Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 20 of 38 found. Next | Sort by date

1 On the mode of action of 3 phenylindole towards Aspergillus niger
article 1976    
Author: Hoppe, H.H. · Kerkenaar, A. · Kaars Sypesteyn, A.
Keywords: Biology · Ergosterol · Phospholipid · Radioisotope · Sterol · 3 phenylindole · Aspergillus niger · Drug mechanism · Drug sensitivity · Fungus · Microorganism · Phosphoric acid p 31 · Theoretical study
[Abstract]

2 On the antifungal mode of action of metalaxyl, an inhibitor of nucleic acid synthesis in Pythium splendens
article 1981    
Author: Kerkenaar, A.
Keywords: Biology · Metalaxyl · Mithramycin · Radioisotope · Animal experiment · Bisbenzimide h 3 · Cytotoxicity · Dna synthesis · Drug absorption · Drug mechanism · Fungus · Heredity · Histology · Lipogenesis · Metalaxyl c 14 · Nucleic acid synthesis · Oomycetes · Protein synthesis · Rna synthesis
[Abstract]

3 Bile acids and lipids in isolated rat hepatocytes : Content, synthesis, and release, as affected by cholestyramine treatment of the donor rats
article 1982    
Author: Kempen, H.J.M. · Vos-Holstein, P.M. van · Lange, J. de
Keywords: Biology · Bile acid · Radioisotope · Triacylglycerol · Animal cell · Beta muricholic acid · Cell culture · Controlled study · Drug mechanism · In vitro study · Liver cell · Nonhuman · Oral drug administration · Therapy · Animal · Bile Acids and Salts · Cholestyramine · Lipids · Liver · Male · Rats · Rats, Inbred Strains · Triglycerides
[PDF] [Abstract]

4 The role of colonic metabolism in lactose intolerance
article 2008    
Author: He, T. · Venema, K. · Priebe, M.G. · Welling, G.W. · Brummer, R.J.M. · Vonk, R.J.
Keywords: Nutrition · Biomedical Research · Colonic microbiota · Fermentation · Lactose intolerance · Antibiotic agent · Lactic acid · Lactose · Prebiotic agent · Probiotic agent · Succinic acid · Synbiotic agent · Colon flora · Diarrhea · Diet supplementation · Drug mechanism · Fermentation · Flatulence · Human · Irritable colon · Lactase deficiency · Lactose intolerance · Loose feces · Metabolism · Nonhuman · Priority journal · Review · Bifidobacterium · Colon · Fermentation · Humans · Lactates · Lactose · Lactose Intolerance
[Abstract]

5 Toxicological evaluation and risk assessment of chemical mixtures
article 1998    
Author: Cassee, F.R. · Groten, J.P. · Bladeren, P.J. van · Feron, V.J.
Keywords: Nutrition · Combination toxicology · Complex mixtures · Isoboles · Physiologically based toxicokinetic modeling · Response surface analysis · Simple mixtures · Weight of evidence approach · Chemical compound · Chemical analysis · Dose response · Drug mechanism · Drug potentiation · Environmental exposure · Review · Risk assessment · Toxin analysis · Animals · Drug Interactions · Drug Synergism · Guidelines · International Cooperation · Male · Models, Biological · Models, Statistical · No-Observed-Adverse-Effect Level · Rats · Risk Assessment · Xenobiotics
[Abstract]

6 Modulation of plasma fibrinogen levels by ciprofibrate and gemfibrozil in primary hyperlipidaemia
article 1997    
Author: Maat, M.P.M. de · Knipscheer, H.C. · Kastelein, J.J.P. · Kluft, C.
Keywords: Biology · C reactive protein · Ciprofibrate · Acute phase response · Cardiovascular disease · Clinical trial · Controlled clinical trial · Controlled study · Drug effect · Drug mechanism · Fibrinogen blood level · Genetic polymorphism · Hypercholesterolemia · Major clinical study · Oral drug administration · Randomized controlled trial · Risk factor · Adult · Antilipemic Agents · Clofibric Acid · Female · Fibrinogen · Gemfibrozil · Humans · Hyperlipidemias · Male · Middle Aged
[Abstract]

7 Anticoagulant and calcium-binding properties of high molecular weight derivatives of human fibrinogen (plasmin fragments Y)
article 1982    
Author: Nieuwenhuizen, W. · Voskuilen, M. · Hermans, J.
Keywords: Biology · alanine · anticoagulant agent · calcium · fibrinogen · fructose bisphosphate · plasmin · tyrosine · blood and hemopoietic system · drug binding · drug mechanism · fragmentation · human · metal binding · pharmacology · structure activity relation · Binding Sites · Blood Coagulation · Calcium · Fibrin Fibrinogen Degradation Products · Fibrinogen · Human · Kinetics · Plasmin · Protein Binding · Support, Non-U.S. Gov't
[Abstract]

