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1 Pharmacokinetics and bioavailability of dapsone in the beagle dog
article 1989    
Author: Hekman, P. · Rens, P. van · Rietvel, E.C. · Coert, A.
Keywords: Nutrition · Dapsone · Animal experiment · Dog · Drug bioavailability · Drug blood level · Drug determination · Intravenous drug administration · Nonhuman · Oral drug administration · Preliminary communication
[Abstract]

2 Urine profile analysis by field desorption mass spectrometry, a technique for detecting metabolites of xenobiotics. Application to 3,5-dinitro-2-hydroxytoluene
article 1983    
Author: Greef, J. van der · Leegwater, D.C.
Keywords: Nutrition · Dinitro ortho cresol · Drug metabolite · Radioisotope · Xenobiotic agent · Dinitro ortho cresol c 14 · Drug analysis · Drug determination · Mass spectrometry · Methodology · Nonhuman · Thin layer chromatography · Urine · Animal · Biotransformation · Cresols · Dinitrocresols · Male · Rats · Rats, Inbred Strains · Spectrum Analysis, Mass
[Abstract]

3 High-performance liquid chromatographic determination of urinary free catecholamines with electrochemical detection after prepurification on immobilized boric acid
article 1983    
Author: Speek, A.J. · Odink, J. · Schrijver, J. · Schreurs, W.H.P.
Keywords: Adrenalin · Alpha methyldopamine · Catecholamine · Dopamine · Isoprenaline · Noradrenalin · Drug analysis · Drug determination · Drug urine level · Liquid chromatography · Nonhuman · Theoretical study · Wine · Boric Acids · Catecholamines · Chromatography, High Pressure Liquid · Electrochemistry · Human
[Abstract]

4 Determination of daminozide in apples and apple leaves by liquid chromatography-mass spectrometry
article 1999    
Author: Mol, H.G.J. · Dam, R.C.J. van · Vreeken, R.J. · Steijger, O.M.
Keywords: Nutrition · Apples · Daminozide · Food analysis · Fruits · Daminozide · Apple · Conference paper · Controlled study · Drug determination · Food analysis · Growth regulation · Liquid chromatography · Methodology · Nonhuman · Priority journal · Tandem mass spectrometry · Chromatography, Liquid · Fruit · Mass Spectrometry · Plant Growth Regulators · Sensitivity and Specificity · Succinates · Lonchocarpus capassa · Malus x domestica
[Abstract]

5 Quantification of perifosine, an alkylphosphocholine anti-tumour agent, in plasma by pneumatically assisted electrospray tandem mass spectrometry coupled with high-performance liquid chromatography
article 1999    
Author: Knebel, N.G. · Grieb, S. · Winkler, M. · Locher, M. · Vlis, E. van der · Verheij, E.R.
Keywords: Nutrition · Alkylphosphocholine · Perifosine · Antineoplastic agent · Miltefosine · Perifosine · Unclassified drug · Accuracy · Automation · Calibration · Controlled study · Drug blood level · Drug determination · High performance liquid chromatography · Human · Human experiment · Human tissue · Mass spectrometry · Oral drug administration · Priority journal · Solid phase extraction · Technique · Calibration · Chromatography, High Pressure Liquid · Humans · Mass Spectrometry · Phosphorylcholine · Quality Control · Spectrometry, Fluorescence · Spectrophotometry, Ultraviolet
[Abstract]

6 Use of biosensors for rapid drug residue analysis without sample deconjugation or clean-up: A possible way forward
article 1998    
Author: Elliott, C.T. · Baxter, G.A. · Hewitt, S.A. · Arts, C.J.M. · Baak, M. van · Hellenäs, K.-E. · Johannson, A.
Keywords: Nutrition · Drug residue · Reagent · Salbutamol · Solvent · Animal experiment · Biosensor · Cattle · Conference paper · Controlled study · Device · Drug conjugation · Drug determination · Drug hydrolysis · Drug urine level · Gas chromatography · Immunoassay · Male · Mass spectrometer · Mass spectrometry · Nonhuman · Oral drug administration · Radioimmunoassay · Adrenergic beta-Agonists · Albuterol · Animals · Biosensing Techniques · Cattle · Drug Residues · Gas Chromatography-Mass Spectrometry · Growth Substances · Immunoassay · Male · Radioimmunoassay · Sensitivity and Specificity
[Abstract]

