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1 Exposure and risk estimation for pesticides in high-volume spraying
article 1998    
Author: Vreede, J.A.F. de · Brouwer, D.H. · Stevenson, H. · Hemmen, J.J. van
Keywords: Health risks · Risk assessment · Skin · Spraying · Indicative limit value (ILV) · No observed adverse effect level (NOAEL) · Occupational risks · Methomyl · Aerosol · Chrysanthemum · Health hazard · Human · Inhalation · Netherlands · protective clothing · Agriculture · Humans · No-Observed-Adverse-Effect Level · Occupational Exposure · Pesticides
[Abstract]

2 Hazard characterisation of chemicals in food and diet : dose response, mechanisms and extrapolation issues
article 2002    
Author: Dybing, E. · Doe, J. · Groten, J. · Kleiner, J. · O'Brien, J. · Renwick, A.G. · Schlatter, J. · Steinberg, P. · Tritscher, A. · Walker, R. · Younes, M.
Keywords: Nutrition · Animals · Dose-Response Relationship, Drug · European Union · Hazardous Substances · Humans · Micronutrients · Models, Animal · Molecular Weight · No-Observed-Adverse-Effect Level · Risk Assessment · Rodentia · Species Specificity · Animalia · Rodentia
[Abstract]

3 Is current risk assessment of non-genotoxic carcinogens protective?
article 2018    
Author: Braakhuis, H.M. · Slob, W. · Olthof, E.D. · Wolterink, G. · Zwart, E.P. · Gremmer, E.R. · Rorije, E. · Benthem, J. van · Woutersen, R. · Laan, J.W. van der · Luijten, M.
Keywords: Health · Benchmark dose approach · Carcinogenicity · Chemicals · No-Observed-Adverse-Effect-Level · Non-genotoxic carcinogens · Repeated dose toxicity · Risk assessment · Subchronic toxicity
[Abstract]

4 A simple method for quantitative risk assessment of non-threshold carcinogens based on the dose descriptor T25
article 2001    
Author: Sanner, T. · Dybing, E. · Willems, M.I. · Kroese, E.D.
Keywords: Nutrition · Animals · Carcinogens · Disease Models, Animal · Dose-Response Relationship, Drug · Female · Glioma · Humans · Lymphoma · Male · Mice · Models, Biological · No-Observed-Adverse-Effect Level · Occupational Exposure · Rats · Risk Assessment · United States · United States Environmental Protection Agency
[Abstract]

5 The benchmark approach applied to a 28-day toxicity study with rhodorsil silane in rats : the impact of increasing the number of dose groups
article 2001    
Author: Woutersen, R.A. · Jonker, D. · Stevenson, H. · Biesebeek, J.D. te · Slob, W.
Keywords: Nutrition · Alanine Transaminase · Animals · Aspartate Aminotransferases · Dose-Response Relationship, Drug · Erythrocyte Count · Female · Hematopoiesis · Hemoglobins · Liver · No-Observed-Adverse-Effect Level · Organ Size · Rats · Rats, Wistar · Research Design · Silanes · Silicates · Spleen · Toxicity Tests · Animalia · Zea mays
[Abstract]

6 Assessment factors for human health risk assessment: A discussion paper
article 1999    
Author: Vermeire, T. · Stevenson, H. · Pieters, M.N. · Rennen, M. · Slob, W. · Hakkert, B.C.
Keywords: Nutrition · Data base · Dose response · Health hazard · Human · Motivation · Probability · Risk assessment · Standard · Animals · Benchmarking · Dose-Response Relationship, Drug · Health · Humans · No-Observed-Adverse-Effect Level · Probability · Risk Assessment · Risk Factors · Toxicity Tests
[Abstract]

7 Evaluation of potential neurotoxic effects of occupational exposure to (L)-Lactates
article 2001    
Author: Clary, J.J. · Feron, V.J. · Velthuijsen, J.A. van
Keywords: Toxicology · Chronic neurotoxicity · Chronic toxic encephalopathy · Lactate esters · Organo psycho syndrome · Solvents · 2 ethylhexanol · 2 propanol · alcohol · butanol · isobutanol · lactic acid derivative · methanol · propanol · animal experiment · article · brain disease · disease association · hydrolysis · mouse · neurotoxicity · nonhuman · occupational exposure · priority journal · rat · risk assessment · toxicity testing · Alcohols · Animals · Esters · Humans · Hydrolysis · Lactates · Neurotoxicity Syndromes · No-Observed-Adverse-Effect Level · Occupational Exposure · Solvents · Toxicity Tests · Volatilization
[Abstract]