8 Kombucha fermentation and its antimicrobial activity
article 2000    
Author: Sreeramulu, G. · Zhu, Y. · Knol, W.
Keywords: Nutrition · Sucrose · Unclassified drug · Antibiotic sensitivity · Antimicrobial activity · Bacterium · Beverage · Campylobacter jejuni · Drug decomposition · Drug effect · Drug mechanism · Escherichia coli · Fermentation · Growth, development and aging · Microbiological examination · Nonhuman · Salmonella enteritidis · Salmonella typhimurium · Shigella sonnei · Bacteria · Beverages · Fermentation · Microbial Sensitivity Tests · Plant Extracts · Plants, Medicinal · Sucrose
[Abstract]

9 The antiinflammatory drug sulfasalazine inhibits tumor necrosis factor alpha expression in macrophages by inducing apoptosis
article 2000    
Author: Rodenburg, R.J.T. · Ganga, A. · Lent, P.L.E.M. van · Putte, L.B.A. van de · Venrooij, W.J. van
Keywords: Nutrition · Medicine · Geneeskunde · Pharmacology · Toxicology · Caspase 8 · Salazosulfapyridine · Tumor necrosis factor alpha · Animal cell · Antiinflammatory activity · Apoptosis · Crohn disease · Cytokine production · Drug mechanism · Macrophage · Mouse · Nonhuman · Priority journal · Protein expression · Rheumatoid arthritis · Adenosine · Animals · Anti-Inflammatory Agents, Non-Steroidal · Apoptosis · Caspases · Cells, Cultured · Cysteine Proteinase Inhibitors · Humans · Macrophage Activation · Macrophages · Macrophages, Peritoneal · Methotrexate · Mice · Mice, Inbred C57BL · Sulfasalazine · Tumor Necrosis Fac
[Abstract]

10 Predicting individual responses to pravastatin using a physiologically based kinetic model for plasma cholesterol concentrations
article 2014    
Author: Pas, N.C.A. van de · Rullmann, J.A.C. · Woutersen, R.A. · Ommen, B. van · Rietjens, I.M.C.M. · Graaf, A.A. de
Keywords: Biology · Cholesterol · LDL · PBK modeling · Personalized medicine · Statin response · Virtual subjects · cholesterol · High density lipoprotein cholesterol · Low density lipoprotein cholesterol · Low density lipoprotein receptor · Pravastatin · Very low density lipoprotein cholesterol · Cholesterol blood level · Cholesterol synthesis · Drug effect · Drug mechanism · Human · Kinetics · Major clinical study · Monte Carlo method · Physiologically based kinetic · Protein expression · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

11 Tissue culture and neurotoxicology
article 1982    
Author: Hooisma, J.
Keywords: Biology · Acrylamide · Colchicine · Glutathione · Nicotinamide adenine dinucleotide · Animal cell · Brain cell · Central nervous system · Dose response · Drug comparison · Drug mechanism · Drug mixture · Drug response · Drug screening · In vitro study · Intoxication · Methodology · Nervous system · Neurotoxicity · Nonhuman · Rat · Tissue culture · Acrylamide · Acrylamides · Animal · Axons · Colchicine · Female · Ganglia, Spinal · Glutathione · Male · NAD · Nervous System Diseases · Rats · Rats, Inbred Strains · Support, Non-U.S. Gov't · Tissue Culture · Toxicology
[Abstract]

12 Fenofibrate increases HDL-cholesterol by reducing cholesteryl ester transfer protein expression
article 2007    
Author: Hoogt, C.C. van der · Haan, W. de · Westerterp, M. · Hoekstra, M. · Dallinga-Thie, G.M. · Romijn, J.A. · Princen, H.M.G. · Jukema, J.W. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Biomedical Research · Fibrate · High density lipoprotein · Peroxisome proliferator-activated receptor α · Transgenic mice · apolipoprotein E · cholesterol ester transfer protein · fenofibrate · high density lipoprotein cholesterol · very low density lipoprotein · animal experiment · cholesterol transport · controlled study · drug mechanism · food intake · gene expression · lipid metabolism · mouse · nonhuman · priority journal · protein expression · protein function · steady state · transgene · Animals · Antilipemic Agents · Apolipoproteins B · Cholesterol Ester Transfer Proteins · Cholesterol Esters · Cholesterol, HDL · Gene Expression · Humans · Liver · Male · Mice · Mice, Transgenic · Procetofen · RNA, Messenger
[PDF] [Abstract]

