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1 Role of apoCs in lipoprotein metabolism : Functional differences between ApoC1, ApoC2, and ApoC3
article 1999    
Author: Jong, M.C. · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · Apolipoproteins · Lipoprotein lipase · Lipoproteins, VLDL · Mice, transgenic · Animals · Apolipoprotein C-I · Apolipoprotein C-II · Apolipoprotein C-III · Apolipoproteins C · Humans · Lipoproteins · Mice · Mice, Transgenic · Mutation
[Abstract]

2 Effects of fenofibrate on hyperlipidemia and postprandial triglyceride metabolism in human apolipoprotein C1 transgenic mice
article 1998    
Author: Jong, M.C. · Dahlmans, V.E.H. · Princen, H.M.G. · Hofker, M.H. · Havekes, L.M.
Keywords: Health · Apo C · LDL-receptor · Transgenic mice · Triglycerides · Animals · Antilipemic Agents · Apolipoproteins C · Humans · Hyperlipidemias · Mice · Mice, Transgenic · Procetofen · Triglycerides
[Abstract]

3 Transgenic mouse models to study the role of APOE in hyperlipidemia and atherosclerosis
article 1998    
Author: Hofker, M.H. · Vlijmen, B.J.M. van · Havekes, L.M.
Keywords: Health · APOE · Apolipoprotein · Cholesterol · Gene targeting · Lipoprotein · Triglyceride · Animals · Apolipoproteins E · Arteriosclerosis · Disease Models, Animal · Humans · Hyperlipidemias · Mice · Mice, Transgenic
[Abstract]

4 Atherosclerosis in APOE(*)3-Leiden transgenic mice from proliferative to atheromatous stage
article 1999    
Author: Lutgens, E. · Daemen, M. · Kockx, M. · Doevendans, P. · Hofker, M. · Havekes, L. · Wellens, H. · Muinck, E.D. de
Keywords: Biology · Apoptosis · Atherosclerosis · Genetics · Animals · Apolipoprotein E3 · Apolipoproteins E · Apoptosis · Arteriosclerosis · Diet, Atherogenic · Disease Models, Animal · Disease Progression · DNA · Female · Foam Cells · Male · Mice · Mice, Transgenic · Phenotype
[Abstract]

5 Use of transgenic mice in lipoprotein metabolism and atherosclerosis research
article 1997    
Author: Havekes, L.M. · Vlijmen, B.J.M. van · Jong, M.C. · Dijk, K.W. van · Hofker, M.H.
Keywords: Biology · Age Factors · Animals · Apolipoprotein E3 · Apolipoproteins C · Apolipoproteins E · Arteriosclerosis · Cholesterol · Female · Humans · Lipids · Lipoproteins · Lipoproteins, VLDL · Male · Mice · Mice, Transgenic · Sex Factors · Animalia · Mus musculus
[Abstract]

6 Protection from obesity in mice lacking the VLDL receptor
article 2001    
Author: Goudriaan, J.R. · Tacken, P.J. · Dahlmans, V.E.H. · Gijbels, M.J.J. · Dijk, K.W. van · Havekes, L.M. · Jong, M.C.
Keywords: Adipose Tissue · Animals · Diet, Atherogenic · Fatty Acids · Glucose Tolerance Test · Insulin Resistance · Mice · Mice, Knockout · Mice, Obese · Mice, Transgenic · Obesity · Receptors, LDL · Triglycerides · Weight Gain
[Abstract]

7 Mice expressing only the mutant APOE3Leiden gene show impaired VLDL secretion
article 2001    
Author: Mensenkamp, A.R. · Teusink, B. · Baller, J.F.W. · Wolters, H. · Havinga, R. · Dijk, K.W. van · Havekes, L.M. · Kuipers, F.
Keywords: Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Fatty Liver · Lipid Metabolism · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Protein Isoforms · RNA, Messenger · Triglycerides
[Abstract]

8 Hyperlipidemia in APOE2 transgenic mice is ameliorated by a truncated apoE variant lacking the C-terminal domain
article 2003    
Author: Gerritsen, G. · Kypreos, K.E. · Zee, A. van der · Teusink, B. · Zannis, V.I. · Havekes, L.M. · Dijk, K.W. van
Keywords: Biology · Adenoviridae · Animals · Apolipoprotein E2 · Apolipoprotein E4 · Apolipoproteins E · Cholesterol · Humans · Hyperlipidemias · Lipids · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Protein Isoforms · Protein Structure, Tertiary · Triglycerides
[PDF] [Abstract]