8 Setting an indoor air exposure limit for formaldehyde: Factors of concern
article 2008    
Author: Arts, J.H.E. · Muijser, H. · Kuper, C.F. · Woutersen, R.A.
Keywords: Health · Toxicology and Applied Pharmacology · Exposure limit · Formaldehyde · Indoor air · Sensory irritation · Air quality standard · Ambient air · Environmental exposure · Eye irritation · Nose irritation · Throat irritation · Administration, Inhalation · Air Pollutants · Carcinogens · Child · European Union · Eye · Formaldehyde · Humans · Inhalation Exposure · Irritants · No-Observed-Adverse-Effect Level · Nose · Occupational Exposure · Pharynx · Trigeminal Nerve
[Abstract]

9 Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients
article 2007    
Author: Kroes, R. · Renwick, A.G. · Feron, V. · Galli, C.L. · Gibney, M. · Greim, H. · Guy, R.H. · Lhuguenot, J.C. · Sandt, J.J.M. van de
Keywords: Chemistry Safety · Analytical research · Cosmetic ingredients · Risk assessment · Threshold of toxicological concern (TTC) · Trans-dermal absorption · cosmetic · flavoring agent · article · chemical structure · comparative study · drug exposure · first pass effect · food · human · nonhuman · physical chemistry · risk assessment · Administration, Cutaneous · Administration, Oral · Cosmetics · Decision Support Techniques · Decision Trees · Humans · No-Observed-Adverse-Effect Level · Safety · Toxicity Tests
[Abstract]

10 Subchronic (13-week) oral toxicity study of α-cyclodextrin in dogs
article 2004    
Author: Lina, B.A.R. · Bär, A.
Keywords: Biology Toxicology · Toxicology and Applied Pharmacology · alpha cyclodextrin · animal experiment · animal model · animal tissue · article · cecum · colon · controlled study · diarrhea · dietary intake · dog · female · food intake · histopathology · intestine · male · mortality · nonhuman · ophthalmoscopy · priority journal · statistical significance · urine · urine pH · Administration, Oral · alpha-Cyclodextrins · Animals · Cyclodextrins · Diarrhea · Dogs · Female · Male · No-Observed-Adverse-Effect Level · Organ Size · Toxicity Tests, Chronic · Canis familiaris
[Abstract]

11 Inhaled formaldehyde: Evaluation of sensory irritation in relation to carcinogenicity
article 2006    
Author: Arts, J.H.E. · Rennen, M.A.J. · Heer, C.de
Keywords: Health · Toxicology and Applied Pharmacology · Benchmark dose · Carcinogenicity · Formaldehyde · Sensory irritation · formaldehyde · article · carcinogenicity · computer program · eye irritation · human · nonhuman · nose injury · nose irritation · odor · priority journal · rating scale · respiratory tract disease · sense organ · smelling · symptomatology · Administration, Inhalation · Air Pollutants · Animals · Carcinogens · Carcinoma · Eye · Formaldehyde · Humans · Inhalation Exposure · Irritants · Nasal Mucosa · No-Observed-Adverse-Effect Level · Nose Neoplasms · Occupational Exposure · Pharynx · Risk Assessment · Animalia
[Abstract]

12 Effects of vapours of chlorpropham and ethofumesate on wild plant species
article 2001    
Author: Franzaring, J. · Kempenaar, C. · Eerden, L.J.M. van
Keywords: Environment · Natural vegetation · NOEC · Non-target plants · Phytotoxicity · Risk assessment · Chlorophyll · Fluorescence · Fumigation · Vaporization · Foliar injury · Herbicides · Chlorophyll · Chlorpropham · Ethofumesate · Herbicide · Unclassified drug · Growth response · Herbicide · Injury · Vaporization · Drug toxicity · Fluorescence · Infection control · Morphology · Plant · Plant growth · Species difference · Vapor · Vegetation · Benzofurans · Chlorpropham · Environmental Pollutants · Herbicides · Mesylates · No-Observed-Adverse-Effect Level · Plant Leaves · Plants · Volatilization · Agrostemma · Agrostemma githago · Bryophyta · bryophytes · Embryophyta
[Abstract]

