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1 Immunohistochemical analysis of the plasminogen activation system and the matrix metalloproteinases in normal and atherosclerotic human vessels
article 1999    
Author: Wijnberg, M.J. · Slomp, J. · Verheijen, J.H.
Keywords: matrix metalloproteinase · plasminogen · adult · aged · atherosclerosis · controlled study · enzyme activation · enzyme localization · female · human · human tissue · immunohistochemistry · male · plasminogen activation · priority journal · review · vascular smooth muscle
[Abstract]

2 Highly increased levels of active stromelysin in rheumatoid synovial fluid determined by a selective fluorogenic assay
article 1997    
Author: Beekman, B. · El, B. van · Drijfhout, J.W. · Ronday, H.K. · TeKoppele, J.M.
Keywords: Biomedical Research · Fluorogenic substrate · MMP-3 · Rheumatoid arthritis · Stromelysin · Synovial fluid · Stromelysin · Controlled study · Enzyme activity · Enzyme assay · Human tissue · Priority journal · Rheumatoid arthritis · Synovial fluid · Technique · Arthritis, Rheumatoid · Biological Assay · Biological Markers · Fluorescence · Humans · Matrix Metalloproteinase 3
[PDF] [Abstract]

3 Effect of various levels of selenium in wheat and meat on blood Se status indices and on Se balance in Dutch men
article 1991    
Author: Torre H.W.van der · Dokkum, W. van · Schaafsma, G. · Wedel, M. · Ockhuizen, T.
Keywords: Dutch men · Selenium balance · Selenium bioavailability · Wheat · Human tissue · Nutrition · Thrombocyte · Urinalysis · Wheat · Adult · Biological Availability · Blood Platelets · Case Report · Diet · Erythrocytes · Glutathione Peroxidase · Human · Male · Meat · Selenium · Time Factors · Triticum · Triticum aestivum
[PDF] [Abstract]

4 Mechanical properties of the collagen network in human articular cartilage as measured by osmotic stress technique
article 1998    
Author: Basser, P.J. · Schneiderman, R. · Bank, R.A. · Wachtel, E. · Maroudas, A.
Keywords: Health · Collagen network · Connective tissue · Degeneration · Human cartilage · Hydration · Swelling · Tension · Collagen · Articular cartilage · Biomechanics · Calculation · Human · Human tissue · Hydration · Osmotic stress · Priority journal · Tensile strength · Cartilage, Articular · Collagen · Extracellular Matrix · Humans · Osmotic Pressure · Osteoarthritis · Polyethylene Glycols · Proteoglycans · Trypsin · Water
[Abstract]

5 Immunochemical detection of sulfur mustard adducts with keratins in the stratum corneum of human skin
article 2002    
Author: Schans, G.P. van der · Noort, D. · Mars-Groenendijk, R.H. · Fidder, A. · Chau, L.F. · Jong, L.P.A. de · Benschop, H.P.
Keywords: Asparagine · Glutamine · Keratin · Monoclonal antibody · Mustard gas · Article · Chemical warfare · Controlled study · Environmental exposure · Human · Human tissue · Immunochemistry · Immunofluorescence microscopy · Pollutant · Protein binding · Quantitative assay · Skin test · Stratum corneum · Animals · Antibodies, Monoclonal · Antibody Specificity · Enzyme-Linked Immunosorbent Assay · Epidermis · Fluorescent Antibody Technique, Indirect · Haptens · Humans · Immunohistochemistry · Keratins · Mice · Microscopy, Fluorescence · Mustard Gas
[Abstract]

6 Brown adipose tissue volume in healthy lean south Asian adults compared with white Caucasians: A prospective, case-controlled observational study
article 2014    
Author: Bakker, L.E.H. · Boon, M.R. · Linden, R.A.D. van der · Arias-Bouda, L.P. · Klinken, J.B. van · Smit, F. · Verberne, H.J. · Jukema, J.W. · Tamsma, J.T. · Havekes, L.M. · Marken Lichtenbelt, W.D. van · Jazet, I.M. · Rensen, P.C.N.
Keywords: Biology · Fatty acid · Fluorodeoxyglucose f 18 · Glucose · Adult · Analytical parameters · Brown adipose tissue · Case control study · Caucasian · Computer assisted tomography · Controlled study · Energy metabolism · Ethnic difference · Ethnic group · Ethnicity · Human · Human tissue · Incidence · Non insulin dependent diabetes mellitus · Observational study · Outcome assessment · Prospective study · South Asian · Tissue volume · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

