Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 20 of 28 found. Next | Sort by date

1 The long-term study in rodents for identifying carcinogens: Some controversies and suggestions for improvements
article 1986    
Author: Feron, V.J. · Kroes, R.
Keywords: Animal experiment · Carcinogen testing · Chemical carcinogenesis · Intoxication · Mouse · Nonhuman · Rat · Rodent · Toxicity testing · Animal · Drug Administration Schedule · International Cooperation · Mutagenicity Tests · Rodentia · Zoology · Medicine · Geneeskunde · Pathology
[Abstract]

2 Antimutagenic activity of green tea and black tea extracts studied in a dynamic in vitro gastrointestinal model
article 2001    
Author: Krul, C.A.M. · Luiten-Schuite, A. · Tenfelde, A. · Ommen, B. van · Verhagen, H. · Havenaar, R.
Keywords: Nutrition · Animals · Antimutagenic Agents · Antioxidants · Jejunum · Models, Biological · Mutagenicity Tests · Plant Extracts · Salmonella typhimurium · Swine · Tea · Camellia sinensis · Salmonella typhimurium · Typhimurium
[Abstract]

3 Short-term tests in the framework of carcinogen risk assessment to man
article 1983    
Author: Kroes, R.
Keywords: Carcinogen · Mutagenic agent · Chemical carcinogenesis · Etiology · Human · Methodology · Netherlands · Nonhuman · Risk · Short survey · Animal · Article · Bioassay · Biological model · Drug screening · Mutagen testing · Species difference · Animal · Biological Assay · Carcinogens · Drug Evaluation, Preclinical · Models, Biological · Mutagenicity Tests · Mutagens · Risk · Species Specificity
[Abstract]

4 Germ cell mutagenesis in lambdalacZ transgenic mice treated with ethylnitrosourea : comparison with specific-locus test
article 1995    
Author: Delft, J.H.M. van · Baan, R.A.
Keywords: Biology · Animal · Comparative Study · DNA · Dose-Response Relationship, Drug · Ethylnitrosourea · Guanidine · Guanidines · Lac Operon · Male · Mice · Mice, Transgenic · Mutagenesis · Mutagenicity Tests · Spermatogenesis · Spermatozoa · Support, Non-U.S. Gov't · Time Factors
[Abstract]

5 Induction of hyperplasia in the bladder epithelium of rats by a dietary excess of acid or base: Implications for toxicity/carcinogenicity testing
article 1988    
Author: Groot, A.P. de · Feron, V.J. · Immel, H.R.
Keywords: acid · alkali · ammonium chloride · glutamate sodium · potassium bicarbonate · acid base balance · animal experiment · bladder epithelium · bladder hyperplasia · carcinogen testing · diet · male · nonhuman · rat · toxicity testing · urine ph · Acid-Base Equilibrium · Ammonium Chloride · Animal · Bladder · Carbonates · Circadian Rhythm · Diet · Epithelium · Hydrogen-Ion Concentration · Hyperplasia · Male · Mutagenicity Tests · Potassium · Rats · Urine
[Abstract]

6 Absence of an effect of lead acetate on sperm morphology, sister chromatid exchanges or on micronuclei formation in rabbits
article 1982    
Author: Willems, M.I. · Schepper, G.G.de · Wibowo, A.A.E. · Immel, H.R. · Dietrich, A.J.J. · Zielhuis, R.L.
Keywords: Broxuridine · Cadmium · Lead acetate · Zinc · Animal experiment · Blood and hemopoietic system · Bone marrow · Erythrocyte · Histology · Lymphatic system · Lymphocyte · Male genital system · Micronucleus · Microscopy · Rabbit · Sister chromatid exchange · Spermatozoon · Animal · Bone Marrow Cells · Cell Nucleus · Crossing Over (Genetics) · Erythrocytes · Female · Lead · Lymphocytes · Male · Mutagenicity Tests · Rabbits · Sister Chromatid Exchange · Sperm Count · Spermatozoa · Support, Non-U.S. Gov't
[Abstract]

7 Influence of retinoids on the mutagenicity of cigarette-smoke condensate in Salmonella typhimurium TA98
article 1986    
Author: Wilmer, J.W.G.M. · Spit, B.J.
Keywords: Cigarette smoke condensate · Retinoic acid · Retinol · Retinol acetate · Tobacco · Ames test · Chemical mutagenesis · Heredity · In vitro study · Mutagenicity · Nonhuman · Priority journal · Salmonella typhimurium · Comparative Study · Mutagenicity Tests · Mutagens · Mutation · Retinoids · Salmonella typhimurium · Smoke · Smoking · Structure-Activity Relationship · Support, Non-U.S. Gov't
[Abstract]

