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Showing 1 to 20 of 24 found. Next | Sort by date

1 The impact of delayed storage on the measured proteome and metabolome of human cerebrospinal fluid
article 2011    
Author: Rosenling, T. · Stoop, M.P. · Smolinska, A. · Muilwijk, B. · Coulier, L. · Shi, S. · Dane, A. · Christin, C. · Suits, F. · Horvatovich, P.L. · Wijmenga, S.S. · Buydens, L.M.C. · Vreeken, R. · Hankemeier, T. · Gool, A.J. van · Luider, T.M. · Bischoff, R.
Keywords: Nutrition · Healthy Living · Life Triskelion BV · QS - Quality & Safety AR - Analytical Research · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

2 Di-n-octyltin dichloride (DOTC) induced developmental immunotoxicity in male rats after juvenile exposure
article 2011    
Author: Tonk, E.C. · Verhoef, A. · Fonteyne, L.J. de la · Waalkens-Berendsen, I.D. · Wolterbeek, A.P.M. · Loveren, H. van · Piersma, A.H.
Keywords: Toxicology · Biomedical Innovation · Healthy Living · Life Triskelion · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences TNO Bedrijven

3 The OSIRIS Weight of Evidence approach: ITS mutagenicity and ITS carcinogenicity.
article 2013    
Author: Buist, H. · Aldenberg, T. · Batke, M. · Escher, S. · Kühne, R. · Marquart, H. · Pauné, E. · Rorije, E. · Schüürmann, G. · Kroese, D.E.
Keywords: Health Toxicology Pharmacology · Biomedical Innovation · Healthy Living · Life Triskelion · QS - Quality & Safety CRA - Chemical Risk Analysis · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

4 Comprehensive Analysis of Umami Compounds by Ion-Pair Liquid Chromatography Coupled to Mass Spectrometry
article 2011    
Author: Coulier, L. · Bas, R. · Hekman, M. · Werff, B.J.C. van der · Burgering, M. · Thissen, U.
Keywords: Nutrition · 5'-ribonucleotides · Ion-pair LC-MS · Metabolite profiling · Tomato · Umami · Life Triskelion BV · QS - Quality & Safety AR - Analytical Research · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

5 Potentially increased sensitivity of pregnant and lactating female rats to immunotoxic agents
article 2012    
Author: Menke, A. · Wolterbeek, A. · Snel, C. · Bruijntjes, J. · Groot, D.D. · Oostrum, L.V. · Waalkens, I. · Kuper, C.F.
Keywords: Biology · DOTC · immunotoxicity · lactation · pregnancy · sensitive periods · thymus · Healthy for Life · Healthy Living · Life Triskelion · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

6 Evaluation of C-reactive protein as an inflammatory biomarker in rabbits for vaccine nonclinical safety studies
article 2013    
Author: Destexhe, E. · Prinsen, M.K. · Schöll, I. van · Kuper, C.F. · Garçon, N. · Veenstra, S. · Segal, L.
Keywords: Biology · Adjuvant · C-reactive protein · Fibrinogen · Inflammation · Rabbit · Safety/toxicity methods · Vaccine · Biomedical Innovation · Healthy Living · Life Triskelion BV · QS - Quality & Safety TARA - Toxicology and Risk Assessment · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

7 Feasibility of a 3D human airway epithelial model to study respiratory absorption
article 2014    
Author: Reus, A.A. · Maas, W.J.M. · Jansen, H.T. · Constant, S. · Staal, Y.C.M. · Triel, J.J. van · Kuper, C.F.
Keywords: Biology · Respiratory absorption · 3D human airway model · Biomedical Innovation · Healthy Living · Life Triskelion BV · TARA - Toxicology and Risk Assessment PHS - Pharmacokinetics & Human Studies (tot 2013 daarna KFP) · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

