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Showing 1 to 18 of 18 found. | Sort by date

1 Simvastatin improves disturbed endothelial barrier function
article 2000    
Author: Nieuw Amerongen, G.P. van · Vermeer, M.A. · Negre-Aminou, P. · Lankelma, J. · Emeis, J.J. · Hinsbergh, V.W.M. van
Keywords: Animals · Aorta · Arteriosclerosis · Capillary Permeability · Cell Membrane Permeability · Cells, Cultured · Cholesterol · Cholesterol, LDL · Disease Models, Animal · Endothelium, Vascular · Humans · Hypercholesterolemia · Rabbits · Simvastatin
[Abstract]

2 In vitro intestinal lead uptake and transport in relation to speciation
article 2003    
Author: Oomen, A.G. · Tolls, J. · Sips, A.J.A.M. · Groten, J.P.
Keywords: Biology Health · Physiological Sciences · lead · pollution exposure · article · bioavailability · cell strain CACO 2 · controlled study · first pass effect · human · human cell · intestine absorption · lead poisoning · membrane permeability · metal metabolism · priority journal · risk assessment · soil pollution · tissue level · Administration, Oral · Biological Availability · Caco-2 Cells · Digestive System · Humans · Intestinal Mucosa · Ions · Lead · Soil Pollutants
[Abstract]

3 Effects of saponins and glycoalkaloids on the permeability and viability of mammalian intestinal cells and on the integrity of tissue preparations in vitro
article 1996    
Author: Gee, J.M. · Wortley, G.M. · Johnson, I.T. · Price, K.R. · Rutten, A.A.J.J.L. · Houben, G.F. · Penninks, A.H.
Keywords: Toxicology · Alkaloid · Chaconine · Lactate dehydrogenase · Saponin · Solanine · Tomatine · Unclassified drug · Animal cell · Cell culture · Cell membrane · Cell viability · Chemical interaction · Controlled study · Cytotoxicity · Human · Human cell · In vitro study · Intestine epithelium · Intestine mucosa · Jejunum · Membrane depolarization · Membrane permeability · Nonhuman · Rat · Gypsophila spp. · Lycopersicon esculentum · Solanum tuberosum
[Abstract]

4 Percutaneous penetration studies for risk assessment
article 2000    
Author: Sartorelli, P. · Andersen, H.R. · Angerer, J. · Corish, J. · Drexler, H. · Göen, T. · Griffin, P. · Hotchkiss, S.A.M. · Larese, F. · Montomoli, L. · Perkins, J. · Schmelz, M. · Sandt, J. van de · Williams, F.
Keywords: Nutrition · Cutaneous metabolism · Diffusion cell · Guidelines · In vitro · Microdialysis · Percutaneous penetration · Regulatory toxicology · Risk assessment · Alcohol derivative · Electrolyte · Hydrocarbon · Insecticide · Macrogol derivative · Penetration enhancing agent · Pesticide · Solvent · Steroid · Surfactant · Toxic substance · Volatile agent · Diffusion · Drug penetration · Human · Membrane permeability · Microdialysis · Nonhuman · Practice guideline · Priority journal · Review · Risk assessment · Skin absorption · Skin penetration · Standardization · Xenobiotic metabolism
[Abstract]

5 Direct cell-to-cell contact between Kupffer cells and hepatocytes augments endotoxin-induced hepatic injury
article 2001    
Author: Hoebe, K.H.N. · Witkamp, R.F. · Fink-Gremmels, J. · Miert, A.S.J.P.A.M. van · Monshouwer, M.
Keywords: Nutrition · Animals · Biotransformation · Blotting, Western · Cell Communication · Cell Membrane Permeability · Cell Survival · Cells, Cultured · Coculture Techniques · Endotoxins · Hepatitis, Toxic · Hepatocytes · Immunohistochemistry · Interleukin-6 · Kupffer Cells · Male · Nitric Oxide · Nitric Oxide Synthase · Nitric Oxide Synthase Type II · Reactive Oxygen Species · Swine · Tumor Necrosis Factor-alpha
[Abstract]

6 The effect of protein-protein and protein-membrane interactions on membrane fouling in ultrafiltration
article 2000    
Author: Huisman, I.H. · Prádanos, P. · Hernández, A.
Keywords: Nutrition · Fouling · Physicochemical interactions · Protein · Protein-membrane interactions · Ultrafiltration · Atomic force microscopy · Mechanical permeability · PH effects · Proteins · Ultrafiltration · Bovine serum albumin · Polymeric membranes · Bovine serum albumin · Electrolyte · Polymer · Polysulfone · Protein · Membrane · Membrane technology · Ultrafiltration · Artificial membrane · Atomic force microscopy · Membrane permeability · Membrane transport · Performance · PH · Priority journal · Protein analysis · Protein protein interaction · Protein transport · Ultrafiltration
[Abstract]