9 Accelerated atherosclerosis and calcification in vein grafts: A study in APOE*3 Leiden transgenic mice
article 2002    
Author: Lardenoye, J.H.P. · Vries, M.R. de · Löwik, C.W.G.M. · Xu, Q. · Dhore, C.R. · Cleutjens, J.P.M. · Hinsbergh, V.W.M. van · Bockel, J.H. van · Quax, P.H.A.
Keywords: Animals · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Calcinosis · Foam Cells · Graft Rejection · Hypercholesterolemia · Kinetics · Lipids · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Veins
[Abstract]

10 Long- and medium-term carcinogenicity studies in animals and short-term genotoxicity tests.
article 1999    
Author: Feron, V.J. · Schwarz, M. · Hemminki, K. · Krewski, D.
Keywords: Toxicology · biological marker · mutagenic agent · animal · bioassay · carcinogen testing · human · methodology · mouse · review · species difference · time · transgenic mouse · Animals · Biological Assay · Biological Markers · Carcinogenicity Tests · Humans · Mice · Mice, Transgenic · Mutagens · Research Design · Species Specificity · Time Factors

11 Germ cell mutagenesis in lambdalacZ transgenic mice treated with ethylnitrosourea : comparison with specific-locus test
article 1995    
Author: Delft, J.H.M. van · Baan, R.A.
Keywords: Biology · Animal · Comparative Study · DNA · Dose-Response Relationship, Drug · Ethylnitrosourea · Guanidine · Guanidines · Lac Operon · Male · Mice · Mice, Transgenic · Mutagenesis · Mutagenicity Tests · Spermatogenesis · Spermatozoa · Support, Non-U.S. Gov't · Time Factors
[Abstract]

12 Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver
article 1999    
Author: Mensenkamp, A.R. · Jong, M.C. · Goor, H. van · Luyn, M.J.A. van · Bloks, V. · Havinga, R. · Voshol, P.J. · Hofker, M.H. · Dijk, K.W. van · Havekes, L.M. · Kuipers, F.
Keywords: Biology · Animals · Apolipoproteins E · Cells, Cultured · Cholesterol · Crosses, Genetic · Fatty Acids, Nonesterified · Glycerol · Homeostasis · Humans · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Knockout · Mice, Transgenic · Microscopy, Immunoelectron · Phytosterols · Sitosterols · Sterols · Triglycerides · Tritium
[PDF] [Abstract]

13 Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice
article 1999    
Author: Winther, M.P.J. de · Gijbels, M.J.J. · Dijk, K.W. van · Gorp, P.J.J. van · Suzuki, H. · Kodama, T. · Frants, R.R. · Havekes, L.M. · Hofker, M.H.
Keywords: Biology · Apolipoprotein E · Atherosclerosis · Mouse models · Animals · Aorta, Thoracic · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Diet, Atherogenic · Female · Humans · Male · Membrane Proteins · Mice · Mice, Knockout · Mice, Transgenic · Receptors, Immunologic · Receptors, Lipoprotein · Receptors, Scavenger · Risk Factors · Scavenger Receptors, Class B
[Abstract]

14 In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE
article 1999    
Author: Dijk, K.W. van · Vlijmen, B.J.M. van · Hof, H.B. van 't · Zee, A. van der · Santamarina-Fojo, S. · Berkel, T.J.C. van · Havekes, L.M. · Hofker, M.H.
Keywords: Health · Adenovirus-mediated gene transfer · Hepatic VLDL triglyceride production · Hypertriglyceridemia · LDL receptor-related protein · VLDL-triglyceride lipolysis · Adenovirus · Adenoviridae · Animals · Apolipoproteins E · Cholesterol · Female · Humans · Immunohistochemistry · Lipolysis · Lipoprotein Lipase · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Receptors, LDL · Transfection · Triglycerides
[PDF] [Abstract]

