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1 Extracellular proteolysis and the migrating vascular smooth muscle cell
article 1996    
Author: Leeuwen, R.T.J. van
Keywords: Biology · metalloproteinase · plasminogen activator · artery · cell migration · priority journal · protein degradation · review · smooth muscle fiber · vascular smooth muscle
[Abstract]

2 A sensitive bioimmunoassay for thrombin-cleaved two-chain urokinase-type plasminogen activator in human body fluids
article 1996    
Author: Braat, E.A.M. · Nauland, U. · Dooijewaard, G. · Rijken, D.C.
Keywords: Biology · Cathepsin · Urokinase · Bioassay · Blood level · Clinical trial · Controlled clinical trial · Controlled study · Immunoassay · Protein degradation · Rheumatoid arthritis · Sepsis · Synovial fluid level · Body Fluids · Humans · Immunoenzyme Techniques · Sensitivity and Specificity · Thrombin · Urinary Plasminogen Activator
[Abstract]

3 Markers of fibrinolytic potency and clotting activation in stable angina pectoris : Role of urokinase, assessment of atrioventricular differences and correlation with coronary patency
article 1999    
Author: Páramo, U.A. · Panizo, C. · Montes, R. · Orbe, J. · Alegría, E. · Martínez-Caro, D. · Dooijewaard, G.
Keywords: Biology · biochemical marker · urokinase · adult · aged · angina pectoris · blood clotting · blood sampling · coronary blood vessel · drug effect · drug potency · enzyme activity · female · fibrinolysis · graft patency · hemostasis · human · major clinical study · male · protein degradation · thrombogenesis
[Abstract]

4 Efficient degradation of gluten by a prolyl endoprotease in a gastrointestinal model: Implications for coeliac disease
article 2008    
Author: Mitea, C. · Havenaar, R. · Wouter Drijfhout, J. · Edens, L. · Dekking, L. · Koning, F. · Dekking, E.H.A.
Keywords: Health · Physiological Sciences · epitope · gliadin · gluten · glutenin · monoclonal antibody · proline · prolyl endopeptidase · article · Aspergillus niger · bread · celiac disease · cell proliferation · gastrointestinal tract · gluten free diet · immunogenicity · priority journal · protein degradation · quality of life · T lymphocyte · Western blotting · Aspergillus niger · Celiac Disease · Female · Gluten · Humans · Male · Models, Immunological · Serine Endopeptidases · Stomach · Food and Nutrition · Healthy Living
[Abstract]

5 Expression of human lymphotoxin alpha in Aspergillus niger
article 2000    
Author: Krasevec, N. · Hondel, C.A.M.J.J. van de · Komel, R.
Keywords: Medicine · Geneeskunde · Pathology · Aspergillus niger · Codon usage · Heterologous protein secretion · LTα · TNFα · Complementary DNA · Lymphotoxin · Tumor necrosis factor alpha · Aspergillus niger · Codon usage · Conference paper · Controlled study · DNA sequence · Gene control · Gene fusion · Genetic transcription · Human · Nonhuman · Priority journal · Protein degradation · Protein secretion · Artificial Gene Fusion · Aspergillus niger · Blotting, Northern · Glucan 1,4-alpha-Glucosidase · Humans · Lymphotoxin-alpha · RNA, Messenger
[Abstract]

6 Stimulation of tissue-type plasminogen activator expression by retinoic acid in human endothelial cells requires retinoic acid receptor β2 induction
article 1996    
Author: Lansink, M. · Kooistra, T.
Keywords: Biology · Antisense oligodeoxynucleotide · Cycloheximide · Tetinoic acid receptor · Alternative rna splicing · Antibody response · Cell stimulation · competitive inhibition · Endothelium cell · Enzyme active site · Fibrinolysis · Gene induction · Human cell · Protein degradation · Base Sequence · Benzoates · Cells, Cultured · Chromans · Cycloheximide · DNA, Complementary · Endothelium, Vascular · Gene Expression Regulation · Humans · Molecular Sequence Data · Oligonucleotides, Antisense · Protein Synthesis Inhibitors · Receptors, Retinoic Acid · Tissue Plasminogen Activator · Tretinoin · Umbilical Veins
[Abstract]

