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Showing 1 to 17 of 17 found. | Sort by date

1 Moderate cholecalciferol supplementation depresses intestinal calcium absorption in growing dogs
article 2002    
Author: Tryfonidou, M.A. · Stevenhagen, J.J. · Bemd, G.J.C.M. van den · Oosterlaken-Dijksterhuis, M.A. · Deluca, H.F. · Mol, J.A. · Brom, W.E. van den · Leeuwen, J.P.T.M. van · Hazewinkel, H.A.W.
Keywords: Nutrition · Animals · Calcitriol · Calcium · Calcium Radioisotopes · Calcium, Dietary · Cholecalciferol · Cytochrome P-450 Enzyme System · Dogs · Down-Regulation · Female · Gene Expression Regulation, Enzymologic · Intestinal Absorption · Intestines · Kidney · Male · Metabolic Clearance Rate · Models, Animal · Phosphates · Receptors, Calcitriol · Steroid Hydroxylases · Animalia · Canis familiaris
[Abstract]

2 Expression of heterologous genes in Schizophyllum commune is often hampered by the formation of truncated transcripts
article 1998    
Author: Schuren, F.H.J. · Wessels, J.G.H.
Keywords: Nutrition · Basidiomycete fungus · Heterologous gene expression · Schizophyllum commune · Transcription termination · Aminoglycoside · Beta glucuronidase · Hygromycin b · Messenger rna · Phleomycin · Phosphotransferase · Antibiotic resistance · Fungal genetics · Molecular cloning · Nonhuman · Priority journal · Schizophyllum commune · Base Sequence · beta-Galactosidase · DNA, Fungal · Gene Expression Regulation, Enzymologic · Gene Expression Regulation, Fungal · Glucuronidase · Glyceraldehyde-3-Phosphate Dehydrogenases · Kanamycin Kinase · Molecular Sequence Data · Phosphotransferases (Alcohol Group Acceptor) · Schizophyllum · Fungi · Schizophyllum commune
[Abstract]

3 Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: Implications for collagen cross-linking and treatment of fibrosis
article 2005    
Author: Zuurmond, A.M. · Slot van der-Verhoeven, A.J. · Dura, E.A. van · Groot, J. de · Bank, R.A.
Keywords: Biology · Biomedical Research · Lysyl hydroxylase · Pyridinoline cross-links · Messenger RNA · Procollagen lysine 2 oxoglutarate 5 dioxygenase · Pyridinoline · Concentration response · Controlled study · Dose time effect relation · Drug activity · Drug inhibition · Drug sensitivity · Enzyme specificity · Enzyme substrate · Extracellular matrix · Fibroblast culture · Human cell · Protein cross linking · Protein structure · Skin fibrosis · 2-Aminoadipic Acid · Cells, Cultured · Chromatography, High Pressure Liquid · Collagen · Fibrosis · Gene Expression Regulation, Enzymologic · Humans · Hydroxylation · Minoxidil · Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase
[Abstract]

4 Dynamics of insulin signalling in liver during hyperinsulinemic euglycaemic clamp conditions in vivo and the effects of high-fat feeding in male mice
article 2007    
Author: Korsheninnikova, E. · Voshol, P.J. · Baan, B. · Zon, G.C.M. van der · Havekes, L.M. · Romijn, J.A. · Maassen, J.A. · Ouwens, D.M.
Keywords: Biology · Biomedical Research · Hepatic glucose production · High-fat diet · Insulin resistance · Insulin signalling · Liver · glucose · insulin · insulin receptor · phosphatidylinositol 3 kinase · protein kinase B · animal · article · blood · C57BL mouse · drug effect · fat intake · gene expression regulation · glucose clamp technique · hyperinsulinism · liver · male · metabolism · mouse · signal transduction · 1-Phosphatidylinositol 3-Kinase · Animals · Dietary Fats · Gene Expression Regulation, Enzymologic · Glucose · Glucose Clamp Technique · Hyperinsulinism · Insulin · Liver · Male · Mice · Mice, Inbred C57BL · Proto-Oncogene Proteins c-akt · Receptor, Insulin · Signal Transduction · Mus
[Abstract]