15 Cafestol increases serum cholesterol levels in apolipoprotein E*3- leiden transgenic mice by suppression of bile acid synthesis
article 2000    
Author: Post, S.M. · Roos, B.de · Vermeulen, M. · Afman, L. · Jong, M.C. · Dahlmans, V.E.H. · Havekes, L.M. · Stellaard, F. · Katan, M.B. · Princen, H.M.G.
Keywords: Biology · Animals · Apolipoprotein E3 · Apolipoproteins E · Bile Acids and Salts · Cholesterol · Diet · Diterpenes · Feces · Female · Lipid Metabolism · Lipoproteins · Lipoproteins, IDL · Lipoproteins, VLDL · Liver · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Receptors, LDL
[Abstract]

16 Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knockout mice
article 2000    
Author: Herijgers, N. · Winther, M.P.J. de · Eck, M. van · Havekes, L.M. · Hofker, M.H. · Hoogerbrugge, P.M. · Berkel, T.J.C. van
Keywords: Acetylation · Animals · Arteriosclerosis · Bone Marrow Cells · Bone Marrow Transplantation · Cell Adhesion Molecules · Female · Humans · Lipoproteins · Lipoproteins, LDL · Macrophages, Peritoneal · Mice · Mice, Knockout · Mice, Transgenic · Receptors, Immunologic · Receptors, LDL · Receptors, Scavenger · Scavenger Receptors, Class A
[PDF] [Abstract]

17 HLA-B27 as a relative risk factor in ankylosing enthesopathy in transgenic mice
article 1995    
Author: Weinreich, S. · Eulderink, F. · Capkova, J. · Pla, M. · Gaede, K. · Heesemann, J. · Alphen, L. van · Zurcher, C. · Hoebe-Hewryk, B. · Kievits, F. · Ivanyi, P.
Keywords: Biology · HLA B27 antigen · Age Factors · Animal · Biological Markers · Cyclosporine · Female · H-2 Antigens · HLA-B27 Antigen · Housing, Animal · Interleukin-6 · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Rheumatic Diseases · Risk Factors · Sex Factors
[Abstract]

18 In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2(Arg-158 → Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice
article 1996    
Author: Vlijmen, B.J.M. van · Dijk, K.W. van · Hof, H.B. van 't · Gorp, P.J.J. van · Zee, A. van der · Boom, H. van der · Breuer, M.L. · Hofker, M.H. · Havekesf, L.M.
Keywords: Animals · Apolipoproteins E · Arginine · Cells, Cultured · Cysteine · Genes, Dominant · Heymann Nephritis Antigenic Complex · Hyperlipoproteinemias · Lipoproteins, LDL · Lipoproteins, VLDL · Membrane Glycoproteins · Mice · Mice, Knockout · Mice, Transgenic · Receptors, LDL · Adenoviridae · Animalia · Mus musculus
[PDF] [Abstract]

19 An extrahepatic receptor-associated protein-sensitive mechanism is involved in the metabolism of triglyceride-rich lipoproteins
article 1999    
Author: Vlijmen, B.J.M. van · Rohlmann, A. · Page, S.T. · Bensadoun, A. · Bos, I.S.T. · Berkel, T.J.C. van · Havekes, L.M. · Herz, J.
Keywords: Animals · Binding Sites · Cholesterol · Chylomicrons · Detergents · Gene Transfer Techniques · Heymann Nephritis Antigenic Complex · Immunoblotting · LDL-Receptor Related Protein 1 · Lipase · Lipoprotein Lipase · Liver · Membrane Glycoproteins · Mice · Mice, Transgenic · Polyethylene Glycols · Rats · Receptors, Immunologic · Receptors, LDL · Time Factors · Transfection · Triglycerides
[PDF] [Abstract]

20 Reversal of hypercholesterolemia in apolipoprotein E2 and apolipoprotein E3-Leiden transgenic mice by adenovirus-mediated gene transfer of the VLDL receptor
article 1998    
Author: Dijk, K.W. van · Vlijmen, B.J.M. van · Zee, A. van der · Hof, B. van 't · Boom, H. van der · Kobayashi, K. · Chan, L. · Havekes, L.M. · Hofker, M.H.
Keywords: Health · ApoE variants · Atherosclerosis · Gene therapy · VLDL receptor · Adenoviridae · Animals · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Cholesterol · Female · Gene Transfer Techniques · Humans · Hypercholesterolemia · Mice · Mice, Knockout · Mice, Transgenic · Receptors, LDL · Triglycerides
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 102 found. Next | Sort by date