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1 Stimulation of the in Vivo Production of Very Low Density Lipoproteins by Apolipoprotein E Is Independent of the Presence of the Low Density Lipoprotein Receptor
article 2001    
Author: Teusink, B. · Mensenkamp, A.R. · Boom, H. van der · Kuipers, F. · Dijk, K.W. van · Havekes, L.M.
Keywords: Animalia · Gillia · Animals · Apolipoproteins E · Lipoproteins, VLDL · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Receptors, LDL
[PDF] [Abstract]

2 Severe learning deficits in apolipoprotein E-knockout mice in a water maze task
article 1997    
Author: Oitzl, M.S. · Mulder, M. · Lucassen, P.J. · Havekes, L.M. · Grootendorst, J. · Kloet, E.R. de
Keywords: Alzheimer' s disease · Animals · Apolipoproteins E · Learning Disorders · Male · Maze Learning · Mice · Mice, Knockout · Motor Activity · Reference Values · Swimming
[Abstract]

3 Balancing the Th1/Th2 concept in multiple sclerosis
article 1998    
Author: Laman, J.D. · Thompson, E.J. · Kappos, L.
Keywords: Health · Animals · Antigen Presentation · Biological Markers · Callithrix · Cytokines · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Humans · Mice · Mice, Knockout · Multiple Sclerosis · Th1 Cells · Th2 Cells

4 Protection from obesity in mice lacking the VLDL receptor
article 2001    
Author: Goudriaan, J.R. · Tacken, P.J. · Dahlmans, V.E.H. · Gijbels, M.J.J. · Dijk, K.W. van · Havekes, L.M. · Jong, M.C.
Keywords: Adipose Tissue · Animals · Diet, Atherogenic · Fatty Acids · Glucose Tolerance Test · Insulin Resistance · Mice · Mice, Knockout · Mice, Obese · Mice, Transgenic · Obesity · Receptors, LDL · Triglycerides · Weight Gain
[Abstract]

5 Critical role of tissue kallikrein in vessel formation and maturation : Implications for therapeutic revascularization
article 2009    
Author: Stone, O.A. · Richer, C. · Emanueli, C. · Weel, V. van · Quax, P.H.A. · Katare, R. · Kraenkel, N. · Campagnolo, P. · Barcelos, L.S. · Siragusa, M. · Sala-Newby, G.B. · Baldessari, D. · Mione, M. · Vincent, M.P. · Benest, A.V. · Al Haj Zen, A. · Gonzalez, J. · Bates, D.O. · Alhenc-Gelas, F. · Madeddu, P.
Keywords: Biology · Biomedical Research · Angiogenesis · Gene mutations · Gene therapy · Metalloproteinases · Animals · Hindlimb · Humans · Ischemia · Kallikrein-Kinin System · Male · Matrix Metalloproteinase 9 · Mice · Mice, Knockout · Neovascularization, Physiologic · Rats · Splanchnic Circulation · Tissue Kallikreins · Wound Healing · Zebrafish
[Abstract]

6 Binding of β-VLDL to heparan sulfate proteoglycans requires lipoprotein lipase, whereas apoE only modulates binding affinity
article 1999    
Author: Beer, F. de · Hendriks, W.L. · Vark, L.C. van · Kamerling, S.W.A. · Dijk, K.W. van · Hofker, M.H. · Smelt, A.H.M. · Havekes, L.M.
Keywords: Biology · β-VLDL · apoE · Heparan sulfate proteoglycans · Lipoprotein lipase · Animals · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Binding, Competitive · Cell Line · Cholesterol, VLDL · Heparan Sulfate Proteoglycans · Iodine Radioisotopes · Lipoprotein Lipase · Macrophages · Mice · Mice, Knockout
[Abstract]

7 Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver
article 1999    
Author: Mensenkamp, A.R. · Jong, M.C. · Goor, H. van · Luyn, M.J.A. van · Bloks, V. · Havinga, R. · Voshol, P.J. · Hofker, M.H. · Dijk, K.W. van · Havekes, L.M. · Kuipers, F.
Keywords: Biology · Animals · Apolipoproteins E · Cells, Cultured · Cholesterol · Crosses, Genetic · Fatty Acids, Nonesterified · Glycerol · Homeostasis · Humans · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Knockout · Mice, Transgenic · Microscopy, Immunoelectron · Phytosterols · Sitosterols · Sterols · Triglycerides · Tritium
[PDF] [Abstract]

8 Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice
article 1999    
Author: Winther, M.P.J. de · Gijbels, M.J.J. · Dijk, K.W. van · Gorp, P.J.J. van · Suzuki, H. · Kodama, T. · Frants, R.R. · Havekes, L.M. · Hofker, M.H.
Keywords: Biology · Apolipoprotein E · Atherosclerosis · Mouse models · Animals · Aorta, Thoracic · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Diet, Atherogenic · Female · Humans · Male · Membrane Proteins · Mice · Mice, Knockout · Mice, Transgenic · Receptors, Immunologic · Receptors, Lipoprotein · Receptors, Scavenger · Risk Factors · Scavenger Receptors, Class B
[Abstract]

