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1 Assessment of protein allergenicity studies in brown Norway rats
article 2002    
Author: Knippels, L.M.J. · Penninks, A.H.
Keywords: Toxicology · Allergens · Animals · Digestive System · Disease Models, Animal · Hypersensitivity · Immunoglobulin E · Male · Plants, Genetically Modified · Proteins · Rats · Animalia · Rattus norvegicus
[Abstract]

2 Effect of heat-induced aggregation on the IgE binding of patatin (Sol t 1) is dominated by other potato proteins
article 2002    
Author: Koppelman, S.J. · Koningsveld, G.A. van · Knulst, A.C. · Gruppen, H. · Pigmans, I.G.A.J. · Jongh, H.H.J. de
Keywords: Nutrition · Adult · Allergens · Calorimetry, Differential Scanning · Carboxylic Ester Hydrolases · Circular Dichroism · Food Hypersensitivity · Heat · Humans · Immunoglobulin E · Plant Proteins · Protein Denaturation · Protein Folding · Solanum tuberosum · Spectrometry, Fluorescence · Tryptophan
[Abstract]

3 Quantification of major peanut allergens Ara h 1 and Ara h 2 in the peanut varieties Runner, Spanish, Virginia, and Valencia, bred in different parts of the world
article 2001    
Author: Koppelman, S.J. · Vlooswijk, R.A.A. · Knippels, L.M.J. · Hessing, M. · Knol, E.F. · Reijsen, F.C. van · Bruijnzeel-Koomen, C.A.F.M.
Keywords: Arachis hypogaea · Food · IgE · Peanut · SDS-PAGE · food allergen · immunoglobulin E · protein · article · binding affinity · controlled study · enzyme linked immunosorbent assay · food allergy · human · nonhuman · peanut · polyacrylamide gel electrophoresis · priority journal · Adult · Allergens · Arachis hypogaea · Electrophoresis, Gel, Two-Dimensional · Enzyme-Linked Immunosorbent Assay · Food Hypersensitivity · Glycoproteins · Humans · Immunoglobulin E · Plant Proteins
[Abstract]

4 Development of atopic dermatitis in mice transgenic for human apolipoprotein C1
article 2008    
Author: Nagelkerken, L. · Verzaal, P. · Lagerweij, T. · Persoon-Deen, C. · Berbee, J.F.P. · Prens, E.P. · Havekes, L.M. · Oranje, A.P.
Keywords: Biology · Physiological Sciences · apolipoprotein C1 · corticosteroid · immunoglobulin E · animal tissue · article · atopic dermatitis · controlled study · histopathology · inflammatory cell · lichenoid eruption · lipid metabolism · mouse · nonhuman · priority journal · protein expression · Administration, Topical · Adrenal Cortex Hormones · Animals · Apolipoprotein C-I · Dermatitis, Atopic · Eosinophils · Epidermis · Female · Humans · Immunoglobulin E · Liver · Male · Mast Cells · Mice · Mice, Transgenic · Neutrophils · Pruritus
[Abstract]

5 Comparison of different immunochemical methods for the detection and quantification of hazelnut proteins in food products
article 1999    
Author: Koppelman, S. · Knulst, A.C. · Koers, W.J. · Penninks, A.H. · Peppelman, H. · Vlooswijk, R. · Pigmans, I. · Duijn, G. van · Hessing, M.
Keywords: Allergen · Detection · ELISA · Hazelnut · IgE · Immunoblotting · Food allergen · Immunoglobulin e · Rabbit antiserum · Vegetable protein · Controlled study · Enzyme linked immunosorbent assay · Food allergy · Food analysis · Food control · Food industry · Immunoblotting · Nonhuman · Polyacrylamide gel electrophoresis · Priority journal · Protein determination · Allergens · Animals · Cross Reactions · Enzyme-Linked Immunosorbent Assay · Food Analysis · Food Hypersensitivity · Humans · Immunoblotting · Immunochemistry · Immunoglobulin E · Molecular Weight · Nuts · Plant Proteins · Rabbits · Corylus · Oryctolagus cuniculus
[Abstract]