13 Cholesteryl ester transfer protein inhibition: Effect on reverse cholesterol transport?
article 2006    
Author: Rensen, P.C.N. · Havekes, L.M.
Keywords: Biology · Biomedical Research · 2 methylpropanethioic acid s [2 [1 (2 ethylbutyl)cyclohexylcarboxamido]phenyl] ester · Atorvastatin · Cholesterol ester transfer protein inhibitor · Fibric acid derivative · High density lipoprotein cholesterol · Hydroxymethylglutaryl coenzyme A reductase inhibitor · Nicotinic acid · Torcetrapib · Atherosclerosis · Cholesterol transport · Clinical trial · Drug efficacy · Drug mechanism · Dyslipidemia · Editorial · Ischemic heart disease · Nonhuman · Plasma clearance · Protein expression · Reverse cholesterol transport · Animals · Biological Transport · Cardiovascular Diseases · Carrier Proteins · Cholesterol Ester Transfer Proteins · Cholesterol Esters · Cholesterol, HDL · Glycoproteins · Humans · Lipid Metabolism · Lipoproteins, HDL · Rabbits · Risk Factors
[Abstract]

14 Aspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet
article 2011    
Author: Diepen, J.A. van · Vroegrijk, I.O.C.M. · Berbée, J.F.P. · Shoelson, S.E. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N. · Voshol, P.J.
Keywords: Biology · Inflammation · Lipid metabolism · Very low-density lipoprotein · acetylsalicylic acid · apolipoprotein C1 · immunoglobulin enhancer binding protein · transcription factor RelA · triacylglycerol · very low density lipoprotein cholesterol · animal experiment · animal model · article · cholesterol blood level · controlled study · drug mechanism · drug targeting · enzyme inhibition · gene expression · hypertriglyceridemia · in vivo study · lipid diet · lipogenesis · lipoprotein blood level · male · metabolic syndrome X · mouse · nonhuman · priority journal · protein expression · risk factor · triacylglycerol blood level · aspirin · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

15 Differentiating the mechanisms of antiresorptive action of nitrogen containing bisphosphonates
article 2003    
Author: Beek, E.R. van · Cohen, L.H. · Leroy, I.M. · Ebetino, F.H. · Löwik, C.W.G.M. · Papapoulos, S.E.
Keywords: Biomedical Research · Bisphosphonates · Bone resorption · FPP synthase · Geranylgeranylation · Osteoclasts · alendronic acid · bisphosphonic acid derivative · etidronic acid · geranylgeraniol · geranyltransferase · isopentenyl diphosphate delta isomerase · ne 10575 · ne 11808 · ne 21650 · ne 58086 · nitrogen · pamidronic acid · risedronic acid · unclassified drug · animal experiment · animal tissue · article · controlled study · drug activity · drug effect · drug mechanism · drug potency · enzyme activity · enzyme repression · female · fetus · nonhuman · osteoclast · osteolysis · structural homology · Animals · Bone Resorption · Calcium · Diphosphonates · Dose-Response Relationship, Drug · Female · Metatarsal Bones · Mice · Nitrogen · Organ Culture Techniques · Pregnancy
[Abstract]

16 Modifying effect of vitamin A on benzo[a]pyrene-induced respiratory tract tumours in hamsters
article 1984    
Author: Beems, R.B.
Keywords: Benzo[a]pyrene · Retinol · Animal experiment · Animal model · Chemical carcinogenesis · Dose response · Drug administration · Drug blood level · Drug efficacy · Drug mechanism · Drug response · Electron microscopy · Epidemiology · Fatality · Mortality · Nonhuman · Oral drug administration · Prevention · Respiratory system · Respiratory tract tumor · Sex difference · Animal · Benzo(a)pyrene · Benzopyrenes · Body Weight · Dose-Response Relationship, Drug · Drug Interactions · Eating · Female · Hamsters · Male · Mesocricetus · Precancerous Conditions · Respiratory Tract Neoplasms · Sex Factors · Support, Non-U.S. Gov't · Vitamin A
[Abstract]

