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1 Stimulation of the in Vivo Production of Very Low Density Lipoproteins by Apolipoprotein E Is Independent of the Presence of the Low Density Lipoprotein Receptor
article 2001    
Author: Teusink, B. · Mensenkamp, A.R. · Boom, H. van der · Kuipers, F. · Dijk, K.W. van · Havekes, L.M.
Keywords: Animalia · Gillia · Animals · Apolipoproteins E · Lipoproteins, VLDL · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Receptors, LDL
[PDF] [Abstract]

2 Oxidized VLDL induces less triglyceride accumulation in J774 macrophages than native VLDL due to an impaired extracellular lipolysis
article 2000    
Author: Jong, M.C. · Hendriks, W.L. · Vark, L.C. van · Dahlmans, V.E.H. · Groener, J.E.M. · Havekes, L.M.
Keywords: Biology · Lipid accumulation · Lipolysis · Macrophages · Oxidized VLDL · Animals · Cell Line · Lipolysis · Lipoprotein Lipase · Lipoproteins, VLDL · Macrophages · Mice · Oxidation-Reduction · Triglycerides
[Abstract]

3 Use of transgenic mice in lipoprotein metabolism and atherosclerosis research
article 1997    
Author: Havekes, L.M. · Vlijmen, B.J.M. van · Jong, M.C. · Dijk, K.W. van · Hofker, M.H.
Keywords: Biology · Age Factors · Animals · Apolipoprotein E3 · Apolipoproteins C · Apolipoproteins E · Arteriosclerosis · Cholesterol · Female · Humans · Lipids · Lipoproteins · Lipoproteins, VLDL · Male · Mice · Mice, Transgenic · Sex Factors · Animalia · Mus musculus
[Abstract]

4 Role of apoCs in lipoprotein metabolism : Functional differences between ApoC1, ApoC2, and ApoC3
article 1999    
Author: Jong, M.C. · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · Apolipoproteins · Lipoprotein lipase · Lipoproteins, VLDL · Mice, transgenic · Animals · Apolipoprotein C-I · Apolipoprotein C-II · Apolipoprotein C-III · Apolipoproteins C · Humans · Lipoproteins · Mice · Mice, Transgenic · Mutation
[Abstract]

5 Lipolysis of very low density lipoproteins by heparan sulfate proteoglycan-bound lipoprotein lipase
article 1997    
Author: Man, F.H.A.F. de · Beer, F. de · Laarse, A. van der · Smelt, A.H.M. · Havekes, L.M.
Keywords: Animals · Binding, Competitive · Cattle · Fatty Acids · Heparan Sulfate Proteoglycans · Heparin Lyase · Humans · Iodine Radioisotopes · Kinetics · Lipolysis · Lipoprotein Lipase · Lipoproteins, VLDL · Protein Binding · Radioligand Assay · Triglycerides
[PDF] [Abstract]

6 Hyperlipidemia in APOE2 transgenic mice is ameliorated by a truncated apoE variant lacking the C-terminal domain
article 2003    
Author: Gerritsen, G. · Kypreos, K.E. · Zee, A. van der · Teusink, B. · Zannis, V.I. · Havekes, L.M. · Dijk, K.W. van
Keywords: Biology · Adenoviridae · Animals · Apolipoprotein E2 · Apolipoprotein E4 · Apolipoproteins E · Cholesterol · Humans · Hyperlipidemias · Lipids · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Protein Isoforms · Protein Structure, Tertiary · Triglycerides
[PDF] [Abstract]

7 Mice expressing only the mutant APOE3Leiden gene show impaired VLDL secretion
article 2001    
Author: Mensenkamp, A.R. · Teusink, B. · Baller, J.F.W. · Wolters, H. · Havinga, R. · Dijk, K.W. van · Havekes, L.M. · Kuipers, F.
Keywords: Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Fatty Liver · Lipid Metabolism · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Protein Isoforms · RNA, Messenger · Triglycerides
[Abstract]

8 Effect of apolipoprotein E variants on lipolysis of very low density lipoproteins by heparan sulphate proteoglycan-bound lipoprotein lipase
article 1998    
Author: Man, F.H.A.F. de · Beer, F. de · Laarse, A. van der · Smelt, A.H.M. · Leuven, J.A.G. · Havekes, L.M.
Keywords: Health · Atherosclerosis · Familial dysbetalipoproteinemia · Metabolism · Triglyceride · VLDL · Adult · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Female · Heparan Sulfate Proteoglycans · Heterozygote · Homozygote · Humans · Hyperlipoproteinemia Type III · Lipolysis · Lipoprotein Lipase · Lipoproteins, VLDL · Male · Middle Aged
[Abstract]