8 Dose-dependent prebiotic effect of lactulose in a computer-controlled in vitro model of the human large intestine
article 2017    
Author: Bothe, M.K. · Maathuis, A.J.H. · Bellmann, S. · Vossen, J.M.B.M. van der · Berressem, D. · Koehler, A. · Schwejda-Guettes, S. · Gaigg, B. · Kuchinka-Koch, A. · Stover, J.F.
Keywords: Biology · Ammonia · Anaerostipes · Bifidobacteria · Butyrate · Lactobacilli · Lactulose · Microbial fermentation · Biomedical Innovation · Healthy Living · Life Triskelion BV · MSB - Microbiology and Systems Biology ADME - ADME/DMPK · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[PDF] [Abstract]

9 Comprehensive analysis of the intracellular metabolism of antiretroviral nucleosides and nucleotides using liquid chromatography-tandem mass spectrometry and method improvement by using ultra performance liquid chromatography
article 2011    
Author: Coulier, L. · Gerritsen, H. · Kampen, J.J.A. van · Reedijk, M.L. · Luider, T.M. · Osterhaus, A.D.M.E. · Gruters, R.A. · Brüll, L.
Keywords: Nutrition · Antiretroviral drugs · HIV · Ion-pair LC-MS/MS · NRTI · Phosphorylated metabolites · UPLC · Life Triskelion BV · QS - Quality & Safety AR - Analytical Research · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

10 Interlaboratory evaluation of a cow's milk allergy mouse model to assess the allergenicity of hydrolysed cow's milk based infant formulas
article 2013    
Author: Esch, B.C.A.M. van · Bilsen, J.H.M. van · Jeurink, P.V. · Garssen, J. · Penninks, A.H. · Smit, J.J. · Pieters, R.H.H. · Knippels, L.M.J.
Keywords: Biology · Allergenicity · Cow's milk allergy · Hydrolysed infant formulas · Mouse model · Safety · Sensitization · Food and Nutrition · Healthy Living · Life Triskelion BV · QS - Quality & Safety RAPID - Risk Analysis for Products in Development · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

11 The Göttingen minipig® as an alternative non-rodent species for immunogenicity testing: A demonstrator study using the IL-1 receptor antagonist anakinra
article 2013    
Author: Mierlo, G.J.D. van · Cnubben, N.H.P. · Kuper, C.F. · Wolthoorn, J. · Meeteren-Kreikamp, A.P. van · Nagtegaal, M.M. · Doornbos, R. · Ganderup, N.-C. · Penninks, A.H.
Keywords: Biology · Anakinra · Anti-drug antibodies · Immunogenicity · Minipigs · Pharmacokinetics · Biomedical Innovation · Healthy Living · Life Triskelion BV · QS - Quality & Safety TARA - Toxicology and Risk Assessment · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

12 Oxazolone (OXA) is a respiratory allergen in Brown Norway rats
article 2011    
Author: Kuper, C.F. · Radonjic, M. · Triel, J. van · Stierum, R. · Groot, R.J. de · Arts, J.H.E.
Keywords: Toxicology · 4-Ethoxymethylene-2-phenyl-2-oxazoline-5-one · Allergic laryngitis · Gene expression · GZMB · Neutrophils · SELP · Life Triskelion BV · QS - Quality & Safety TAP - Toxicology and Applied Pharmacology · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

13 Metabolite profiling of small cerebrospinal fluid sample volumes with gas chromatography-mass spectrometry: Application to a rat model of multiple sclerosis
article 2013    
Author: Coulier, L. · Muilwijk, B. · Bijlsma, S. · Noga, M. · Tienstra, M. · Attali, A. · Aken, H. van · Suidgeest, E. · Tuinstra, T. · Luider, T.M. · Hankemeier, T. · Bobeldijk, I.
Keywords: Health · Animal model · Cerebrospinal fluid · EAE model · GC-MS · Metabolomics · Multiple sclerosis · Healthy for Life · Healthy Living · Life Triskelion BV · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