5 Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase gene transcription
article 1995    
Author: Twisk, J. · Hoekman, M.F.M. · Lehmann, E.M. · Meijer, P. · Mager, W.H. · Princen, H.M.G.
Keywords: Biology · cholesterol 7alpha monooxygenase · insulin · oxygenase · sterol 27 hydroxylase · unclassified drug · animal cell · article · bile acid synthesis · controlled study · down regulation · enzyme activity · gene expression regulation · hormone action · liver cell culture · nonhuman · transcription regulation · Animal · Bile Acids and Salts · Cells, Cultured · Chloramphenicol O-Acetyltransferase · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 Enzyme System · Down-Regulation · Gene Expression Regulation, Enzymologic · Insulin · Liver · Male · Membrane Glycoproteins · Nuclear Proteins · Rats · Rats, Wistar · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Transcription, Genetic · Transfection
[Abstract]

6 The untranslated leader sequence of the barley lipoxygenase 1 (Lox1) gene confers embryo-specific expression
article 1998    
Author: Rouster, J. · Mechelen J. van · Cameron-Mills, V.
Keywords: Nutrition · Aleurone · Assay · Chimeric gene · Germination · Lipoxygenase i · Methyl jasmonate · Plant development · Plant genetics · Quantitative genetics · Regulatory sequence · Transcription regulation · Acetic Acids · Base Sequence · Cyclopentanes · DNA, Plant · Enhancer Elements (Genetics) · Gene Expression Regulation, Developmental · Gene Expression Regulation, Enzymologic · Gene Expression Regulation, Plant · Genes, Plant · Genes, Reporter · Germination · Glucuronidase · Hordeum · Lipoxygenase · Molecular Sequence Data · Mutation · Plant Growth Regulators · Plants, Genetically Modified · Embryophyta · Hordeum vulgare subsp. vulgare
[Abstract]

7 Elevated formation of pyridinoline cross-links by profibrotic cytokines is associated with enhanced lysyl hydroxylase 2b levels
article 2005    
Author: Slot, A.J. van der · Dura, E.A. van · Wit, E.C. de · Groot, J. de · Huizinga, T.W.J. · Bank, R.A. · Zuurmond, A.M.
Keywords: Lysyl hydroxylase 2b · Pyridinoline · TGF-β · Activin A · Protein lysine 6 oxidase · Transforming growth factor beta · Tumor necrosis factor alpha · Controlled study · Cross linking · Human cell · Protein expression · Skin fibroblast · Skin fibrosis · Upregulation · Activins · Amino Acids · Cells, Cultured · Collagen Type I · Cross-Linking Reagents · Cytokines · Fibroblasts · Fibrosis · Gene Expression Regulation, Enzymologic · Humans · Inhibin-beta Subunits · Interleukin-4 · Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase · Protein Isoforms · RNA, Messenger · Skin · Time Factors · Transforming Growth Factor beta · Tumor Necrosis Factor-alpha · Up-Regulation
[Abstract]

8 The role of the Aspergillus niger furin-type protease gene in processing of fungal proproteins and fusion proteins: Evidence for alternative processing of recombinant (fusion-) proteins
article 2003    
Author: Punt, P.J. · Drint-Kuijvenhoven, A. · Lokman, B.C. · Spencer, J.A. · Jeenes, D. · Archer, D.A. · Hondel, C.A.M.J.J. van den
Keywords: Biology · Biotechnology · Filamentous fungi · Fusion-proteins · Protease · Protein processing · Protein secretion · Secretion carrier · Biotechnology · Genes · Growth kinetics · Mutagenesis · Proteins · Cleavage sites · Genetic engineering · arginine · aspergillopepsin · fungal protein · furin · glucan 1,4 alpha glucosidase · hybrid protein · lysine · protein precursor · proteinase · recombinant protein · unclassified drug · allele · amino acid composition · article · Aspergillus niger · controlled study · fungal gene · fungal strain · fungus mutant · gene deletion · gene disruption · gene function · genetic code · genetic recombination · molecular cloning · nonhuman · nucleotide sequence · priority journal · protein degradation · protein processing · wild type · Aspergillus niger · Endopeptidases · Fungal Proteins · Furin · Gene Expression Regulation, Enzymologic · Gene Expression Regulation, Fungal · Protein Processing, Post-Translational · Recombinant Fusion Proteins · Trans-Activation (Genetics) · Aspergillus · Aspergillus niger · Fungi
[Abstract]