9 Binding and transfer of verocytotoxin by polymorphonuclear leukocytes in hemolytic uremic syndrome
article 2000    
Author: Loo, D.M.W.M. te · Monnens, L.A.H. · Velden, T.J.A.M. van der · Vermeer, M.A. · Preyers, F. · Demacker, P.N.M. · Heuvel, L.P.W.J. van den · Hinsbergh, V.W.M. van
Keywords: Biology · Adult · Bacterial Toxins · Child · Endothelium, Vascular · Escherichia coli · Fluorescein-5-isothiocyanate · Hemolytic-Uremic Syndrome · Humans · Iodine Radioisotopes · Kidney Glomerulus · Kinetics · Lipoproteins · Lipoproteins, HDL · Lipoproteins, LDL · Lipoproteins, VLDL · Microcirculation · Neutrophils · Receptors, Cell Surface · Shiga-Like Toxin I · Trihexosylceramides
[Abstract]

10 The Hyplip2 locus causes hypertriglyceridemia by decreased clearance of triglycerides
article 2007    
Author: Moen, C.J.A. · Tholens, A.P. · Voshol, P.J. · Haan, W. de · Havekes, L.M. · Gargalovic, P. · Lusis, A.J. · Dyk, K.W. van · Frants, R.R. · Hofker, M.H. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Congenic mice · Lipoprotein clearance · Lipoprotein lipase · Lipoproteins · Triglyceride hydrolysis · Animals · Chylomicrons · Female · Genetic Techniques · Hypertriglyceridemia · Lipase · Lipoprotein Lipase · Lipoproteins · Lipoproteins, VLDL · Mice · Mice, Congenic · Postprandial Period · Triglycerides
[PDF] [Abstract]

11 Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver
article 1999    
Author: Mensenkamp, A.R. · Jong, M.C. · Goor, H. van · Luyn, M.J.A. van · Bloks, V. · Havinga, R. · Voshol, P.J. · Hofker, M.H. · Dijk, K.W. van · Havekes, L.M. · Kuipers, F.
Keywords: Biology · Animals · Apolipoproteins E · Cells, Cultured · Cholesterol · Crosses, Genetic · Fatty Acids, Nonesterified · Glycerol · Homeostasis · Humans · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Knockout · Mice, Transgenic · Microscopy, Immunoelectron · Phytosterols · Sitosterols · Sterols · Triglycerides · Tritium
[PDF] [Abstract]

12 In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE
article 1999    
Author: Dijk, K.W. van · Vlijmen, B.J.M. van · Hof, H.B. van 't · Zee, A. van der · Santamarina-Fojo, S. · Berkel, T.J.C. van · Havekes, L.M. · Hofker, M.H.
Keywords: Health · Adenovirus-mediated gene transfer · Hepatic VLDL triglyceride production · Hypertriglyceridemia · LDL receptor-related protein · VLDL-triglyceride lipolysis · Adenovirus · Adenoviridae · Animals · Apolipoproteins E · Cholesterol · Female · Humans · Immunohistochemistry · Lipolysis · Lipoprotein Lipase · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Receptors, LDL · Transfection · Triglycerides
[PDF] [Abstract]

13 Lipoprotein secretion by isolated rat hepatocytes: Characterization of the lipid-carrying particles and modulation of their release
article 1980    
Author: Kempen, H.J.M.
Keywords: Biology · Lipid · Lipoprotein · Animal experiment · Density gradient centrifugation · In vitro study · Liver cell · Animal · Apolipoproteins · Cholesterol · Cholesterol Esters · Colchicine · Comparative Study · Cycloheximide · Lipoproteins, VLDL · Liver · Male · Phospholipids · Rats · Triglycerides
[PDF] [Abstract]

14 Vastatins inhibit cholesterol ester accumulation in human monocyte-derived macrophages
article 1991    
Author: Kempen, H.J.M. · Vermeer, M. · Wit, E.de · Havekes, L.M.
Keywords: Biology · Acetyl low density lipoproteins · Mevastatin · Modified low density lipoproteins · Cholesterol ester · Compactin · Mevinolin · Pravastatin · Human cell · Anticholesteremic Agents · Cholesterol Esters · Esterification · Human · In Vitro · Lipoproteins, LDL · Lipoproteins, VLDL · Lovastatin · Macrophages · Monocytes · Oleic Acids · Phospholipids · Simvastatin
[Abstract]

