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1 On the development of behavioral tolerance to organophosphates IV: EEG and visual evoked responses
article 1991    
Author: Wolthuis, O.L. · Philippens, I.H.C.H.M. · Vanwersch, R.A.P.
Keywords: Vision · DFP · EEG · Organophosphates · Soman · Tolerance · VER · Dyflos · Soman · Animal experiment · Behavior · Controlled study · Drug tolerance · Electric shock · Electroencephalogram · Evoked visual response · Male · Nonhuman · Pupil · RatS · Rectum temperature · Animal · Behavior, Animal · Body Temperature · Conditioning, Operant · Drug Tolerance · Electroencephalography · Electroshock · Evoked Potentials, Visual · Isoflurophate · Male · Organophosphorus Compounds · Rats, Inbred Strains · Isoflurophate, 55-91-4 · Organophosphorus Compounds · Soman, 96-64-0
[Abstract]

2 Semi-continuous high speed gas analysis of generated vapors of chemical warfare agents
article 1999    
Author: Trap, H.C. · Langenberg, J.P.
Keywords: Automation · Data acquisition · Nerve agents · Sulfur mustard · Valve injection · Vapor analysis · Mustard gas · Nerve gas · Neurotoxin · Sarin · Soman · Analytic method · Animal experiment · Article · Autoanalysis · Chemical warfare · Chromatography · Gas analysis · Gas chromatography · Guinea pig · Neurotoxicity · Nonhuman · Toxicokinetics · Vapor · Mustard gas, 505-60-2 · Neurotoxin, 39386-17-9 · Sarin, 107-44-8 · Soman, 96-64-0
[Abstract]

3 Low level nose-only exposure to the nerve agent soman: Toxicokinetics of soman stereoisomers and cholinesterase inhibition in atropinized guinea pigs
article 1998    
Author: Benschop, H.P. · Trap, H.C. · Spruit, H.E.T. · Wiel, H.J. van der · Langenberg, J.P. · Jong, L.P.A. de
Keywords: Perception · Atropine · Carboxylesterase · Cholinesterase · Animal cell · Blood level · Enzyme inhibition · Exposure · Guinea pig · Inhalation · Male · Neurotoxicity · Nonhuman · Stereoisomerism · Toxicokinetics · Administration, Inhalation · Animals · Carboxylic ester hydrolases · Chemical warfare agents · Dose-response relationship · Drugs · Erythrocytes · Soman · Stereoisomerism · Time factors · Atropine, 51-55-8 · Carboxylesterase, EC 3.1.1.1 · Carboxylic ester hydrolases, EC 3.1.1.- · Soman, 96-64-0
[Abstract]

4 The bispyridinium-dioxime HLö-7. A potent reactivator for acetylcholinesterase inhibited by the stereoisomers of tabun and soman
article 1989    
Author: Jong, L.P.A.de · Verhagen, M.A.A. · Langenberg, J.P. · Hagedorn, I. · Löffler, M.
Keywords: Biology · Bis(pyridinium oxime) derivative · Enzyme inhibitor · Organophosphorus compound · Radioisotope · Enzyme reactivation · Fish · Human · Nonbiological model · Nonhuman · Normal human · Rat · Stereoisomerism · Acetylcholinesterase 9000-81-1 · Animal · Cholinesterase Reactivators · Eels · Human · In Vitro · Organophosphorus Compounds · Oximes · Phosphoric Acid Esters · Pyridines · Pyridinium Compounds · Stereoisomerism · Structure-Activity Relationship · Organophosphorus compounds · Oximes · Phosphoric acid esters · Pyridines · Pyridinium compounds · Soman, 96-64-0 · Tabun, 77-81-6
[Abstract]