8 Toxicological profile for o-phenylphenol and its sodium salt
article 1998    
Author: Stouten, H.
Keywords: Toxicology · Effects · Hazard assessment · Kinetics · O-phenylphenol · Review · Sodium o-phenylphenol · Toxicity · Disinfectant agent · Hydroxybiphenyl · Phenol derivative · Cleaning · Drug toxicity · Health care personnel · Health hazard · Hospital · Human · Occupational exposure · Occupational toxicology · Risk assessment · Toxicity testing · Toxicology · Administration, Cutaneous · Administration, Oral · Animals · Biphenyl Compounds · Disinfectants · Dogs · Humans · Mice · Mutagenicity Tests · Rats · Reproduction · Skin · Tissue Distribution · Toxicity Tests
[Abstract]

9 Evaluation of the in vivo genetic toxicity of concentrated barley β-glucan
article 2004    
Author: Delaney, B. · Vogel, N. de · Krul, C.A.M.
Keywords: Health Biology · Physiological Sciences · beta glucan · corn oil · mitomycin C · analysis of variance · barley · bone marrow cell · cereal · erythrocyte · evaluation · femur · genetic toxicology · grain · hypercholesterolemia · letter · micronucleus · nonhuman · Animals · Diet · Erythrocytes · Glucans · Hordeum · Male · Mice · Micronucleus Tests · Mutagenicity Tests · Mutagens · Hordeum vulgare subsp. vulgare · Zea mays
[Abstract]

10 Prophage induction and mutagenicity of a series of anti-tumour platinum(II) and platinum(IV) co-ordination complexes
article 1982    
Author: Mattern, I.E. · Cocchiarella, L. · Kralingen, C.G. van · Lohman, P.H.M.
Keywords: Biology · Antineoplastic agent · Cisplatin · Platinum derivative · Ames test · Animal experiment · Cis platinum complex · Heredity · In vitro study · Metabolism · Mutagenicity · Prophage · Prophage induction · Salmonella · Antineoplastic Agents · Bacteriophage lambda · Histidine · Mutagenicity Tests · Mutagens · Platinum · Salmonella typhimurium · Support, Non-U.S. Gov't · Virus Activation
[Abstract]

11 The mutagenicity of isoniazid in salmonella and its effects on DNA repair and synthesis in human fibroblasts
article 1981    
Author: Wade, D.R. · Lohman, P.H.M. · Mattern, I.E. · Berends, F.
Keywords: Biology · Aroclor 1254 · Hydrazine · Isoniazid · Polychlorinated biphenyl · Radioisotope · Ames test · Animal experiment · Bacterium · DNA repair · DNA synthesis · Fibroblast · Fibroblast culture · Heredity · In vitro study · Mutagenicity · Salmonella typhimurium · Thymidine c 14 · Thymidine h 3 · Cells, Cultured · DNA · DNA Repair · Human · Hydrazines · Isoniazid · Manganese · Mutagenicity Tests · Mutagens · Salmonella typhimurium · Support, Non-U.S. Gov't
[Abstract]

12 Lack of clastogenic effects in cultured human lymphocytes treated with hydroquinone
article 2003    
Author: Roza, L. · Vogel, N. de · Delft, J.H.M. van
Keywords: Biology Health · Physiological Sciences · Antimutagen · Clastogenicity · Human lymphocytes · Hydroquinone · Mutagenicity · hydrogen peroxide · hydroquinone · hydroquinone derivative · mutagenic agent · oxidizing agent · article · concentration response · controlled study · cytotoxicity · genotoxicity · human · human cell · lymphocyte culture · male · metabolic activation · mutagenicity · normal human · structural chromosome aberration · animal · biotransformation · cell culture · chromatid · chromosome aberration · drug effect · in vitro study · liver · lymphocyte · metabolism · mutagen testing · rat · Wistar rat · Animalia · Animals · Biotransformation · Cells, Cultured · Chromatids · Chromosome Aberrations · Humans · Hydrogen Peroxide · Hydroquinones · Liver · Lymphocytes · Male · Mutagenicity Tests · Mutagens · Oxidants · Rats · Rats, Wistar
[Abstract]

