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1 Bile acids exert negative feedback control on bile acid synthesis in cultured pig hepatocytes by suppression of cholesterol 7α-hydroxylase activity
article 1990    
Author: Kwekkeboom, J. · Princen, H.M.G. · Voorthuizen, E.M. van · Kempen, H.J.M.
Keywords: Biology · Animal · Bile Acids and Salts · Cells, Cultured · Cholesterol 7-alpha-Hydroxylase · Feedback · Hydroxycholesterols · Liver · Swine · Taurocholic Acid
[Abstract]

2 Comparison of taurocholate accumulation in cultured hepatocytes of pig, rat and man
article 1989    
Author: Kwekkeboom, J. · Princen, H.M.G. · Voorthuizen, E.M. van · Meijer, P. · Kempen, H.J.M.
Keywords: Health · radioisotope · taurocholic acid · animal cell · cell culture · cell level · human cell · liver cell · nonhuman · Animal · Cells, Cultured · Comparative Study · Dexamethasone · Female · Human · Kinetics · Liver · Male · Rats · Rats, Inbred Strains · Species Specificity · Support, Non-U.S. Gov't · Swine · Taurocholic Acid · Vitamin E
[Abstract]

3 Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes
article 1995    
Author: Twisk, J. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Biology · bile acid · chenodeoxycholic acid · cholesterol 7alpha monooxygenase · cholic acid · deoxycholic acid · lithocholic acid · messenger rna · oxygenase · sterol · taurocholic acid · animal cell · article · bile acid synthesis · cholesterol metabolism · controlled study · enzyme inhibition · gene repression · liver cell culture · nonhuman · priority journal · rat · transcription regulation · Adenosine Triphosphate · Animal · Bile Acids and Salts · Cells, Cultured · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Down-Regulation · Gene Expression Regulation, Enzymologic · Liver · Male · Mitochondria · Oxidoreductases · Rats · Rats, Wistar · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Taurocholic Acid · Transcription, Genetic
[Abstract]

4 Bile acids and lipids in isolated rat hepatocytes. II. Source of cholesterol used for bile acid formation, estimated by incorporation of tritium from tritiated water, and by the effect of ML-236B
article 1983    
Author: Kempen, H.J. · Vos Van Holstein, M. · Lange, J.de
Keywords: Biology · Bile acid · Cholic acid · Compactin · Ml 236 b · Radioisotope · Tritium oxide · Unclassified drug · Animal cell · Beta muricholic acid · Cholesterol c 14 · Cholesterol h 3 · Cholesterol synthesis · Dihydroxycholanoic acid · In vitro study · Liver cell · Muricholic acid · Nonhuman · Taurocholic acid c 14 · Animal · Bile Acids and Salts · Cholesterol · Cholestyramine · Lipids · Liver · Naphthalenes · Rats · Tritium
[PDF] [Abstract]

5 Novel non-systemic inhibitor of ileal apical Na+-dependent bile acid transporter reduces serum cholesterol levels in hamsters and monkeys
article 2006    
Author: Kitayama, K. · Nakai, D. · Kono, K. · Hoop, A.G. van der · Kurata, H. · Wit, E.C. de · Cohen, L.H. · Inaba, T. · Kohama, T.
Keywords: Biology · Apical sodium-dependent bile acid transporter · Cholesterol · Enterohepatic circulation · Hamster · Hypocholesterolemic agent · Monkey · Carbon 14 · Cholesterol · High density lipoprotein cholesterol · Ileum apical bile acid transporter inhibitor · Phospholipid · Piperidine derivative · R 146224 · Taurocholic acid · Triacylglycerol · Tritium · Unclassified drug · Bile acid · Carrier protein · Cotransporter · Organic anion transporter · Quinoline derivative · Sodium · Sodium bile acid cotransporter · Sodium-bile acid cotransporter · Absorption · Animal experiment · Animal tissue · Bile duct fistula · Bile flow · Cholesterol blood level · Cholesterol esterification · Concentration response · Controlled study · Diet · Dose response · Drug mechanism · Embryo · Feeding · Human cell · Hypercholesterolemia · Hypolipemia · Inhibition kinetics · Time · Triacylglycerol blood level · Urinary excretion · Biosynthesis · Blood · Cell line · Drug antagonism · Drug effect · Genetics · In vitro study · Macaca · Metabolism · Physiology · Sprague Dawley rat · Syrian hamster · Animals · Anticholesteremic Agents · Bile Acids and Salts · Cell Line · Cholesterol · Cricetinae · Humans · Ileum · Macaca fascicularis · Male · Membrane Transport Proteins · Mesocricetus · Organic Anion Transporters, Sodium-Dependent · Piperidines · Quinolines · Rats · Rats, Sprague-Dawley · Sodium · Symporters · Taurocholic Acid
[Abstract]

