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Showing 1 to 7 of 7 found. | Sort by date

1 Chemical protection against X-irradiation by an orally administered compound
article 1980    
Author: Vos, O.
Keywords: Biology · Cysteine · Mercaptamine · N (1 adamantylmethyl)thioglycolamidine · Unclassified drug · Abstract report · Animal experiment · Ld 50 · Mouse · Oral drug administration · Radiation protection · X ray
[Abstract]

2 Strategies to replace in vivo acute systemic toxicity testing: The report and recommendations of ECVAM workshop 50
article 2004    
Author: Gennari, A. · Berghe, C. van den · Casati, S. · Castell, J. · Clemedson, C. · Coecke, S. · Colombo, A. · Curren, R. · Dal Negro, G. · Goldberg, A. · Gosmore, C. · Hartung, T. · Langezaal, I. · Lessigiarska, I. · Maas, W. · Mangelsdorf, I. · Parchment, R. · Prieto, P. · Sintes, J.R. · Ryan, M. · Schmuck, G. · Stitzel, K. · Stokes, W. · Vericat, J.A. · Gribaldo, L.
Keywords: Toxicology Health · Physiological Sciences · acute toxicity · conference paper · cytotoxicity · environmental protection · European Union · in vivo study · LD 50 · priority journal · toxicity testing · Acute Toxicity Tests · Animal Testing Alternatives · Animals · Cell Death · Cosmetics · Europe · Guidelines · Lethal Dose 50 · Mouth Diseases · Registries · Reproducibility of Results · Toxicity Tests · United States

3 Studies on the risk assessment of Listeria monocytogenes
article 1998    
Author: Notermans, S. · Dufrenne, J. · Teunis, P. · Chackraborty, T.
Keywords: Nutrition · animal · article · cheese · classification · comparative study · culture medium · female · germfree animal · human · immunization · LD 50 · Listeria monocytogenes · listeriosis · meat · microbiology · milk · mouse · pathogenicity · risk assessment · sea food · serotyping · vegetable · virulence · Animals · Cheese · Culture Media · Female · Fish Products · Humans · Immunization · Lethal Dose 50 · Listeria Infections · Listeria monocytogenes · Meat Products · Mice · Milk · Risk Assessment · Serotyping · Specific Pathogen-Free Organisms · Vegetables · Virulence
[Abstract]

4 Development of a QSAR for worst case estimates of acute toxicity of chemically reactive compounds
article 2007    
Author: Freidig, A.P. · Dekkers, S. · Verwei, M. · Zvinavashe, E. · Bessems, J.G.M. · Sandt, J.J.M. van de
Keywords: Biology · Analytical research · Biomedical research · Acute rodent toxicity · In vitro-in vivo correlation · QSAR · chemical compound · acute toxicity · article · clinical research · hazard assessment · in vitro study · in vivo study · LD 50 · mouse · nonhuman · prediction · priority journal · quantitative structure activity relation · rat · reference database · validation study · Algorithms · Animals · Data Interpretation, Statistical · Endpoint Determination · European Union · Forecasting · Hazardous Substances · Humans · Legislation · Lethal Dose 50 · Quantitative Structure-Activity Relationship · Reproducibility of Results · Animalia · Rattus · Rodentia
[Abstract]

5 Lung damage in the rat after irradiation and treatment with cytotoxic drugs
article 1986    
Author: Varekamp, A.E. · Vries, A.J. de · Hagenbeek, A.
Keywords: cyclophosphamide · cytarabine · cytotoxic agent · animal experiment · animal model · drug cytotoxicity · drug efficacy · histology · interstitial pneumonia · intoxication · intraperitoneal drug administration · intravenous drug administration · irradiation · lung function · lung injury · methodology · nonhuman · radiation injury · respiratory system · breathing · drug effect · LD 50 · pathophysiology · radiation exposure · radiation response · rat strain · Animal · Cyclophosphamide · Cytarabine · Dose-Response Relationship, Drug · Dose-Response Relationship, Radiation · Female · Lethal Dose 50 · Lung · Rats · Rats, Inbred Strains · Respiration
[PDF] [Abstract]

6 Hazard assessment of nitrosamine and nitramine by-products of amine-based CCS: Alternative approaches
article 2015    
Author: Buist, H.E. · Devito, S. · Goldbohm, R.A. · Stierum, R.H. · Venhorst, J. · Kroese, E.D.
Keywords: Nutrition · Carbon capture and storage · Carcinogenicity · Cell transformation assay · Mutagenicity · Nitramines · Nitrosamines · Predictive in vitro models · Predictive in vivo models · QSARs · Transgenic animal test · Aniline derivative · Nitrobenzene derivative · Animal · Biological model · Carbon sequestration · Carcinogen testing · Cell transformation · Chemical structure · Chemically induced · Chemistry · LD50 · Mutagen testing · Neoplasm · Procedures · Quantitative structure activity relation · Risk assessment · Transgenic mouse · Aniline Compounds · Animals · Carbon Sequestration · Carcinogenicity Tests · Cell Transformation, Neoplastic · Lethal Dose 50 · Mice, Transgenic · Models, Biological · Molecular Structure · Mutagenicity Tests · Neoplasms · Nitrobenzenes · Quantitative Structure-Activity Relationship · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

7 A physiologically based pharmacokinetic (PB/PK) model for multiple exposure routes for soman in multiple species
article 2006    
Author: Sweeney, R.E. · Langenberg, J.P. · Maxwell, D.M.
Keywords: Toxicology · Acetylcholinesterase · Carboxylesterase · Enzyme · Soman · Adipose tissue · Allometry · Animal experiment · Animal tissue · Arterial blood · Blood flow velocity · BLood level · Body weight · Breathing rate · Computer language · Computer simulation · Controlled study · Exposure · Guinea pig · In vitro study · Kidney perfusion · LD 50 · Liver perfusion · Lung perfusion · Male · Marmoset · Metabolism · Nonhuman · Partition coefficient · Priority journal · Provocation test · Rat · Regression analysis · Sensitivity analysis · Stereoisomerism · Tidal volume · Tissue level · Toxicokinetics · Venous blood · Administration, Inhalation · Animals · Callithrix · Chemical Warfare Agents · Cholinesterase Inhibitors · Computer Simulation · Guinea Pigs · Injections, Intravenous · Injections, Subcutaneous · Male · Models, Biological · Rats · Rats, Wistar · Animalia · Cavia porcellus · Marmosets · Acetylcholinesterase, 9000-81-1 · Carboxylesterase, 59536-71-9, 83380-83-0, 9016-18-6, 9028-01-7 · Soman, 96-64-0 · Chemical warfare agents · Cholinesterase inhibitors
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 7 of 7 found. | Sort by date