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Showing 1 to 16 of 16 found. | Sort by date

1 Quantitative risk reduction through peanut immunotherapy: Safety benefits of an increased threshold in Europe
article 2018    
Author: Remington, B.C. · Krone, T. · Koppelman, S.J.
Keywords: Nutrition · Efficacy · Immunotherapy · Peanut allergy · Risk reduction · Risk/Benefit Analysis
[PDF] [Abstract]

2 Approach toward a generic treatment of gram-negative infections: Synthesis of haptens for catalytic antibody mediated cleavage of the interglycosidic bond in lipid A
article 1999    
Author: Berg, R.J.B.H.N. van den · Noort, D. · Milder-Enacache, E.S. · Marel, G.A. van der · Boom, J.H. van · Benschop, H.P.
Keywords: Biology · Azasugars · Catalytic antibodies · Endotoxin · Glycosidases · Immunotherapy · Treatment · Infectious diseases · Antibodies · Immunology · Glycosides · Catalytic converters
[Abstract]

3 A network-based approach for identifying suitable biomarkers for oral immunotherapy of food allergy
article 2019    
Author: Bilsen, J.H.M. van · Verschuren, L. · Wagenaar, L. · Vonk, M.M. · Esch, B.C.A.M. van · Knippels, L.M.J. · Garssen, J. · Smit, J.J. · Pieters, R.H.H. · Broek, T.J. van den
Keywords: Bayesian network analyses · Bioinformatics · Experimental food allergy · Oral immunotherapy · Topological data analyses · Food and Nutrition · Healthy Living
[PDF] [Abstract]

4 Antigen-specific therapies in multiple sclerosis
article 1998    
Author: Noort, J.M. van
Keywords: Health · Antigen-specific theraphy · Autoimmunity · Multiple sclerosis · Adult · Animals · Antigens · Autoantigens · Encephalomyelitis, Autoimmune, Experimental · Humans · Immune Tolerance · Immunotherapy · Lymphocyte Activation · Major Histocompatibility Complex · Models, Biological · Multiple Sclerosis · Myelin Proteins · T-Lymphocytes
[Abstract]

5 CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis
article 1996    
Author: Gerritse, K. · Laman, J.D. · Noelle, R.J. · Aruffo, A. · Ledbetter, J.A. · Boersma, W.J.A. · Claassen, E.
Keywords: Health · Animals · Antibodies, Monoclonal · Antigens, CD40 · B-Lymphocytes · CD4-Positive T-Lymphocytes · CD40 Ligand · Encephalomyelitis, Autoimmune, Experimental · Female · Humans · Immunohistochemistry · Immunotherapy · Membrane Glycoproteins · Mice · Mice, Inbred Strains · Monocytes · Multiple Sclerosis · T-Lymphocytes, Helper-Inducer
[PDF] [Abstract]

6 Therapy with antibodies against CD40L (CD154) and CD44-variant isoforms reduces experimental autoimmune encephalomyelitis induced by a proteolipid protein peptide
article 1998    
Author: Laman, J.D. · Maassen, C.B.M. · Schellekens, M.M. · Visser, L. · Kap, M. · Jong, E. de · Puijenbroek, M. van · Stipdonk, M.J.B. van · Meurs, M. van · Schwärzler, C. · Günthert, U.
Keywords: Health · Accessory molecules · Blood-brain barrier · CD44 variant isoforms · Central nervous system (CNS) costimulation · Immunohistochemistry · Immunotherapy · Multiple sclerosis · Animals · Antibodies, Monoclonal · Antigens, CD40 · Antigens, CD44 · CD40 Ligand · Encephalomyelitis, Autoimmune, Experimental · Female · Immunization · Immunohistochemistry · Isoantigens · Membrane Glycoproteins · Mice · Myelin Proteolipid Protein · Peptide Fragments
[Abstract]