7 Analysis of heterologous protein production in defined recombinant Aspergillus awamori strains
article 1996    
Author: Gouka, R.J. · Punt, P.J. · Hessing, J.G.M. · Hondel, C.A.M.J.J. van den
Keywords: Nutrition · aspergillus awamori · enzyme activity · fungal genetics · northern blotting · protein analysis · protein degradation · protein metabolism · saccharomyces cerevisiae · signal transduction · steady state · Aspergillus · Base Sequence · Carrier Proteins · DNA, Recombinant · Gene Expression · Genes, Fungal · Heat-Shock Proteins · Humans · Interleukin-6 · Molecular Chaperones · Recombinant Proteins · Recombination, Genetic · RNA, Messenger
[Abstract]

8 Apparent ileal dry matter and crude protein digestibility of rations fed to pigs and determined with the use of chromic oxide (Cr2O3) and acid-insoluble ash as digestive markers
article 1996    
Author: Leeuwen, P. van · Veldman, A. · Boisen, S. · Deuring, K. · Kempen, G.J.M. van · Derksen, G.B. · Verstegen, M.W.A. · Schaafsma, G.
Keywords: Chemistry · Digestive markers · Ileal digestibilty · Pigs · Chromic oxide · Gluten · Marker · Nitrogen · Unclassified drug · Animal experiment · Animal food · Ash · Bran · Cannula · Cecum · Controlled study · Nonhuman · Protein degradation · Animal Feed · Animals · Biological Markers · Body Weight · Chromium Compounds · Dietary Proteins · Digestion · Evaluation Studies · Ileum · Male · Nitrogen · Postprandial Period · Soybeans · Swine · Triticum · Animalia · Glycine max · Sus scrofa · Triticum aestivum
[PDF] [Abstract]

9 Regulation of plasminogen activation, matrix metalloproteinases and urokinase-type plasminogen activator-mediated extracellular matrix degradation in human osteosarcoma cell line MG63 by interleukin-1 alpha
article 1995    
Author: Bart, A.C.W. de · Quax, P.H.A. · Löwik, C.W.G.M. · Verheijen, J.H.
Keywords: Health · collagenase · gelatinase · interleukin 1alpha · messenger rna · metalloproteinase · plasminogen · stromelysin · tissue inhibitor of metalloproteinase · urokinase · animal cell · animal tissue · article · bone matrix · bone turnover · calvaria · cattle · controlled study · extracellular matrix · human · human cell · mouse · nonhuman · osteolysis · osteosarcoma · protein degradation · Extracellular Matrix · Human · Interleukin-1 · Metalloendopeptidases · Osteoblasts · Osteosarcoma · Plasminogen Activators · Plasminogen Inactivators · Support, Non-U.S. Gov't · Tumor Cells, Cultured · Urinary Plasminogen Activator
[Abstract]

10 Degradation of tissue-type plasminogen activator by human monocyte- derived macrophages is mediated by the mannose receptor and by the low- density lipoprotein receptor-related protein
article 1995    
Author: Noorman, F. · Braat, E.A.M. · Rijken, D.C.
Keywords: Biology · aminocaproic acid · lipopolysaccharide · low density lipoprotein receptor · mannose receptor · receptor protein · tissue plasminogen activator · article · controlled study · hemostasis · human · human cell · macrophage · molecular interaction · normal human · priority journal · protein degradation · receptor affinity · Cell Differentiation · Cells, Cultured · Dexamethasone · Human · LDL-Receptor Related Protein 1 · Lipopolysaccharides · Macrophages · Monocytes · Receptors, Cell Surface · Receptors, Immunologic · Support, Non-U.S. Gov't · Tissue Plasminogen Activator
[Abstract]

11 An enzyme immunoassay for polymorphonuclear leucocyte-mediated fibrinogenolysis
article 1997    
Author: Bos, R. · Leuven, C.J.M. van · Stolk, J. · Hiemstra, P.S. · Ronday, H.K. · Nieuwenhuizen, W.
Keywords: Biology · Monoclonal antibody · Polymorphonuclear leucocytes · Pulmonary emphysema · Biochemical marker · Elastase · Monoclonal antibody · Adult · Clinical article · Controlled study · Enzyme immunoassay · Female · Lung emphysema · Male · Monitoring · Protein degradation · Rheumatoid arthritis · Sepsis · Antibodies, Monoclonal · Antibody Specificity · Enzyme-Linked Immunosorbent Assay · Fibrin Fibrinogen Degradation Products · Fibrinogen · Fibrinolysis · Humans · Leukocyte Elastase · Neutrophils · Serine Endopeptidases
[Abstract]

