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1 Identification of a novel protein antigen encoded by a Mycobacterium tuberculosis-specific RD1 region gene
article 1999    
Author: Ahmad, S. · Amoudy, H.A. · Thole, J.E.R. · Young, D.B. · Mustafa, A.S.
Keywords: Health · BCG vaccine · Antibodies, Bacterial · Antigens, Bacterial · Bacterial Proteins · Cloning, Molecular · Escherichia coli · Gene Expression · Genes, Bacterial · Humans · Immunoblotting · Mycobacterium tuberculosis · Open Reading Frames · Recombinant Fusion Proteins · Tuberculosis
[Abstract]

2 Recent advances in the large-scale production of antibody fragments using lower eukaryotic microorganisms
article 1998    
Author: Frenken, L.G.J. · Hessing, J.G.M. · Hondel, C.A.M.J.J. van den · Verrips, C.T.
Keywords: Nutrition · Monoclonal antibody · Antibody production · Aspergillus awamori · Controlled study · Cost · Eukaryote · Fungus · Mouth hygiene · Nonhuman · Priority journal · Review · Saccharomyces cerevisiae · Animals · Antibodies, Monoclonal · Aspergillus · Biotechnology · Fermentation · Fungi · Humans · Immunoglobulin Fragments · Recombinant Fusion Proteins · Saccharomyces cerevisiae

3 The S-layer protein of Lactobacillus acidophilus ATCC 4356 : identification and characterisation of domains responsible for S-protein assembly and cell wall binding
article 2001    
Author: Smit, E. · Oling, F. · Demel, R. · Martinez, B. · Pouwels, P.H.
Keywords: Biology · Amino Acid Sequence · Bacterial Proteins · Cell Wall · Crystallization · Electrophoresis, Polyacrylamide Gel · Escherichia coli · Lactobacillus acidophilus · Membrane Glycoproteins · Membrane Proteins · Microscopy, Electron · Models, Molecular · Molecular Sequence Data · Peptide Fragments · Phosphatidylserines · Protein Binding · Protein Structure, Quaternary · Protein Structure, Secondary · Protein Structure, Tertiary · Recombinant Fusion Proteins · Sequence Alignment · Sequence Analysis, Protein · Solutions · Trypsin · Escherichia coli · Lactobacillus acidophilus · Lactobacillus casei · Lactobacillus crispatus · Lactobacillus helveticus
[Abstract]

4 Instruments for oral disease-intervention strategies : recombinant Lactobacillus casei expressing tetanus toxin fragment C for vaccination or myelin proteins for oral tolerance induction in multiple sclerosis
article 1999    
Author: Maassen, C.B.M. · Laman, J.D. · Heijne den Bak-Glashouwer, M.J. · Tielen, F.J. · Holten-Neelen, J.C.P.A. van · Hoogteijling, L. · Antonissen, C. · Leer, R.J. · Pouwels, P.H. · Boersma, W.J.A. · Shaw, D.M.
Keywords: Experimental autoimmune/allergic encephalomyelitis (EAE) · Heterologous gene expression · Mucosal vaccines · lactobacillus vaccine · Myelin protein · Recombinant vaccine · Antibody response · Immunization · Immunoblotting · Immunogenicity · Nonhuman · Oral drug administration · Priority journal · Tetanus · Vaccination · Administration, Oral · Animals · Bacterial Vaccines · Cattle · Flow Cytometry · Genetic Vectors · Guinea Pigs · Humans · Immune Tolerance · Immunohistochemistry · Lactobacillus casei · Mice · Multiple Sclerosis · Myelin Basic Proteins · Peptide Fragments · Rabbits · Recombinant Fusion Proteins · Tetanus · Tetanus Toxin
[Abstract]