7 Understanding food allergen thresholds requires careful analysis of the available clinical data
article 2015    
Author: Taylor, S.L. · Houben, G.F. · Baumert, J.L. · Crevel, R.R.W.R. · Allen, K.J. · Dubois, A.E.J. · Knulst, A.C. · Remington, B.C. · Kruizinga, A.G. · Blom, W.M. · Brooke-Taylor, S.
Keywords: Health · Allergenicity · Allergic reaction · Egg allergy · Food allergy · Food processing · Geographic origin · Hazelnut allergy · Human · Immunotherapy · Letter · Milk allergy · Patient selection · Peanut · Peanut allergy · Priority journal · Public health · Statistical model · Healthy for Life · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences

8 Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis
article 1999    
Author: Howard, L.M. · Miga, A.J. · Vanderlugt, C.L. · Dal Canto, M.C. · Laman, J.D. · Noelle, R.J. · Miller, S.D.
Keywords: Biology · Animals · Antibodies · CD4-Positive T-Lymphocytes · CD40 Ligand · Cell Differentiation · Cell Division · Central Nervous System · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Female · Hypersensitivity, Delayed · Immunotherapy · Inflammation · Interferon Type II · Interleukins · Membrane Glycoproteins · Mice · Mice, Inbred Strains · Multiple Sclerosis · Myelin Proteolipid Protein · Myelin Sheath · Peptide Fragments · Th1 Cells
[PDF] [Abstract]

9 Interferon-β therapy reduces CD4+ and CD8+ T-cell reactivity in multiple sclerosis
article 2007    
Author: Zafranskaya, M. · Oschmann, P. · Engel, R. · Weishaupt, A. · Noort, J.M. van · Jomaa, H. · Eberl, M.
Keywords: Health · Biomedical Research · Autoimmunity · CFSE (5- (and 6-) carboxyfluorescein diacetate succinimidyl ester) · Disease progression · Immunotherapy · Myelin antigens · T-cell responses · beta1a interferon · CD45RO antigen · cytokine · interferon beta serine · myelin oligodendrocyte glycoprotein · adult · article · CD4+ T lymphocyte · CD8+ T lymphocyte · cell proliferation · clinical article · controlled study · correlation analysis · drug response · ex vivo study · female · functional status · human · human cell · immunotherapy · in vitro study · male · memory cell · multiple sclerosis · phenotype · prevalence · priority journal · Adult · Antigens, CD45 · CD4-Positive T-Lymphocytes · CD8-Positive T-Lymphocytes · Cell Proliferation · Cells, Cultured · Cytokines · Disease Progression · Flow Cytometry · Humans · Immunologic Memory · Immunophenotyping · Immunosuppressive Agents · Interferon-beta · Lymphocyte Activation · Middle Aged · Multiple Sclerosis, Relapsing-Remitting · Myelin-Associated Glycoprotein · T-Lymphocyte Subsets
[Abstract]

10 The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi
article 2003    
Author: Joosten, V. · Lokman, C. · Hondel, C.A.M.J.J. van den · Punt, P.J.
Keywords: Biology · Biotechnology · cancer antibody · cell antibody · fungus antibody · hybrid protein · immunoglobulin · immunoglobulin F(ab) fragment · immunoglobulin Fc fragment · immunoglobulin heavy chain · immunoglobulin light chain · intrabody · recombinant antibody · single chain fragment variable antibody · unclassified drug · antibody combining site · antibody production · antigen binding · Aspergillus awamori · Candida boidinii · clinical trial · drug clearance · drug delivery system · Escherichia coli · eukaryote · gene expression system · Hansenula polymorpha · human · immunotherapy · Kluyveromyces · methylotrophic bacterium · mycology · nonhuman · Pichia · Pichia methanolica · Pichia pastoris · protein protein interaction · protein synthesis · review · Saccharomyces cerevisiae · Schizosaccharomyces pombe · Trichoderma reesei · Yarrowia lipolytica · Eukaryota · Fungi
[Abstract]