13 Effect of cigarette-smoke condensate and norharman on the induction of SCEs by direct and indirect mutagens in CHO cells
article 1986    
Author: Rutten, A.A.J.J.L. · Wilmer, J.W.G.M.
Keywords: Nutrition · 2 Aminoanthracene · 2 Fluorenylamine · Benzo[a]pyrene · Beta carboline · Cyclophosphamide · Fluorenylacetohydroxamic acid · Methylnitronitrosoguanidine · Mitomycin c · N (2 fluorenyl)acetamide · Tobacco smoke · Animal cell · Cell culture · Chemical mutagenesis · Cho cell · Cigarette smoking · Drug efficacy · Drug interaction · Female genital system · Heredity · In vitro study · Methodology · Mutagen testing · Nonhuman · Priority journal · Sister chromatid exchange · Synergism · Topical drug administration · Alkaloids · Animal · Cell Line · Drug Synergism · Hamsters · Harmine · Mutagenicity Tests · Mutagens · Plants, Toxic · Sister Chromatid Exchange · Smoke · Support, Non-U.S. Gov't · Tobacco · Biology · cytology · celleer

14 Gene-mutation assays in lambda-lacZ transgenic mice : comparison of lacZ with endogenous genes in splenocytes and small intestinal epithelium
article 1998    
Author: Delft, J.H.M. van · Bergmans, A. · Dam, F.J. van · Tates, A.D. · Howard, L. · Winton, D.J. · Baan, R.A.
Keywords: Biology · λlacZ · Dlb-1 · hprt · Mutagenesis · Transgenic mouse · ethylnitrosourea · hypoxanthine phosphoribosyltransferase · mesylic acid ethyl ester · methylnitrosourea · mutagenic agent · animal cell · animal experiment · animal tissue · article · controlled study · gene · gene mutation · intestine epithelium · mouse · mutagenesis · mutagenicity · nonhuman · priority journal · small intestine mucosa · spleen cell · transgenic mouse · Alkylating Agents · Animals · Ethyl Methanesulfonate · Ethylnitrosourea · Genetic Markers · Hypoxanthine Phosphoribosyltransferase · Intestinal Mucosa · Intestine, Small · Lac Operon · Methylnitrosourea · Mice · Mice, Inbred C57BL · Mice, Transgenic · Mutagenicity Tests · Mutagens · Mutation · Spleen · Animalia · Mus musculus
[Abstract]

15 Safety evaluation of an α-cyclodextrin glycosyltranferase preparation
article 2004    
Author: Bär, A. · Krul, C.A.M. · Jonker, D. · Vogel, N. de
Keywords: Biology · Toxicology and Applied Pharmacology · alpha cyclodextrin glycosyltransferase · amylase · unclassified drug · Ames test · animal experiment · animal model · animal tissue · article · aspiration · bacterial strain · batch fermentation · chromosome aberration · controlled study · Escherichia coli · evaluation · female · food safety · foraging · gastroesophageal reflux · genetic recombination · genotoxicity · Klebsiella oxytoca · lymphocyte culture · male · nonhuman · priority journal · rat · respiratory tract disease · toxicity testing · Animals · Chromosome Aberrations · Escherichia coli · Female · Food Additives · Glucosyltransferases · Humans · Klebsiella · Lymphocytes · Male · Mutagenicity Tests · Rats · Rats, Wistar · Toxicity Tests · Toxicity Tests, Chronic · Escherichia coli · Klebsiella oxytoca
[Abstract]

16 Application of a dynamic in vitro gastrointestinal tract model to study the availability of food mutagens, using heterocyclic aromatic amines as model compounds
article 2000    
Author: Krul, C.A.M. · Luiten-Schuite, A. · Baan, R. · Verhagen, H. · Mohn, G. · Feron, V. · Havenaar, R.
Keywords: Biology · Medicine · Geneeskunde · Health · Gezondheid · Dietetics · Voedingsleer · Availability · Dynamic in vitro gastrointestinal model · Heterocyclic aromatic amines · Meat mutagens · Transit time · Aromatic amine · Heterocyclic amine · Mutagenic agent · Animal experiment · Animal tissue · Bile secretion · Bioavailability · Computer model · Controlled study · Digestion · Gastrointestinal tract function · In vitro study · Intestine absorption · Intestine transit time · Male · Nonhuman · Pancreas secretion · Peristalsis · PH · Rat · Salmonella typhimurium · Stomach secretion · Temperature · Validation process · Biological Availability · Chromatography, High Pressure Liquid · Digestive System · Heterocyclic Compounds · Models, Biological · Mutagenicity Tests · Mutagens · Animalia · Mammalia · Salmonella typhimurium · Typhimurium
[Abstract]