5 Selection of Arabidopsis mutants overexpressing genes driven by the promoter of an auxin-inducible glutathione S-transferase gene
article 1999    
Author: Kop, D.A.M. van der · Schuyer, M. · Pinas, J.E. · Zaal, B.J. van der · Hooykaas, P.J.J.
Keywords: Nutrition · Arabidopsis thaliana · Auxin-responsive gene expression · Developmental mutants · Glutathione S-transferase · GST · Gup mutant · Auxin · Beta glucuronidase · Gene expression · Glutathione transferase · Kanamycin · Reporter gene · Transgenic plant · Arabidopsis · Chromosome Mapping · Crosses, Genetic · DNA, Bacterial · Enzyme Induction · Ethyl Methanesulfonate · Gene Expression Regulation, Plant · Genes, Plant · Glutathione Transferase · Indoleacetic Acids · Mutagenesis · Mutagens · Mutation · Phenotype · Plants, Genetically Modified · Promoter Regions (Genetics) · Recombinant Fusion Proteins · Up-Regulation
[Abstract]

6 Kinetics of mRNA and protein synthesis of genes controlled by the 1,4- β-endoxylanase A promoter in controlled fermentations of Aspergillus awamori
article 1996    
Author: Gouka, R.J. · Stam, H. · Fellinger, A.J. · Muijsenberg, R.J.G.T. · Wijngaard, A.J. van de · Punt, P.J. · Musters, W. · Hondel, C.A.M.J.J. van den
Keywords: Nutrition · Triacylglycerol lipase · Cell culture · Enzyme activity · Enzyme analysis · Gene expression · Gene expression regulation · Glucose metabolism · Promoter region · Protein synthesis · Rna analysis · Aspergillus · Endo-1,4-beta Xylanases · Fermentation · Gene Expression Regulation, Fungal · Glucose · Glucuronidase · Kinetics · Lipase · Promoter Regions (Genetics) · Protein Biosynthesis · Recombinant Fusion Proteins · RNA, Messenger · Xylose · Xylosidases · Aspergillus awamori · Escherichia coli · Thermomyces lanuginosus
[Abstract]

7 Adenoviral expression of a urokinase receptor - Targeted protease inhibitor inhibits neointima formation in murine and human blood vessels
article 2001    
Author: Quax, P.H.A. · Lamfers, M.L.M. · Lardenoye, J.H.P. · Grimbergen, J.M. · Vries, M.R. de · Slomp, J. · Ruiter, M.C. de · Kockx, M.M. · Verheijen, J.H. · Hinsbergh, V.W.M. van
Keywords: Adenoviridae · Animals · Aprotinin · Blood Vessels · Cattle · CHO Cells · Cricetinae · Femoral Artery · Femoral Vein · Gene Expression · Genetic Vectors · Humans · Mice · Mice, Inbred C57BL · Muscle, Smooth, Vascular · Organ Culture Techniques · Peptide Fragments · Plasmin · Recombinant Fusion Proteins · Saphenous Vein · Transfection · Tunica Intima · Urinary Plasminogen Activator
[Abstract]

8 Fibrinolytic activity of human mesothelial cells is counteracted by rapid uptake of tissue-type plasminogen activator
article 1999    
Author: Sitter, T. · Toet, K. · Quax, P. · Kooistra, T.
Keywords: Antibodies · Biological Transport, Active · Carrier Proteins · Cells, Cultured · Chloroquine · Culture Media, Conditioned · Epithelial Cells · Fibrinolysis · Gene Expression · Glutathione Transferase · Humans · Iodine Radioisotopes · LDL-Receptor Related Protein 1 · Lectins, C-Type · Mannose-Binding Lectins · Plasminogen Activator Inhibitor 1 · Receptors, Cell Surface · Receptors, Immunologic · Receptors, LDL · Recombinant Fusion Proteins · RNA, Messenger · Tissue Plasminogen Activator · Tumor Necrosis Factor-alpha · Urinary Plasminogen Activator
[Abstract]