7 Effects of thiourea and ammonium bicarbonate on the formation and stability of bifunctional cisplatin-DNA adducts : consequences for the accurate quantification of adducts in (cellular) DNA
article 1995    
Author: Fichtinger-Schepman, A.M.J. · Dijk-Knijnenburg, H.C.M. van · Dijt, F.J. · Velde-Visser, S.D. van der · Berends, F. · Baan, R.A.
Keywords: Nutrition · Ammonium derivative · Bicarbonate · Cell dna · Cisplatin · Dna · Thiourea · Animal cell · Cho cell · Dna adduct · Drug determination · Drug dna interaction · Nonhuman · Animal · Bicarbonates · Cell Survival · CHO Cells · Chromatography, Ion Exchange · Cisplatin · Cricetulus · Deoxyribonucleases · DNA Adducts · Hamsters · Support, Non-U.S. Gov't · Thiourea · Animalia · Cricetinae · Cricetulus griseus
[Abstract]

8 Detection of zilpaterol (Zilmax®) in calf urine and faeces with liquid chromatography-tandem mass spectrometry
article 2005    
Author: Hoof, N. van · Schilt, R. · Vlis, E. van der · Boshuis, P. · Baak, M. van · Draaijer, A. · Wasch, K. de · Wiele, M. van de · Hende, J.V. van · Courtheyn, D. · Brabander, H. de
Keywords: Toxicology · Analytical research · Beta-agonists · Excretion profile · LC-MSn · Zilpaterol · Body fluids · Liquid chromatography · Mass spectrometry · Optimization · Calf urine · Faeces · Fattening · Zilpaterol · Alcohols · beta adrenergic receptor stimulating agent · unclassified drug · zilmax · zilpaterol · animal experiment · animal tissue · cattle · conference paper · controlled study · drug determination · drug excretion · drug structure · gas chromatography · liquid chromatography · male · mass spectrometry · nonhuman · priority journal · tandem mass spectrometry · urinalysis · Bos taurus
[Abstract]

9 In vitro liver models are important tools to monitor the abuse of anabolic steroids in cattle
article 1998    
Author: Puymbroeck, M. van · Kuilman, M.E.M. · Maas, R.F.M. · Witkamp, R.F. · Leyssens, T. · Zande, D.J.M. van der · Gelan, J. · Raus, J.
Keywords: Nutrition · Anabolic agent · Biological marker · Boldenone · Clostebol · Estrane derivative · Ethylestrenol · Norethandrolone · Steroid · Animal tissue · Cattle · Conference paper · Controlled study · Drug abuse · Drug determination · Drug metabolism · Drug monitoring · Female · Liver · Liver cell culture · Liver metabolism · Liver microsome · Male · Model · Nonhuman · Steroid metabolism · Anabolic Agents · Animals · Biological Markers · Cattle · Cells, Cultured · Drug Residues · Estradiol · Ethylestrenol · Liver · Microsomes, Liver · Models, Biological · Norethandrolone · Predictive Value of Tests · Testosterone
[PDF] [Abstract]

10 Lost in translation? Role of metabolomics in solving translational problems in drug discovery and development
article 2006    
Author: Greef, J. van der · Adourian, A. · Muntendam, P. · McBurney, R.N.
Keywords: Biology · Analytical research · biological marker · drug metabolite · new drug · bioinformatics · body fluid · data base · decision making · drug determination · drug efficacy · drug marketing · drug research · drug safety · human · medical technology · metabolomics · multiple sclerosis · non insulin dependent diabetes mellitus · nonhuman · osteoarthritis · phenotype · postmarketing surveillance · proteomics · review · serology · structure activity relation
[Abstract]

11 Determination of the B2 vitamer flavin-adenine dinucleotide in whole blood by high-performance liquid chromatography with fluorometric detection
article 1982    
Author: Speek, A.J. · Schaik, F. van · Schrijver, J. · Schreurs, W.H.P.
Keywords: Nutrition · Flavine adenine nucleotide · Flavine nucleotide · Riboflavin · Nicotinamide adenine dinucleotide · Blood · Blood and hemopoietic system · Drug blood level · Drug determination · Fluorometry · High performance liquid chromatography · Human · Human cell · In vitro study · Methodology · Normal human · Normal value · Preliminary communication · Theoretical study · Article · Chemistry · Spectrofluorometry · Chromatography, High Pressure Liquid · Human · Microchemistry · NAD · Spectrometry, Fluorescence
[Abstract]

12 Fluorometric determination of retinol in human tear fluid using high-performance liquid chromatography
article 1986    
Author: Speek, A.J. · Agtmaal, E.J. van · Saowakontha, S. · Schreurs, W.H.P. · Haeringen, N.J. van
Keywords: Retinol · Drug analysis · Drug determination · Drug tissue level · Fluorometry · High performance liquid chromatography · Human · Human cell · Methodology · Normal human · Tear · Visual system · Chromatography, High Pressure Liquid · Drug Stability · Evaluation Studies · Fluorometry · Human · Support, Non-U.S. Gov't · Tears · Vitamin A · Biology · Biochemistry · Medicine · Geneeskunde
[Abstract]

