · Cells, Cultured · Culture Media, Conditioned · Down-Regulation · Drug Stability · Epithelial Cells · Fibrinolysis · Gene Transfer Techniques · Genetic Vectors · Glycoproteins · Humans · Immunoblotting · LDL-Receptor Related Protein-Associated Protein · Peritoneum · Peritonitis · Time Factors · Tissue Extracts · Tissue Plasminogen Activator
[Abstract]

7 Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase gene transcription
article 1995    
Author: Twisk, J. · Hoekman, M.F.M. · Lehmann, E.M. · Meijer, P. · Mager, W.H. · Princen, H.M.G.
Keywords: Biology · cholesterol 7alpha monooxygenase · insulin · oxygenase · sterol 27 hydroxylase · unclassified drug · animal cell · article · bile acid synthesis · controlled study · down regulation · enzyme activity · gene expression regulation · hormone action · liver cell culture · nonhuman · transcription regulation · Animal · Bile Acids and Salts · Cells, Cultured · Chloramphenicol O-Acetyltransferase · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 Enzyme System · Down-Regulation · Gene Expression Regulation, Enzymologic · Insulin · Liver · Male · Membrane Glycoproteins · Nuclear Proteins · Rats · Rats, Wistar · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Transcription, Genetic · Transfection
[Abstract]

8 Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis
article 2008    
Author: Dihal, A.A. · Woude, H. van der · Hendriksen, P.J.M. · Charif, H. · Dekker, L.J. · IJsselstijn, L. · Boer, V.C.J. de · Alink, G.M. · Burgers, P.C. · Rietjens, I.M.C.M. · Woutersen, R.A. · Stierum, R.H.
Keywords: Biology · Toxicology and Applied Pharmacology · Biomarker · Colorectal cancer · Quercetin · Transcriptomics · fatty acid · glutathione peroxidase 2 · heat shock protein · mitogen activated protein kinase · peroxisome proliferator activated receptor alpha · quercetin · transcriptome · animal experiment · animal model · article · cancer prevention · cell cycle · colon mucosa · colorectal cancer · controlled study · down regulation · energy metabolism · Fischer 344 rat · gene expression · gene targeting · genetic analysis · glycolysis · lipid degradation · male · nonhuman · nucleotide sequence · priority journal · proteomics · rat · statistical significance · tumor biopsy · Animals · Colon · Colorectal Neoplasms · Diet · Down-Regulation · Fatty Acids · Gene Expression Profiling · Glycolysis · Intestinal Mucosa · Male · Mitochondria · Proteome · Quercetin · Rats · Rats, Inbred F344 · Rattus
[Abstract]

9 Endoplasmic reticulum stress leads to the selective transcriptional downregulation of the glucoamylase gene in Aspergillus niger
article 2004    
Author: Al-Sheikh, H. · Watson, A.J. · Lacey, G.A. · Punt, P.J. · MacKenzie, D.A. · Jeenes, D.J. · Pakula, T. · Penttilä, M. · Alcocer, M.J.C. · Archer, D.B.
Keywords: Biology · Biotechnology · actin · chaperone · dithiothreitol · gamma actin · glucan 1,4 alpha glucosidase · glyceraldehyde 3 phosphate dehydrogenase · protein HacA · unclassified drug · article · Aspergillus niger · bipa gene · down regulation · endoplasmic reticulum · fungal cell · fungal gene · fungal strain · gene expression · gene induction · genetic code · glaa gene · nonhuman · pdiA gene · priority journal · promoter region · protein folding · protein secretion · RNA splicing · RNA stability · stress · transcription regulation · upregulation · Aspergillus niger · Dithiothreitol · Down-Regulation · Endoplasmic Reticulum · Fungal Proteins · Gene Expression Regulation, Enzymologic · Gene Expression Regulation, Fungal · Glucan 1,4-alpha-Glucosidase · HSP70 Heat-Shock Proteins · Oligonucleotides, Antisense · Promoter Regions (Genetics) · Protein Folding · Transcription, Genetic · Aspergillus · Aspergillus niger · Fungi
[Abstract]

10 A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo
article 2009    
Author: Kienhuis, A.S. · Poll, M.C.G. van de · Jong, C.H.C. de · Gottschalk, R. · Herwijnen, M. van · Boorsma, A. · Kleinjans, J.C.S. · Stierum, R.H. · Delft, J.H.M. van
Keywords: Biology · Biomedical Research · Coumarin · Gene expression profiling · Hepatotoxicity · Parallelogram approach · Primary human hepatocytes · Species difference · Toxicogenomics · Coumarin · Adult · Aged · Blood clotting · Concentration response · Controlled study · Disorders of mitochondrial functions · Down regulation · Energy consumption · Female · Gene expression profiling · Genomics · Human · Human cell · Liver cell · Liver toxicity · Male · Species difference · Toxicogenetics · Transcriptomics · Animalia · Rattus
[Abstract]