6 Coadministration of antigen and particles optimally stimulates the immune response in an intranasal administration model in mice
article 2001    
Author: Zijverden, M. van · Haar, C. de · Beelen, A. van · Loveren, H. van · Penninks, A. · Pieters, R.
Keywords: Nutrition · Administration, Intranasal · Animals · Antibody-Producing Cells · Carbon · Cell Count · Disease Models, Animal · Drug Administration Schedule · Enzyme-Linked Immunosorbent Assay · Female · Hypersensitivity · Immunoglobulin E · Immunoglobulin G · Lung · Lymph Nodes · Mice · Mice, Inbred BALB C · Ovalbumin · Particle Size · Time Factors · Animalia
[Abstract]

7 The relevance of a digestibility evaluation in the allergenicity risk assessment of novel proteins. Opinion of a joint initiative of COST action ImpARAS and COST action INFOGEST
article 2019    
Author: Verhoeckx, K. · Bogh, K.L. · Dupont, D. · Egger, L. · Gadermaier, G. · Larre, C. · Mackie, A. · Menard, O. · Adel-Patient, K. · Picariello, G. · Portmann, R. · Smit, J. · Turner, P. · Untersmayr, E. · Epstein, M.M.
Keywords: Allergenicity risk assessment · Food allergy · Food digestion · In vitro protein digestibility tests · Novel proteins · Immunoglobulin E antibody · Intestine enzyme · Protein · Allergenicity · Allergic reaction · Biological activity · Brush border · Digestion · Human · Immune response · Immunogenicity · In vitro study · Risk assessment · Sensitization · Workshop
[PDF] [Abstract]

8 Patients with anaphylaxis to pea can have peanut allergy caused by cross-reactive lgE to vicilin (Ara h 1)
article 2003    
Author: Wensing, M. · Knulst, A.C. · Piersma, S. · O'Kane, F. · Knol, E.F. · Koppelman, S.J.
Keywords: Nutrition Health · Food technology · Ara h 1 · Cross-reactivity · Pea · Peanut · Vicilin · allergen · immunoglobulin E · vicilin · adult · anaphylaxis · angioneurotic edema · antigen binding · article · case report · controlled study · cross reaction · dyspnea · enzyme linked immunosorbent assay · female · human · immunoblotting · male · pea · peanut · peanut allergy · prick test · priority journal · skin test · symptomatology · urticaria · Allergens · Anaphylaxis · Arachis hypogaea · Cross Reactions · Food Hypersensitivity · Humans · Immunoglobulin E · Peanut Hypersensitivity · Peas · Plant Proteins
[Abstract]

9 Brown Norway rat ovalbumin-specific immunoglobulin E antibodies increase the human basophil expression of CD63 marker
article 2003    
Author: Bellou, A. · Saint-Laudy, J. · Knippels, L. · Montémont, C. · Vauthier, E. · Gerard, P. · Pellegrom, H. · Koerkamp, E.K. · Lesesve, J.F. · Guéant, J.L. · Lambert, H. · Mallié, J.P.
Keywords: Toxicology Biology · Toxicology and Applied Pharmacology · CD63 antigen · immunoglobulin E · ovalbumin · adolescent · allergy test · anaphylactic shock · animal model · antibody response · antibody specificity · antigen expression · article · basophil · cell activation · enzyme linked immunosorbent assay · histamine release · human · human cell · immunization · nonhuman · passive skin anaphylaxis · priority journal · rat · rat strain · sensitization · serum · Th2 cell · Anaphylaxis · Animals · Antigens, CD · Basophils · Enzyme-Linked Immunosorbent Assay · Histamine Release · Humans · Immunization · Immunoglobulin E · Ovalbumin · Passive Cutaneous Anaphylaxis · Platelet Membrane Glycoproteins · Rats · Rats, Inbred BN
[Abstract]