9 Hyperlipidemia of ApoE2(Arg158-Cys) and ApoE3-Leiden transgenic mice is modulated predominantly by LDL receptor expression
article 1999    
Author: Dijk, K.W. van · Vlijmen, B.J.M. van · Winther, M.P.J. de · Hof, B. van 't · Zee, A. van der · Boom, H. van der · Havekes, L.M. · Hofker, M.H.
Keywords: Biology · Apolipoprotein E · Hypertriglyceridemia · LDL receptor · LDL receptor-related protein · VLDL triglyceride lipolysis · Animals · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Cholesterol, VLDL · Gene Expression · Hypertriglyceridemia · Lipolysis · Mice · Mice, Knockout · Point Mutation · Receptors, LDL · Triglycerides
[Abstract]

10 Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-Leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor
article 1998    
Author: Dijk, K.W. van · Vlijmen, B.J.M. van · Zee, A. van der · Hof, B. van 't · Boom, H. van der · Kobayashi, K. · Chan, L. · Havekes, L.M. · Hofker, M.H.
Keywords: Health · ApoE variants · Atherosclerosis · Gene therapy · VLDL receptor · Adenoviridae · Animals · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Cholesterol · Female · Gene Transfer Techniques · Humans · Hypercholesterolemia · Mice · Mice, Knockout · Mice, Transgenic · Receptors, LDL · Triglycerides
[Abstract]

11 Cafestol increases serum cholesterol levels in apolipoprotein E*3- leiden transgenic mice by suppression of bile acid synthesis
article 2000    
Author: Post, S.M. · Roos, B.de · Vermeulen, M. · Afman, L. · Jong, M.C. · Dahlmans, V.E.H. · Havekes, L.M. · Stellaard, F. · Katan, M.B. · Princen, H.M.G.
Keywords: Biology · Animals · Apolipoprotein E3 · Apolipoproteins E · Bile Acids and Salts · Cholesterol · Diet · Diterpenes · Feces · Female · Lipid Metabolism · Lipoproteins · Lipoproteins, IDL · Lipoproteins, VLDL · Liver · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Receptors, LDL
[Abstract]

12 Apolipoprotein E2 (Lys146→Gln) causes hypertriglyceridemia due to an apolipoprotein E variant-specific inhibition of lipolysis of very low density lipoproteins-triglycerides
article 2000    
Author: Beer, F. de · Dijk, K.W. van · Jong, M.C. · Vark, L.C. van · Zee, A. van der · Hofker, M.H. · Fallaux, F.J. · Hoeben, R.C. · Smelt, A.H.M. · Havekes, L.M.
Keywords: Adenoviridae · Alleles · Animals · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Gene Expression · Gene Transfer Techniques · Humans · Hydrolysis · Hyperlipoproteinemia Type III · Hypertriglyceridemia · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · Point Mutation · RNA, Messenger · Triglycerides
[Abstract]

13 Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knockout mice
article 2000    
Author: Herijgers, N. · Winther, M.P.J. de · Eck, M. van · Havekes, L.M. · Hofker, M.H. · Hoogerbrugge, P.M. · Berkel, T.J.C. van
Keywords: Acetylation · Animals · Arteriosclerosis · Bone Marrow Cells · Bone Marrow Transplantation · Cell Adhesion Molecules · Female · Humans · Lipoproteins · Lipoproteins, LDL · Macrophages, Peritoneal · Mice · Mice, Knockout · Mice, Transgenic · Receptors, Immunologic · Receptors, LDL · Receptors, Scavenger · Scavenger Receptors, Class A
[PDF] [Abstract]

14 Domains of apolipoprotein E contributing to triglyceride and cholesterol homeostasis in vivo. Carboxyl-terminal region 203-299 promotes hepatic very low density lipoprotein-triglyceride secretion
article 2001    
Author: Kypreos, K.E. · Dijk, K.W. van · Zee, A. van der · Havekes, L.M. · Zannis, V.I.
Keywords: Biology · Adenoviridae · Animalia · Adenoviridae · Animals · Apolipoprotein E4 · Apolipoproteins E · Base Sequence · Cholesterol · Chromatography, Liquid · DNA Primers · Female · Homeostasis · Humans · Liver · Mice · Mice, Knockout · RNA, Messenger · Triglycerides · Tumor Cells, Cultured
[PDF] [Abstract]

