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1 Feasibility of SPECT-CT imaging to study the pharmacokinetics of antisense oligonucleotides in a mouse model of Duchenne muscular dystrophy
article 2017    
Author: Steeg, E. van de · Läppchen, T. · Aguilera, B. · Jansen, H.T. · Muilwijk, D. · Vermue, R. · Hoorn, J.W. van der · Donato, K. · Rossin, R. · Visser, P.C. de · Vlaming, M.L.H.
Keywords: Nutrition · SPECT imaging · Antisense oligonucleotides · RNA-based therapeutics · Duchenne muscular dystrophy · Antisense oligonucleotides · Antisense oligonucleotide i 123 · Antisense oligonucleotide in 111 · Indium 111 · Iodine 123 · Tracer · Unclassified drug · Animal experiment · Animal model · Animal tissue · Controlled study · Drug distribution · Drug half life · Drug tissue level · Drug uptake · In vivo study · Male · Mouse · Mouse model · Nonhuman · Single photon emission computed tomography-computed tomography · Skeletal muscle · Target tissue · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

2 Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3
article 2014    
Author: Gozalpour, E. · Greupink, R. · Wortelboer, H.M. · Bilos, A. · Schreurs, M. · Russel, F.G.M. · Koenderink, J.B.
Keywords: Biology Pharmacology · Bufadienolides · Cardenolides · Cell transport · Convallatoxin · Digitalis-like compounds · Dihydroouabain · Drug-induced toxicity · NTCP · OATP1B1 · OATP1B3 · Ouabagenin · Ouabain · Cardiac glycoside · Convallatoxin · Cymarin · Dehydroouabain · Digitoxigenin · Digitoxin · Digoxigenin · Digoxin · Dihydroouabain · Estradiol 17 glucuronide · Gitoxigenin · Hydroxyl group · Ouabagenin · Ouabain · Peruvoside · Plant glycoside · Proscillaridin · Sodium bile acid cotransporter · Solute carrier organic anion transporter 1B1 · Solute carrier organic anion transporter 1B3 · Strophanthidin · Strophanthidol · Sugar · Taurocholic acid · Unclassified drug · Animal cell · Chemical structure · CHO cell line · Controlled study · Drug interaction · Drug uptake · Embryo · Human · Human cell · IC 50 · Kidney cell · Liquid chromatography · Mass spectrometry · Nonhuman · Food and Nutrition · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

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