10 Respiratory allergy and pulmonary irritation to trimellitic anhydride in Brown Norway rats
article 2003    
Author: Arts, J.H.E. · Bloksma, N. · Leusink-Muis, T. · Kuper, C.F.
Keywords: Biology Nutrition · Toxicology and Applied Pharmacology · Airway irritation · Brown Norway rats · Nonspecific airway hyperresponsiveness · Respiratory allergy · Trimellitic anhydride · acetylglucosaminidase · immunoglobulin E · irritant agent · lactate dehydrogenase · methacholine · protein · trimellitic anhydride · animal experiment · animal tissue · article · female · histopathology · immunoglobulin blood level · leukocyte · lung injury · lung lavage · nonhuman · occupational asthma · rat · respiratory tract allergy · sensitization · Allergens · Animals · Body Weight · Bronchoalveolar Lavage Fluid · Female · Immunization · Immunoglobulin E · Lung · Organ Size · Phthalic Anhydrides · Rats · Rats, Inbred BN · Respiration · Respiratory Function Tests · Rattus norvegicus
[Abstract]

11 Assessment of three human FcεRI-transfected RBL cell-lines for identifying IgE induced degranulation utilizing peanut-allergic patient sera and peanut protein extract
article 2008    
Author: Ladics, G.S. · Bilsen, J.H.M. van · Brouwer, H.M.H. · Vogel, L. · Vieths, S. · Knippels, L.M.J.
Keywords: Biological activity · Human FcεRI · Humanized rat basophilic leukemia cells · Mediator release · Peanut-allergic subjects · Protein cross-reactivity · beta n acetylhexosaminidase · Fc receptor · Food allergen · Allergen · Immunoglobulin E receptor · Food safety · Peanut · Tumor cell line · Arachis hypogaea · Rattus · Allergens · Animals · Arachis hypogaea · beta-N-Acetylhexosaminidases · Cell Degranulation · Cell Line, Tumor · Dose-Response Relationship, Immunologic · Humans · Immunoglobulin E · Mast Cells · Peanut Hypersensitivity · Plant Extracts · Rats · Receptors, IgE · Transfection
[Abstract]

12 Determination of pepsin-susceptible and pepsin-resistant epitopes in native and heat-treated peanut allergen Ara h 1
article 2008    
Author: Boxtel, E.L. van · Koppelman, S.J. · Broek, L.A.M. van den · Gruppen, H.
Keywords: Agriculture · Ara h 1 · Epitopes · Food allergy · IgE binding · Mass spectrometry · allergen · Ara h 1 protein, Arachis hypogaea · chymotrypsin · epitope · glycoprotein · immunoglobulin E · pepsin A · peptide fragment · vegetable protein · amino acid sequence · article · chemistry · heat · hydrolysis · immunology · metabolism · molecular genetics · molecular weight · Allergens · Amino Acid Sequence · Chymotrypsin · Epitopes · Glycoproteins · Heat · Hydrolysis · Immunoglobulin E · Molecular Sequence Data · Molecular Weight · Pepsin A · Peptide Fragments · Plant Proteins · Ara · Arachis hypogaea
[Abstract]

13 Humoral and cellular immune responses in different rat strains on oral exposure to ovalbumin
article 1999    
Author: Knippels, L.M.J. · Penninks, A.H. · Meeteren, M. van · Houben, G.F.
Keywords: Nutrition · Brown Norway · DTH · Food allergy · Hooded Lister · IgE · IgG · Oral · Ovalbumin · PVG · Rat · Wistar · Immunoglobulin e antibody · Immunoglobulin g antibody · Ovalbumin · Allergic reaction · Animal experiment · Animal model · Cellular immunity · Controlled study · Delayed hypersensitivity · Enzyme linked immunosorbent assay · Feeding · Food allergy · Humoral immunity · Immune response · Intragastric drug administration · Male · Nonhuman · Rat · Administration, Oral · Animals · Antibody Formation · Drug Hypersensitivity · Hypersensitivity, Delayed · Immunity, Cellular · Immunoglobulin E · Immunoglobulin G · Male · Ovalbumin · Rats · Rats, Inbred BN · Rats, Wistar · Species Specificity · Animalia · Rattus norvegicus
[Abstract]