9 Two novel, putatively cell wall-associated and glycosylphosphatidylinositol-anchored α-glucanotransferase enzymes of Aspergillus niger
article 2007    
Author: Kaaij, R.M. van der · Yuan, X.L. · Franken, A. · Ram, A.F.J. · Punt, P.J. · Maarel, M.J.E.C. van der · Dijkhuizen, L.
Keywords: Biology · Food technology · 4 alpha glucanotransferase · 4 alpha-glucanotransferase · fungal protein · glycogen debranching enzyme · glycosylphosphatidylinositol · hybrid protein · isoenzyme · maltooligosaccharides · oligosaccharide · unclassified drug · amino acid sequence · article · Aspergillus niger · cell wall · chemistry · classification · cytology · enzymology · genetics · metabolism · molecular genetics · nucleotide sequence · phylogeny · sequence alignment · sequence homology · Amino Acid Sequence · Aspergillus niger · Base Sequence · Cell Wall · Fungal Proteins · Glycogen Debranching Enzyme System · Glycosylphosphatidylinositols · Isoenzymes · Molecular Sequence Data · Oligosaccharides · Phylogeny · Recombinant Fusion Proteins · Sequence Alignment · Sequence Homology, Amino Acid · Aspergillus niger
[Abstract]

10 Analysis of the role of the gene bipA, encoding the major endoplasmic reticulum chaperone protein in the secretion of homologous and heterologous proteins in black Aspergilli
article 1998    
Author: Punt, P.J. · Gemeren, I.A. van · Drint-Kuijvenhoven, J. · Hessing, J.G.M. · Muijlwijk van - Harteveld, G.M. · Beijersbergen, A. · Verrips, C.T. · Hondel, C.A.M.J.J. van den
Keywords: Nutrition · Binding protein · Chaperone · Glucan 1,4 alpha glucosidase · Recombinant protein · Aspergillus awamori · Aspergillus niger · Endoplasmic reticulum · Fungal genetics · Gene fusion · Gene overexpression · Nonhuman · Promoter region · Protein secretion · Animals · Antibody Specificity · Artificial Gene Fusion · Aspergillus · Aspergillus niger · Blotting, Northern · Blotting, Western · Cloning, Molecular · Fungal Proteins · Gene Expression Regulation, Fungal · Genes, Fungal · Glucan 1,4-alpha-Glucosidase · HSP70 Heat-Shock Proteins · Rabbits · Recombinant Fusion Proteins · Aspergillus · Aspergillus awamori · Aspergillus niger · Fungi
[Abstract]

11 Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor : Contribution to the hypertriglyceridemic action of retinoids
article 1998    
Author: Vu-Dac, N. · Gervois, P. · Torra, I.P. · Fruchart, J.C. · Kosykh, V. · Kooistra, T. · Princen, H.M.G. · Dallongeville, J. · Staels, B.
Keywords: Health · Gene regulation · Hyperlipidemia · Nuclear receptors · Retinoids · Triglycerides · Adult · Apolipoprotein C-III · Apolipoproteins C · Benzoates · Carcinoma, Hepatocellular · Cells, Cultured · Dimerization · Double-Blind Method · Gene Expression Regulation · Hela Cells · Humans · Hypertriglyceridemia · Isotretinoin · Liver · Liver Neoplasms · Male · Mutagenesis, Site-Directed · Promoter Regions (Genetics) · Receptors, Cytoplasmic and Nuclear · Receptors, Retinoic Acid · Recombinant Fusion Proteins · Regulatory Sequences, Nucleic Acid · Retinoid X Receptors · Retinoids · Tetrahydronaphthalenes · Transcription Factors · Transcription, Genetic · Transfection · Tumor Cells, Cultured
[PDF] [Abstract]