15 The binding of human lipoprotein lipase treated VLDL by the human hepatoma cell line HepG2
article 1991    
Author: Mulder, M. · Wit, E.de · Havekes, L.M.
Keywords: Biology · HepG2 cell line · LDLD receptor · Lipoprotein lipase · Remnant receptor · VLDL · VLDL remnant · Binding, Competitive · Carcinoma, Hepatocellular · Human · Lipoprotein Lipase · Lipoproteins, LDL · Lipoproteins, VLDL · Liver Neoplasms · Receptors, LDL · Triglycerides · Tumor Cells, Cultured · Bovinae
[Abstract]

16 Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice
article 2001    
Author: Jong, M.C. · Rensen, P.C.N. · Dahlmans, V.E.H. · Boom, H. van der · Berkel, T.J.C. van · Havekes, L.M.
Keywords: Animals · Apolipoprotein C-III · Apolipoproteins C · Apolipoproteins E · Chylomicrons · Crosses, Genetic · Female · Gene Deletion · Hydrolysis · Lipoprotein Lipase · Lipoproteins, VLDL · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Time Factors · Triglycerides
[PDF] [Abstract]

17 In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2(Arg-158 → Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice
article 1996    
Author: Vlijmen, B.J.M. van · Dijk, K.W. van · Hof, H.B. van 't · Gorp, P.J.J. van · Zee, A. van der · Boom, H. van der · Breuer, M.L. · Hofker, M.H. · Havekesf, L.M.
Keywords: Animals · Apolipoproteins E · Arginine · Cells, Cultured · Cysteine · Genes, Dominant · Heymann Nephritis Antigenic Complex · Hyperlipoproteinemias · Lipoproteins, LDL · Lipoproteins, VLDL · Membrane Glycoproteins · Mice · Mice, Knockout · Mice, Transgenic · Receptors, LDL · Adenoviridae · Animalia · Mus musculus
[PDF] [Abstract]

18 Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis
article 2000    
Author: Rensen, P.C.N. · Jong, M.C. · Vark, L.C. van · Boom, H. van der · Hendriks, W.L. · Berkel, T.J.C. van · Biessen, E.A.L. · Havekes, L.M.
Keywords: Animals · Apolipoproteins B · Apolipoproteins E · Biological Transport · Blood · Cells, Cultured · Cholesterol Esters · Emulsions · Endocytosis · Lipoproteins · Lipoproteins, LDL · Lipoproteins, VLDL · Liver · Lysosomes · Male · Mice · Mice, Inbred C57BL · Protein Processing, Post-Translational · Animalia
[PDF] [Abstract]

19 Cafestol increases serum cholesterol levels in apolipoprotein E*3- leiden transgenic mice by suppression of bile acid synthesis
article 2000    
Author: Post, S.M. · Roos, B.de · Vermeulen, M. · Afman, L. · Jong, M.C. · Dahlmans, V.E.H. · Havekes, L.M. · Stellaard, F. · Katan, M.B. · Princen, H.M.G.
Keywords: Biology · Animals · Apolipoprotein E3 · Apolipoproteins E · Bile Acids and Salts · Cholesterol · Diet · Diterpenes · Feces · Female · Lipid Metabolism · Lipoproteins · Lipoproteins, IDL · Lipoproteins, VLDL · Liver · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Receptors, LDL
[Abstract]

20 Apolipoprotein E2 (Lys146→Gln) causes hypertriglyceridemia due to an apolipoprotein E variant-specific inhibition of lipolysis of very low density lipoproteins-triglycerides
article 2000    
Author: Beer, F. de · Dijk, K.W. van · Jong, M.C. · Vark, L.C. van · Zee, A. van der · Hofker, M.H. · Fallaux, F.J. · Hoeben, R.C. · Smelt, A.H.M. · Havekes, L.M.
Keywords: Adenoviridae · Alleles · Animals · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Gene Expression · Gene Transfer Techniques · Humans · Hydrolysis · Hyperlipoproteinemia Type III · Hypertriglyceridemia · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · Point Mutation · RNA, Messenger · Triglycerides
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 45 found. Next | Sort by date