14 Oral sensitization to food proteins: A Brown Norway rat model
article 1998    
Author: Knippels, L.M.J. · Penninks, A.H. · Spanhaak, S. · Houben, G.F.
Keywords: Nutrition · Brown Norway · DTH · Food allergy · IgE · IgG · Oral · Ovalbumin · Rat · Immunoglobulin e · Immunoglobulin g · Ovalbumin · Allergenicity · Allergy · Animal model · Article · Controlled study · Delayed hypersensitivity · Food allergy · Food intake · Nonhuman · Passive skin anaphylaxis · Priority journal · Protein analysis · Rat · Sensitization · Administration, Oral · Animals · Disease Models, Animal · Enzyme-Linked Immunosorbent Assay · Food Hypersensitivity · Hypersensitivity, Delayed · Immunoglobulin E · Immunoglobulin G · Male · Ovalbumin · Passive Cutaneous Anaphylaxis · Rats · Rats, Inbred BN
[Abstract]

15 Airway morphology and function of rats following dermal sensitization and respiratory challenge with low molecular weight chemicals
article 1998    
Author: Arts, J.H.E. · Kuper, C.F. · Spoor, S.M. · Bloksma, N.
Keywords: Nutrition · 1 chloro 2,4 dinitrobenzene · Immunoglobulin e · Salicylic acid methyl ester · Trimellitic anhydride · Airway · Animal experiment · Animal model · Animal tissue · Asthma · Breathing rate · Controlled study · Histopathology · Immunoglobulin blood level · Larynx · Lung function test · Morphology · Nonhuman · Occupational asthma · Provocation test · Rat · Sensitization · Allergens · Animals · Body Weight · Bronchi · Dermatitis, Allergic Contact · Dinitrochlorobenzene · Female · Immunoglobulin E · Organ Size · Phthalic Anhydrides · Rats · Rats, Inbred BN · Rats, Wistar · Respiratory Function Tests · Respiratory Hypersensitivity · Salicylates
[Abstract]

16 Children with peanut allergy recognize predominantly Ara h2 and Ara h6, which remains stable over time
article 2007    
Author: Flinterman, A.E. · Hoffen, E. van · Hartog Jager, C.F. den · Koppelman, S. · Pasmans, S.G. · Hoekstra, M.O. · Bruijnzeel-Koomen, C.A. · Knulst, A.C. · Knol, E.F.
Keywords: Nutrition · Food technology · Ara h2 and Ara h6 · Children · IgE reactivity · Peanut allergy · Stable individual recognition · immunoglobulin E · adolescent · antigen recognition · article · child · clinical article · controlled study · female · human · immunoblotting · immunoreactivity · male · peanut allergy · prick test · priority journal · provocation test · skin test · Adolescent · Adult · Allergens · Antibody Specificity · Child · Child, Preschool · Double-Blind Method · Female · Glycoproteins · Humans · Immunoblotting · Immunoglobulin E · Male · Peanut Hypersensitivity · Plant Proteins · Skin Tests · Time Factors
[Abstract]

17 Assessment of the allergic potential of food protein extracts and proteins on oral application using the Brown Norway rat model
article 2003    
Author: Knippels, L.M.J. · Penninks, A.H.
Keywords: Toxicology · Toxicology and Applied Pharmacology · Allergic potential · Brown Norway rats · Challenge effects · Egg-white proteins · Food allergy · Food proteins · IgE · Milk proteins · Oral sensitization · Ovalbumin · Passive cutaneous anaphylaxis · adjuvant · egg white · food allergen · immunoglobulin E · immunoglobulin G · ovalbumin · allergenicity · animal experiment · animal model · antibody response · antigen specificity · breathing rate · controlled study · feeding · food allergy · immune response · intestine mucosa permeability · male · milk allergy · nonhuman · peanut allergy · priority journal · protein intake · protein purification · provocation test · rat · rat strain · review · risk assessment · sensitization · symptomatology · systolic blood pressure · Administration, Oral · Allergens · Animals · Disease Models, Animal · Egg Proteins · Food Hypersensitivity · Humans · Immunoglobulin E · Immunoglobulin G · Male · Milk Proteins · Rats · Animalia · Arachis hypogaea · Rattus norvegicus
[Abstract]