13 Generic solid phase extraction-liquid chromatography-tandem mass spectrometry method for fast determination of drugs in biological fluids
article 2003    
Author: Schellen, A. · Ooms, B. · Lagemaat, D. van de · Vreeken, R. · Dongen, W.D. van
Keywords: Drugs Pharmacology · Analytical research · Drug analysis · Generic method · Body fluids · Drug products · Mass spectrometers · Solid phase extraction · High performance liquid chromatography · caffeine · carbamazepine · paclitaxel · paracetamol · procainamide · propranolol · ranitidine · sulfadiazine · sulfamerazine · theobromine · theophylline · accuracy · article · controlled study · drug blood level · drug determination · high performance liquid chromatography · human · linear system · physical chemistry · priority journal · quantitative analysis · solid phase extraction · tandem mass spectrometry · technique · time · Chromatography, High Pressure Liquid · Humans · Mass Spectrometry · Pharmaceutical Preparations · Reproducibility of Results · Sensitivity and Specificity · Spectrophotometry, Ultraviolet
[Abstract]

14 Capillary gas chromatographic analysis of nerve agents using large volume injections
article 1996    
Author: Degenhardt, C.E.A.M. · Kientz, C.E.
Keywords: Biology · GC - Gas chromatography · Nerve agents · Capillarity · Phosphorus organic compounds · GB agent · Military chemical agents · Cholinesterase Inhibitors · Isoflurophate, 55-91-4 · Organophosphorus compounds · Organothiophosphorus compounds · Sarin, 107-44-8 · Soman, 96-64-0 · VX, 50782-69-9 · Water, 7732-18-5 · Chemical warfare agents · DFP · Large volume injection · Organophosphorus compounds · Tabun · Dflos · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester · Capillary gas chromatography · Drug determination · Nonhuman · Sample · Technique · Water analysis · Water pollution · Cholinesterase Inhibitors · Chromatography, Gas · Hydrogen-Ion Concentration
[Abstract]

15 Detection of hormonal anabolic compounds in calf urine and unverified growth-promoting preparations : application of the AR-LUX bioassay for screening and determination of androgenic activity
article 2003    
Author: Blankvoort, B.M.G. · Aarts, J.M.M.J.G. · Schilt, R. · Geerdink, P. · Spenkelink, B. · Rodenburg, R.J.T.
Keywords: Biology · Analytical research · Anabolic agent · Androgen · Boldenone · Drug residue · Luciferase · Androgen receptor mediated luciferase expression system · Animal · Animal experiment · Bioassay · Body growth · Cattle · Cell line · Conference paper · Controlled study · Cytotoxicity · Drug determination · Enzyme assay · European Union · Female · Food contamination · Gene expression · Human · Human cell · Liquid liquid extraction · Male · Methodology · Nonhuman · Reporter gene · Tumor cell line · Urine · Urine level · Anabolic Agents · Animals · Biological Assay · Cattle · Cell Line, Tumor · Drug Residues · Female · Food Contamination · Humans · Luciferases
[Abstract]

16 Recent methodology in the phytochemical analysis of ginseng
article 2008    
Author: Angelova, N. · Kong, H.-W. · Heijden, R. van de · Yang, S.-Y. · Choi, Y.H. · Kim, H.K. · Wang, M. · Hankemeier, T. · Greef, J. van der · Xu, G. · Verpoorte, R.
Keywords: Health · Biomedical Research · Ginsenosides · Mass spectrometry · Metabolomics · Panax ginseng · Ginseng extract · Phenol · Saponin · Analytic method · Antineoplastic activity · Biosensor · Drug absorption · Drug determination · Drug distribution · Drug efficacy · Drug excretion · Drug half life · Drug metabolism · Drug safety · Drug structure · Electrospray mass spectrometry · Enzyme linked immunosorbent assay · Fourier transform mass spectrometry · Ginseng · High performance liquid chromatography · Human · Immunoregulation · Ion cyclotron resonance mass spectrometry · Liquid chromatography · Liver protection · Mass spectrometry · Metabolomics · Near infrared reflectance spectroscopy · Nonhuman · Nuclear magnetic resonance spectroscopy · Plant root · Quality control · Review · Sensitivity analysis · Structure analysis · Systems biology · Drugs, Chinese Herbal · Ginsenosides · Mass Spectrometry · Panax · Spectroscopy, Fourier Transform Infrared · Spectroscopy, Near-Infrared · Panax ginseng
[Abstract]