11 New monoclonal antibodies against the putative immunosuppressive site of retroviral p15E
article 1994    
Author: Lang, M.S. · Oostendorp, R.A.J. · Simons, P.J. · Boersma, W. · Knegt, P. · Ewijk, W. van
Keywords: Monoclonal antibody · Monoclonal antibody er is1 · Monoclonal antibody er is2 · Monoclonal antibody er is5 · Unclassified drug · Airus protein · Antibody production · Antigen antibody reaction · Antigen recognition · Cancer cell culture · Cancer immunotherapy · Head and neck cancer · Human · Human cell · Retrovirus · Squamous cell carcinoma · Virus infection · Amino Acid Sequence · Antibodies, Monoclonal · Binding Sites, Antibody · Blotting, Western · Carcinoma, Squamous Cell · Cell Line · Conserved Sequence · Enzyme-Linked Immunosorbent Assay · Epitopes · Head and Neck Neoplasms · Immunoblotting · Immunohistochemistry · Immunosuppression · Laryngeal Neoplasms · Lung Neoplasms · Lymphoma, Large-Cell · Molecular Sequence Data · Peptides · Rauscher Virus · Retroviridae · Retroviridae Proteins, Oncogenic · Tumor Cells, Cultured · Antibodies, Monoclonal · Binding Sites, Antibody · Epitopes
[Abstract]

12 Functions of CD40 and its ligand, gp39 (CD40L)
article 1996    
Author: Laman, J.D. · Claassen, E. · Noelle, R.J.
Keywords: Biology · Antibody · Autoimmunity · CD40 · CD40 Ligand · Cognate T and B cell interaction · Gp39 · Isotype switching · Lymphocyte activation · Signal transduction · Tolerance · Cd40 antigen · Autoimmunity · B lymphocyte activation · Cell proliferation · Drug receptor binding · gGene switching · Germinal center · Human · Human cell · Immunological tolerance · Immunotherapy · Ligand binding · Lymphocyte activation · Review · Signal transduction · T lymphocyte activation · Animals · Antigens, CD40 · Antigens, Differentiation, T-Lymphocyte · Apoptosis · Autoimmune Diseases · CD40 Ligand · Gene Expression Regulation · Humans · Ligands · Lymphocytes · Membrane Glycoproteins · Mice · Mice, Knockout · Signal Transduction · Structure-Activity Relationship · Tumor Necrosis Factor-alpha
[Abstract]

13 Recombinant adenoviral vectors have adjuvant activity and stimulate T cell responses against tumor cells
article 2000    
Author: Geutskens, S.B. · Eb, M.M. van der · Plomp, A.C. · Jonges, L.E. · Cramer, S.J. · Ensink, N.G. · Kuppen, P.J.K. · Hoeben, R.C.
Keywords: Cancer gene therapy · IL-2 · Recombinant adenovirus · complementary DNA · cytokine · recombinant interleukin 2 · tumor antigen · virus vector · Adenovirus · Animal cell · Animal experiment · Animal model · Antigen recognition · Antineoplastic activity · Cancer inhibition · Colorectal cancer · Controlled study · Delayed hypersensitivity · DNA transfer · Gene expression · Gene therapy · immune response · Immunotherapy · Liver metastasis · Lymphocyte activation · Nonhuman · Rat strain · T lymphocyte · Transgene · Tumor cell · Tumor regression · Virus plaque · Virus recombinant · Virus replication · Adenoviridae · Animals · Colorectal Neoplasms · Flow Cytometry · Gene Therapy · Genetic Vectors · Histocompatibility Antigens Class I · Histocompatibility Antigens Class II · Humans · Intercellular Adhesion Molecule-1 · Interleukin-2 · Liver Neoplasms, Experimental · Lymphocyte Activation · Rats · Rats, Inbred Strains · T-Lymphocytes · Tumor Cells, Cultured · Adenoviridae · Animalia · DNA viruses
[Abstract]

