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Showing 1 to 15 of 15 found. | Sort by date

1 The long-term study in rodents for identifying carcinogens: Some controversies and suggestions for improvements
article 1986    
Author: Feron, V.J. · Kroes, R.
Keywords: Animal experiment · Carcinogen testing · Chemical carcinogenesis · Intoxication · Mouse · Nonhuman · Rat · Rodent · Toxicity testing · Animal · Drug Administration Schedule · International Cooperation · Mutagenicity Tests · Rodentia · Zoology · Medicine · Geneeskunde · Pathology
[Abstract]

2 Coadministration of antigen and particles optimally stimulates the immune response in an intranasal administration model in mice
article 2001    
Author: Zijverden, M. van · Haar, C. de · Beelen, A. van · Loveren, H. van · Penninks, A. · Pieters, R.
Keywords: Nutrition · Administration, Intranasal · Animals · Antibody-Producing Cells · Carbon · Cell Count · Disease Models, Animal · Drug Administration Schedule · Enzyme-Linked Immunosorbent Assay · Female · Hypersensitivity · Immunoglobulin E · Immunoglobulin G · Lung · Lymph Nodes · Mice · Mice, Inbred BALB C · Ovalbumin · Particle Size · Time Factors · Animalia
[Abstract]

3 Influence of single and multiple doses of amifostine on the efficacy and the pharmacokinetics of carboplatin in mice
article 1997    
Author: Korst, A.E.C. · Boven, E. · Sterre, M.L.T. van der · Fichtinger-Schepman, A.M.J. · Vijgh, W.J.F. van der
Keywords: Amifostine · Anti-tumour activity · Carboplatin · Hypothermia · Pharmacokinetics · Amifostine · Animals · Antineoplastic Agents · Body Temperature · Carboplatin · DNA Adducts · Drug Administration Schedule · Drug Synergism · Female · Humans · Mice · Mice, Nude · Neoplasm Transplantation · Ovarian Neoplasms · Platinum · Radiation-Protective Agents · Transplantation, Heterologous
[PDF] [Abstract]

4 Effect of variable versus fixed exposure levels on the toxicity of acetaldehyde in rats
article 1986    
Author: Appelman, L.M. · Woutersen, R.A. · Feron, V.J. · Hooftman, R.N. · Notten, W.R.F.
Keywords: Acetaldehyde · Animal experiment · Inhalation · Intoxication · Lung alveolus macrophage · Lung toxicity · Nonhuman · Nose mucosa · Olfactory epithelium · Olfactory system · Phagocytosis · Rat · Respiratory system · Acetaldehyde · Administration, Inhalation · Animal · Drug Administration Schedule · Lung · Male · Nasal Mucosa · Phagocytosis · Rats · Rats, Inbred Strains
[Abstract]

5 Subchronic oral toxicity studies with erythritol in mice and rats
article 1996    
Author: Til, H.P. · Kuper, C.F. · Falke, H.E. · Bär, A.
Keywords: erythritol · animal experiment · article · body weight · chronic toxicity · controlled study · diarrhea · dose response · female · histopathology · male · mouse · nonhuman · priority journal · rat · Administration, Oral · Animals · Body Weight · Dose-Response Relationship, Drug · Drug Administration Schedule · Eating · Edema · Erythritol · Female · Male · Mice · Rats · Rats, Wistar · Stomach Diseases · Sweetening Agents · Urine · Animalia
[Abstract]

6 Salsalate activates brown adipose tissue in mice
article 2015    
Author: Dam, A.D. van · Nahon, K.J. · Kooijman, S. · Berg, S.M. van den · Kanhai, A.A. · Kikuchi, T. · Heemskerk, M.M. · Harmelen,V. van · Lombès, M. · Hoek,A.M. van den · Winther, M.P. de · Lutgens, E. · Guigas, B. · Rensen, P.C. · Boon, M.R.
Keywords: Biology · Salicylic acid derivative · Salsalate · Administration and dosage · Adverse effects · Brown adipose tissue · Drug administration · Drug effects · Fat intake · Metabolism · Mouse · Physiology · Transgenic mouse · Adipose Tissue, Brown · Animals · Dietary Fats · Drug Administration Schedule · Glucose · Lipid Metabolism · Male · Mice · Mice, Transgenic · Obesity · Salicylates · Weight Gain · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

7 Four-week oral toxicity study with erythritol in rats
article 1996    
Author: Til, H.P. · Modderman, J.
Keywords: Toxicology · erythritol · animal experiment · article · body weight · cecum · controlled study · diarrhea · drug toxicity · female · histology · male · nonhuman · organ weight · priority journal · rat · Administration, Oral · Animals · Body Weight · Dose-Response Relationship, Drug · Drinking · Drug Administration Schedule · Eating · Erythritol · Female · Male · Organ Size · Potassium · Rats · Rats, Wistar · Sodium · Sweetening Agents · Animalia · Rattus norvegicus
[Abstract]