7 Pentosidine accumulates in the aging vitreous body: A gender effect
article 2009    
Author: Deemter, M. van · Ponsioen, T.L. · Bank, R.A. · Snabel, J.M.M. · Worp, R.J. van der · Hooymans, J.M.M. · Los, L.I.
Keywords: Biology · Biomedical Research · advanced glycation end product · aging · collagen · gender · oxidative stress · pentosidine · vitreous · advanced glycation end product · collagen · pentosidine · adolescent · adult · aged · aging · article · bioaccumulation · collagen degradation · controlled study · correlation analysis · female · human · human tissue · male · oxidative stress · priority journal · sex difference · vitreous body
[Abstract]

8 Distinct defects in collagen microarchitecture underlie vessel-wall failure in advanced abdominal aneurysms and aneurysms in Marfan syndrome
article 2010    
Author: Lindeman, J.H.N. · Ashcroft, B.A. · Beenakker, J.-W.M. · Es, M. van · Koekkoek, N.B.R. · Prins, F.A. · Tielemans, J.F. · Abdul-Hussien, H. · Bank, R.A. · Oosterkamp, T.H.
Keywords: Biology · Biomedical Research · collagen · abdominal aorta aneurysm · adult · aged · article · atomic force microscopy · clinical article · collagen defect · controlled study · human · human tissue · Marfan syndrome · priority journal · protein analysis · protein structure · Aged · Aorta, Abdominal · Aortic Aneurysm, Abdominal · Arteries · Collagen · Humans · Hydroxyproline · Marfan Syndrome · Microscopy, Confocal · Middle Aged · Proline
[Abstract]

9 Analyses of human colonic mucus obtained by an in vivo sampling technique
article 2009    
Author: Hamer, H.M. · Jonkers, D.M.A.E. · Loof, A. · Houtvin, S.A.L.W. van · Troost, F.J. · Venema, K. · Kodde, A. · Koek, G.H. · Schipper, R.G. · Heerde, W.L. van · Brummer, R.J.
Keywords: Biology Health · Biomedical Research · Colon · Mucus · Proteomics · Secretory IgA · fucose · galactosamine · galactose · glucosamine · glycoprotein · Immunoglobulin A · Monosaccharide · Mucin · Oligosaccharide · Sialic acid · Adult · Anion exchange chromatography · Colon mucosa · Colon mucus · Concentration (parameters) · Cytology · Female · Human · Human tissue · In vivo study · Intestine epithelium · Male · Mucus · Normal human · Priority journal · Protein analysis · Proteomics · Sampling · Sigmoidoscopy · Surface enhanced laser desorption ionization time of flight mass spectrometry · Volunteer
[Abstract]

10 Degenerated and healthy cartilage are equally vulnerable to blood-induced damage
article 2008    
Author: Jansen, N.W.D. · Roosendaal, G. · Bijlsma, J.W.J. · Groot, J. de · Theobald, M. · Lafeber, F.P.J.G.
Keywords: Health · Matrix metalloproteinase · Proteoglycan · Aged · Article · Blood · Cartilage cell · Cartilage degeneration · Controlled study · Enzyme activity · Female · Hemarthrosis · Human · Human tissue · Male · Osteoarthritis · Priority journal · Proteoglycan synthesis · Aged · Blood · Cartilage, Articular · Chondrocytes · Female · Hemarthrosis · Humans · Male · Matrix Metalloproteinases · Middle Aged · Osteoarthritis · Proteoglycans · Tissue Culture Techniques · Food and Nutrition · Healthy Living
[Abstract]

11 Establishment of a general NAFLD scoring system for rodent models and comparison to human liver pathology
article 2014    
Author: Liang, W. · Menke, A.L. · Driessen, A. · Koek, G.H. · Lindeman, J.H. · Stoop, R. · Havekes, L.M. · Kleemann., R. · Hoek, A.M. van den
Keywords: Biology · Adult · Animal experiment · Animal model · Clinical article · Controlled study · Female · Hepatitis · Histopathology · Human · Human tissue · Human versus animal comparison · Liver biopsy · Liver fibrosis · Liver hypertrophy · Macrovesicular steatosis · Male · Microvesicular steatosis · Nonalcoholic fatty liver · Nonhuman · Process development · Reproducibility · Scoring system · Steatosis · Validation process · Rodentia · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