9 Endoplasmic reticulum stress leads to the selective transcriptional downregulation of the glucoamylase gene in Aspergillus niger
article 2004    
Author: Al-Sheikh, H. · Watson, A.J. · Lacey, G.A. · Punt, P.J. · MacKenzie, D.A. · Jeenes, D.J. · Pakula, T. · Penttilä, M. · Alcocer, M.J.C. · Archer, D.B.
Keywords: Biology · Biotechnology · actin · chaperone · dithiothreitol · gamma actin · glucan 1,4 alpha glucosidase · glyceraldehyde 3 phosphate dehydrogenase · protein HacA · unclassified drug · article · Aspergillus niger · bipa gene · down regulation · endoplasmic reticulum · fungal cell · fungal gene · fungal strain · gene expression · gene induction · genetic code · glaa gene · nonhuman · pdiA gene · priority journal · promoter region · protein folding · protein secretion · RNA splicing · RNA stability · stress · transcription regulation · upregulation · Aspergillus niger · Dithiothreitol · Down-Regulation · Endoplasmic Reticulum · Fungal Proteins · Gene Expression Regulation, Enzymologic · Gene Expression Regulation, Fungal · Glucan 1,4-alpha-Glucosidase · HSP70 Heat-Shock Proteins · Oligonucleotides, Antisense · Promoter Regions (Genetics) · Protein Folding · Transcription, Genetic · Aspergillus · Aspergillus niger · Fungi
[Abstract]

10 The cell wall stress response in Aspergillus niger involves increased expression of the glutamine: Fructose-6-phosphate amidotransferase-encoding gene (gfaA) and increased deposition of chitin in the cell wall
article 2004    
Author: Ram, A.F.J. · Arentshorst, M. · Damveld, R.A. · Kuyk, P.A. van · Klis, F.M. · Hondel, C.A.M.J.J. van den
Keywords: Biology · Biotechnology · chitin · glucosamine · glutamine fructose 6 phosphate aminotransferase · article · Aspergillus niger · cell wall · controlled study · culture medium · deletion mutant · food spoilage · fungal cell culture · fungal strain · Fusarium oxysporum · gene disruption · genetic code · genetic transcription · molecular cloning · nonhuman · nucleotide sequence · Penicillium chrysogenum · priority journal · protein expression · protein metabolism · protein synthesis · stress · Amino Acid Sequence · Aspergillus niger · Cell Wall · Chitin · Gene Expression Regulation, Enzymologic · Gene Expression Regulation, Fungal · Glucosamine · Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing) · Molecular Sequence Data · Phylogeny · Aspergillus · Aspergillus niger · Fungi · Fusarium · Fusarium oxysporum · Penicillium · Penicillium chrysogenum · Saccharomyces · Saccharomyces cerevisiae
[Abstract]

11 Endothelium specific matrilysin (MMP-7) expression in human cancers
article 2008    
Author: Sier, C.F.M. · Hawinkels, L.J.A.C. · Zijlmans, H.J.M.A.A. · Zuidwijk, K. · Jonge de · Muller, E.S.M. · Ferreira, V. · Hanemaaijer, R. · Mulder-Stapel, A.A. · Kenter, G.G. · Verspaget, H.W. · Gorter, A.
Keywords: Health · Physiological Sciences · Angiogenesis · Breast · Carcinoma · Cervix · Colon · Matrix metalloproteinase · Prostate · Stomach · CD34 antigen · endoglin · matrilysin · vasculotropin · adult · aged · angiogenesis · antigen expression · article · cancer cell · cancer growth · cancer patient · cancer survival · endothelium cell · female · human · human cell · human tissue · immunohistochemistry · in vitro study · major clinical study · malignant neoplastic disease · priority journal · protein expression · reverse transcription polymerase chain reaction · tumor vascularization · uterine cervix cancer · Carcinoma · Cell Line, Tumor · Endothelium · Female · Gene Expression Regulation, Enzymologic · Gene Expression Regulation, Neoplastic · Humans · Matrix Metalloproteinase 7 · Neoplasm Invasiveness · Neovascularization, Pathologic · Spheroids, Cellular · Time Factors · Tissue Distribution · Umbilical Veins · Uterine Cervical Neoplasms
[Abstract]