15 In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2(Arg-158 → Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice
article 1996    
Author: Vlijmen, B.J.M. van · Dijk, K.W. van · Hof, H.B. van 't · Gorp, P.J.J. van · Zee, A. van der · Boom, H. van der · Breuer, M.L. · Hofker, M.H. · Havekesf, L.M.
Keywords: Animals · Apolipoproteins E · Arginine · Cells, Cultured · Cysteine · Genes, Dominant · Heymann Nephritis Antigenic Complex · Hyperlipoproteinemias · Lipoproteins, LDL · Lipoproteins, VLDL · Membrane Glycoproteins · Mice · Mice, Knockout · Mice, Transgenic · Receptors, LDL · Adenoviridae · Animalia · Mus musculus
[PDF] [Abstract]

16 Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice
article 2001    
Author: Jong, M.C. · Rensen, P.C.N. · Dahlmans, V.E.H. · Boom, H. van der · Berkel, T.J.C. van · Havekes, L.M.
Keywords: Animals · Apolipoprotein C-III · Apolipoproteins C · Apolipoproteins E · Chylomicrons · Crosses, Genetic · Female · Gene Deletion · Hydrolysis · Lipoprotein Lipase · Lipoproteins, VLDL · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Time Factors · Triglycerides
[PDF] [Abstract]

17 Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo
article 2008    
Author: Haan, W. de · Out, R. · Berbée, J.F.P. · Hoogt, C.C. van der · Dijk, K.W.v. · Berkel, T.J.C. van · Romijn, J.A. · Wouter Jukema, J. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Physiological Sciences · High density lipoprotein · Oxidized LDL · SR-BI · Transgenic mice · cholesterol ester · high density lipoprotein cholesterol · scavenger receptor BI · Adenovirus · animal cell · cholesterol metabolism · dose response · in vivo study · liver cell · mouse · nonhuman · particle size · protein expression · Adenoviridae · Animals · Apolipoprotein C-I · Cholesterol, HDL · Gene Transfer Techniques · Hepatocytes · Humans · Mice · Mice, Knockout · Scavenger Receptors, Class B · Adenoviridae · Murinae · Mus · Mus musculus
[Abstract]

18 Natural killer cells and CD4+ T-cells modulate collateral artery development
article 2007    
Author: Weel, V. van · Toes, R.E.M. · Seghers, L. · Deckers, M.M.L. · Vries, M.R. de · Eilers, P.H. · Sipkens, J. · Schepers, A. · Eefting, D. · Hinsbergh, V.W.M. van · Bockel, J.H. van · Quax, P.H.A.
Keywords: Biomedical Research · Angiogenesis · Animal models of human disease · Peripheral vascular disease · biological marker · CD3 antigen · CD4 antigen · vascularization · Animals · Arterial Occlusive Diseases · CD4-Positive T-Lymphocytes · Collateral Circulation · Disease Models, Animal · Femoral Artery · Hindlimb · Ischemia · Killer Cells, Natural · Mice · Mice, Inbred BALB C · Mice, Knockout · Neovascularization, Physiologic
[Abstract]

19 Pathogenic sequence for dissecting aneurysm formation in a hypomorphic polycystic kidney disease 1 mouse model
article 2007    
Author: Hassane, S. · Claij, N. · Lantinga-van Leeuwen, I.S. · Munsteren, J.C. van · Lent, N. van · Hanemaaijer, R. · Breuning, M.H. · Peters, D.J.M. · Ruiter, M.C. de
Keywords: Biology · Biomedical Research · Aorta · Dissecting aneurysm · Extracellular matrix · Pkd1 · Polycystic kidney disease · Aneurysm, Dissecting · Animals · Aorta · Aortic Aneurysm · Disease Models, Animal · Disease Progression · Endothelial Cells · Extracellular Matrix · Genotype · Mice · Mice, Inbred C57BL · Mice, Knockout · Mutation · Myocytes, Smooth Muscle · Phenotype · Polycystic Kidney Diseases · RNA, Messenger · Severity of Illness Index · TRPP Cation Channels · Tunica Intima · Tunica Media
[PDF] [Abstract]

20 Apolipoprotein CI aggravates atherosclerosis development in ApoE-knockout mice despite mediating cholesterol efflux from macrophages
article 2007    
Author: Westerterp, M. · Eck, M. van · Haan, W. de · Offerman, E.H. · Berkel, T.J.C. van · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · ApoCI · Cholesterol efflux · Hyperlipidemia · Macrophages · Transgenic mice · Triacylglycerol · Adipose tissue · Aorta root · Artery wall · Atherosclerosis · Protein expression · Statistical significance · Triacylglycerol blood level · Animals · Apolipoprotein C-I · Apolipoproteins E · Atherosclerosis · Bone Marrow Cells · Bone Marrow Transplantation · Cholesterol · Female · Gene Expression Regulation · Liver · Macrophages · Male · Mice · Mice, Knockout · Mice, Transgenic
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 59 found. Next | Sort by date