12 Mass spectrometric identification of isocyanate-induced modifications of keratins in human skin
article 2015    
Author: Hulst, A.G. · Verstappen, D.R.W. · Riet-van Oeveren, D. van der · Vermeulen, N.P.E. · Noort, D.
Keywords: Adducts · Biomarkers · Exposure assessment · Isocyanates · Keratin · Skin · 2 methacryloyloxethyl isocyanate · 2 nitrophenylisocyanate · 2,6 toluene diisocyanate · 4 bromophenylisocyanate · Allylisocyanate · Biological marker · Elastin · Isocyanic acid derivative · Keratin · Lysine · Methylene diphenyl diisocyanate · Phenethylisocyanate · Pronase · Unclassified drug · Antigenicity · Asthma · Callus · Exposure · Human · Human tissue · Mass spectrometry · Protein analysis · Protein isolation · Protein modification · Skin sensitization · Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[Abstract]

13 Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer
article 2007    
Author: Kubben, F.J.G.M. · Sier, C.F.M. · Hawinkels, L.J.A.C. · Tschesche, H. · Duijn, W. van · Zuidwijk, K. · Reijden, J.J. van der · Hanemaaijer, R. · Griffioen, G. · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biology · Biomedical Research · Activity assay · Cancer · Metalloproteinase · Prognosis · gelatinase B · lipocalin · matrix metalloproteinase inhibitor · tissue inhibitor of metalloproteinase 1 · adult · aged · article · autolysis · cancer survival · disease classification · enzyme activity · enzyme degradation · epithelium cell · female · human · human tissue · immunohistochemistry · major clinical study · male · multivariate analysis · priority journal · protein function · stomach cancer · tumor · univariate analysis · world health organization
[Abstract]

14 Kinetic characteristics of acidic and alkaline ceramidase in human epidermis
article 2007    
Author: Houben, E. · Uchida, Y. · Nieuwenhuizen, W.F. · Paepe, K. de · Vanhaecke, T. · Holleran, W.M. · Rogiers, V.
Keywords: Nutrition · Food technology · Ceramidase · Epidermis · Kinetic parameters · acylsphingosine deacylase · enzyme inhibitor · ethanolamine derivative · isoenzyme · adult · article · enzyme activity · enzyme analysis · enzyme assay · enzyme inhibition · enzyme kinetics · enzyme substrate · enzymology · epidermis · female · human · human tissue · isoenzyme analysis · isotope labeling · normal human · nucleotide sequence · priority journal · zymography · Adult · Amidohydrolases · Enzyme Repression · Epidermis · Female · Humans · Hydrogen-Ion Concentration · Isoenzymes · Kinetics · Middle Aged · Skin Absorption
[Abstract]

15 Trans unsaturated fatty acids in plasma phospholipids and coronary heart disease: A case-control study
article 1996    
Author: Vijver, L.P.L. van de · Poppel, G. van · Houwelingen, A. van · Kruyssen, D.A.C.M. · Hornstra, G.
Keywords: Coronary atherosclerosis · Phospholipids · Trans Fatty acid · high density lipoprotein · low density lipoprotein · adult · aged · article · controlled study · diet · human · human tissue · ischemic heart disease · lipid analysis · major clinical study · multicenter study · priority journal · risk factor · Aged · Case-Control Studies · Coronary Angiography · Coronary Arteriosclerosis · Coronary Disease · Dietary Fats · Fatty Acids, Unsaturated · Female · Food Habits · Humans · Hypertension · Male · Multivariate Analysis · Phospholipids · Risk Factors · Smoking
[Abstract]