7 Activation of rhoa by thrombin in endothelial hyperpermeability: Role of rho kinase and protein tyrosine kinases
article 2000    
Author: Nieuw Amerongen, G.P. van · Delft, S.V. · Vermeer, M.A. · Collard, J.G. · Hinsbergh, V.W.M. van
Keywords: Amides · Calcium · Cell Membrane Permeability · Cells, Cultured · Cytoskeleton · Endothelium, Vascular · Enzyme Activation · Enzyme Inhibitors · Hemostatics · Humans · Intracellular Signaling Peptides and Proteins · Myosin Light Chains · Phosphorylation · Protein Binding · Protein-Serine-Threonine Kinases · Protein-Tyrosine Kinases · Proto-Oncogene Proteins c-akt · Pyridines · rhoA GTP-Binding Protein · Thrombin · Umbilical Veins
[Abstract]

8 Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients
article 2002    
Author: Kuenen, B.C. · Levi, M. · Meijers, J.C.M. · Kakkar, A.K. · Hinsbergh, V.W.M. van · Kostense, P.J. · Pinedo, H.M. · Hoekman, K.
Keywords: Angiogenesis Inhibitors · Blood Coagulation · Blood Platelets · Carcinoma, Renal Cell · Cell Division · Cell Membrane Permeability · Cell Movement · Drug Administration Schedule · Endothelium, Vascular · Fibrinolysis · Hemostasis · Indoles · Kidney Neoplasms · Melanoma · Neovascularization, Pathologic · Protein C · Proto-Oncogene Proteins · Pyrroles · Receptor Protein-Tyrosine Kinases · Receptors, Growth Factor · Receptors, Vascular Endothelial Growth Factor · Sarcoma · Thrombin · Vascular Endothelial Growth Factor Receptor-1
[Abstract]

9 Leakage evolution and atomic-scale changes in Pd-based membranes induced by long-term hydrogen permeation
article 2018    
Author: Peters, T.A. · Carvalho, P.A. · Wees, J.F. van · Overbeek, J.P. · Sagvolden, E. · Berkel, F.P.F. van · Løvvik, O.M. · Bredesen, R.
Keywords: Energy · Long-term stability · Microstructural characterisation · Pd membrane · STEM analysis · Grain boundaries · Steam reforming · High angle grain boundaries · Long term stability · Microstructural changes · Microstructural characterisation · Microstructural stability · Molecular recombination · Pd membrane · Stem analysis · Methane · Palladium · Energy transfer · Membrane permeability · Membrane structure · Phase transition · Surface tension · Behavior · Formation · Holes · Hydrogen · Increments · Leakage · Membranes · Permeability
[Abstract]

10 Role of RhoA and Rho kinase in lysophosphatidic acid-induced endothelial barrier dysfunction.
article 2000    
Author: Nieuw Amerongen, G.P. van · Vermeer, M.A. · Hinsbergh, V.W. van
Keywords: Biology · Amides · Calcium · Cell Membrane Permeability · Cells, Cultured · Cyclic AMP · Cytoskeleton · Dose-Response Relationship, Drug · Endothelium, Vascular · Enzyme Activation · Enzyme Inhibitors · Horseradish Peroxidase · Humans · Intracellular Signaling Peptides and Proteins · Myosin Light Chains · Phosphatidic Acids · Phosphorylation · Protein-Serine-Threonine Kinases · Pyridines · rhoA GTP-Binding Protein · Thrombin · Time Factors · Umbilical Veins
[Abstract]

11 Monolayers of IEC-18 cells as an in vitro model for screening the passive transcellular and paracellular transport across the intestinal barrier: Comparison of active and passive transport with the human colon carcinoma Caco-2 cell line
article 2002    
Author: Versantvoort, C.H.M. · Ondrewater, R.C.A. · Duizer, E. · Sandt, J.J.M. van de · Gilde, A.J. · Groten, J.P.
Keywords: Caco-2 · Carrier-mediated transport · H+-di/tripeptide carrier · IEC-18 · Intestinal cell lines · MRP · P-Glycoprotein · acetylsalicylic acid · calcein · carrier protein · dinitrophenylglutathione · glucose derivative · glutathione derivative · glycoprotein P · glycylsarcosine · hydrocortisone · macrogol 4000 · mannitol · methylglucose · multidrug resistance protein · probenecid · propranolol · rhodamine 123 · salicylic acid · testosterone · unclassified drug · verapamil · vincristine · animal cell · article · cell membrane permeability · cell strain CACO 2 · cell transport · colon carcinoma · controlled study · drug transport · human · human cell · in vitro study · ion transport · model · nonhuman · priority journal · protein expression · rat · screening
[Abstract]