11 Development of an androgen reporter gene assay (AR-LUX) utilizing a human cell line with an endogenously regulated androgen receptor
article 2001    
Author: Blankvoort, B.M.G. · Groene, E.M. de · Meeteren-Kreikamp, A.P. van · Witkamp, R.F. · Rodenburg, R.J.T. · Aarts, J.M.M.J.G.
Keywords: Nutrition · Aldosterone · Androgen · Androgen receptor · Androstanolone · Bolasterone · Dexamethasone · Epigallocatechin gallate · Estradiol · Forskolin · Luciferase · Progesterone · Retinoic acid · Trenbolone · Vitamin D · Assay · Cancer cell culture · Controlled study · Genetic transcription · Genetic transfection · Human · Human cell · Priority journal · Reliability · Reporter gene · Transcription regulation · Validation process · Aldosterone · Androgens · Breast Neoplasms · Dexamethasone · Down-Regulation · Estradiol · Genes, Regulator · Genes, Reporter · Humans · Luciferases · Metribolone · Receptors, Androgen · Transfection · Tumor Cells, Cultured
[Abstract]

12 IL-4 abrogates the inhibitory effect of IL-10 on the development of experimental allergic encephalomyelitis in SJL mice
article 1997    
Author: Nagelkerken, L. · Blauw, B. · Tielemans, M.
Keywords: Biology · Experimental autoimmune encephalomyelitis · IFN-γ · IL-4 · Immunomodulation · Multiple sclerosis · T(h)1 · T(h)2 · Animals · Antibody Formation · Cell Differentiation · Down-Regulation · Encephalomyelitis, Autoimmune, Experimental · Female · Interleukin-10 · Interleukin-4 · Mice · Mice, Inbred Strains · Myelin Proteolipid Protein · Peptide Fragments · Th2 Cells · Time Factors
[Abstract]

13 Negative Regulation of Human Fibrinogen Gene Expression by Peroxisome Proliferator-activated Receptor α Agonists via Inhibition of CCAAT Box/Enhancer-binding Protein β
article 2001    
Author: Gervois, P. · Vu-Dac, N. · Kleemann, R. · Kockx, M. · Dubois, G. · Laine, B. · Kosykh, V. · Fruchart, J.C. · Kooistra, T. · Staels, B.
Keywords: Western blotting · Blotting, Northern · Blotting, Western · CCAAT-Enhancer-Binding Protein-alpha · Cell Line · Dose-Response Relationship, Drug · Down-Regulation · Fibrinogen · Hepatocytes · Humans · Inflammation · Interleukin-6 · Liver · Mutagenesis, Site-Directed · Nuclear Receptor Coactivator 2 · Peroxisome Proliferators · Plasmids · Precipitin Tests · Promoter Regions (Genetics) · Pyrimidines · Receptors, Cytoplasmic and Nuclear · Transcription Factors · Transcription, Genetic · Transfection · Tumor Cells, Cultured
[PDF] [Abstract]

14 Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-α-mediated downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase expression
article 2001    
Author: Post, S.M. · Duez, H. · Gervois, P.P. · Staels, B. · Kuipers, F. · Princen, H.M.G.
Keywords: Animals · Antilipemic Agents · Bile Acids and Salts · Cells, Cultured · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Clofibric Acid · Cytochrome P-450 CYP27A1 · Cytochrome P-450 Enzyme System · Down-Regulation · Hepatocytes · Mice · Mice, Knockout · Pyrimidines · Rats · Receptors, Cytoplasmic and Nuclear · RNA, Messenger · Steroid Hydroxylases · Transcription Factors · Transcription, Genetic
[Abstract]

15 Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκB-C/EBP-β complex formation
article 2003    
Author: Kleemann, R. · Gervois, P.P. · Verschuren, L. · Staels, B. · Princen, H.M.G. · Kooistra, T.
Keywords: Biology · Animals · Antilipemic Agents · Bezafibrate · C-Reactive Protein · CCAAT-Enhancer-Binding Protein-beta · Cell Nucleus · Clofibric Acid · Down-Regulation · Hepatocytes · Humans · Interleukin-1 · Mice · Mice, Knockout · NF-kappa B · NF-kappa B p50 Subunit · Protein Binding · Receptors, Cytoplasmic and Nuclear · Transcription Factors · Transcription, Genetic · Transfection
[Abstract]

16 Global Suppression of IL-6-induced Acute Phase Response Gene Expression after Chronic in Vivo Treatment with the Peroxisome Proliferator-activated Receptor-α Activator Fenofibrate
article 2004    
Author: Gervois, P. · Kleemann, R. · Pilon, A. · Percevault, F. · Koenig, W. · Staels, B. · Kooistra, T.
Keywords: Biology · Biomedical Research · Biological organs · Enzyme kinetics · Lipids · Metabolism · Patient treatment · Plasmas · Acute phase response (APR) · Gene expression · Genetic engineering · Albumin · Alpha 2 macroglobulin · CCAAT enhancer binding protein · CCAAT enhancer binding protein alpha · CCAAT enhancer binding protein beta · CCAAT enhancer binding protein delta · Fenofibrate · Fibrinogen · Interleukin 6 · peroxisome proliferator activated receptor agonist · peroxisome proliferator activated receptor alpha · serum amyloid A · STAT3 protein · Stress activated protein kinase · Transcription factor · Unclassified drug · Acute phase response · Animal experiment · Animal tissue · Clinical article · Controlled study · Down regulation · Enzyme activation · Fibrinogen blood level · Gene expression regulation · Hyperlipidemia · In vivo study · Knockout mouse · Liver · Long term care · Male · Mouse · Nonhuman · Protein expression · Protein function · Protein phosphorylation · Transcription regulation · Wild type · Acute-Phase Reaction · Animals · Antilipemic Agents · Apolipoproteins · Down-Regulation · Fibrinogen · Haptoglobins · Humans · Interleukin-6 · Mice · Procetofen · Receptors, Cytoplasmic and Nuclear · Serum Amyloid A Protein · Signal Transduction · Transcription Factors · Animalia · Eukaryota
[PDF] [Abstract]