8 Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients
article 2002    
Author: Kuenen, B.C. · Levi, M. · Meijers, J.C.M. · Kakkar, A.K. · Hinsbergh, V.W.M. van · Kostense, P.J. · Pinedo, H.M. · Hoekman, K.
Keywords: Angiogenesis Inhibitors · Blood Coagulation · Blood Platelets · Carcinoma, Renal Cell · Cell Division · Cell Membrane Permeability · Cell Movement · Drug Administration Schedule · Endothelium, Vascular · Fibrinolysis · Hemostasis · Indoles · Kidney Neoplasms · Melanoma · Neovascularization, Pathologic · Protein C · Proto-Oncogene Proteins · Pyrroles · Receptor Protein-Tyrosine Kinases · Receptors, Growth Factor · Receptors, Vascular Endothelial Growth Factor · Sarcoma · Thrombin · Vascular Endothelial Growth Factor Receptor-1
[Abstract]

9 Acetyldinaline: A new oral cytostatic drug with impressive differential activity against leukemic cells and normal stem cells - Preclinical studies in a relevant rat model for human acute myelocytic leukemia
article 1993    
Author: El-Beltagi, H.M. · Martens, A.C.M. · Lelieveld, P. · Haroun, E.A. · Hagenbeek, A.
Keywords: Administration, Oral · Animal · Antineoplastic Agents · Bone Marrow · Bone Marrow Cells · Cell Differentiation · Cell Survival · Clone Cells · Comparative Study · Disease Models, Animal · Dose-Response Relationship, Drug · Drug Administration Schedule · Drug Evaluation · Drug Screening Assays, Antitumor · Hematopoietic Stem Cells · Leukemia, Myelocytic, Acute · Male · Phenylenediamines · Rats · Rats, Inbred BN · Support, Non-U.S. Gov't · Tumor Cells, Cultured
[Abstract]

10 Repeated dose oral toxicological evaluation of concentrated barley β-glucan in CD-1 mice including a recovery phase
article 2003    
Author: Delaney, B. · Carlson, T. · Zheng, G.-H. · Hess, R. · Knutson, N. · Frazer, S. · Ostergren, K. · Zijverden, M. van · Knippels, L. · Jonker, D. · Penninks, A.
Keywords: Toxicology Biology · Toxicology and Applied Pharmacology · beta glucan · animal experiment · animal tissue · article · barley · controlled study · evaluation · female · hematological parameters · histopathology · immunoreactivity · lymph node · lymphoid organ · male · mouse · nonhuman · oat · organ weight · toxicity testing · Animal Feed · Animals · Diet · Dietary Fiber · Dose-Response Relationship, Drug · Drug Administration Schedule · Female · Glucans · Hematologic Tests · Hordeum · Lymphoid Tissue · Male · Mice · Mice, Inbred Strains · Toxicity Tests · Animalia · Avena · Hordeum vulgare subsp. vulgare
[Abstract]

11 Lack of effect of doxycycline on disease activity and joint damage in patients with rheumatoid arthritis. A double blind, placebo controlled trial
article 2001    
Author: Laan, W. van der · Molenaar, E. · Ronday, K. · Verheijen, J. · Breedveld, F. · Greenwald, R. · Dijkmans, B. · Tekoppele, J.
Keywords: Health · Biomedical Research · Doxycycline · Pyridinolines · Rheumatoid arthritis · deoxypyridinoline · doxycycline · placebo · pyridinoline · clinical examination · clinical trial · controlled clinical trial · controlled study · crossover procedure · disease activity · double blind procedure · erythrocyte sedimentation rate · foot radiography · hand radiography · joint destruction · joint stiffness · laboratory test · major clinical study · randomized controlled trial · scoring system · Adolescent · Adult · Aged · Aged, 80 and over · Analysis of Variance · Arthritis, Rheumatoid · Chi-Square Distribution · Cross-Over Studies · Dose-Response Relationship, Drug · Double-Blind Method · Doxycycline · Drug Administration Schedule · Female · Follow-Up Studies · Humans · Male · Middle Aged · Pain Measurement · Reference Values · Severity of Illness Index · Treatment Failure · Treatment Outcome
[Abstract]

12 Short-term dexamethasone treatment inhibits vein graft thickening in hypercholesterolemic ApoE3Leiden transgenic mice
article 2006    
Author: Schepers, A. · Pires, N.M.M. · Eefting, D. · Vries, M.R. de · Bokel, J.H. van · Quax, P.H.A.
Keywords: Biology · Biomedical Research · Dexamethasone · Animal experiment · Animal model · Animal tissue · Artery intima proliferation · Carotid artery · Controlled study · Hypercholesterolemia · Mouse · Nonhuman · Protein expression · Short course therapy · Transgenic mouse · Vein graft · Vein graft disease · Vein graft thickening · Animals · Apolipoprotein E3 · Apolipoproteins E · Atherosclerosis · Base Sequence · Dexamethasone · Disease Models, Animal · Drug Administration Schedule · Endothelium, Vascular · Graft Occlusion, Vascular · Graft Rejection · Graft Survival · Humans · Hypercholesterolemia · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Molecular Sequence Data · Reverse Transcriptase Polymerase Chain Reaction · Risk Assessment · RNA, Messenger · Saphenous Vein · Sensitivity and Specificity · Treatment Outcome · Vascular Surgical Procedures
[Abstract]

