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1 Mutagenicity of antitumour platinum compounds
article 1980    
Author: Cocchiarella, L. · Mattern, I.E. · Kralingen, C.G. van
Keywords: Biology · Oroclor · Platinum derivative · Polychlorinated biphenyl · Unclassified drug · Abstract report · Ames test · Heredity · Mutagenicity

2 Lack of clastogenic effects in cultured human lymphocytes treated with hydroquinone
article 2003    
Author: Roza, L. · Vogel, N. de · Delft, J.H.M. van
Keywords: Biology Health · Physiological Sciences · Antimutagen · Clastogenicity · Human lymphocytes · Hydroquinone · Mutagenicity · hydrogen peroxide · hydroquinone · hydroquinone derivative · mutagenic agent · oxidizing agent · article · concentration response · controlled study · cytotoxicity · genotoxicity · human · human cell · lymphocyte culture · male · metabolic activation · mutagenicity · normal human · structural chromosome aberration · animal · biotransformation · cell culture · chromatid · chromosome aberration · drug effect · in vitro study · liver · lymphocyte · metabolism · mutagen testing · rat · Wistar rat · Animalia · Animals · Biotransformation · Cells, Cultured · Chromatids · Chromosome Aberrations · Humans · Hydrogen Peroxide · Hydroquinones · Liver · Lymphocytes · Male · Mutagenicity Tests · Mutagens · Oxidants · Rats · Rats, Wistar
[Abstract]

3 Antimutagenic activity of green tea and black tea extracts studied in a dynamic in vitro gastrointestinal model
article 2001    
Author: Krul, C.A.M. · Luiten-Schuite, A. · Tenfelde, A. · Ommen, B. van · Verhagen, H. · Havenaar, R.
Keywords: Nutrition · Animals · Antimutagenic Agents · Antioxidants · Jejunum · Models, Biological · Mutagenicity Tests · Plant Extracts · Salmonella typhimurium · Swine · Tea · Camellia sinensis · Salmonella typhimurium · Typhimurium
[Abstract]

4 Toxicological characterization of diesel engine emissions using biodiesel and a closed soot filter
article 2011    
Author: Kooter, I.M. · Vugt, M.A.T.M. van · Jedynska, A.D. · Tromp, P.C. · Houtzager, M.M.G. · Verbeek, R.P. · Kadijk, G. · Mulderij, M. · Krul, C.A.M.
Keywords: Environment · Biodiesel · Diesel particulates filter · Engine emission · Mutagenicity · Oxidative stress · Earth & Environment Life · AEC - Applied Environmental Chemistry QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

5 Health effects of soy-biodiesel emissions: mutagenicity-emission factors.
article 2015    
Author: Mutlu, E. · Warren, S.H. · Matthews, P.P · King, C. · Walsh, L. · Kligerman, A.D · Schmid, J.E · Janek, D. · Kooter, I.M. · Linak, W.P · Gilmour, M.I · DeMarini, D.M.
Keywords: Health · Combustion emissions · complex mixtures · mutagenicity · Urban Development · Built Environment · Urban Mobility & Environment · AEC - Applied Environmental Chemistry · ELSS - Earth, Life and Social Sciences
[Abstract]

6 The long-term study in rodents for identifying carcinogens: Some controversies and suggestions for improvements
article 1986    
Author: Feron, V.J. · Kroes, R.
Keywords: Animal experiment · Carcinogen testing · Chemical carcinogenesis · Intoxication · Mouse · Nonhuman · Rat · Rodent · Toxicity testing · Animal · Drug Administration Schedule · International Cooperation · Mutagenicity Tests · Rodentia · Zoology · Medicine · Geneeskunde · Pathology
[Abstract]

7 Prophage induction and mutagenicity of a series of anti-tumour platinum(II) and platinum(IV) co-ordination complexes
article 1982    
Author: Mattern, I.E. · Cocchiarella, L. · Kralingen, C.G. van · Lohman, P.H.M.
Keywords: Biology · Antineoplastic agent · Cisplatin · Platinum derivative · Ames test · Animal experiment · Cis platinum complex · Heredity · In vitro study · Metabolism · Mutagenicity · Prophage · Prophage induction · Salmonella · Antineoplastic Agents · Bacteriophage lambda · Histidine · Mutagenicity Tests · Mutagens · Platinum · Salmonella typhimurium · Support, Non-U.S. Gov't · Virus Activation
[Abstract]

