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1 Appetite ratings of foods are predictable with an in vitro advanced gastrointestinal model in combination with an in silico artificial neural network
article 2019    
Author: Bellmann, S. · Krishnan, S. · Graaf, A. de · Ligt, R.A. de · Pasman, W.J. · Minekus, M. · Havenaar, R.
Keywords: Artificial neural network · Gastric viscosity · In silico modeling · in vitro gastrointestinal model · Prediction of fullness · Prediction of hunger · Cost effectiveness · Neural networks · Viscosity · Appetite · Clinical study · Cost effective · Cost-intensive · Gastrointestinal model · In-silico models · Input datas · Intestinal digestion · Forecasting · Food and Nutrition · Healthy Living
[Abstract]

2 Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs
article 2018    
Author: Notenboom, S. · Weigand, K.M. · Proost, J.H. · Lipzig, M.M.H. van · Steeg, E. van de · Broek, P.H.H. van den · Greupink, R. · Russel, F.G.M. · Groothuis, G.M.M.
Keywords: Biology · Bile acid handling · Biokinetic model · BSEP · Cholestasis · Human · In silico · NTCP · Biomedical Innovation · Healthy Living · Life Triskelion BV · MSB - Microbiology and Systems Biology ADME - ADME/DMPK · ELSS - Earth, Life and Social Sciences TNO Bedrijven
[PDF] [Abstract]

3 Reevaluation of the Munro dataset to derive more specific TTC thresholds
article 2014    
Author: Leeman, W.R. · Krul, L. · Houben, G.F.
Keywords: Nutrition · Health limit value · In silico · Reevaluation · Risk assessment · Threshold · Threshold of toxicological concern · TTC · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

4 The ChemScreen project to design a pragmatic alternative approachto predict reproductive toxicity of chemicals
article 2015    
Author: Van der Burg, B. · Wedebye, E.B. · Dietrich, D.R. · Jaworska, J. · Mangelsdorf, I. · Paune, E. · Schwarz, M. · Piersma, A.H. · Kroese, E.D.
Keywords: Toxicology Nutrition · In vitro · In silico · Integrated testing · Read accross · Reproductive toxicity · Endocrine disruptiona · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

5 Quercetin increases the bioavailability of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rats
article 2008    
Author: Schutte, M.E. · Alink, G.M. · Freidig, A.P. · Spenkelink, B. · Vaessen, J.C.H. · Sandt, J.J.M. van de · Groten, J.P. · Rietjens, I.M.C.M.
Keywords: Biology · Biomedical Research · ABC transporters · Caco-2 monolayers · In silico modelling · PhIP · Quercetin · Rat · 2 amino 1 methyl 6 phenylimidazo[4,5 b]pyridine · quercetin · animal experiment · animal tissue · article · bioavailability · cell strain CACO 2 · computer model · controlled study · dietary intake · human · human cell · in vitro study · in vivo study · male · nonhuman · rat · Animals · Antioxidants · Area Under Curve · Biological Availability · Biological Transport, Active · Caco-2 Cells · Carcinogens · Humans · Imidazoles · Male · Models, Biological · Quercetin · Random Allocation · Rats · Rats, Wistar · Rattus
[Abstract]

6 An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers
article 2006    
Author: Schutte, M.E. · Freidig, A.P. · Sandt, J.J.M. van de · Alink, G.M. · Rietjens, I.M.C.M. · Groten, J.P.
Keywords: Biology · Biomedical Research · ABC transporter · Caco-2 · Flavonoid · Heterocyclic amine · In silico · 2 amino 1 methyl 6 phenylimidazo[4,5 b]pyridine · breast cancer resistance protein · chrysoeriol · elacridar · flavone · flavonoid · kaempferol · luteolin · morin · multidrug resistance protein · myricetin · naringenin · quercetin · robinetin · taxifolin · unclassified drug · verlukast · absorption · apical membrane · article · cell strain CACO 2 · computer model · controlled study · drug effect · human · human cell · Acridines · ATP-Binding Cassette Transporters · Biological Transport, Active · Caco-2 Cells · Carcinogens · Cell Membrane Permeability · Diffusion · Dose-Response Relationship, Drug · Flavanones · Flavonoids · Humans · Imidazoles · Intestinal Absorption · Intestinal Mucosa · Kinetics · Membrane Transport Proteins · Models, Biological · Multidrug Resistance-Associated Proteins · Neoplasm Proteins · P-Glycoprotein · Propionates · Quinolines · Reproducibility of Results · Tetrahydroisoquinolines
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 6 of 6 found. | Sort by date