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1 The hypothalamus-pituitary-testis axis in boys during the first six months of life: A comparison of cryptorchidism and hypospadias cases with controls
article 2009    
Author: Pierik, F.H. · Deddens, J.A. · Burdorf, A. · Keizer-Schrama, S.M.P.F.D.M. · Jong, F.H.D. · Weber, R.F.A.
Keywords: Health · AHM · Cryptorchidism · FSH · Hypospadias · Inhibin B · LH · Newborn boys · Testosterone · Built environment
[PDF] [Abstract]

2 Adenocarcinomas of the prostate induced by n-nitroso-n-methylurea in rats pretreated with cyproterone acetate and testosterone
article 1983    
Author: Bosland, M.C. · Prinsen, M.K. · Kroes, R.
Keywords: Cyproterone acetate · Methylnitrosourea · Testosterone · Testosterone propionate · Animal experiment · Chemical carcinogenesis · Male genital system · Nonhuman · Prostate cancer · Rat · Adenocarcinoma · Animal · Carcinoma in Situ · Cocarcinogenesis · Cyproterone · Cyproterone Acetate · Male · Methylnitrosourea · Models, Biological · Neoplasm Metastasis · Neoplasms, Experimental · Nitrosourea Compounds · Prostatic Neoplasms · Rats · Rats, Inbred Strains · Support, Non-U.S. Gov't · Testosterone
[Abstract]

3 Human cytochrome P450 enzyme selectivities in the oxidation of chlorinated benzenes
article 1995    
Author: Bogaards, J.J.P. · Ommen, B. van · Wolf, C.R. · Bladeren, P.J. van
Keywords: Toxicology · Cell Line · Chlorobenzenes · Chlorzoxazone · Chromatography, Gas · Cytochrome P-450 Enzyme System · Ethanolamines · Human · Oxazines · Oxidation-Reduction · Substrate Specificity · Testosterone · Transfection
[Abstract]

4 Assessment of some critical factors in the freezing technique for the cryopreservation of precision-cut rat liver slices
article 2000    
Author: Maas, W.J.M. · Graaf, I.A.M. de · Schoen, E.D. · Koster, H.J. · Sandt, J.J.M. van de · Groten, J.P.
Keywords: Production · Technology · Food · Adenosine triphosphate · Cryoprotective agent · Glutathione · Lactate dehydrogenase · Potassium · Testosterone · Animal tissue · Cell death · Cell metabolism · Cell viability · Controlled study · Cryopreservation · Enzyme activity · Freezing · Liver preservation · Male · Nonhuman · Priority journal · Protein content · Rat · Technique · Adenosine Triphosphate · Animals · Cryopreservation · Dinitrochlorobenzene · Evaluation Studies · Glutathione · Glutathione Transferase · L-Lactate Dehydrogenase · Liver · Male · Microtomy · Potassium · Proteins · Rats · Rats, Wistar · Testosterone · Tissue Preservation · Urea · Animalia
[Abstract]

5 Effect of moderate alcohol consumption on plasma dehydroepiandrosterone sulfate, testosterone, and estradiol levels in middle-aged men and postmenopausal women: A diet-controlled intervention study
article 2004    
Author: Sierksma, A. · Sarkola, T. · Eriksson, C.J.P. · Gaag, M.S. van der · Grobbee, D.E. · Hendriks, H.F.J.
Keywords: Health · Physiological Sciences · Alcohol · Dehydroepiandosterone Sulfate (DHEAS) · Estradiol · HDL Cholesterol · Testosterone · alcohol · amstel bier · amstel malt bier · estradiol · high density lipoprotein cholesterol · prasterone sulfate · testosterone · adult · alcohol consumption · alcoholic beverage · article · beer · blood sampling · body weight · cardiovascular disease · clinical article · clinical trial · confidence interval · controlled clinical trial · controlled study · correlation analysis · crossover procedure · diet restriction · dietary intake · disease association · female · heart protection · hormone blood level · human · male · postmenopause · priority journal · randomization · randomized controlled trial · Alcohol Drinking · Beer · Confidence Intervals · Cross-Over Studies · Dehydroepiandrosterone Sulfate · Diet · Estradiol · Female · Humans · Linear Models · Lipoproteins, HDL · Male · Middle Aged · Postmenopause · Testosterone
[Abstract]

6 Criteria to distinguish between natural situations and illegal use of boldenone, boldenone esters and boldione in cattle. 1. Metabolite profiles of boldenone, boldenone esters and boldione in cattle urine
article 2006    
Author: Le Bizec, B. · Courant, F. · Gaudin, I. · Bichon, E. · Destrez, B. · Schilt, R. · Draisci, R. · Monteau, F. · André, F.
Keywords: Biology · Analytical research · Anabolic · Boldenone · Endogenous · 17 Beta boldenone · Biological marker · Boldione · Drug metabolite · Unclassified drug · Animal experiments · Comparative study · Controlled study · Drug abuse · Drug metabolism · Drug urine level · Androstadienes · Cattle · Esters · Gas Chromatography-Mass Spectrometry · Testosterone · Animalia · Bos taurus
[Abstract]