8 The mutagenicity of isoniazid in salmonella and its effects on DNA repair and synthesis in human fibroblasts
article 1981    
Author: Wade, D.R. · Lohman, P.H.M. · Mattern, I.E. · Berends, F.
Keywords: Biology · Aroclor 1254 · Hydrazine · Isoniazid · Polychlorinated biphenyl · Radioisotope · Ames test · Animal experiment · Bacterium · DNA repair · DNA synthesis · Fibroblast · Fibroblast culture · Heredity · In vitro study · Mutagenicity · Salmonella typhimurium · Thymidine c 14 · Thymidine h 3 · Cells, Cultured · DNA · DNA Repair · Human · Hydrazines · Isoniazid · Manganese · Mutagenicity Tests · Mutagens · Salmonella typhimurium · Support, Non-U.S. Gov't
[Abstract]

9 Influence of retinoids on the mutagenicity of cigarette-smoke condensate in Salmonella typhimurium TA98
article 1986    
Author: Wilmer, J.W.G.M. · Spit, B.J.
Keywords: Cigarette smoke condensate · Retinoic acid · Retinol · Retinol acetate · Tobacco · Ames test · Chemical mutagenesis · Heredity · In vitro study · Mutagenicity · Nonhuman · Priority journal · Salmonella typhimurium · Comparative Study · Mutagenicity Tests · Mutagens · Mutation · Retinoids · Salmonella typhimurium · Smoke · Smoking · Structure-Activity Relationship · Support, Non-U.S. Gov't
[Abstract]

10 Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons
article 2000    
Author: Kappers, W.A. · Och, F.M.M. van · Groene, E.M. de · Horbach, G.J.
Keywords: Nutrition · Acetyltransferase · Amestest · AminoPAHs · Cytochrome P450 · HPRT · Mutagenicity · NIH/3T3 cells · NitroPAHs · Shuttle vector · V79 cells · Cytochrome P450 · Polycyclic aromatic hydrocarbon · Animal cell · Cell strain 3T3 · Controlled study · Enzyme activity · Gene locus · In vitro study · Mouse · Mutagenicity · Nonhuman · Priority journal · Reaction analysis · Reporter gene · Shuttle vector · 3T3 Cells · Animals · Cell Line · Cell Survival · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Enzyme Inhibitors · Ethyl Methanesulfonate · Fluorenes · Humans · Hypoxanthine Phosphoribosyltransferase · Ketoconazole · Lac Operon · Mice · Microsomes, Liver · Mutagenicity Tests · Mutagens · Mutation · Polycyclic Hydrocarbons, Aromatic · Pyrenes · Rats · Recombinant Fusion Proteins · Salmonella typhimurium · Theophylline · Animalia · Cricetinae · Cricetulus griseus · Eukaryota · Salmonella typhimurium · Typhimurium
[Abstract]

11 Germ cell mutagenesis in lambdalacZ transgenic mice treated with ethylnitrosourea : comparison with specific-locus test
article 1995    
Author: Delft, J.H.M. van · Baan, R.A.
Keywords: Biology · Animal · Comparative Study · DNA · Dose-Response Relationship, Drug · Ethylnitrosourea · Guanidine · Guanidines · Lac Operon · Male · Mice · Mice, Transgenic · Mutagenesis · Mutagenicity Tests · Spermatogenesis · Spermatozoa · Support, Non-U.S. Gov't · Time Factors
[Abstract]

12 Use of Umbra pygmaea and Mytilus edulis to detect mutagens in the aquatic environment
article 1981    
Author: Vink, G.J. · Davis, P.B. · Hooftman, R.N. · Mattern, I.E.
Keywords: Biology · Aroclor · Benzo[a]pyrene · Mesylic acid ethyl ester · Mesylic acid methyl ester · Polychlorinated biphenyl · Triaziquone · Abstract report · Animal experiment · Chromosome aberration · Fin · Fish · Gill · Heredity · Mutagenicity · Water pollution
[Abstract]

13 The mutagenicity of isoniazid in salmonella and its effects on DNA repair and synthesis in human fibroblasts
article 1980    
Author: Wade, D.R. · Lohman, P.H.M.
Keywords: Biology · Hydrazine · Isoniazid · Manganese · Abstract report · Adverse drug reaction · Cell culture · Chemical mutagenesis · DNA repair · DNA synthesis · Fibroblast · Human · Human cell · In vitro study · Liver microsome · Mouse · Mutagenicity · Normal human · Pharmacokinetics · Rat · Salmonella · Salmonella typhimurium · Soft tissue
[Abstract]