16 Retrospective detection of exposure to sulfur mustard: Improvements on an assay for liquid chromatography-tandem mass spectrometry analysis of albumin/sulfur mustard adducts
article 2004    
Author: Noort, D. · Fidder, A. · Hulst, A.G. · Woolfitt, A.R. · Ash, D. · Barr, J.R.
Keywords: Toxicology · Tripeptide · Alkylation · Autoanalysis · Blood analysis · Chemical analysis · Chemical warfare · Controlled study · Digestion · Human · Human tissue · Liquid chromatography · Mass spectrometry · Protein isolation · Serum · Standard · Albumins · Alkylation · Chemical warfare agents · Chromatography, Affinity · Environmental exposure · Humans · Reference values · Retrospective studies · Mass spectrometry · Electrospray ionization · Mustard gas, 505-60-2 · Pronase, 9036-06-0 · Albumins
[PDF] [Abstract]

17 Klinische betekenis van extra vitaminen uit supplementen en verrijkte voedingsmiddelen [Clinical importance of extra vitamins from supplements and enriched foodstuffs]
article 1999    
Author: Hermus, R.J.J. · Severs, A.H.
Keywords: Nutrition · Copper · Retinol · Diabetes mellitus · Diet supplementation · Dose calculation · Elderly care · High risk patient · Human cell · Human tissue · Review · Vitamin intake · Adolescent · Adult · Aged · Avitaminosis · Child · Child, Preschool · Copper · Dietary Supplements · Female · Humans · Male · Middle Aged · Netherlands · Nutrition Policy · Nutritional Requirements · Pregnancy · Selenium · Vitamin A · Vitamin D · Zinc
[Abstract]

18 Quantification of perifosine, an alkylphosphocholine anti-tumour agent, in plasma by pneumatically assisted electrospray tandem mass spectrometry coupled with high-performance liquid chromatography
article 1999    
Author: Knebel, N.G. · Grieb, S. · Winkler, M. · Locher, M. · Vlis, E. van der · Verheij, E.R.
Keywords: Nutrition · Alkylphosphocholine · Perifosine · Antineoplastic agent · Miltefosine · Perifosine · Unclassified drug · Accuracy · Automation · Calibration · Controlled study · Drug blood level · Drug determination · High performance liquid chromatography · Human · Human experiment · Human tissue · Mass spectrometry · Oral drug administration · Priority journal · Solid phase extraction · Technique · Calibration · Chromatography, High Pressure Liquid · Humans · Mass Spectrometry · Phosphorylcholine · Quality Control · Spectrometry, Fluorescence · Spectrophotometry, Ultraviolet
[Abstract]

19 Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: A possible mechanism through which age is a risk factor for osteoarthritis
article 2002    
Author: Verzijl, N. · Groot, J. de · Zaken, C.B. · Braun-Benjamin, O. · Maroudas, A. · Bank, R.A. · Mizrahi, J. · Schalkwijk, C.G. · Thorpe, S.R. · Baynes, J.W. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · TeKoppele, J.M.
Keywords: Health Biology · Biomedical Research · 6 n carboxymethyllysine · Advanced glycation end product · Arginine · Collagen · Collagenase · Hydroxylysine · Pentosidine · Adult · Aging · Articular cartilage · Controlled study · Human · Human tissue · Hydration · Joint stiffness · Osmotic stress · Osteoarthritis · Priority journal · Protein cross linking · Protein glycosylation · Adult · Aging · Arginine · Cartilage, Articular · Collagen · Cross-Linking Reagents · Glycosylation End Products, Advanced · Humans · Lysine · Osteoarthritis · Pyruvaldehyde · Regression Analysis · Ribose · Stress, Mechanical · Tetroses
[Abstract]

20 Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: The use of pentosidine levels as a quantitative measure of protein turnover
article 2001    
Author: Verzijl, N. · Groot, J. de · Bank, R.A. · Bayliss, M.T. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · Maroudas, A. · TeKoppele, J.M.
Keywords: Health Biology · Biomedical Research · Articular cartilage · Osteoarthritis · Pentosidine · Turnover · Aspartic acid · Collagen · Hyaluronic acid · Protein · Binding site · Controlled study · Glycation · Half life time · Human tissue · Protein domain · Protein metabolism · School child · Adolescent · Adult · Aged · Aged, 80 and over · Aggrecans · Aging · Arginine · Cartilage, Articular · Chemical Fractionation · Child · Extracellular Matrix Proteins · Glycosylation End Products, Advanced · Humans · Lectins, C-Type · Lysine · Middle Aged · Osteoarthritis · Proteochondroitin Sulfates · Proteoglycans
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 129 found. Next | Sort by date