12 An epitope delivery system for use with recombinant mycobacteria
article 1998    
Author: Hetzel, C. · Janssen, R. · Ely, S.J. · Kristensen, N.M. · Bunting, K. · Cooper, J.B. · Lamb, J.R. · Young, D.B. · Thole, J.E.R.
Keywords: Health · Mycobacterium antigen · Antigen expression · Immunogenicity · Mycobacterium tuberculosis · Mycobacterium vaccae · Nonhuman · Protein targeting · Vaccine production · Amino Acid Sequence · Animals · Antigens, Bacterial · Antigens, Dermatophagoides · Bacterial Proteins · CD4-Positive T-Lymphocytes · CD8-Positive T-Lymphocytes · Cloning, Molecular · Epitopes, T-Lymphocyte · Female · Gene Expression · Glycoproteins · Interferon Type II · Mice · Mice, Inbred C57BL · Molecular Sequence Data · Mycobacterium · Mycobacterium bovis · Recombinant Fusion Proteins · Recombination, Genetic · Superoxide Dismutase
[PDF] [Abstract]

13 Gene transfer of the urokinase-type plasminogen activator receptor-targeted matrix metalloproteinase inhibitor TIMP-1.ATF suppresses neointima formation more efficiently than tissue inhibitor of metalloproteinase-1
article 2002    
Author: Lamfers, M.L.M. · Grimbergen, J.M. · Aalders, M.C. · Havenga, M.J. · Vries, M.R. de · Huisman, L.G.M. · Hinsbergh, V.W.M. van · Quax, P.H.A.
Keywords: Biology · Adenovirus · Matrix metalloproteinases · Neointima formation · Plasmin(ogen) · Urokinase-type plasminogen activator · Adenovirus · Adenoviridae · Animals · Cell Division · Cell Membrane · Cell Movement · Cells, Cultured · CHO Cells · Collagenases · Cricetinae · Culture Media, Conditioned · Enzyme Activation · Flow Cytometry · Gene Transfer Techniques · Humans · Matrix Metalloproteinase 13 · Muscle, Smooth, Vascular · Protein Structure, Tertiary · Receptors, Cell Surface · Recombinant Fusion Proteins · RNA, Messenger · Saphenous Vein · Tissue Inhibitor of Metalloproteinase-1 · Tunica Intima · Urinary Plasminogen Activator
[Abstract]

14 The role of the Aspergillus niger furin-type protease gene in processing of fungal proproteins and fusion proteins: Evidence for alternative processing of recombinant (fusion-) proteins
article 2003    
Author: Punt, P.J. · Drint-Kuijvenhoven, A. · Lokman, B.C. · Spencer, J.A. · Jeenes, D. · Archer, D.A. · Hondel, C.A.M.J.J. van den
Keywords: Biology · Biotechnology · Filamentous fungi · Fusion-proteins · Protease · Protein processing · Protein secretion · Secretion carrier · Biotechnology · Genes · Growth kinetics · Mutagenesis · Proteins · Cleavage sites · Genetic engineering · arginine · aspergillopepsin · fungal protein · furin · glucan 1,4 alpha glucosidase · hybrid protein · lysine · protein precursor · proteinase · recombinant protein · unclassified drug · allele · amino acid composition · article · Aspergillus niger · controlled study · fungal gene · fungal strain · fungus mutant · gene deletion · gene disruption · gene function · genetic code · genetic recombination · molecular cloning · nonhuman · nucleotide sequence · priority journal · protein degradation · protein processing · wild type · Aspergillus niger · Endopeptidases · Fungal Proteins · Furin · Gene Expression Regulation, Enzymologic · Gene Expression Regulation, Fungal · Protein Processing, Post-Translational · Recombinant Fusion Proteins · Trans-Activation (Genetics) · Aspergillus · Aspergillus niger · Fungi
[Abstract]