12 Regulation of expression of the Aspergillus niger benzoate para-hydroxylase cytochrome P450 system
article 2000    
Author: Brink, J.M. van den · Punt, P.J. · Gorcom, R.F.M. van · Hondel, C.A.M.J.J. van den
Keywords: Nutrition · Aspergillus niger · Benzoate · Cytochrome P450 · Post-transcriptional regulation · Benzoic acid · Cytochrome P450 · Cytochrome P450 reductase · Oxygenase · Aspergillus niger · DNA responsive element · Enzyme analysis · Enzyme regulation · Gene expression regulation · Gene function · Gene induction · Genetic transcription · Hydroxylation · Nonhuman · Nucleotide sequence · Priority journal · Promoter region · Protein induction · Amino Acid Sequence · Aspergillus niger · Base Sequence · Benzoates · Enzyme Induction · Gene Expression Regulation, Bacterial · Gene Expression Regulation, Enzymologic · Mixed Function Oxygenases · Molecular Sequence Data · NADH, NADPH Oxidoreductases · NADPH-Ferrihemoprotein Reductase · Oxygenases · Promoter Regions (Genetics) · Recombinant Fusion Proteins · Restriction Mapping · Sequence Alignment · Sequence Homology, Amino Acid · Transcription, Genetic · Aspergillus niger · Eukaryota · Fungi
[Abstract]

13 Heterogeneous expression of cholesterol 7α-hydroxylase and sterol 27- hydroxylase genes in the rat liver lobulus
article 1995    
Author: Twisk, J. · Hoekman, M.F.M. · Mager, W.H. · Moorman, A.F.M. · Boer, P.A.J. de · Scheja, L. · Princen, H.M.G. · Gebhardt, R.
Keywords: Health · 3 hydroxy 3 methylglutaryl coenzyme a · alanine aminotransferase · cholesterol 7alpha monooxygenase · colestipol · glutamate ammonia ligase · glyceraldehyde 3 phosphate dehydrogenase · messenger rna · pyruvate kinase · sterol 27 hydroxylase · unclassified drug · animal cell · animal experiment · bile acid synthesis · controlled study · enterohepatic circulation · enzyme isolation · enzyme localization · gene expression · in situ hybridization · liver metabolism · sterol analysis · Animal · Biological Markers · Blotting, Northern · Cell Separation · Cholesterol 7-alpha-Hydroxylase · Colestipol · Cytochrome P-450 Enzyme System · Gene Expression Regulation, Enzymologic · In Situ Hybridization · Liver · Male · Rats · Rats, Sprague-Dawley · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Tissue Distribution · Transcription, Genetic
[Abstract]

14 Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes
article 1995    
Author: Twisk, J. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Biology · bile acid · chenodeoxycholic acid · cholesterol 7alpha monooxygenase · cholic acid · deoxycholic acid · lithocholic acid · messenger rna · oxygenase · sterol · taurocholic acid · animal cell · article · bile acid synthesis · cholesterol metabolism · controlled study · enzyme inhibition · gene repression · liver cell culture · nonhuman · priority journal · rat · transcription regulation · Adenosine Triphosphate · Animal · Bile Acids and Salts · Cells, Cultured · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Down-Regulation · Gene Expression Regulation, Enzymologic · Liver · Male · Mitochondria · Oxidoreductases · Rats · Rats, Wistar · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Taurocholic Acid · Transcription, Genetic
[Abstract]