13 Toxicological evaluation and risk assessment of chemical mixtures
article 1998    
Author: Cassee, F.R. · Groten, J.P. · Bladeren, P.J. van · Feron, V.J.
Keywords: Nutrition · Combination toxicology · Complex mixtures · Isoboles · Physiologically based toxicokinetic modeling · Response surface analysis · Simple mixtures · Weight of evidence approach · Chemical compound · Chemical analysis · Dose response · Drug mechanism · Drug potentiation · Environmental exposure · Review · Risk assessment · Toxin analysis · Animals · Drug Interactions · Drug Synergism · Guidelines · International Cooperation · Male · Models, Biological · Models, Statistical · No-Observed-Adverse-Effect Level · Rats · Risk Assessment · Xenobiotics
[Abstract]

14 Oral-to-inhalation route extrapolation in occupational health risk assessment: A critical assessment
article 2004    
Author: Rennen, M.A.J. · Bouwman, T. · Wilschut, A. · Bessems, J.G.M. · Heer, C.de
Keywords: Health Chemistry · Food and Chemical Risk Analysis · Inhalation · Local effects · Oral · Respiratory · Risk assessment · Route extrapolation · Accuracy · Analytical error · Data base · Inhalation · Intermethod comparison · Occupational exposure · Occupational hazard · Priority journal · Quantitative analysis · Reliability · Risk assessment · Screening test · Administration, Inhalation · Administration, Oral · Animals · Dose-Response Relationship, Drug · Humans · Models, Biological · No-Observed-Adverse-Effect Level · Occupational Exposure · Pesticides · Predictive Value of Tests · Research Design · Risk Assessment · Species Specificity
[Abstract]

15 Subacute (28-day) toxicity of furfural in Fischer 344 rats: A comparison of the oral and inhalation route
article 2004    
Author: Arts, J.H.E. · Muijser, H. · Appel, M.J. · Kuper, C.F. · Bessems, J.G.M. · Woutersen, R.A.
Keywords: Biology Health · Toxicology and Applied Pharmacology · Fischer rat · Furfural · Inhalation · Oral · Route-to-route extrapolation · Subacute toxicity · corn oil · furfural · air · animal experiment · animal model · animal tissue · article · comparative study · concentration response · controlled study · exposure · female · histopathology · kidney mass · liver weight · male · mortality · nonhuman · olfactory epithelium · rat · survival · toxicity testing · Administration, Inhalation · Administration, Oral · Animals · Dose-Response Relationship, Drug · Female · Furaldehyde · Kidney · Liver · Longevity · Male · No-Observed-Adverse-Effect Level · Olfactory Mucosa · Organ Size · Rats · Rats, Inbred F344 · Zea mays
[Abstract]

16 Intake of butylated hydroxyanisole and butylated hydroxytoluene and stomach cancer risk : results from analyses in the Netherlands : cohort study
article 2000    
Author: Botterweck, A.A.M. · Verhagen, H. · Goldbohm, R.A. · Kleinjans, J. · Brandt, P.A. van den
Keywords: Nutrition · Medicine · Geneeskunde · Pharmacology · Toxicology · Pathology · Butylated hydroxyanisole · Butylated hydroxytoluene · Cohort study · Stomach neoplasms · Butylated hydroxyanisole · Butylcresol · Fat · Oil · Adult · Aged · Cancer risk · Chemical analysis · Cohort analysis · Dietary intake · Female · Food analysis · Food intake · Human · Male · Netherlands · Questionnaire · Statistical analysis · Stomach cancer · Aged · Antioxidants · Butylated Hydroxyanisole · Butylated Hydroxytoluene · Cohort Studies · Diet · Female · Food Additives · Humans · Male · Middle Aged · Netherlands · No-Observed-Adverse-Effect Level · Prospective Studies · Questionnaires · Risk Assessment · Stomach Neoplasms
[Abstract]

