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1 Toxicokinetics of the nerve agent (±)-VX in anesthetized and atropinized hairless guinea pigs and marmosets after intravenous and percutaneous administration
article 2003    
Author: Schans, M.J. van der · Lander, B.J. · Wiel, H. van der · Langenberg, J.P. · Benschop, H.P.
Keywords: Biology · Chiral HPLC · Hairless guinea pigs · Intravenous · Marmosets · Percutaneous · Persistence · Stereospecificity · Toxicokinetics · Treatment · Carbamic acid · Oxime · Volatile agent · Anesthesia · Animal experiment · Animal model · Bioavailability · Blood level · Dose response · Enantiomer · Guinea pig · Intoxication · Marmoset · Nonhuman · Primate · Toxicokinetics · Administration, Topical · Anesthesia · Animals · Atropine · Callithrix · Chemical Warfare Agents · Chromatography, Gas · Chromatography, High Pressure Liquid · Electrochemistry · Injections, Intravenous · Kinetics · Lethal Dose 50 · Male · Muscarinic Antagonists · Organothiophosphorus Compounds · Stereoisomerism · Animalia · Cavia · Cavia porcellus · Primates · Sus scrofa · Acetylcholinesterase, 9000-81-1 · Carbamic acid, 463-77-4 · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester, 50782-69-9 · Sarin, 107-44-8 · Soman, 96-64-0 · Acetylcholinesterase, EC 3.1.1.7 · Atropine, 51-55-8 · Chemical warfare agents · Muscarinic antagonists · Organothiophosphorus compounds · VX, 50782-69-9
[Abstract]

2 Beneficial effects of TCP on soman intoxication in guinea pigs : seizures, brain damage and learning behaviour
article 2001    
Author: Groot, D.M.G. de · Bierman, E.P.B. · Bruijnzeel, P.L.B. · Carpentier, P. · Kulig, B.M. · Lallement, G. · Melchers, B.P.C. · Philippens, I.H.C.H.M. · Huygevoort, A.H.B.M. van
Keywords: Toxicology · 1 (1 (2 thienyl)cyclohexyl)piperidine · 1-(1-(2-thienyl)cyclohexyl)piperidine · Atropine · Chemical warfare agent · Drug derivative · Muscarinic receptor blocking agent · N methyl dextro aspartic acid receptor · Neuroprotective agent · Chemically induced disorder · Discrimination learning · Drug effect · Pathology · Physiology · Animals · Atropine · Behavior, Animal · Brain · Chemical Warfare Agents · Cholinesterase Inhibitors · Discrimination Learning · Electroencephalography · Guinea Pigs · Male · Muscarinic Antagonists · Neuroprotective Agents · Phencyclidine · Pyridostigmine Bromide · Receptors, N-Methyl-D-Aspartate · Seizures · Soman
[Abstract]

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