17 Determination of kava lactones in food supplements by liquid chromatography-atmospheric pressure chemical ionisation tandem mass spectrometry
article 2005    
Author: Bobeldijk, I. · Boonzaaijer, G. · Spies-Faber, E.J. · Vaes, W.H.J.
Keywords: Biology · Analytical research · Kava lactones · Liquid chromatography · Piper methysticum · Tandem mass spectrometry · Atmospheric pressure · Drug products · Ionization · Liquid chromatography · Mass spectrometry · Nuclear magnetic resonance · Sugars · Food supplements · Herbal mixtures · Herbal products · Kava extracts · Ketones · desmethoxyyangonin · dihydrokawain · dihydromethysticin · herbaceous agent · kava extract · kawain · lactone · methysticin · unclassified drug · yangonin · article · cis isomer · diet supplementation · drug degradation · drug determination · mass spectrometry · nuclear magnetic resonance imaging · priority journal · reversed phase liquid chromatography · validation process · Atmospheric Pressure · Calibration · Chromatography, Liquid · Food Analysis · Kava · Magnetic Resonance Spectroscopy · Mass Spectrometry · Reference Standards · Reproducibility of Results · Piper methysticum
[Abstract]

18 Effects of growth conditions and processing on Rehmannia glutinosa using fingerprint strategy
article 2006    
Author: Chang, W.T. · Thissen, U. · Ehlert, K.A. · Koek, M.M. · Jellema, R.H. · Hankemeier, T. · Greef, J. van der · Wang, M.
Keywords: Biology · Analytical research · ANOVA-simultaneous component analysis · ASCA · GC-MS · Herbal medicine · Metabolite profiling · Principal component analysis · Processing of traditional Chinese medicine · Quality control · Rehmannia glutinosa L. · Drug metabolite · Herbaceous agent · Natural product · Rehmannia glutinosa extract · Analysis of variance · Chinese medicine · Drug determination · Drug manufacture · Drug quality · Gas chromatography · Mass spectrometry · Nonhuman · Plant growth · Plant metabolism · Plant root · Principal component analysis · Quality control · Rehmannia · Rehmannia glutinosa · Climate · Drugs, Chinese Herbal · Gas Chromatography-Mass Spectrometry · Humans · Phytotherapy · Principal Component Analysis · Quality Control · Rehmannia · Soil · Rehmannia · Rehmannia glutinosa
[Abstract]

19 PAF-acether-induced release of tissue-type plasminogen activator from vessel walls
article 1985    
Author: Emeis, J.J. · Kluft, C.
Keywords: Biology · 3 amino 1 (3 trifluoromethylphenyl) 2 pyrazoline · 4 bromophenacyl bromide · Acetylsalicylic acid · Diethylcarbamazine · Docebenone · Endetic acid · Indometacin · Mepacrine · Nordihydroguaiaretic acid · Plasminogen activator · Thrombocyte activating factor · Tissue plasminogen activator · Animal experiment · Biological model · Blood and hemopoietic system · Blood clotting · Blood vessel wall · Cardiovascular system · Dose response · Drug accumulation · Drug analysis · Drug blood level · Drug comparison · Drug determination · Drug identification · Drug inhibition · Drug isolation · Drug mechanism · Drug response · Histology · Intravenous drug administration · Nonhuman · Peripheral vascular system · Regional perfusion · Spectrophotometry · Thrombocyte aggregating factor · Animal · Blood Vessels · Calcium · Cyclooxygenase Inhibitors · Fibrinolysis · Lipoxygenase Inhibitors · Male · Phospholipases · Plasminogen Activators · Platelet Activating Factor · Rats · Rats, Inbred Strains · Support, Non-U.S. Gov't
[Abstract]

20 Development and validation of a quantitative method for the determination of 12 endocannabinoids and related compounds in human plasma using liquid chromatography-tandem mass spectrometry
article 2009    
Author: Balvers, M.G.J. · Verhoeckx, K.C.M. · Witkamp, R.F.
Keywords: Biology · Analytical research · Biomedical research · Endocannabinoids · Human plasma · LC-MS/MS · Sample pre-treatment · Endocannabinoids · Gradient elutions · Human plasma · LC-MS/MS · Liquid chromatography-tandem mass spectrometries · Quadrupole · Quantitative methods · Related compounds · Sample pre-treatment · Solid-phase extractions · Acetonitrile · Brain · Chromatographic analysis · Ethers · Glycerol · High performance liquid chromatography · Mass spectrometry · Phase separation · Plasma (human) · Plasmas · Extraction · 2 arachidonoylglycerol · 2 arachidonylglycerol ether · anandamide · dihomo gamma linolenoylethanolamide · docosatetraenoylethanolamide · dopamine derivative · endocannabinoid · ethanolamine · glycine derivative · n arachidonoylglycine · n arachidonyldopamine · n oleoyl dopamine · n oleoylethanolamine · o arachidonoylethanolamide · octadecylamine · palmidrol · stearoylethanolamide · unclassified drug · article · diagnostic accuracy · drug determination · drug isolation · human · human cell · liquid chromatography · priority journal · quantitative analysis · sensitivity and specificity · solid phase extraction · tandem mass spectrometry · validation process · Chromatography, Liquid · Endocannabinoids · Humans · Tandem Mass Spectrometry
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 22 found. Next | Sort by date