18 Peanut allergen Ara h 3: Isolation from peanuts and biochemical characterization
article 2003    
Author: Koppelman, S.J. · Knol, E.F. · Vlooswijk, R.A.A. · Wensing, M. · Knulst, A.C. · Hefle, S.L. · Gruppen, H. · Piersma, S.
Keywords: Nutrition Health · Food technology · Allergens · IgE-binding · Peanut · Purification · allergen · Ara h 3 antigen · complementary DNA · glycinin · immunoglobulin E · peanut antigen · protein subunit · unclassified drug · allergenicity · amino acid sequence · amino terminal sequence · antigen binding · article · biochemistry · enzyme linked immunosorbent assay · gel permeation chromatography · nonhuman · peanut · peanut allergy · priority journal · protein analysis · protein folding · protein isolation · protein processing · protein purification · protein structure · protein unfolding · Western blotting · Allergens · Amino Acid Sequence · Arachis hypogaea · Calorimetry, Differential Scanning · Chromatography, Ion Exchange · Electrophoresis, Polyacrylamide Gel · Enzyme-Linked Immunosorbent Assay · Humans · Immunoblotting · Immunoglobulin E · Peanut Hypersensitivity
[Abstract]

19 CTLA-4 signaling regulates the intensity of hypersensitivity responses to food antigens, but is not decisive in the induction of sensitization
article 2005    
Author: Wijk, F. van · Hoeks, S. · Nierkens, S. · Koppelman, S.J. · Kooten, P. van · Boon, L. · Knippels, L.M.J. · Pieters, R.
Keywords: Nutrition toxicology · Food technology · cholera toxin · cytotoxic T lymphocyte antigen 4 · cytotoxic T lymphocyte antigen 4 monoclonal antibody · food allergen · food antigen · immunoglobulin E · monoclonal antibody · unclassified drug · animal cell · animal experiment · animal model · article · controlled study · cytokine production · female · hypersensitivity · mast cell degranulation · mouse · nonhuman · peanut allergy · priority journal · protein intake · regulatory mechanism · sensitization · signal transduction · Th2 cell · Adjuvants, Immunologic · Allergens · Animals · Antigens, CD · Antigens, Differentiation · Cytokines · Disease Models, Animal · Female · Immunoglobulin E · Mast Cells · Mice · Peanut Hypersensitivity · Signal Transduction · Th2 Cells
[Abstract]

20 Molecular characterization of trimellitic anhydride-induced respiratory allergy in Brown Norway rats
article 2008    
Author: Kuper, C.F. · Heijne, W.H. · Dansen, M. · Verhoeckx, K.C. · Boorsma, A. · Radonjic, M. · Bruijntjes, J. · Stierum, R. · Muijser, H. · Arts, J.H.
Keywords: Biology · Toxicology and Applied Pharmacology · Allergen · Immunoglobulin E · Phthalic anhydride · Toll like receptor · Trimellitic anhydride · Analysis of variance · Animal · Article · Blood · Brown Norway rat · Cluster analysis · DNA microarray · Drug effect · Female · Gene expression profiling · Genetics · Immunohistochemistry · Lung · Lung lavage · Metabolism · Nonparametric test · Pathology · Principal component analysis · Proteomics · Rat · Respiratory tract allergy · Signal transduction · Allergens · Analysis of Variance · Animals · Bronchoalveolar Lavage · Cluster Analysis · Female · Gene Expression Profiling · Immunoglobulin E · Immunohistochemistry · Lung · Oligonucleotide Array Sequence Analysis · Phthalic Anhydrides · Principal Component Analysis · Proteomics · Rats · Rats, Inbred BN · Respiratory Hypersensitivity · Signal Transduction · Statistics, Nonparametric · Toll-Like Receptors
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 57 found. Next | Sort by date