15 Cholesterol 7α-hydroxylase deficiency in mice on an APOE*3-Leiden background increases hepatic ABCA1 mRNA expression and HDL-cholesterol
article 2006    
Author: Post, S.M. · Groenendijk, M. · Hoogt, C.C. van der · Fievet, C. · Luc, G. · Hoekstra, M. · Princen, H.M.G. · Staels, B. · Rensen, P.C.N.
Keywords: Health · Biomedical Research · High-density lipoprotein · ABC transporter A1 · High density lipoprotein cholesterol · Intermediate density lipoprotein · Low density lipoprotein · Messenger RNA · Phosphatidylcholine sterol acyltransferase · Very low density lipoprotein · Bile acid · Phospholipid transfer protein · Phospholipid transfer protein, mouse · Animal experiment · Animal tissue · Bile acid synthesis · Biosynthesis · Catabolism · Cholesterol blood level · Cholesterol metabolism · cholesterol transport · Conhuman · Protein expression · Transgenic mouse · Genetics · Metabolism · Mouse · Mouse mutant · Physiology · Animals · Apolipoprotein E3 · ATP-Binding Cassette Transporters · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol, HDL · Female · Gene Expression Regulation · Gene Expression Regulation, Enzymologic · Humans · Liver · Mice · Mice, Knockout · Mice, Transgenic · Phosphatidylcholine-Sterol O-Acyltransferase · Phospholipid Transfer Proteins · RNA, Messenger
[Abstract]

16 Translation controls the expression level of a chimaeric reporter gene
article 1992    
Author: Hensgens, L.A.M. · Fornerod, M.W.J. · Rueb, S. · Winkler, A.A. · Veen, S. van der · Schilperoort, R.A.
Keywords: β-D-glucuronidase · Gene expression · Initiation of translation · Mannopine synthase promoter · Beta glucuronidase · Chimeric protein · DNA · Mannopine synthase · Oligodeoxyribonucleotide · Agrobacterium tumefaciens · Biosynthesis · Enzymology · Gene expression regulation · Genetic transcription · Genetics · Isolation and purification · Metabolism · Molecular genetics · Nucleotide sequence · Plant · Promoter region · Estriction mapping · RNA translation · Tobacco · Transgenic plant · Western blotting · Agrobacterium tumefaciens · Base Sequence · Blotting, Southern · Blotting, Western · Chimeric Proteins · DNA · Gene Expression Regulation, Enzymologic · Glucuronidase · Hydro-Lyases · Molecular Sequence Data · Oligodeoxyribonucleotides · Plants, Genetically Modified · Plants, Toxic · Promoter Regions (Genetics) · Reading Frames · Restriction Mapping · RNA, Messenger · Support, Non-U.S. Gov't · Tobacco · Transcription, Genetic · Translation, Genetic
[Abstract]

17 Doxycycline therapy for abdominal aneurysm: Improved proteolytic balance through reduced neutrophil content
article 2009    
Author: Abdul-Hussien, H. · Hanemaaijer, R. · Verheijen, J.H. · Bockel, J.H. van · Geelkerken, R.H. · Lindeman, J.H.N.
Keywords: Biology · Biomedical Research · antihypertensive agent · antithrombocytic agent · cystatin C · cysteine proteinase · doxycycline · gelatinase B · hydroxymethylglutaryl coenzyme A reductase inhibitor · messenger RNA · neutrophil collagenase · stromelysin · tissue inhibitor of metalloproteinase 1 · abdominal aorta aneurysm · adult · aged · aorta wall · article · clinical article · clinical trial · controlled clinical trial · controlled study · dose response · drug effect · drug megadose · drug tolerability · enzyme activity · enzyme assay · female · gene expression · human · human tissue · immunohistochemistry · low drug dose · male · neutrophil · polymerase chain reaction · priority journal · protein degradation · quantitative analysis · randomized controlled trial · treatment duration · Western blotting · Aged · Aged, 80 and over · Aorta, Abdominal · Aortic Aneurysm, Abdominal · Cardiovascular Agents · Cystatin C · Cysteine Endopeptidases · Dose-Response Relationship, Drug · Doxycycline · Female · Gene Expression Regulation, Enzymologic · Humans · Male · Matrix Metalloproteinases · Middle Aged · Neutrophil Infiltration · Neutrophils · Prospective Studies · Protease Inhibitors · RNA, Messenger · Time Factors · Tissue Inhibitor of Metalloproteinase-1 · Treatment Outcome · Vascular Surgical Procedures
[Abstract]

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Showing 1 to 17 of 17 found. | Sort by date