17 Functions of the CCCH type zinc finger protein OsGZF1 in regulation of the seed storage protein GluB-1 from rice
article 2014    
Author: Chen, Y. · Sun, A. · Wang, M. · Zhu, Z. · Ouwerkerk, P.B.F.
Keywords: Biology · CCCH · GluB-1 · Glutelin · Repressor · Rice · Zinc finger · DNA binding protein · GluB 1 protein, Oryza · GluB-1 protein, Oryza · Gluten · Nitrogen · Vegetable protein · Zinc finger protein · Binding site · Cytology · DNA sequence · Down regulation · Gene expression regulation · Gene library · Genetics · Metabolism · Molecular genetics · Nucleotide sequence · Physiology · Plant seed · Promoter region · Reporter gene · Rice · RNA interference · Transgenic plant · Two hybrid system · Base Sequence · Binding Sites · DNA-Binding Proteins · Down-Regulation · Gene Expression Regulation, Plant · Gene Library · Genes, Reporter · Glutens · Molecular Sequence Data · Nitrogen · Oryza sativa · Plant Proteins · Plants, Genetically Modified · Promoter Regions, Genetic · RNA Interference · Seeds · Sequence Analysis, DNA · Two-Hybrid System Techniques · Zinc Fingers · Healthy for Life · Healthy Living Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

18 Comparative transcriptomic and metabolomic analysis of fenofibrate and fish oil treatments in mice
article 2011    
Author: Lu, Y. · Boekschoten, M.V. · Wopereis, S. · Müller, M. · Kersten, S.
Keywords: Biology · Complement and coagulation cascades · Lipid metabolism · Liver · Peroxisome proliferator-activated receptor · amino acid · cholesterol · fenofibrate · fish oil · peroxisome proliferator activated receptor alpha · triacylglycerol · amino acid blood level · animal experiment · arachidonic acid metabolism · article · cardiovascular risk · cholesterol blood level · citric acid cycle · comparative study · controlled study · down regulation · fatty acid metabolism · fatty acid synthesis · gene control · male · metabolomics · mouse · nonhuman · priority journal · transcriptomics · treatment duration · triacylglycerol blood level · upregulation · Healthy Living · Life · MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[Abstract]

19 A combined transcriptomics and lipidomics analysis of subcutaneous, epididymal and mesenteric adipose tissue reveals marked functional differences
article 2010    
Author: Caesar, R. · Manieri, M. · Kelder, T. · Boekschoten, M. · Evelo, C. · Müller, M. · Kooistra, T. · Cinti, S. · Kleemann, R. · Drevon, C.A.
Keywords: Biology · Biomedical Research · Acetyl coenzyme A · Adenosine triphosphate citrate lyase · Androgen receptor · Carbohydrate responsive element binding protein · Fatty acid synthase · Linoleic acid · Linolenic acid · Monounsaturated fatty acid · Omega 3 fatty acid · Omega 6 fatty acid · Transcription factor · Unclassified drug · Abdominal fat · Adipocyte · Animal cell · Animal tissue · Controlled study · Down regulation · Epididymis fat · Fat intake · Fatty acid desaturation · Fatty acid synthesis · Gene expression regulation · Lipid diet · Lipid metabolism · Lipid storage · Lipidomics · Lipogenesis · Male · Microarray analysis · Mouse · Nonhuman · Spermatogenesis · Subcutaneous fat · Transcriptomics
[PDF] [Abstract]

20 Network-based integration of molecular and physiological data elucidates regulatory mechanisms underlying adaptation to high-fat diet
article 2015    
Author: Derous, D. · Kelder, T. · Schothorst, E.M. van · Erk, M. van · Voigt, A. · Klaus, S. · Keijer, J. · Radonjic, M.
Keywords: Adipose tissue · Data integration · High-fat diet · Network analysis · Systems biology · Transcriptional regulation · Transcriptomics · Transforming growth factor beta · Adaptation · Analytic method · Animal tissue · Caloric intake · Cell respiration · Controlled study · Disorders of mitochondrial functions · Down regulation · Epididymis fat · Gene expression · Immune response · Lipid diet · Low fat diet · Male · Metabolic regulation · Mouse · Network analysis · Nonhuman · Organ weight · Signal transduction · Stress · Transcription regulation · White adipose tissue · Murinae · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 48 found. Next | Sort by date