5 Capillary gas chromatographic analysis of nerve agents using large volume injections
article 1996    
Author: Degenhardt, C.E.A.M. · Kientz, C.E.
Keywords: Biology · GC - Gas chromatography · Nerve agents · Capillarity · Phosphorus organic compounds · GB agent · Military chemical agents · Cholinesterase Inhibitors · Isoflurophate, 55-91-4 · Organophosphorus compounds · Organothiophosphorus compounds · Sarin, 107-44-8 · Soman, 96-64-0 · VX, 50782-69-9 · Water, 7732-18-5 · Chemical warfare agents · DFP · Large volume injection · Organophosphorus compounds · Tabun · Dflos · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester · Capillary gas chromatography · Drug determination · Nonhuman · Sample · Technique · Water analysis · Water pollution · Cholinesterase Inhibitors · Chromatography, Gas · Hydrogen-Ion Concentration
[Abstract]

6 Exploring the active center of human acetylcholinesterase with stereomers of an organophosphorus inhibitor with two chiral centers
article 1999    
Author: Ordentlich, A. · Barak, D. · Kronman, C. · Benschop, H.P. · Jong, L.P.A. de · Ariel, N. · Barak, R. · Segall, Y. · Velan, B. · Shafferman, A.
Keywords: Cholinesterase reactivator · Soman · Binding site · Chirality · Dealkylation · Enzyme activity · Enzyme analysis · Enzyme binding · Enzyme specificity · Enzyme structure · Enzyme substrate · Human cell · Protein expression · Stereochemistry · Stereoisomerism · Alkylation · Amino acid substitution · Binding sites · Cell line · Cholinesterase inhibitors · Humans · Hydrogen Bonding · Kidney · Macromolecular substances · Models, Molecular · Mutagenesis, Site-Directed · Stereoisomerism · Acetylcholinesterase, EC 3.1.1.7 · Alanine, 56-41-7 · Phenylalanine, 63-91-2 · Phosphorus, 7723-14-0 · Soman, 96-64-0
[Abstract]

7 Improvements of the fluoride reactivation method for the verification of nerve agent exposure
article 2004    
Author: Degenhardt, C.E.A.M. · Pleijsier, K. · Schans, M.J. van der · Langenberg, J.P. · Preston, K.E. · Solano, M.I. · Maggio, V.L. · Barr, J.R.
Keywords: Warfare · Biological marker · Cholinesterase · Cyclosarin · Organophosphorus compound · Potassium fluoride · Sarin · Soman · Tabun · Unclassified drug · Calibration · Chemical analysis · Chemical warfare · Enzyme activity · Gas chromatography · Human · Mass spectrometry · Methodology · Neurotoxicity · Plasma · Solid phase extraction · Biological Markers · Butyrylcholinesterase · Chemical warfare agents · Cholinesterase reactivators · Environmental exposure · Environmental monitoring · Erythrocytes · Fluorides · Gas Chromatography-Mass Spectrometry · Humans · Reproducibility of results · Sensitivity and specificity · Cholinesterase, 9001-08-5 · Cyclosarin, 329-99-7 · Potassium fluoride, 7789-23-3 · Sarin, 107-44-8 · Soman, 96-64-0 · Tabun, 77-81-6 · Biological Markers · Butyrylcholinesterase, EC 3.1.1.- · Chemical Warfare Agents · Cholinesterase reactivators · Fluorides
[Abstract]

8 A physiologically based pharmacokinetic (PB/PK) model for multiple exposure routes for soman in multiple species
article 2006    
Author: Sweeney, R.E. · Langenberg, J.P. · Maxwell, D.M.
Keywords: Toxicology · Acetylcholinesterase · Carboxylesterase · Enzyme · Soman · Adipose tissue · Allometry · Animal experiment · Animal tissue · Arterial blood · Blood flow velocity · BLood level · Body weight · Breathing rate · Computer language · Computer simulation · Controlled study · Exposure · Guinea pig · In vitro study · Kidney perfusion · LD 50 · Liver perfusion · Lung perfusion · Male · Marmoset · Metabolism · Nonhuman · Partition coefficient · Priority journal · Provocation test · Rat · Regression analysis · Sensitivity analysis · Stereoisomerism · Tidal volume · Tissue level · Toxicokinetics · Venous blood · Administration, Inhalation · Animals · Callithrix · Chemical Warfare Agents · Cholinesterase Inhibitors · Computer Simulation · Guinea Pigs · Injections, Intravenous · Injections, Subcutaneous · Male · Models, Biological · Rats · Rats, Wistar · Animalia · Cavia porcellus · Marmosets · Acetylcholinesterase, 9000-81-1 · Carboxylesterase, 59536-71-9, 83380-83-0, 9016-18-6, 9028-01-7 · Soman, 96-64-0 · Chemical warfare agents · Cholinesterase inhibitors
[Abstract]

