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Showing 1 to 5 of 5 found. | Sort by date

1 A mode-of-action ontology model for safety evaluation of chemicals: Outcome of a series of workshops on repeated dose toxicity
article 2019    
Author: Desprez, B. · Birk, B. · Blaauboer, B. · Boobis, A. · Carmichael, P. · Cronin, M.T.D. · Curie, R. · Daston, G. · Hubesch, B. · Jennings, P. · Klaric, M. · Kroese, D. · Mahony, C. · Ouédraogo, G. · Piersma, A. · Richarz, A.N. · Schwarz, M. · Benthem, J. van · Water, B. van de · Vinken, M.
Keywords: Adverse outcome pathway · Mode-of-action · Ontology model · Repeated dose toxicity · Cosmetic · Adverse outcome · Biotransformation · Chemical parameters · Chemical structure · Cytotoxicity · Exposure · Human · Kinetics · Metabolism · Mode of action · Nonhuman · Note · Ontology · Organ distribution · Physical chemistry · Repeated dose toxicity · Safety · Toxicity testing · Toxicology · Workflow
[Abstract]

2 Changing the field of carcinogenicity testing of human pharmaceuticals by emphasizing mode of action
article 2017    
Author: Laan, J.W. van der · Duijndam, B. · Hoorn, T. van den · Woutersen, R. · Water, B. van de
Keywords: Nutrition · Carcinogenicity testing · Genomic approaches · Mode of action · Nuclear Receptors · Pharmaceuticals · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

3 Chemogenomics approaches for receptor deorphanization and extensions of the chemogenomics concept to phenotypic space
article 2011    
Author: Horst, E. van der · Peironcely, J.E. · Westen, G.J.P. van · Hoven, O.O. van den · Galloway, W.R.J.D. · Spring, D.R. · Wegner, J.K. · Vlijmen, H.W.T. van · Ijzerman, A.P. · Overington, J.P. · Bender, A.
Keywords: Nutrition · Chemogenomics · Deorphanization · G-protein coupled receptors · GPCR · Mode of action analysis · Orphan receptors · Proteochemometrics · Target prediction · Virtual screening · G protein coupled receptor · ligand · Bayes theorem · chemical genetics · chemistry · chemogenomic · drug activity · drug industry · genomics · phenotype · proteochemometrics · review · Healthy for Life · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

4 Effect of oral contraceptives on haemostasis variables
article 1997    
Author: Kluft, C. · Lansink, M.
Keywords: Biology · Biology · Blood Coagulation Effects · Blood Proteins · Cardiovascular Effects · Contraception · Contraceptive Agents · Contraceptive Agents, Female · Contraceptive Agents, Progestin · Contraceptive Methods · Contraceptive Mode Of Action · Developed Countries · Diseases · Europe · Family Planning · Heart Diseases · Hematological Effects · Hemic System · Literature Review · Netherlands · Oral Contraceptives · Oral Contraceptives, Combined · Oral Contraceptives, Low-dose · Physiology · Vascular Diseases · Western Europe · Biological Markers · Blood Coagulation · Contraceptives, Oral, Combined · Dose-Response Relationship, Drug · Ethinyl Estradiol · Fibrinolysis · Hemostasis · Humans · Progestins
[Abstract]

5 Lack of interaction between orlistat and oral contraceptives
article 1996    
Author: Hartmann, D. · Güzelhan, C. · Zuiderwijk, P.B.M. · Odink, J.
Keywords: Nutrition · Biology · Contraception · Contraceptive Methods--pharmacodynamics · Contraceptive Mode Of Action · Developed Countries · Double-blind Studies · Drug Interactions · Drugs · Enzyme Inhibitors--pharmacodynamics · Enzymes And Enzyme Inhibitors · Europe · Family Planning · Netherlands · Oral Contraceptives, Combined--pharmacodynamics · Oral Contraceptives--pharmacodynamics · Ovulation Suppression · Physiology · Research Methodology · Research Report · Studies · Treatment · Western Europe · Adult · Analysis of Variance · Contraceptives, Oral, Combined · Drug Interactions · Enzyme Inhibitors · Female · Humans · Lactones · Luteinizing Hormone · Progesterone · Radioimmunoassay
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 5 of 5 found. | Sort by date