12 Tailoring fiber diameter in electrospun poly(ε-Caprolactone) scaffolds for optimal cellular infiltration in cardiovascular tissue engineering
article 2009    
Author: Balguid, A. · Mol, A. · Marion, M.H. van · Bank, R.A. · Bouten, C.V.C. · Baaijens, F.P.T.
Keywords: Biology · Biomedical Research · 4-hydroxybutyrate · Average fiber diameters · Caprolactone · Cardiovascular tissue engineerings · Cell attachments · Cell deliveries · Cell distributions · Cell ingrowths · Cell migrations · Cell penetrations · Cell sizes · Cellular infiltrations · Crucial parameters · Electrospun · Fiber diameters · Homogeneous tissues · Myofibroblasts · Nanofibrous scaffolds · Poly(glycolic acid) · Sufficient matrixes · Applications · Cell culture · Cells · Fibers · Tissue engineering · Scaffolds · polycaprolactone · polyglycolic acid · tissue scaffold · article · cell infiltration · cell membrane permeability · cell transport · cellular distribution · controlled study · fiber · human · human cell · human cell culture · myofibroblast · priority journal · tissue engineering · vein
[Abstract]

13 Effect of folate-binding protein on intestinal transport of folic acid and 5-methyltetrahydrofolate across Caco-2 cells
article 2005    
Author: Verwei, M. · Berg, H. van den · Havenaar, R. · Groten, J.P.
Keywords: Biology · Biomedical Research · Bioavailability · Caco-2 · Folate · Folate-binding protein · Intestinal transport · 5 methyltetrahydrofolic acid · caffeine · folate binding protein · folic acid · mannitol · article · cell growth · cell membrane permeability · controlled study · human · human cell · intestine absorption · intestine cell · monolayer culture · protein binding · Biological Transport · Caco-2 Cells · Carrier Proteins · Cell Culture Techniques · Chromatography, Gel · Folic Acid · Humans · Intestinal Absorption · Intestine, Small · Receptors, Cell Surface · Tetrahydrofolates · Time Factors · Bovinae
[Abstract]

14 Effects of cadmium chloride on the paracellular barrier function of intestinal epithelial cell lines
article 1999    
Author: Duizer, E. · Gilde, A.J. · Versantvoort, C.H.M. · Groten, J.P.
Keywords: Nutrition · Caco-2 · Cadmium · IEC-18 · Tight junction · Cadmium chloride · Macrogol 4000 · Annitol · Occludin · Uvomorulin · Animal tissue · Apical membrane · Cell junction · Cell viability · Cellular distribution · Cytotoxicity · Electric resistance · Human · Human tissue · Intestine mucosa permeability · Long term exposure · Molecular size · Nonhuman · Tight junction · Transcytosis · Animals · Caco-2 Cells · Cadherins · Cadmium Chloride · Cadmium Radioisotopes · Cell Membrane Permeability · Cell Survival · Cells, Cultured · Epithelial Cells · Humans · Ileum · Intestinal Absorption · Mannitol · Membrane Proteins · Phosphoproteins · Polyethylene Glycols · Rats · Tight Junctions · Animalia
[Abstract]

15 Physicochemical properties and transport of steroids across Caco-2 cells
article 2003    
Author: Faassen, F. · Kelder, J. · Lenders, J. · Onderwater, R. · Vromans, H.
Keywords: Drugs · Physiological Sciences · Absorption · Caco-2 permeability · Physicochemical properties · Steroids · 17alpha hydroxy 11 methylene 19 norpregna 4,15 dien 20 yn 3 one · aldosterone · cefalexin · cortisone · dexamethasone · estradiol · ethinylestradiol · etonogestrel · gestodene · glucose · hydrocortisone · macrogol 4000 · mannitol · nandrolone · norethisterone · norgestrel · org 32540 · org 34694 · org 36410 · org 4060 · org 4325 · org om 08 · phenazone · prednisolone · progesterone · spironolactone · steroid · testosterone · verapamil · article · calculation · cell membrane permeability · cell strain CACO 2 · controlled study · drug absorption · drug surveillance program · drug transport · human · human cell · molecular weight · physical chemistry · priority journal · Biological Transport · Caco-2 Cells · Chemistry, Physical · Humans · Solubility · Steroids
[Abstract]