13 Preexposure to amorphous silica particles attenuates but also enhances allergic reactions in trimellitic anhydride-sensitized brown Norway rats
article 2008    
Author: Arts, J.H.E. · Schijf, M.A. · Kuper, C.F.
Keywords: Biology · Toxicology and Applied Pharmacology · silicon dioxide · trimellitic anhydride · animal experiment · animal model · animal tissue · article · biochemistry · breathing pattern · brown Norway rat · cell infiltration · controlled study · eosinophil · female · histopathology · inflammation · laryngeal inflammation · laryngeal ulceration · larynx disorder · liver weight · lung edema · lung function · lung lavage · lung weight · lymph node · lymphocyte count · macrophage · neutrophil · nonhuman · priority journal · rat · respiratory tract allergy · squamous cell metaplasia · tidal volume · Allergens · Animals · Body Weight · Drug Administration Schedule · Female · Immunoglobulin E · Liver · Lung · Lymph Nodes · Organ Size · Phthalic Anhydrides · Rats · Respiratory Function Tests · Silicon Dioxide · Animalia · Rattus norvegicus
[Abstract]

14 Effect of low dose atorvastatin versus diet-induced cholesterol lowering on atherosclerotic lesion progression and inflammation in apolipoprotein E*3-Leiden transgenic mice
article 2005    
Author: Verschuren, L. · Kleemann, R. · Offerman, E.H. · Szalai, A.J. · Emeis, S.J. · Princen, H.M.G. · Kooistra, T.
Keywords: Biology · Biomedical Research · Growth factors · Lipids · Lipoprotein metabolism · Pathophysiology · C reactive protein · Cholesterol · Gelatinase B · Macrophage migration inhibition factor · Plasminogen activator inhibitor 1 · Vascular cell adhesion molecule 1 · Animal cell · Animal experiment · animal model · Antiinflammatory activity · Aorta arch · Cholesterol blood level · Cholesterol diet · Controlled study · Dietary intake · Disease activity · Disease course · Disease severity · Inflammation · Lipoprotein metabolism · Low drug dose · Macrophage · Monocyte · Mouse · Nonhuman · Pathophysiology · Protein expression · Smooth muscle fiber · Transgenic mouse · Treatment outcome · Amyloid A protein · Apolipoprotein E3 · Atorvastatin · Animals · Anticholesteremic Agents · Aorta · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Biological Markers · C-Reactive Protein · Cholesterol · Diet · Diet, Atherogenic · Drug Administration Schedule · Female · Heptanoic Acids · Inflammation · Male · Mice · Mice, Transgenic · Pyrroles · Serum Amyloid A Protein
[Abstract]

15 Mouse models for atherosclerosis and pharmaceutical modifiers
article 2007    
Author: Zadelaar, A.S.M. · Kleemann, R. · Verschuren, L. · Vries-van der Weij, J. de · Hoorn, J. van der · Princen, H.M. · Kooistra, T.
Keywords: Biology · Biomedical Research · ACE inhibitors · AT1 receptor antagonists · Atherosclerosis · LXR · Mouse models · Pharmaceutical drugs · PPAR · Statins · atorvastatin · avasimibe · candesartan · captopril · cholesterol acyltransferase inhibitor · dipeptidyl carboxypeptidase inhibitor · hydralazine · hydroxymethylglutaryl coenzyme A reductase inhibitor · irbesartan · losartan · ly 465608 · n (2,2,2 trifluoroethyl) n [4 [2,2,2 trifluoro 1 hydroxy 1 (trifluoromethoxy)ethyl]phenyl]benzenesulfonamide · olmesartan · perindopril · peroxisome proliferator activated receptor alpha agonist · pirinixic acid · pitavastatin · pravastatin · quinapril · ramipril · rosuvastatin · simvastatin · telmisartan · temocapril · unindexed drug · valsartan · zofenopril · antihypertensive agent · antilipemic agent · apolipoprotein E · atherosclerosis · pathophysiology · sensitivity and specificity · Animals · Antihypertensive Agents · Antilipemic Agents · Apolipoproteins E · Atherosclerosis · Disease Models, Animal · Dose-Response Relationship, Drug · Drug Administration Schedule · Dyslipidemias · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hypertension · Male · Mice · Mice, Knockout · Mice, Transgenic · Sensitivity and Specificity
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 15 of 15 found. | Sort by date