14 Activation of the innate immune system in atherosclerotic disease
article 2007    
Author: Oude Nijhuis, M.M. · Keulen, J.K. van · Pasterkamp, G. · Quax, P.H. · Kleijn, D.P.V. de
Keywords: Biomedical Research · Atherogenesis · Infection · Inflammation · Innate immunity · Toll-like receptors · antibiotic agent · azithromycin · e 5331 · e 5531 · e 5564 · eritoran · ligand · lipid A derivative · lipopolysaccharide antagonist · low density lipoprotein · malonaldehyde · oxidized low density lipoprotein · placebo · receptor blocking agent · toll like receptor · vaccine · antigen recognition · atherogenesis · atherosclerosis · clinical trial · disease course · drug megadose · drug targeting · genetic polymorphism · human · innate immunity · knockout mouse · low drug dose · nonhuman · priority journal · review · signal transduction · vaccination · Animals · Atherosclerosis · Communicable Diseases · Humans · Immunity, Natural · Immunotherapy · Inflammation · Ligands · Lipopolysaccharides · Lipoproteins · Peptidoglycan · Signal Transduction · Toll-Like Receptors · Vaccines
[Abstract]

15 Food allergy: What do we learn from animal models?
article 2004    
Author: Knippels, L.M.J. · Wijk, F. van · Penninks, A.H.
Keywords: Health · Toxicology and Applied Pharmacology · Allergenicity · Animal models · Food allergy · Therapy · Ara h 1 allergen · Ara h 2 allergen · Ara h 3 allergen · DNA vaccine · food allergen · fungal immunomodulatory protein · fungal protein · immunoglobulin E antibody · protein fip fve · recombinant antigen · recombinant cytokine · recombinant peanut allergen · unclassified drug · allergenicity · antigen specificity · article · bacterium · clinical research · desensitization · dog · dose response · drug activity · drug mechanism · drug research · drug screening · food allergy · genetic susceptibility · health hazard · hypothesis · immunological tolerance · immunopathogenesis · immunoprophylaxis · mouse strain · nonhuman · pathophysiology · prediction · priority journal · protein degradation · protein diet · protein intake · protein structure · publication · rat strain · review · screening test · sensitization · swine · Th1 cell · Th2 cell · Animals · Food Hypersensitivity · Humans · Immunotherapy · Interleukin-10 · Interleukin-4 · Models, Animal · T-Lymphocytes
[Abstract]

16 Initiating mechanisms of food allergy: Oral tolerance versus allergic sensitization
article 2007    
Author: Wijk, F. van · Knippels, L.
Keywords: Nutrition · Toxicology and Applied Pharmacology · Dendritic cells · Food allergy · Oral tolerance · Regulatory T cells · allergen · B7 antigen · CD28 antigen · CD40 antigen · CD40 ligand · CD86 antigen · cytotoxic T lymphocyte antigen 4 · food antigen · gamma interferon · immunoglobulin A antibody · immunoglobulin E · interleukin 10 · neutralizing antibody · ovalbumin · peanut antigen · probiotic agent · transforming growth factor beta · tumor necrosis factor alpha · adaptive immunity · allergenicity · antibody production · antigen presenting cell · article · B lymphocyte · body surface · bystander effect · CD4+ CD25+ T lymphocyte · cell activation · cell interaction · cell maturation · cell subpopulation · cellular immunity · commensal · dendritic cell · food allergy · gastrointestinal mucosa · human · immune response · immune system · immunological tolerance · immunotherapy · innate immunity · intestine lymphatic tissue · intestine wall · lamina propria · lymphocyte · lymphoid tissue · mesentery lymph node · microenvironment · nonhuman · peanut allergy · Peyer patch · priority journal · protein analysis · protein intake · protein localization · regulatory T lymphocyte · signal transduction · T lymphocyte · T lymphocyte activation · Th3 cell · Antigens, CD · Food Hypersensitivity · Glycoproteins · Humans · Immune Tolerance · Immunization · Intestinal Mucosa · Lymph Nodes · Peyer's Patches · Receptors, Antigen, T-Cell
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 16 of 16 found. | Sort by date