6 Differential feedback regulation of cholesterol 7α-hydroxylase mRNA and transcriptional activity by rat bile acids in primary monolayer cultures of rat hepatocytes
article 1993    
Author: Twisk, J. · Lehmann, E.M. · Princen, H.M.G.
Keywords: Health · bile acid · chenodeoxycholic acid · cholesterol 7alpha monooxygenase · deoxycholic acid · glycocholic acid · messenger rna · animal cell · bile acid synthesis · controlled study · culture medium · dose time effect relation · down regulation · enzyme activity · enzyme regulation · feedback system · gene expression regulation · gene repression · genetic transcription · hydrophobicity · kinetics · liver cell · liver cell culture · monolayer culture · negative feedback · nonhuman · transcription regulation · Animal · Base Sequence · Bile Acids and Salts · Cells, Cultured · Chenodeoxycholic Acid · Cholesterol 7-alpha-Hydroxylase · Cholic Acid · Cholic Acids · Feedback · Gene Expression Regulation · Glycocholic Acid · Kinetics · Liver · Male · Molecular Sequence Data · Rats · RNA, Messenger · Support, Non-U.S. Gov't · Taurocholic Acid · Transcription, Genetic
[Abstract]

7 Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3
article 2014    
Author: Gozalpour, E. · Greupink, R. · Wortelboer, H.M. · Bilos, A. · Schreurs, M. · Russel, F.G.M. · Koenderink, J.B.
Keywords: Biology Pharmacology · Bufadienolides · Cardenolides · Cell transport · Convallatoxin · Digitalis-like compounds · Dihydroouabain · Drug-induced toxicity · NTCP · OATP1B1 · OATP1B3 · Ouabagenin · Ouabain · Cardiac glycoside · Convallatoxin · Cymarin · Dehydroouabain · Digitoxigenin · Digitoxin · Digoxigenin · Digoxin · Dihydroouabain · Estradiol 17 glucuronide · Gitoxigenin · Hydroxyl group · Ouabagenin · Ouabain · Peruvoside · Plant glycoside · Proscillaridin · Sodium bile acid cotransporter · Solute carrier organic anion transporter 1B1 · Solute carrier organic anion transporter 1B3 · Strophanthidin · Strophanthidol · Sugar · Taurocholic acid · Unclassified drug · Animal cell · Chemical structure · CHO cell line · Controlled study · Drug interaction · Drug uptake · Embryo · Human · Human cell · IC 50 · Kidney cell · Liquid chromatography · Mass spectrometry · Nonhuman · Food and Nutrition · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

8 Determinants of postprandial plasma bile acid kinetics in human volunteers
article 2017    
Author: Fiamoncini, J. · Yiorkas, A.M. · Gedrich, K. · Rundle, M. · Alsters, S.I. · Roeselers, G. · Broek, T.J. van den · Clavel, T. · Lagkouvardos, I. · Wopereis, S. · Frost, G. · Ommen, B. van · Blakemore, A.I. · Daniel, H.
Keywords: Biology · Bile acids · Mixed-meal tolerance test · Oral glucose tolerance test · Postprandial · SLCO1A2 · Chenodeoxycholic acid · Cholic acid · Deoxycholic acid · Genomic DNA · Glycine · Glycochenodeoxycholic acid · Glycocholic acid · Glycodeoxycholic acid · Glycoursodeoxycholic acid · Solute carrier organic anion transporter 1A2 · Taurine · Taurochenodeoxycholic acid · Taurocholic acid · Taurodeoxycholic acid · Taurolitocholic acid · Tauroursodeoxycholic acid · Unclassified drug · Ursodeoxycholic acid · Bile acid blood level · Bile acid synthesis · Clinical trial · Diet restriction · Dietary intake · Enterohepatic circulation · Feces microflora · Gene expression · Genome analysis · Kinetics · Liquid chromatography-mass spectrometry · Oral glucose tolerance test · Phenotype · Postprandial state · Quantitative analysis · Sex difference · Weight reduction · Whole exome sequencing · Blood · Controlled study · Physiology · Randomized controlled trial · Bile Acids and Salts · Fasting · Female · Humans · Male · Metabolic Clearance Rate · Middle Aged · Postprandial Period · Weight Loss · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 8 of 8 found. | Sort by date