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Showing 1 to 13 of 13 found. | Sort by date

1 Perfluoroalkyl sulfonates cause alkyl chain length-dependent hepatic steatosis and hypolipidemia mainly by impairing lipoprotein production in APOE*3-leiden CETP mice
article 2011    
Author: Bijland, S. · Rensen, P.C.N. · Pieterman, E.J. · Maas, A.C.E. · Hoorn, J.W. van der · Erk, M.J. van · Havekes, L.M. · Dijk, K.W. van · Chang, S.C. · Ehresman, D.J. · Butenhoff, J.L. · Princen, H.M.G.
Keywords: Health · Cholesterol · Lipoprotein · Perfluorooctane sulfonate · PPARa · PXR · Triglyceride · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

2 Diagnostic markers based on a computational model of lipoprotein metabolism
article 2011    
Author: Schalkwijk, D.B. van · Ommen, B. van · Freidig, A.P. · Greef, J. van der · Graaf, A.A. de
Keywords: Biology · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

3 Moderate alcohol consumption alters both leucocyte gene expression profiles and circulating proteins related to immune response and lipid metabolism in men
article 2012    
Author: Joosten, M.M. · Erk, M.J. van · Pellis, L · Witkamp, R.F. · Hendriks, H.F.
Keywords: Health · Biomedical Innovation · Healthy Living · Life Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research PHS - Pharmacokinetics & Human Studies · EELS - Earth, Environmental and Life Sciences
[PDF]

4 Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity
article 2013    
Author: Coomans, C.P. · Berg, S.A.A. van den · Houben, T. · Klinken, J.B. van · Berg, R. van den · Pronk, A.C.M. · Havekes, L.M. · Romijn, J.A. · Dijk, K.W. van · Biermasz, N.R. · Meijer, J.H.
Keywords: Health · Constant light · Electrophysiology · Multiunit activity · SCN · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

5 Distribution of perfluorooctanesulfonate and perfluorooctanoate into human plasma lipoprotein fractions
article 2012    
Author: Butenhoff, J.L. · Pieterman, E. · Ehresman, D.J. · Gorman, G.S. · Olsen, G.W. · Chang, S.C. · Princen, H.M.
Keywords: Toxicology · Perfluorooctanoate · Perfluorooctanesulfonate · Cholesterol · Lipoprotein · Fractionation · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

6 Developing computational model-based diagnostics to analyse clinical chemistry data
article 2010    
Author: Schalkwijk, D.B. van · Bochove, K. van · Ommen, B. van · Freidig, A.P. · Someren, E.P. van · Greef, J. van der · Graaf, A.A. de
Keywords: Biology · Biomedical Research · Clinical chemistry · Clinical diagnostics · Computational modelling · Lipoprotein metabolism · Particle profiler · Probabilistic and deterministic modelling · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

7 Systems biology analysis unravels the complementary action of combined rosuvastatin and ezetimibe therapy
article 2012    
Author: Verschuren, L. · Radonjic, M. · Wielinga, P.Y. · Kelder, T. · Kooistra, T. · Ommen, B. van · Kleemann, R.
Keywords: Biology · adverse effect · coamplified · combination therapy · inflammation · mouse model · systems biology · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

8 Differential Effects of Drug Interventions and Dietary Lifestyle in Developing Type 2 Diabetes and Complications: A Systems Biology Analysis in LDLr-/- Mice
article 2013    
Author: Radonjic, M. · Wielinga, P.Y. · Wopereis, S. · Kelder, T. · Goelela, V.S. · Verschuren, L. · Toet, K. · Duyvenvoorde, W. van · Werff van der Vat, B. van der · Stroeve, J.H.M. · Cnubben, N. · Kooistra, T. · Ommen, B. van · Kleemann, R.
Keywords: Biology · Biomedical Innovation · Healthy Living · Life Life Triskelion BV · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research TARA - Toxicology and Risk Assessment · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

9 Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status
article 2012    
Author: Pellis, L. · Erk, M.J. van · Ommen, B. van · Bakker, G.C.M. · Hendriks, H.F.J. · Cnubben, N.H.P. · Kleemann, R. · Someren, E.P. van · Bobeldijk, I. · Rubingh, C.M. · Wopereis, S.
Keywords: Biology · Metabolic profiling · Plasma · Postprandial challenge · Proteomic profiling · Healthy for Life · Healthy Living · Life Triskelion · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research PHS - Pharmacokinetics & Human Studies RAPID - Risk Analysis for Products in Development · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