14 Short-term tests in the framework of carcinogen risk assessment to man
article 1983    
Author: Kroes, R.
Keywords: Carcinogen · Mutagenic agent · Chemical carcinogenesis · Etiology · Human · Methodology · Netherlands · Nonhuman · Risk · Short survey · Animal · Article · Bioassay · Biological model · Drug screening · Mutagen testing · Species difference · Animal · Biological Assay · Carcinogens · Drug Evaluation, Preclinical · Models, Biological · Mutagenicity Tests · Mutagens · Risk · Species Specificity
[Abstract]

15 Gene-mutation assays in lambda-lacZ transgenic mice : comparison of lacZ with endogenous genes in splenocytes and small intestinal epithelium
article 1998    
Author: Delft, J.H.M. van · Bergmans, A. · Dam, F.J. van · Tates, A.D. · Howard, L. · Winton, D.J. · Baan, R.A.
Keywords: Biology · λlacZ · Dlb-1 · hprt · Mutagenesis · Transgenic mouse · ethylnitrosourea · hypoxanthine phosphoribosyltransferase · mesylic acid ethyl ester · methylnitrosourea · mutagenic agent · animal cell · animal experiment · animal tissue · article · controlled study · gene · gene mutation · intestine epithelium · mouse · mutagenesis · mutagenicity · nonhuman · priority journal · small intestine mucosa · spleen cell · transgenic mouse · Alkylating Agents · Animals · Ethyl Methanesulfonate · Ethylnitrosourea · Genetic Markers · Hypoxanthine Phosphoribosyltransferase · Intestinal Mucosa · Intestine, Small · Lac Operon · Methylnitrosourea · Mice · Mice, Inbred C57BL · Mice, Transgenic · Mutagenicity Tests · Mutagens · Mutation · Spleen · Animalia · Mus musculus
[Abstract]

16 Safety evaluation of β-glucanase derived from Trichoderma reesei: Summary of toxicological data
article 1995    
Author: Coenen, T.M.M. · Schoenmakers, A.C.M. · Verhagen, H.
Keywords: Toxicology · barlican · beta glucan hydrolase · unclassified drug · animal experiment · article · chicken · chronic toxicity · controlled study · eye irritation · female · guinea pig · male · mutagenicity · nonhuman · rabbit · rat · skin irritation · skin sensitization · Administration, Oral · Animal · Animal Feed · beta-Glucosidase · Biological Products · Chickens · CHO Cells · Dermatitis, Contact · Environmental Exposure · Female · Food Additives · Guinea Pigs · Hamsters · Lethal Dose 50 · Male · Mutagenicity Tests · No-Observed-Adverse-Effect Level · Rabbits · Rats · Rats, Wistar · Salmonella typhimurium · Toxicity Tests · Trichoderma · Animalia · Cavia porcellus · Gallus gallus · Hypocrea jecorina · Oryctolagus cuniculus · Sus scrofa · Trichoderma
[Abstract]

17 Comparison of immunoaffinity chromatography enrichment and nuclease P1 procedures for 32P-postlabelling analysis of PAH- DNA adducts
article 1998    
Author: Randerath, K. · Sriram, P. · Moorthy, B. · Aston, J.P. · Baan, R.A. · Berg, P.T.M. van den · Booth, E.D. · Watson, W.P.
Keywords: Nutrition · 32P-postlabelling · DNA adducts · Immunoaffinity · Nuclease P1 · PAH · Nuclease · Phosphorus 32 · Polycyclic aromatic hydrocarbon · Adsorption · Animal cell · Column chromatography · Contamination · Dna adduct · Enzyme analysis · Enzyme specificity · Genotoxicity · Immunoaffinity chromatography · Mutagenicity · Nonhuman · Protein modification · 9,10-Dimethyl-1,2-benzanthracene · Animals · Antibodies, Monoclonal · Aspergillus Nuclease S1 · Benzo(a)pyrene · Carcinogens · Chromatography, Affinity · Chrysenes · DNA Adducts · Fluorescent Antibody Technique · Isotope Labeling · Mice · Mutagenicity Tests · Mutagens · Phosphorus Radioisotopes · Polycyclic Hydrocarbons, Aromatic · Skin · Animalia
[Abstract]