7 Endocrine features of polycystic ovary syndrome in a random population sample of 14-16 year old adolescents
article 1999    
Author: Hooff, M.H.A. van · Voorhorst, F.J. · Kaptein, M.B.H. · Hirasing, R.A. · Koppenaal, C. · Schoemaker, J.
Keywords: Adolescents · Follicle stimulating hormone · Luteinizing hormone · Polycystic ovary syndrome · Adolescent · Amenorrhea · Androstenedione · Dehydroepiandrosterone Sulfate · Estradiol · Female · Follicle Stimulating Hormone · Humans · Logistic Models · Luteinizing Hormone · Oligomenorrhea · Polycystic Ovary Syndrome · Prolactin · Testosterone
[Abstract]

8 Presence and metabolism of the anabolic steroid boldenone in various animal species: A review
article 2004    
Author: Brabander, H.F. de · Poelmans, S. · Schilt, R. · Stephany, R.W. · Bizec, B. le · Draisci, R. · Sterk, S.S. · Ginkel, L.A. van · Courtheyn, D. · Hoof, N. van · Macrì, A. · Wasch, K. de
Keywords: Biology · Biotechnology · Anabolic steroids · Boldenone · Bovine · Calves · Endogenous · Illegal treatment · Metabolism · Phytosterol · 17alpha boldenone · 17beta boldenone · anabolic agent · boldenone · clostebol · illicit drug · nandrolone · stanozolol · testosterone · unclassified drug · analytic method · carcinogenicity · chemical structure · conjugation · controlled study · Crustacea · drug use · European Union · feces analysis · female · gas chromatography · human · laboratory test · liquid chromatography · male · mass spectrometry · medical research · microorganism · Mycobacterium · nonhuman · Phycomycetes · priority journal · review · screening test · species difference · steroid metabolism · urinary excretion · Anabolic Agents · Animals · Female · Humans · Male · Substance Abuse Detection · Testosterone · Animalia · Bovinae
[Abstract]

9 In vitro predictions of skin absorption of caffeine, testosterone, and benzoic acid: A multi-centre comparison study
article 2004    
Author: Sandt, J.J.M. van de · Burgsteden, J.A. van · Cage, S. · Carmichael, P.L. · Dick, I. · Kenyon, S. · Korinth, G. · Larese, F. · Limasset, J.C. · Maas, W.J.M. · Montomoli, L. · Nielsen, J.B. · Payan, J.-P. · Robinson, E. · Sartorelli, P. · Schaller, K.H. · Wilkinson, S.C. · Williams, F.M.
Keywords: Nutrition · Food and Chemical Risk Analysis · benzoic acid · caffeine · testosterone · adolescent · adult · aged · animal tissue · article · cell type · clinical protocol · controlled study · data analysis · diffusion · female · human · human tissue · laboratory test · lipophilicity · male · membrane · methodology · nonhuman · physical chemistry · priority journal · rat · skin absorption · skin penetration · skin test · skinfold thickness · toxicokinetics · Adolescent · Adult · Aged · Aged, 80 and over · Animals · Benzoic Acid · Cadaver · Caffeine · Diffusion Chambers, Culture · Europe · Female · Guideline Adherence · Humans · Laboratories · Male · Middle Aged · Rats · Reference Standards · Reproducibility of Results · Skin Absorption · Skinfold Thickness · Testosterone
[Abstract]

10 Identification of some important metabolites of boldenone in urine and feces of cattle by gas chromatography-mass spectrometry
article 1998    
Author: Puymbroeck, M. van · Kuilman, M.E.M. · Maas, R.F.M. · Witkamp, R.F. · Leyssens, L. · Zande, D.J.M. van der · Gelan, J. · Raus, J.
Keywords: Nutrition · Anabolic agent · Androstenedione · Boldenone · Drug metabolite · Animal tissue · Cattle · Conference paper · Drug feces level · Drug metabolism · Drug urine level · Gas chromatography · Liver cell · Liver microsome · Mass spectrometry · Nonhuman · Animals · Cells, Cultured · Feces · Gas Chromatography-Mass Spectrometry · Liver · Male · Microsomes, Liver · Testosterone
[PDF] [Abstract]

11 In vitro liver models are important tools to monitor the abuse of anabolic steroids in cattle
article 1998    
Author: Puymbroeck, M. van · Kuilman, M.E.M. · Maas, R.F.M. · Witkamp, R.F. · Leyssens, T. · Zande, D.J.M. van der · Gelan, J. · Raus, J.
Keywords: Nutrition · Anabolic agent · Biological marker · Boldenone · Clostebol · Estrane derivative · Ethylestrenol · Norethandrolone · Steroid · Animal tissue · Cattle · Conference paper · Controlled study · Drug abuse · Drug determination · Drug metabolism · Drug monitoring · Female · Liver · Liver cell culture · Liver metabolism · Liver microsome · Male · Model · Nonhuman · Steroid metabolism · Anabolic Agents · Animals · Biological Markers · Cattle · Cells, Cultured · Drug Residues · Estradiol · Ethylestrenol · Liver · Microsomes, Liver · Models, Biological · Norethandrolone · Predictive Value of Tests · Testosterone
[PDF] [Abstract]