12 Reduced very-low-density lipoprotein fractional catabolic rate in apolipoprotein C1-deficient mice
article 1997    
Author: Jong, M.C. · Ree, J.H. van · Dahlmans, V.E.H. · Frants, R.R. · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · very low density lipoprotein · animal experiment · catabolism · controlled study · human · hyperlipoproteinemia · lipolysis · metabolism · mouse · nonhuman · priority journal · protein degradation · protein metabolism · transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins B · Apolipoproteins C · Cholesterol, Dietary · Female · Lipolysis · Lipoproteins, VLDL · Mice · Mice, Mutant Strains · Triglycerides · Ultracentrifugation · Animalia · Mus musculus
[Abstract]

13 Low-density lipoproteins are degraded in HepG2 cells with low efficiency
article 1993    
Author: Lombardi, P. · Mulder, M. · Wit, E. de · Berkel, T.J.C. van · Frants, R.R. · Havekes, L.M.
Keywords: Low density lipoprotein · Low density lipoprotein receptor · Cell density · Cell fractionation · Comparative study · Density gradient centrifugation · Endosome · Hepatoma cell · Human cell · Internalization · Isotope labeling · Lipoprotein metabolism · Protein degradation · Receptor down regulation · Biological Transport · Cell Aggregation · Cell Line · Cells, Cultured · Down-Regulation · Fibroblasts · Human · Iodine Radioisotopes · Kinetics · Lipoproteins, LDL · Liver · Lysosomes · Receptors, LDL · Support, Non-U.S. Gov't
[Abstract]

14 Inefficient degradation of triglyceride-rich lipoprotein by HepG2 cells is due to a retarded transport to the lysosomal compartment
article 1993    
Author: Lombardi, P. · Mulder, M. · Boom, H. van der · Frants, R.R. · Havekes, L.M.
Keywords: Cholesterol acyltransferase · Lipoprotein · Lipoprotein receptor · Low density lipoprotein · Triacylglycerol · Very low density lipoprotein · Cholesterol blood level · Density gradient centrifugation · Endosome · Enzyme activity · Homeostasis · Human cell · Lipid transport · Protein binding · Protein degradation · Biological Transport · Cell Compartmentation · Cell Line · Cholesterol · Endocytosis · Esterification · Human · Lipoprotein Lipase · Lipoproteins, LDL · Lipoproteins, VLDL · Lysosomes · Sterol O-Acyltransferase · Support, Non-U.S. Gov't · Triglycerides
[PDF] [Abstract]

15 Alirocumab inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin
article 2014    
Author: Kühnast, S. · Hoorn, J.W.A. van der · Pieterman, E.J. · Hoek, A.M. van den · Sasiela, W.J. · Gusarova, V. · Peyman, A. · Schäfer, H.L. · Schwahn, U. · Jukema, J.W. · Princen, H.M.G.
Keywords: Biology · 3Leiden.CETP mice · APOE · Atorvastatin · Proprotein convertase subtilisin/kexin type 9 · Alirocumab · Apolipoprotein E · Atorvastatin · Bile acid · Cholesterol · Collagen · Low density lipoprotein receptor · Sterol · Triacylglycerol · Animal experiment · Animal model · Atherosclerosis · Atherosclerotic plaque · Controlled study · Disease severity · Dose response · Drug effect · Drug potentiation · Drug safety · Fat content · Female · Lipid blood level · Monocyte · Monotherapy · Mouse · Nonhuman · Protein degradation · Smooth muscle fiber · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

16 Biological evaluation of Tyr6 and Ser7 modified drosocin analogues
article 2005    
Author: Visser, P.C. de · Hooft, P.A.V. van · Vries, A.-M. de · Jong, A. de · Marel, G.A. van der · Overkleeft, H.S. · Noort, D.
Keywords: Antibiotic agent · Amino acid substitution · Amino terminal sequence · Article · Controlled study · Drug screening · Drug stability · Drug synthesis · Nonhuman · Protein degradation · Amino Acid Sequence · Glycopeptides · Humans · Microbial Sensitivity Tests · Molecular Sequence Data · Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization · Chemicals · Drosocin, 179048-25-0 · Serine, 56-45-1, 6898-95-9 · Tyrosine, 16870-43-2, 55520-40-6, 60-18-4 · Drosocin, 149924-99-2 · Glycopeptides · Serine, 56-45-1 · Tyrosine, 55520-40-6
[Abstract]