10 PET imaging of disease progression and treatment effects in the experimental autoimmune encephalomyelitis rat model
article 2014    
Author: Paula Faria, D. de · Vlaming, M.L.H. · Copray, S.C.V.M. · Tielen, F. · Anthonijsz, H.J.A. · Sijbesma, J.W.A. · Buchpiguel, C.A. · Dierckx, R.A.J.O. · Hoorn, J.W.A. van der · Vries, E.F.J. de
Keywords: Biology · Demyelination · Multiple sclerosis · Neuroinflammation · PET imaging · Dexamethasone acetate · MeDAS c 11 · Myelin oligodendrocyte glycoprotein · N sec butyl 1 (2 chlorophenyl) n methyl 3 isoquinolinecarboxamide c 11 · Radiopharmaceutical agent · Unclassified drug · Animal cell · Animal experiment · Animal model · Animal tissue · Brain region · Cell invasion · Controlled study · Demyelination · Disease course · Drug effect · Experimental autoimmune encephalomyelitis · Female · In vivo study · Microglia · Monocyte · Neuroimaging · Nonhuman · PET scanner · Positron emission tomography · Priority journal · Rat · Scoring system · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

11 Salsalate attenuates diet induced non-alcoholic steatohepatitis in mice by decreasing lipogenic and inflammatory processes
article 2015    
Author: Liang, W. · Verschuren, L. · Mulder, P. · Hoorn, J.W.A. van der · Verheij, J. · Dam, A.D. van · Boon, M.R. · Princen, H.M.G. · Havekes, L.M. · Kleemann, R. · Hoek, A.M. van den
Keywords: Biology · Alanine aminotransferase · Aspartate aminotransferase · Glucose · High density lipoprotein cholesterol · Insulin · Interleukin 6 · Low density lipoprotein cholesterol · Peroxisome proliferator activated receptor alpha · Salsalate · Triacylglycerol · Alanine aminotransferase blood level · Animal cell · Animal experiment · Animal model · Animal tissue · Aspartate aminotransferase blood level · Body weight · Controlled study · Down regulation · Drug efficacy · Drug response · Dyslipidemia · Energy metabolism · Fatty acid oxidation · Fatty liver · Gene expression · Glucose blood level · Glycemic control · Hepatitis · Insulin blood level · Insulin resistance · Lipid metabolism · Lipogenesis · Male · Mouse · Nonalcoholic fatty liver · Nonhuman · Treatment duration · Treatment outcome · Triacylglycerol blood level · Upregulation · Weight gain · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

12 A dietary mixture containing fish oil, resveratrol, lycopene, catechins, and vitamins E and C reduces atherosclerosis in transgenic mice
article 2011    
Author: Verschuren, L. · Wielinga, P.Y. · Duyvenvoorde, W. van · Tijani, S. · Toet, K. · Ommen, B. van · Kooistra, T. · Kleemann, R.
Keywords: Nutrition · alpha tocopherol · apolipoprotein E3 · ascorbic acid · biological marker · C reactive protein · catechin · cell adhesion molecule · cholesterol · cytokine · docosahexaenoic acid · endothelial leukocyte adhesion molecule 1 · epigallocatechin gallate · fibrinogen · fish oil · green tea extract · icosapentaenoic acid · intercellular adhesion molecule 1 · interleukin 1beta · lipid · lycopene · omega 3 700 · placebo · polyunsaturated fatty acid · resveratrol · serum amyloid A · triacylglycerol · unclassified drug · animal experiment · animal model · antiinflammatory dietary mixture · article · atherogenic diet · atherosclerosis · cholesterol blood level · controlled study · diet supplementation · dietary intake · drug efficacy · drug megadose · feeding · female · inflammation · long term care · male · mouse · nonhuman · powder · protein blood level · protein expression · risk factor · risk reduction · transgenic animal · treatment duration · treatment outcome · triacylglycerol blood level · vasculitis · omega 3 700 · Solgar Vitamin and Herb · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

13 Identification of prognostic and diagnostic biomarkers of glucose intolerance in ApoE3Leiden mice
article 2012    
Author: Wopereis, S. · Radonjic, M. · Rubingh, C. · Erk, M. van · Smilde, A. · Duyvenvoorde, W. van · Cnubben, N. · Kooistra, T. · Ommen, B. van · Kleemann, R.
Keywords: Biology · Diabetes mellitus Type 2 · Diabetes mellitus Type 2-prone transgenic ApoE3Leiden mice · Plasma lipidomics · White blood cell transcriptomics · acyl coA synthetase short chain family member 2 · adp ribosylation factor gtaase activating protein 1 · atp binding cassette subfamily b protein · biological marker · cytochrome c oxidase subunit vib polypeptide 2 · cytochrome P450 2B1 · fatty acid · fibroblast growth factor 16 · lipidome · seryl aminoacyl tRNA synthetase 2 · transcription elongation factor a like 8 protein · transcriptome · transferrin receptor · unclassified drug · animal cell · animal experiment · animal model · area under the curve · article · blood analysis · controlled study · disease course · gene expression · glucose intolerance · glucose tolerance test · leukocyte · lipid blood level · lipid diet · lipidomics · mouse · nonhuman · prediction · priority journal · prognosis · protein analysis · transcriptomics · Healthy for Life · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research PHS - Pharmacokinetics & Human Studies RAPID - Risk Analysis for Products in Development · EELS - Earth, Environmental and Life Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 13 of 13 found. | Sort by date