17 Safety evaluation of β-glucanase derived from Trichoderma reesei: Summary of toxicological data
article 1995    
Author: Coenen, T.M.M. · Schoenmakers, A.C.M. · Verhagen, H.
Keywords: Toxicology · barlican · beta glucan hydrolase · unclassified drug · animal experiment · article · chicken · chronic toxicity · controlled study · eye irritation · female · guinea pig · male · mutagenicity · nonhuman · rabbit · rat · skin irritation · skin sensitization · Administration, Oral · Animal · Animal Feed · beta-Glucosidase · Biological Products · Chickens · CHO Cells · Dermatitis, Contact · Environmental Exposure · Female · Food Additives · Guinea Pigs · Hamsters · Lethal Dose 50 · Male · Mutagenicity Tests · No-Observed-Adverse-Effect Level · Rabbits · Rats · Rats, Wistar · Salmonella typhimurium · Toxicity Tests · Trichoderma · Animalia · Cavia porcellus · Gallus gallus · Hypocrea jecorina · Oryctolagus cuniculus · Sus scrofa · Trichoderma
[Abstract]

18 The application of in vitro data in the derivation of the acceptable daily intake of food additives
article 1999    
Author: Walton, K. · Walker, R. · Sandt, J.J.M. van de · Castell, J.V. · Knapp, A.G.A.A. · Kozianowski, G. · Roberfroid, M. · Schilter, B.
Keywords: Nutrition · Acceptable daily intake · Food additives · In vitro · Metabolism · Toxicodynamics and uncertainty factor · Toxicokinetics · 2 hydroxybiphenyl · Aluminum · Aspartame · Biphenyl · Brilliant blue · Butylcresol · Curcumin · Cyclamate sodium · Cyclohexylamine · Dodecyl gallate · Erythrosine · Ferrocyanide · Food additive · Gallic acid · Gallic acid propyl ester · Nitrate · Nitrite · Tartrazine · Tiabendazole · Dietary intake · Food safety · Human · Nonhuman · Review · Risk assessment · Species difference · Toxicity testing · Toxicokinetics · Animals · Food Additives · Humans · No-Observed-Adverse-Effect Level · Toxicity Tests · Animalia
[Abstract]

19 Subacute toxicity of a mixture of nine chemicals in rats: Detecting interactive effects with a fractionated two-level factorial design
article 1997    
Author: Groten, J.P. · Schoen, E.D. · Bladeren, P.J. van · Kuper, C.F. · Zorge, J.A. van · Feron, V.J.
Keywords: Acetylsalicylic acid · Butylated hydroxyanisole · Cadmium chloride · Dichloromethane · Formaldehyde · Loperamide · Phthalic acid bis(2 ethylhexyl) ester · Spermine · Stannous chloride · Animal experiment · Controlled study · Drug mixture · Factorial analysis · Male · Model · Nonhuman · Oral drug administration · Prognosis · Rat · Risk assessment · Theory · Toxicity · Administration, Inhalation · Animals · Blood Chemical Analysis · Body Weight · Drug Combinations · Drug Interactions · Epithelium · Hazardous Substances · Hematologic Tests · Hypertrophy · Liver · Male · Models, Statistical · Multiple Chemical Sensitivity · Nasal Cavity · No-Observed-Adverse-Effect Level · Organ Size · Rats · Rats, Wistar
[Abstract]

20 Long-term, low-level exposure of guinea pigs and marmosets to sarin vapor in air: Lowest observable effect level
article 2003    
Author: Helden, H.P.M. van · Trap, H.C. · Oostdijk, J.P. · Kuijpers, W.C. · Langenberg, J.P. · Benschop, H.P.
Keywords: Fluoride-induced reactivation · Guinea pigs · Internal dose · Lowest observable effect level (LOEL) · Marmosets · Nerve agent · O-Isopropyl methylphosphonofluoridate · Occupational exposure limits · Respiratory exposure · Sarin · Worker population limit (WPL) · Cholinesterase · Sarin · Animal experiment · Animal trapping · Article · Binding site · Chemical warfare · Cholinesterase inhibition · Controlled study · Enzyme activity · Gas chromatography · Gas mask · Guinea pig · Long term exposure · Male · Marmoset · Measurement · Nonhuman · Occupational exposure · Species comparison · Vaporization · Worker · Animals · Atmosphere Exposure Chambers · Callithrix · Dose-Response Relationship, Drug · Female · Gases · Guinea Pigs · Male · No-Observed-Adverse-Effect Level · Sarin · Threshold Limit Values · Volatilization · Animalia · Cavia · Cholinesterase, 9001-08-5 · Sarin, 107-44-8 · Gases
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 32 found. Next | Sort by date