9 Retrospective detection of exposure to nerve agents: Analysis of phosphofluoridates originating from fluoride-induced rectivation of phospylated BuChE
article 2004    
Author: Schans, M.J. van der · Polhuijs, M. · Dijk, C. van · Degenhardt, C.E.A.M. · Pleijsier, K. · Langenberg, J.P. · Benschop, H.P.
Keywords: Biology · Biomarker · Biomonitoring · Butyryl cholinesterase · Fluoride ions · Lexposure · Nerve agents · Organophosphates · Reactivation · Retrospective detection · Cholinesterase · Cholinesterase inhibitor · Cyclosarin · Fluoride · Nerve gas · Organophosphate · Paraoxon · Parathion · Phosphorus derivative · Sarin · Soman · Tabun · Unclassified drug · Biological monitoring · Biological warfare · Chemical structure · Concentration (parameters) · Environmental exposure · Enzyme activation · Enzyme active site · Enzyme inhibition · Gas chromatography · Half life time · Human · Nonhuman · pH · Priority journal · Retrospective study · Rhesus monkey · Animals · Butyrylcholinesterase · Chemical Warfare Agents · Cholinesterase Inhibitors · Cholinesterase Reactivators · Gas chromatography · Female · Fluorides · Half-Life · Humans · Injections, Intravenous · Macaca mulatta · Male · Organophosphorus compounds · Paraoxon · Reference standards · Time factors · Macaca mulatta · Cholinesterase, 9001-08-5 · Cyclosarin, 329-99-7 · Fluoride, 16984-48-8 · Paraoxon, 311-45-5 · Parathion, 3270-86-8, 56-38-2, 597-88-6 · Sarin, 107-44-8 · Soman, 96-64-0 · Tabun, 77-81-6 · Butyrylcholinesterase, EC 3.1.1.- · Chemical warfare agents · Cholinesterase inhibitors · Cholinesterase reactivators · Fluorides · Organophosphorus compounds
[Abstract]

10 Toxicokinetics of the nerve agent (±)-VX in anesthetized and atropinized hairless guinea pigs and marmosets after intravenous and percutaneous administration
article 2003    
Author: Schans, M.J. van der · Lander, B.J. · Wiel, H. van der · Langenberg, J.P. · Benschop, H.P.
Keywords: Biology · Chiral HPLC · Hairless guinea pigs · Intravenous · Marmosets · Percutaneous · Persistence · Stereospecificity · Toxicokinetics · Treatment · Carbamic acid · Oxime · Volatile agent · Anesthesia · Animal experiment · Animal model · Bioavailability · Blood level · Dose response · Enantiomer · Guinea pig · Intoxication · Marmoset · Nonhuman · Primate · Toxicokinetics · Administration, Topical · Anesthesia · Animals · Atropine · Callithrix · Chemical Warfare Agents · Chromatography, Gas · Chromatography, High Pressure Liquid · Electrochemistry · Injections, Intravenous · Kinetics · Lethal Dose 50 · Male · Muscarinic Antagonists · Organothiophosphorus Compounds · Stereoisomerism · Animalia · Cavia · Cavia porcellus · Primates · Sus scrofa · Acetylcholinesterase, 9000-81-1 · Carbamic acid, 463-77-4 · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester, 50782-69-9 · Sarin, 107-44-8 · Soman, 96-64-0 · Acetylcholinesterase, EC 3.1.1.7 · Atropine, 51-55-8 · Chemical warfare agents · Muscarinic antagonists · Organothiophosphorus compounds · VX, 50782-69-9
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 10 of 10 found. | Sort by date