18 Genetic and reproductive toxicity of butadiene and isoprene
article 2001    
Author: Anderson, D.
Keywords: Nutrition · Cytogenetic effects · Isoprene · Somatic and germ cells · 1,2 epoxy 3 butene · 1,3 butadiene · butadiene diepoxide · cytochrome P450 · hypoxanthine phosphoribosyltransferase · alkalinity · biological monitoring · carcinogenesis · CHO cell · chromosome aberration · comparative study · concentration response · conference paper · cytogenetics · Drosophila melanogaster · exposure · gene translocation · genotoxicity · lethal mutant · liver metabolism · mutagenicity · nonhuman · reproductive toxicity · Salmonella typhimurium · Testis · Animalia · Drosophila melanogaster · Melanogaster · Salmonella typhimurium · Typhimurium · Cytogenetic effects · Isoprene · Somatic and germ cells · 1,2 epoxy 3 butene · 1,3 butadiene · butadiene diepoxide · cytochrome P450 · hypoxanthine phosphoribosyltransferase · alkalinity · biological monitoring · carcinogenesis · CHO cell · chromosome aberration · comparative study · concentration response · conference paper · cytogenetics · Drosophila melanogaster · exposure · gene translocation · genotoxicity · lethal mutant · liver metabolism · mutagenicity · nonhuman · reproductive toxicity · Salmonella typhimurium · sister chromatid exchange · spermatozoon motility · tissue distribution · Animals · Butadienes · Female · Hemiterpenes · Humans · Male · Mice · Mutagenicity Tests · Mutagens · Occupational Exposure · Ovary · Pentanes · Pregnancy · Rats · Reproduction · Testis · Animalia · Drosophila melanogaster · Melanogaster · Salmonella typhimurium · Typhimurium
[Abstract]

19 Hazard assessment of nitrosamine and nitramine by-products of amine-based CCS: Alternative approaches
article 2015    
Author: Buist, H.E. · Devito, S. · Goldbohm, R.A. · Stierum, R.H. · Venhorst, J. · Kroese, E.D.
Keywords: Nutrition · Carbon capture and storage · Carcinogenicity · Cell transformation assay · Mutagenicity · Nitramines · Nitrosamines · Predictive in vitro models · Predictive in vivo models · QSARs · Transgenic animal test · Aniline derivative · Nitrobenzene derivative · Animal · Biological model · Carbon sequestration · Carcinogen testing · Cell transformation · Chemical structure · Chemically induced · Chemistry · LD50 · Mutagen testing · Neoplasm · Procedures · Quantitative structure activity relation · Risk assessment · Transgenic mouse · Aniline Compounds · Animals · Carbon Sequestration · Carcinogenicity Tests · Cell Transformation, Neoplastic · Lethal Dose 50 · Mice, Transgenic · Models, Biological · Molecular Structure · Mutagenicity Tests · Neoplasms · Nitrobenzenes · Quantitative Structure-Activity Relationship · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

20 Formation and persistence of O6-ethylguanine in genomic and transgene DNA in liver and brain of λlacZ transgenic mice treated with N-ethyl-N-nitrosourea
article 1996    
Author: Mientjes, E.J. · Hochleitner, K. · Luiten-Schuite, A. · Delft, J.H.M. van · Thomale, J. · Berends, F. · Rajewsky, M.F. · Lohman, P.H.M. · Baan, R.A.
Keywords: Toxicology · 6 o alkylguanine dna alkyltransferase · dna · ethylnitrosourea · guanine derivative · 6 ethylguanine · 6-ethylguanine · 7 ethylguanine · 7-ethylguanine · DNA · drug derivative · guanine · mutagenic agent · animal experiment · animal tissue · article · brain · controlled study · dna adduct · dna repair · enzyme inhibition · female · immunoblotting · liver · mouse · mutagenicity · nonhuman · priority journal · transgene · transgenic mouse · animal · bacteriophage lambda · biosynthesis · DNA repair · drug effect · genetics · genome · lactose operon · metabolism · mutagen testing · physiology · polymerase chain reaction · sensitivity and specificity · Animals · Bacteriophage lambda · Brain · DNA · DNA Repair · Ethylnitrosourea · Female · Genome · Guanine · Immunoblotting · Lac Operon · Liver · Mice · Mice, Transgenic · Mutagenicity Tests · Mutagens · Polymerase Chain Reaction · Sensitivity and Specificity
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 39 found. Next | Sort by date