17 Strongly increased levels of fibrinogen elastase degradation products in patients with ischemic stroke
article 2008    
Author: Lau, L.M.L. de · Cheung, E.Y.L. · Kluft, C. · Leebeek, F.W.G. · Meijer, P. · Laterveer, R. · Dippel, D.W.J. · Maat, M.P.M.de
Keywords: Biology · Biomedical Research · Elastase · Epidemiology · Fibrinogen degradation products · Leucocyte activation · Stroke · C reactive protein · elastase · fibrinogen · adult · article · cardiovascular risk · cerebrovascular accident · controlled study · convalescence · disease course · female · fibrinogen blood level · human · major clinical study · male · priority journal · protein degradation · stroke patient · Adult · Aged · Biological Markers · C-Reactive Protein · Case-Control Studies · Female · Fibrin Fibrinogen Degradation Products · Fibrinogen · Humans · Ischemic Attack, Transient · Lymphocyte Activation · Male · Middle Aged · Odds Ratio · Pancreatic Elastase · Risk · Stroke
[Abstract]

18 Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: The role of advanced glycation end products
article 2001    
Author: Groot, J. de · Verzijl, N. · Wenting-Van Wijk, M.J.G. · Bank, R.A. · Lafeber, F.P.J.G. · Bijlsma, J.W.J. · Tekoppele, J.M.
Keywords: Health Biology · Biomedical Research · glycosaminoglycan · matrix metalloproteinase · pentosidine · adult · aged · article · articular cartilage · cartilage degeneration · clinical article · colorimetry · controlled study · disease course · female · high performance liquid chromatography · human · male · osteoarthritis · priority journal · protein degradation · rheumatoid arthritis · synovial fluid · Adult · Aged · Aged, 80 and over · Aging · Animals · Arginine · Arthritis, Rheumatoid · Cartilage, Articular · Cattle · Chromatography, High Pressure Liquid · Glycosaminoglycans · Humans · Knee Joint · Lysine · Matrix Metalloproteinases · Middle Aged · Osteoarthritis, Knee · Phenylmercuric Acetate · Ribose · Synovial Fluid
[Abstract]

19 The metabolic activity of fecal microbiota from healthy individuals and patients with inflammatory bowel disease
article 2004    
Author: Nuenen, M.H.M.C. van · Venema, K. · Woude, J.C.J. van der · Kuipers, E.J.
Keywords: Nutrition · Physiological Sciences · Fermentation · In vitro model · Inflammatory bowel disease · Metabolites · Microbial activity · ammonia · branched chain fatty acid · fatty acid · lactic acid · phenol derivative · short chain fatty acid · unclassified drug · adult · article · carbohydrate metabolism · chronicity · clinical article · controlled study · enteritis · fatty acid synthesis · feces microflora · fermentation · human · in vitro study · metabolite · microbial metabolism · model · nonhuman · normal human · priority journal · protein degradation · Adult · Ammonia · Bacteria · Colitis, Ulcerative · Colon · Crohn Disease · Fatty Acids · Fatty Acids, Volatile · Feces · Fermentation · Humans · Lactic Acid · Middle Aged
[Abstract]

20 Reversible denaturation of Brazil nut 2S albumin (Ber e1) and implication of structural destabilization on digestion by pepsin
article 2005    
Author: Koppelman, S.J. · Nieuwenhuizen, W.F. · Gaspari, M. · Knippels, L.M.J. · Penninks, A.H. · Knol, E.F. · Hefle, S.L. · Jongh, H.H.J.de
Keywords: Health Toxicology · Food technology · Allergenicity · Denaturation · Pepsin · Protein folding · Protein stability · albumin · guanidine · pepsin A · alkylation · allergenicity · alpha helix · article · Brazil nut · chemical procedures · circular dichroism · energy · food composition · gel electrophoresis · gel permeation chromatography · infrared spectroscopy · mass spectrometry · pH measurement · protein degradation · protein denaturation · protein folding · protein stability · protein structure · temperature dependence · Albumins · Bertholletia · Pepsin A · Plant Proteins · Protein Denaturation · Protein Precursors · Bertholletia excelsa · Ziziphus mauritiana
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 47 found. Next | Sort by date