14 Pre-processing liquid chromatography/high-resolution mass spectrometry data: Extracting pure mass spectra by deconvolution from the invariance of isotopic distribution
article 2013    
Author: Krishnan, S. · Verheij, E.E.R. · Bas, R.C. · Hendriks, M.W.B. · Hankemeier, T. · Thissen, U. · Coulier, L.
Keywords: Biology · Biomedical Innovation · Healthy Living · Life Life Triskelion BV · MSB - Microbiology and Systems Biology QS - Quality & Safety TARA - Toxicology and Risk Assessment · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

15 Nasal passages of Göttingen minipigs from the neonatal period to young adult
article 2012    
Author: Kuper, C.F. · Ernst, H. · Oostrum, L.C.M. van · Rittinghausen, S. · Penninks, A.H. · Ganderup, N.-C. · Wolterbeek, A.P.M.
Keywords: inhalation · juvenile development · minipig · NALT · nasal levels · olfactory bulb · vomeronasal organ · Healthy for Life · Healthy Living · Life Triskelion BV · QS - Quality & Safety TAP - Toxicology and Applied Pharmacology · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

16 The determination of budesonide and fluticasone in human sputum samples collected from COPD patients using LC-MS/MS
article 2012    
Author: Buscher, B.A.P. · Jägfeldt, H. · Sandman, H. · Brust-van Schaik, R. · Schaik, F. van · Brüll, L.P.
Keywords: Biology · Bioanalysis · HPLC · Mass spectrometry · Sample pre-treatment · Sputum · Validation · Healthy Living · Life Triskelion BV · QS - Quality & Safety TAP - Toxicology and Applied Pharmacology · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

17 Management of Undescended Testis : A Decision Analysis
article 2013    
Author: Akker-van Marle, M.E. van den · Kamphuis, M. · Gameren-Oosterom, H.B.M. van · Pierik, F.H. · Kievit, J.
Keywords: Health · Cryptorchidism · Decision analysis · Orchidopexy · Biomedical Innovation · Healthy Living · Human Earth & Environment Triskelion BV · ARF - Analytical Research (Food) CH - Child Health UES - Urban Environment & Safety · BSS - Behavioural and Societal Sciences EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

18 Predicting blood:air partition coefficients using basic physicochemical properties
article 2012    
Author: Buist, H.E. · Wit-Bos, L. de · Bouwman, T. · Vaes, W.H.J.
Keywords: Biology · Blood:air partition coefficient · Human · Inhalation · PBPK · QPPR · Rat · Volatile organic chemicals · Biomedical Innovation · Healthy Living · Life Triskelion BV · QS - Quality & Safety CRA - Chemical Risk Analysis · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

19 The determination of exogenous formaldehyde in blood of rats during and after inhalation exposure
article 2013    
Author: Kleinnijenhuis, A.J. · Staal, Y.C.M. · Duistermaat, E. · Engel, R. · Woutersen, R.A.
Keywords: Health · 13C-formaldehyde · HPLC-MS analysis in blood · Inhalation study · Stable isotope labeling · Biomedical Innovation · Healthy Living · Life Triskelion BV · QS - Quality & Safety RAPID - Risk Analysis for Products in Development ARPC - Analytical Research (Pharm & Chemistry) TARA - Toxicology and Risk Assessment · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

20 Quantitative metabolomics based on gas chromatography mass spectrometry: Status and perspectives
article 2011    
Author: Koek, M.M. · Jellema, R.H. · Greef, J. van der · Tas, A.C. · Hankemeier, T.
Keywords: Nutrition Biology · Data preprocessing · Gas chromatography mass spectrometry · Method validation · Quality control · Quantitative metabolomics · analytic method · derivatization · information processing · mass fragmentography · metabolomics · nonhuman · process optimization · quality control · quantitative analysis · review · silylation · validation study · Life Triskelion BV · MSB - Microbiology and Systems Biology AR - Analytical Research · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 24 found. Next | Sort by date