15 Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons
article 2000    
Author: Kappers, W.A. · Och, F.M.M. van · Groene, E.M. de · Horbach, G.J.
Keywords: Nutrition · Acetyltransferase · Amestest · AminoPAHs · Cytochrome P450 · HPRT · Mutagenicity · NIH/3T3 cells · NitroPAHs · Shuttle vector · V79 cells · Cytochrome P450 · Polycyclic aromatic hydrocarbon · Animal cell · Cell strain 3T3 · Controlled study · Enzyme activity · Gene locus · In vitro study · Mouse · Mutagenicity · Nonhuman · Priority journal · Reaction analysis · Reporter gene · Shuttle vector · 3T3 Cells · Animals · Cell Line · Cell Survival · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Enzyme Inhibitors · Ethyl Methanesulfonate · Fluorenes · Humans · Hypoxanthine Phosphoribosyltransferase · Ketoconazole · Lac Operon · Mice · Microsomes, Liver · Mutagenicity Tests · Mutagens · Mutation · Polycyclic Hydrocarbons, Aromatic · Pyrenes · Rats · Recombinant Fusion Proteins · Salmonella typhimurium · Theophylline · Animalia · Cricetinae · Cricetulus griseus · Eukaryota · Salmonella typhimurium · Typhimurium
[Abstract]

16 Molecular cloning, functional characterization and expression analysis of a novel monosaccharide transporter gene OsMST6 from rice (Oryza sativa L.)
article 2008    
Author: Wang, Y. · Xiao, Y. · Zhang, Y. · Chai, C. · Wei, G. · Wei, X. · Xu, H. · Wang, M. · Ouwerkerk, P.B.F. · Zhu, Z.
Keywords: Biomedical Research · cDNA cloning · Expression pattern · Monosaccharide transporter · Oryza · Seed development · complementary DNA · glucose transporter · hybrid protein · messenger RNA · plant DNA · vegetable protein · article · DNA sequence · gene expression · genetics · in situ hybridization · isolation and purification · molecular cloning · molecular genetics · nucleotide sequence · phylogeny · physiology · plant gene · reverse transcription polymerase chain reaction · rice · Saccharomyces cerevisiae · sequence alignment · Base Sequence · Cloning, Molecular · DNA, Complementary · DNA, Plant · Gene Expression · Genes, Plant · In Situ Hybridization · Molecular Sequence Data · Monosaccharide Transport Proteins · Oryza sativa · Phylogeny · Plant Proteins · Recombinant Fusion Proteins · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger · Saccharomyces cerevisiae · Sequence Alignment · Sequence Analysis, DNA · Oryza · Oryza sativa · Saccharomyces cerevisiae
[Abstract]

17 Regulation of expression of the Aspergillus niger benzoate para-hydroxylase cytochrome P450 system
article 2000    
Author: Brink, J.M. van den · Punt, P.J. · Gorcom, R.F.M. van · Hondel, C.A.M.J.J. van den
Keywords: Nutrition · Aspergillus niger · Benzoate · Cytochrome P450 · Post-transcriptional regulation · Benzoic acid · Cytochrome P450 · Cytochrome P450 reductase · Oxygenase · Aspergillus niger · DNA responsive element · Enzyme analysis · Enzyme regulation · Gene expression regulation · Gene function · Gene induction · Genetic transcription · Hydroxylation · Nonhuman · Nucleotide sequence · Priority journal · Promoter region · Protein induction · Amino Acid Sequence · Aspergillus niger · Base Sequence · Benzoates · Enzyme Induction · Gene Expression Regulation, Bacterial · Gene Expression Regulation, Enzymologic · Mixed Function Oxygenases · Molecular Sequence Data · NADH, NADPH Oxidoreductases · NADPH-Ferrihemoprotein Reductase · Oxygenases · Promoter Regions (Genetics) · Recombinant Fusion Proteins · Restriction Mapping · Sequence Alignment · Sequence Homology, Amino Acid · Transcription, Genetic · Aspergillus niger · Eukaryota · Fungi
[Abstract]

