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1 Glutathione conjugation of the cytostatic drug ifosfamide and the role of human glutathione S-transferases
article 1995    
Author: Dirven, H.A.A.M. · Megens, L. · Oudshoorn, M.J. · Dingemanse, M.A. · Ommen, B. van · Bladeren, P.J. van
Keywords: Nutrition · Glutathione · Glutathione transferase · Ifosfamide · Cancer chemotherapy · Drug conjugation · Drug detoxification · Drug resistance · Enzyme activity · Human · Human tissue · Leukemia · Lymphoma · Solid tumor · Antineoplastic Agents, Alkylating · Biotransformation · Chromatography, High Pressure Liquid · Drug Resistance, Neoplasm · Glutathione · Glutathione Transferase · Human · Ifosfamide · Isoenzymes · Magnetic Resonance Spectroscopy · Metabolic Detoxication, Drug · Spectrometry, Mass, Fast Atom Bombardment · Support, Non-U.S. Gov't
[Abstract]

2 The role of human glutathione S-transferase isoenzymes in the formation of glutathione conjugates of the alkylating cytostatic drug thiotepa
article 1995    
Author: Dirven, H.A.A.M. · Dictus, E.L.J.T. · Broeders, N.L.H.L. · Ommen, B. van · Bladeren, P.J. van
Keywords: Nutrition · Glutathione · Glutathione reductase · Tepa · Thiotepa · Conformational transition · Drug conformation · Drug conjugation · Drug protein binding · Drug resistance · Enzyme activity · Priority journal · Chromatography, High Pressure Liquid · Female · Glutathione · Glutathione Transferase · Human · Isoenzymes · Kinetics · Liver · Magnetic Resonance Spectroscopy · Placenta · Pregnancy · Support, Non-U.S. Gov't · Thiotepa
[Abstract]

3 Use of biosensors for rapid drug residue analysis without sample deconjugation or clean-up: A possible way forward
article 1998    
Author: Elliott, C.T. · Baxter, G.A. · Hewitt, S.A. · Arts, C.J.M. · Baak, M. van · Hellenäs, K.-E. · Johannson, A.
Keywords: Nutrition · Drug residue · Reagent · Salbutamol · Solvent · Animal experiment · Biosensor · Cattle · Conference paper · Controlled study · Device · Drug conjugation · Drug determination · Drug hydrolysis · Drug urine level · Gas chromatography · Immunoassay · Male · Mass spectrometer · Mass spectrometry · Nonhuman · Oral drug administration · Radioimmunoassay · Adrenergic beta-Agonists · Albuterol · Animals · Biosensing Techniques · Cattle · Drug Residues · Gas Chromatography-Mass Spectrometry · Growth Substances · Immunoassay · Male · Radioimmunoassay · Sensitivity and Specificity
[Abstract]

4 GSTP1-1 stereospecifically catalyzes glutathione conjugation of ethacrynic acid
article 1998    
Author: Iersel, M.L.P.S. van · Lipzig, M.M.H. van · Rietjens, I.M.C.M. · Vervoort, J. · Bladeren, P.J. van
Keywords: EA, ethacrynic acid · Ethacrynic acid · Glutathione S-transferase · Stereoselectivity · Etacrynic acid · Glutathione · Glutathione transferase · Multidrug resistance protein · Chemical reaction · Conjugate · Controlled study · Diastereoisomer · Drug conjugation · Enzyme mechanism · Glutathione metabolism · Human cell · Melanoma cell · Nuclear magnetic resonance spectroscopy · Stereochemistry · Amino Acid Substitution · Ethacrynic Acid · Glutathione · Glutathione Transferase · Humans · Isoenzymes · Melanoma · Point Mutation · Stereoisomerism · Substrate Specificity · Tumor Cells, Cultured
[PDF] [Abstract]

5 Peripheral site ligand conjugation to a non-quaternary oxime enhances reactivation of nerve agent-inhibited human acetylcholinesterase
article 2011    
Author: Koning, M.C. de · Grol, M. van · Noort, D.
Keywords: Acetylcholinesterase · Nerve agent · Non-quaternary oxime · Peripheral site · Reactivation · 4 methoxyphenyl oxo ethanaloxime · Acetylcholinesterase · Cholinesterase reactivator · Oxime · Pyridinium derivative · Unclassified drug · Article · Binding affinity · Blood brain barrier · Drug conjugation · Drug inhibition · Drug structure · Drug synthesis · Electrospray mass spectrometry · Enzyme active site · High performance liquid chromatography · Liquid chromatography · Priority journal · Purification · Chemicals/CAS: acetylcholinesterase, 9000-81-1 · Life · CBRN - CBRN Protection · EELS - Earth, Environmental and Life Sciences
[Abstract]

Search results also available in MS Excel format.

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