17 Intracerebroventricular administration of neuropeptide Y induces hepatic insulin resistance via sympathetic innervation
article 2008    
Author: Hoek, A.M. van den · Heijningen, C. van · Schröder - Elst, J.P. van der · Ouwens, D.M. · Havekes, L.M. · Romijn, J.A. · Kalsbeek, A. · Pijl, H.
Keywords: corticosterone · glucose · insulin · liothyronine · neuropeptide Y · testosterone · thyroxine · antidiabetic agent · animal experiment · animal model · animal tissue · article · controlled study · drug mechanism · glucose metabolism · hormone blood level · insulin resistance · liver · male · nonhuman · parasympathetic innervation · priority journal · rat · sympathetic innervation · adrenergic system · animal · drug effect · glucose blood level · glucose clamp technique · hyperinsulinism · innervation · intracerebroventricular drug administration · metabolism · pathophysiology · physiology · sympathectomy · vagotomy · Wistar rat · Animals · Blood Glucose · Glucose Clamp Technique · Hyperinsulinism · Hypoglycemic Agents · Injections, Intraventricular · Insulin · Insulin Resistance · Liver · Male · Neuropeptide Y · Parasympathectomy · Rats · Rats, Wistar · Sympathectomy · Sympathetic Nervous System
[Abstract]

18 Comparison of a transdermal contraceptive patch vs. oral contraceptives on hemostasis variables
article 2008    
Author: Kluft, C. · Meijer, P. · LaGuardia, K.D. · Fisher, A.C.
Keywords: Health · Fibrin · Monophasic · Procoagulation · Prothrombin · Triphasic · contraceptive agent · D dimer · desogestrel plus ethinylestradiol · ethinylestradiol plus levonorgestrel · fibrin degradation product · oral contraceptive agent · plasmin inhibitor · protein S · prothrombin · sex hormone binding globulin · activated protein C resistance · adult · article · blood clotting · blood sampling · clinical trial · controlled clinical trial · controlled study · drug mechanism · female · hemostasis · human · intermethod comparison · major clinical study · open study · patch test · randomized controlled trial · Administration, Cutaneous · Administration, Oral · Adolescent · Adult · Antifibrinolytic Agents · Biological Markers · Blood Coagulation · Blood Coagulation Factors · Contraceptives, Oral, Combined · Desogestrel · Ethinyl Estradiol · Female · Fibrin Fibrinogen Degradation Products · Homeostasis · Humans · Levonorgestrel · Middle Aged · Peptide Fragments · Plasmin · Prospective Studies · Protein Precursors · Prothrombin
[Abstract]

19 Studies on the mechanism of fibrate-inhibited expression of plasminogen activator inhibitor-1 in cultured hepatocytes from cynomolgus monkey
article 1997    
Author: Arts, J. · Kooistra, T.
Keywords: Biology · 9-cis retinoic acid · fibrates · hepatocytes · peroxisome proliferator-activated receptor · plasminogen activator inhibitor-1 · 2 [1 (3 amidinothiopropyl) 1h indol 3 yl] 3 (1 methyl 1h indol 3 yl)maleimide · alitretinoin · antilipemic agent · epidermal growth factor · fibric acid derivative · gemfibrozil · peroxisome proliferator · phorbol 13 acetate 12 myristate · plasminogen activator inhibitor 1 · protein kinase C · protein kinase C inhibitor · retinoid X receptor · transforming growth factor beta · animal cell · controlled study · dose time effect relation · drug mechanism · enzyme activity · gene expression · hyperlipidemia · liver cell culture · monkey · nonhuman · Animals · Antilipemic Agents · Cells, Cultured · Dose-Response Relationship, Drug · Liver · Macaca fascicularis · Plasminogen Activator Inhibitor 1 · RNA, Messenger
[Abstract]

20 Soluble mannosylated myelin peptide inhibits the encephalitogenicity of autoreactive T cells during experimental autoimmune encephalomyelitis
article 2007    
Author: Kel, J. · Oldenampsen, J. · Luca, M. · Drijfhout, J.W. · Koning, F. · Nagelkerken, L.
Keywords: Biology · Biomedical Research · gamma interferon · interleukin 23 · major histocompatibility antigen class 2 · myelin · proteolipid · autoantigen · epitope · lymphocyte antigen receptor · mannose · peptide fragment · proteolipid protein · proteolipid protein 139 151 · proteolipid protein 139-151 · allergic encephalomyelitis · animal cell · animal experiment · animal model · animal tissue · article · controlled study · drug mechanism · female · histopathology · immunization · immunomodulation · immunoreactivity · incidence · macrophage · mouse · nonhuman · priority journal · solubility · spinal cord · T lymphocyte · animal · chemistry · drug effect · immunology · inflammation · lymphocyte activation · pathology · Animals · Autoantigens · Encephalomyelitis, Autoimmune, Experimental · Female · Immunodominant Epitopes · Inflammation · Lymphocyte Activation · Mannose · Mice · Myelin Proteolipid Protein · Peptide Fragments · Receptors, Antigen, T-Cell · Spinal Cord · T-Lymphocytes
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 38 found. Next | Sort by date