18 Production of bifunctional proteins by Aspergillus awamori: Llama variable heavy chain antibody fragment (VHH) R9 coupled to Arthromyces ramosus peroxidase (ARP)
article 2005    
Author: Joosten, V. · Roelofs, M.S. · Dries, N. van den · Goosen, T. · Verrips, C.T. · Hondel, C.A.M.J.J. van den · Lokman, B.C.
Keywords: Biology · Biotechnology · Antibodies · Antigens · Cytology · Dyes · Enzyme kinetics · Enzymes · Fungi · Genes · Proteins · Magic Bullets · Arthromyces ramosus peroxidase (ARP) · Aspergillus awaromi · Fusion proteins · Heterologus protein production · Llama variable heavy chain antibody fragments (VHH) · Genetic engineering · hybrid protein · carboxy terminal sequence · comparative study · culture medium · enzyme activity · enzyme linked immunosorbent assay · gene cassette · genetic code · genetics · nonhuman protein binding · protein expression · Animals · Antibodies, Monoclonal · Aspergillus · Camelids, New World · Fungal Proteins · Fungi, Unclassified · Immunoglobulin Heavy Chains · Immunoglobulin Variable Region · Peroxidase · Recombinant Fusion Proteins · Arthromyces ramosus · Lama glama
[Abstract]

19 Recombinant Lactobacillus plantarum inhibits house dust mite-specific T-cell responses
article 2001    
Author: Kruisselbrink, A. · Heijne Den Bak-Glashouwer, M.J. · Havenith, C.E.G. · Thole, J.E.R. · Janssen, R.
Keywords: Health · Allergy · Mucosal immunity · Th1/Th2 · Antibody · Epitope · Gamma interferon · Peptide · Peptide der p 1 · Unclassified drug · Allergic disease · Animal cell AAnimal experiment · Animal model · Animal tissue · Antibody response · Controlled study · Cytokine production · Dermatophagoides pteronyssinus · Immune response · Immunization · Immunomodulation · Lactobacillus plantarum · Mouse · Nonhuman · T lymphocyte · Animals · Antigens, Dermatophagoides · Cells, Cultured · Dust · Female · Glycoproteins · Hypersensitivity, Immediate · Immunoglobulin E · Immunoglobulin G · Interferon Type II · Interleukin-5 · Lactobacillus · Lymphocyte Activation · Mice · Mice, Inbred C57BL · Mites · Recombinant Fusion Proteins · T-Lymphocytes · Th1 Cells · Th2 Cells · Transformation, Bacterial
[Abstract]

20 Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi α-subunits
article 2004    
Author: Klaasse, E. · Ligt, R.A.F.de · Roerink, S.F. · Lorenzen, A. · Milligan, G. · Leurs, R. · IJzerman, A.P.
Keywords: Health · Physiological Sciences · Adenosine A1 receptor · Allosteric modulation · Constitutive activity · Fusion protein · G protein · Inverse agonism · 2 amino 4,5 dimethyl 3 (3 trifluoromethylbenzoyl)thiophene · 6 n cyclopentyladenosine · 8 cyclopentyl 1,3 dipropylxanthine · 8 cyclopentyltheophylline · Adenosine A1 receptor · Amino acid · Arginine · Cysteine · Glycine · Guanine nucleotide binding protein · Guanosine 5' o (3 thiotriphosphate) · Histidine · Hybrid protein · Isoleucine · Phenylalanine · Proline · Radioligand · Serine · Sodium ion · Sulfur 35 · Valine · Allosterism · Alpha chain · Animal cell · Cercopithecidae · Ligand binding · Nonhuman · Priority journal · Protein analysis · Adenosine · Allosteric Site · Animals · Binding, Competitive · Cell Membrane · COS Cells · Cysteine · Dose-Response Relationship, Drug · GTP-Binding Protein alpha Subunits, Gi-Go · Guanosine 5'-O-(3-Thiotriphosphate) · Humans · Mutation · Radioligand Assay · Receptor, Adenosine A1 · Recombinant Fusion Proteins · Sodium Chloride · Sulfur Radioisotopes · Thiophenes · Transfection · Tritium · Xanthines
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 23 found. Next | Sort by date