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1 Effects of consumption of Brussels sprouts on intestinal and lymphocytic glutathione S-transferases in humans
article 1995    
Author: Nijhoff, W.A. · Grubben, M.J.A.L. · Nagengast, F.M. · Jansen, J.B.M.J. · Verhagen, H. · Poppel, G. van · Peters, W.H.M.
Keywords: Biology · Adult · Brassica · Cross-Over Studies · Duodenum · Energy Intake · Enzyme Induction · Female · Glucosinolates · Glutathione · Glutathione Transferase · Human · Intestines · Isoenzymes · Lymphocytes · Male · Metabolic Detoxication, Drug · Rectum · Thiocyanates
[Abstract]

2 Glutathione conjugation as a bioactivation reaction
article 2000    
Author: Bladeren, P.J. van
Keywords: Nutrition · Bioactivation · Glutathione conjugates · Glutathione S-transferases · Cysteine · Glutathione · Glutathione transferase · Lyase · Catalysis · Chemical binding · Chemical reaction · Chromosomal localization · Conjugation · Covalent bond · Detoxification · Enzyme activation · Enzyme activity · Enzyme induction · Enzyme inhibition · Enzyme mechanism · Gene location · Genetic polymorphism · Human · Nonhuman · Protein expression · Reaction analysis · Reduction · Animals · Biotransformation · Carbon-Sulfur Lyases · Enzyme Induction · Glutathione · Glutathione Transferase · Humans · Metabolic Detoxication, Drug · Oxidation-Reduction · Xenobiotics
[Abstract]

3 Glutathione conjugation of the cytostatic drug ifosfamide and the role of human glutathione S-transferases
article 1995    
Author: Dirven, H.A.A.M. · Megens, L. · Oudshoorn, M.J. · Dingemanse, M.A. · Ommen, B. van · Bladeren, P.J. van
Keywords: Nutrition · Glutathione · Glutathione transferase · Ifosfamide · Cancer chemotherapy · Drug conjugation · Drug detoxification · Drug resistance · Enzyme activity · Human · Human tissue · Leukemia · Lymphoma · Solid tumor · Antineoplastic Agents, Alkylating · Biotransformation · Chromatography, High Pressure Liquid · Drug Resistance, Neoplasm · Glutathione · Glutathione Transferase · Human · Ifosfamide · Isoenzymes · Magnetic Resonance Spectroscopy · Metabolic Detoxication, Drug · Spectrometry, Mass, Fast Atom Bombardment · Support, Non-U.S. Gov't
[Abstract]

4 A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat
article 2008    
Author: Punt, A. · Freidig, A.P. · Delatour, T. · Scholz, G. · Boersma, M.G. · Schilter, B. · Bladeren, P.J. van · Rietjens, I.M.C.M.
Keywords: Biology · Biomedical Research · Bioactivation · Detoxification · Estragole · In vitro · PBPK · Rat · 1' hydroxyestragole glucuronide · 1' sulfooxyestragole · Benzene derivative · Chavicol · Estragole · Glucuronide · Phenol derivative · Unclassified drug · Animal tissue · Arterial blood · Body fat · Controlled study · Detoxification · In vitro study · Kinetics · Liver · Nonhuman · Partition coefficient · Rat · Tissue perfusion · Venous blood · Allyl Compounds · Animals · Anisoles · Carcinogens · Dose-Response Relationship, Drug · Female · Glucuronides · Kidney · Lung · Male · Metabolic Detoxication, Drug · Models, Biological · Phenols · Rats · Rats, Sprague-Dawley · Rats, Wistar · Sulfones · Tissue Distribution · Rattus · Food and Nutrition · Healthy Living
[Abstract]

5 Recombinant Saccharomyces cerevisiae expressing P450 in artificial digestive systems : A model for biodetoxication in the human digestive environment
article 2003    
Author: Blanquet, S. · Meunier, J.P. · Minekus, M. · Marol-Bonnin, S. · Alric, M.
Keywords: Health Nutrition · Physiological Sciences · Digestive system · Disease control · Microbiology · Microorganisms · Biodrugs · Yeast · Cinnamate 4 monooxygenase · Cinnamic acid · cytochrome P450 · Oxygenase · Para coumaric acid · Unclassified drug · Biotechnology · Drug development · Microbiology · Article · Biotransformation · Computer simulation · Detoxification · Digestion · Digestive system · Duodenum · Enzyme activity · Gastrointestinal tract · Ileum · Incubation time · Intestine secretion · Jejunum · Quantitative analysis · Saccharomyces cerevisiae · Small intestine · Stomach secretion · Survival rate · Yeast · Genetic Engineering · Helianthus · Humans · Metabolic Detoxication, Drug · Mixed Function Oxygenases · Models, Biological · Saccharomyces cerevisiae · Trans-Cinnamate 4-Monooxygenase · Saccharomyces cerevisiae
[PDF] [Abstract]

6 Disposition of 14C-α-cyclodextrin in germ-free and conventional rats
article 2004    
Author: Ommen, B. van · Bie, A.T.H.J. de · Bär, A.
Keywords: Biology · Physiological Sciences · alpha cyclodextrin · carbon 14 · alpha cyclodextrin derivative · alpha-cyclodextrin · carbon · cyclodextrin · animal experiment · animal tissue · article · blood analysis · carcass · controlled study · dietary fiber · female · fermentation · gastrointestinal tract · germfree animal · high performance liquid chromatography · intestine flora · isotope labeling · kidney tubule excretion · lung alveolus carbon dioxide tension · male · metabolic regulation · nonhuman · priority journal · radioisotope distribution · rat · rat strain · small intestine absorption · species comparison · stomach content · animal · blood · drug detoxification · intravenous drug administration · oral drug administration · tissue distribution · urine · Wistar rat · Mammalia · Microbiota · Rattus norvegicus · Administration, Oral · alpha-Cyclodextrins · Animals · Carbon Radioisotopes · Cyclodextrins · Female · Germ-Free Life · Injections, Intravenous · Male · Metabolic Detoxication, Drug · Rats · Rats, Wistar · Tissue Distribution
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 6 of 6 found. | Sort by date