17 Toxicological profile for o-benzyl-p-chlorophenol
article 1998    
Author: Stouten, H. · Bessems, J.G.M.
Keywords: Nutrition · Effects · Hazard assessment · Kinetics · o-benzo-p-chlorophenol · Review · Toxicity · chlorophenol · disinfectant agent · phenol derivative · animal experiment · animal model · carcinogenicity · cleaning · controlled study · health hazard · hospital · human · male · occupational exposure · occupational toxicology · priority journal · rat · review · toxicity · toxicology · xenobiotic metabolism · Administration, Oral · Adult · Animals · Dichlorophen · Disinfectants · Female · Housekeeping, Hospital · Humans · Male · Middle Aged · Mutagenicity Tests · Occupational Exposure · Personnel, Hospital · Rabbits · Rats · Reproduction · Skin · Tissue Distribution
[Abstract]

18 Comparison of immunoaffinity chromatography enrichment and nuclease P1 procedures for 32P-postlabelling analysis of PAH- DNA adducts
article 1998    
Author: Randerath, K. · Sriram, P. · Moorthy, B. · Aston, J.P. · Baan, R.A. · Berg, P.T.M. van den · Booth, E.D. · Watson, W.P.
Keywords: Nutrition · 32P-postlabelling · DNA adducts · Immunoaffinity · Nuclease P1 · PAH · Nuclease · Phosphorus 32 · Polycyclic aromatic hydrocarbon · Adsorption · Animal cell · Column chromatography · Contamination · Dna adduct · Enzyme analysis · Enzyme specificity · Genotoxicity · Immunoaffinity chromatography · Mutagenicity · Nonhuman · Protein modification · 9,10-Dimethyl-1,2-benzanthracene · Animals · Antibodies, Monoclonal · Aspergillus Nuclease S1 · Benzo(a)pyrene · Carcinogens · Chromatography, Affinity · Chrysenes · DNA Adducts · Fluorescent Antibody Technique · Isotope Labeling · Mice · Mutagenicity Tests · Mutagens · Phosphorus Radioisotopes · Polycyclic Hydrocarbons, Aromatic · Skin · Animalia
[Abstract]

19 Safety evaluation of β-glucanase derived from Trichoderma reesei: Summary of toxicological data
article 1995    
Author: Coenen, T.M.M. · Schoenmakers, A.C.M. · Verhagen, H.
Keywords: Toxicology · barlican · beta glucan hydrolase · unclassified drug · animal experiment · article · chicken · chronic toxicity · controlled study · eye irritation · female · guinea pig · male · mutagenicity · nonhuman · rabbit · rat · skin irritation · skin sensitization · Administration, Oral · Animal · Animal Feed · beta-Glucosidase · Biological Products · Chickens · CHO Cells · Dermatitis, Contact · Environmental Exposure · Female · Food Additives · Guinea Pigs · Hamsters · Lethal Dose 50 · Male · Mutagenicity Tests · No-Observed-Adverse-Effect Level · Rabbits · Rats · Rats, Wistar · Salmonella typhimurium · Toxicity Tests · Trichoderma · Animalia · Cavia porcellus · Gallus gallus · Hypocrea jecorina · Oryctolagus cuniculus · Sus scrofa · Trichoderma
[Abstract]

20 Hazard assessment of nitrosamine and nitramine by-products of amine-based CCS: Alternative approaches
article 2015    
Author: Buist, H.E. · Devito, S. · Goldbohm, R.A. · Stierum, R.H. · Venhorst, J. · Kroese, E.D.
Keywords: Nutrition · Carbon capture and storage · Carcinogenicity · Cell transformation assay · Mutagenicity · Nitramines · Nitrosamines · Predictive in vitro models · Predictive in vivo models · QSARs · Transgenic animal test · Aniline derivative · Nitrobenzene derivative · Animal · Biological model · Carbon sequestration · Carcinogen testing · Cell transformation · Chemical structure · Chemically induced · Chemistry · LD50 · Mutagen testing · Neoplasm · Procedures · Quantitative structure activity relation · Risk assessment · Transgenic mouse · Aniline Compounds · Animals · Carbon Sequestration · Carcinogenicity Tests · Cell Transformation, Neoplastic · Lethal Dose 50 · Mice, Transgenic · Models, Biological · Molecular Structure · Mutagenicity Tests · Neoplasms · Nitrobenzenes · Quantitative Structure-Activity Relationship · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 28 found. Next | Sort by date