16 An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers
article 2006    
Author: Schutte, M.E. · Freidig, A.P. · Sandt, J.J.M. van de · Alink, G.M. · Rietjens, I.M.C.M. · Groten, J.P.
Keywords: Biology · Biomedical Research · ABC transporter · Caco-2 · Flavonoid · Heterocyclic amine · In silico · 2 amino 1 methyl 6 phenylimidazo[4,5 b]pyridine · breast cancer resistance protein · chrysoeriol · elacridar · flavone · flavonoid · kaempferol · luteolin · morin · multidrug resistance protein · myricetin · naringenin · quercetin · robinetin · taxifolin · unclassified drug · verlukast · absorption · apical membrane · article · cell strain CACO 2 · computer model · controlled study · drug effect · human · human cell · Acridines · ATP-Binding Cassette Transporters · Biological Transport, Active · Caco-2 Cells · Carcinogens · Cell Membrane Permeability · Diffusion · Dose-Response Relationship, Drug · Flavanones · Flavonoids · Humans · Imidazoles · Intestinal Absorption · Intestinal Mucosa · Kinetics · Membrane Transport Proteins · Models, Biological · Multidrug Resistance-Associated Proteins · Neoplasm Proteins · P-Glycoprotein · Propionates · Quinolines · Reproducibility of Results · Tetrahydroisoquinolines
[Abstract]

17 Expression of cGMP-dependent protein kinase I and phosphorylation of its substrate, vasodilator-stimulated phosphoprotein, in human endothelial cells of different origin
article 1995    
Author: Draijer, R. · Vaandrager, A.B. · Nolte, C. · Jonge, H.R. de · Walter, U. · Hinsbergh, V.W.M. van
Keywords: Biology · aortic endothelial cells · cGMP · endothelial contraction · microvascular endothelial cells · permeability · 8 (4 chlorophenylthio) cyclic GMP · calcium ion · cyclic GMP · cyclic GMP derivative · fura 2 · horseradish peroxidase · phosphoprotein · protein kinase · thrombin · unclassified drug · vasodilator stimulated phosphoprotein · aorta · article · calcium cell level · cell membrane permeability · endothelium cell · human · human cell · iliac artery · iliac vein · prepuce · priority journal · protein phosphorylation · umbilical vein · vascular endothelium · Aorta · Autoradiography · Blotting, Northern · Calcium Channels · Capillary Permeability · Cell Adhesion Molecules · Cells, Cultured · Comparative Study · Cyclic GMP · Cyclic GMP-Dependent Protein Kinases · Cytoplasm · Endothelium, Vascular · Enzyme Activation · Hemostasis · Human · Iliac Artery · Iliac Vein · Immunohistochemistry · Microcirculation · Microfilament Proteins · Models, Biological · Phosphoproteins · Phosphorylation · Platelet Aggregation Inhibitors · RNA · Support, Non-U.S. Gov't · Thionucleotides · Thrombin · Time Factors · Umbilical Veins
[Abstract]

18 GIT1 Mediates Thrombin Signaling in Endothelial Cells: Role in Turnover of RhoA-Type Focal Adhesions
article 2004    
Author: Nieuw Amerongen, G.P. van · Natarajan, K. · Yin, G. · Hoefen, R.J. · Osawa, M. · Haendeler, J. · Ridley, A.J. · Fujiwara, K. · Hinsbergh, V.W.M. van · Berk, B.C.
Keywords: Biology · Biomedical Research · Contractility · Endothelium · Focal adhesion kinase · Thrombin · 4 (1 aminoethyl) n (4 pyridyl)cyclohexanecarboxamide · antisense oligonucleotide · focal adhesion kinase · G protein coupled receptor kinase · G protein coupled receptor kinase interacting protein · GIT1 protein · guanosine triphosphatase · protein tyrosine kinase · Rho kinase · RhoA guanine nucleotide binding protein · thrombin · unclassified drug · vinculin · Adenovirus · animal cell · article · cell migration · cell shape · cell structure · cellular distribution · controlled study · depletion · endothelium cell · enzyme activation · enzyme metabolism · enzyme phosphorylation · enzyme substrate · focal adhesion · genetic transfection · human · human cell · membrane permeability · negative feedback · nonhuman · priority journal · protein function · protein localization · protein phosphorylation · protein protein interaction · protein transport · regulatory mechanism · signal transduction · umbilical vein · Adaptor Proteins, Signal Transducing · Amides · Animals · Aorta · Cattle · Cell Cycle Proteins · Cell Size · Cells, Cultured · Endothelial Cells · Endothelium, Vascular · Enzyme Inhibitors · Feedback, Biochemical · Focal Adhesion Kinase 1 · Focal Adhesion Protein-Tyrosine Kinases · Focal Adhesions · GTPase-Activating Proteins · Humans · Oligodeoxyribonucleotides, Antisense · Phosphoproteins · Phosphorylation · Protein Processing, Post-Translational · Protein Transport · Protein-Tyrosine Kinases · Proto-Oncogene Proteins pp60(c-src) · Pyridines · rac GTP-Binding Proteins · rhoA GTP-Binding Protein · RNA, Small Interfering · Signal Transduction · Thrombin · Transduction, Genetic · Transfection · Umbilical Veins · Vinculin
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 18 of 18 found. | Sort by date