12 Cryopreservation of precision-cut rat liver slices using a computer-controlled freezer
article 2000    
Author: Maas, W.J.M. · Leeman, W.R. · Groten, J.P. · Sandt, J.J.M. van de
Keywords: Computer-controlled freezing · Cryopreservation · Rat liver slices · Animal tissue · Computer · Controlled study · Cryopreservation · Dehydration · Liver slice · Nonhuman · Rat · Species difference · Technique · Thawing · Toxicity testing · Adenosine Triphosphate · Animal · Cell Separation · Cell Survival · Computer Systems · Cryopreservation · Dinitrochlorobenzene · Formazans · Freezing · Glutathione · Glutathione Transferase · Hepatocytes · Lactate Dehydrogenase · Liver · Male · Organ Preservation · Proteins · Rats · Rats, Wistar · Support, Non-U.S. Gov't · Testosterone · Tetrazolium Salts · Time Factors · Urea
[Abstract]

13 Insulin, androgen, and gonadotropin concentrations, body mass index, and waist to hip ratio in the first years after menarche in girls with regular menstrual cycles, irregular menstrual cycles, or oligomenorrhea
article 2000    
Author: Hooff, M.H.A. van · Voorhorst, F.J. · Kaptein, M.B.H. · Hirasing, R.A. · Koppenaal, C. · Schoemaker, J.
Keywords: Health · Luteinizing hormone · Prasterone sulfate · Prolactin · Body mass · Hormone blood level · Hyperandrogenism · Hyperinsulinemia · Major clinical study · Menstrual irregularity · Morphometrics · Adolescent · Androgens · Androstenedione · Body Constitution · Body Mass Index · Dehydroepiandrosterone Sulfate · Estradiol · Female · Gonadotropins, Pituitary · Humans · Insulin · Luteinizing Hormone · Menarche · Menstrual Cycle · Menstruation Disturbances · Oligomenorrhea · Reference Values · Testosterone
[Abstract]

14 Safety of long-term consumption of plant sterol esters-enriched spread
article 2003    
Author: Hendriks, H.F.J. · Brink, E.J. · Meijer, G.W. · Princen, H.M.G. · Ntanios, F.Y.
Keywords: Health Nutrition · Physiological Sciences · Cholesterol lowering · Coronary heart disease · Efficacy · Long-term study · Plant sterol esters · Safety · Spread · Alpha carotene · Beta carotene · Campesterol · Carotenoid · Cholesterol · Estradiol · Fatty acid ester · Follitropin · Low density lipoprotein cholesterol · Luteinizing hormone · Phytosterol · Progesterone · Sitosterol · Testosterone · Vitamin · Adult · Blood analysis · Cholesterol blood level · Clinical trial · Controlled clinical trial · Controlled study · Dietary intake · Double blind procedure · Eating habit · Erythrocyte deformability · Estradiol blood level · Female · Follitropin blood level · Human · Human experiment · Lifestyle · Lipid solubility · Lipoprotein blood level · Luteinizing hormone blood level · Male · Normal human · Nutrient concentration · Nutritional status · Outcomes research · Parallel design · Progesterone blood level · Randomized controlled trial · Testosterone blood level · Adult · Beta Carotene · Carotenoids · Cholesterol · Cholesterol, LDL · Diet · Dietary Fats · Double-Blind Method · Esters · Female · Humans · Male · Margarine · Middle Aged · Phytosterols · Placebos · Sitosterols
[Abstract]

15 Testosterone 15β-hydroxylation by solvent tolerant Pseudomonas putida S12
article 2007    
Author: Ruijssenaars, H.J. · Sperling, E.M.G.M. · Wiegerinck, P.H.G. · Brands, F.T.L. · Wery, J. · Bont, J.A.M.de
Keywords: Biology · Biotechnology · CYP106A2 · Fer · Pseudomonas putida · Solvent tolerance · Steroid synthesis · Whole cell biocatalyst · Biocatalysts · Enzyme kinetics · Hydroxylation · Optimization · Solvents · Pseudomonas putida · Solvent tolerance · Steroid synthesis · Whole cell biocatalysts · Drug products · 15 beta hydroxylase · bacterial protein · cytochrome P450 · organic solvent · steroid monooxygenase · testosterone · threonine · valine · 15beta hydroxylase CYP106A2, Bacillus megaterium · 15beta-hydroxylase CYP106A2, Bacillus megaterium · solvent · article · Bacillus subtilis · biocatalyst · biotransformation · chemical structure · controlled study · high performance liquid chromatography · nonhuman · nuclear magnetic resonance · priority journal · protein expression · Pseudomonas putida · steroid hydroxylation · steroidogenesis · biological model · enzyme specificity · evaluation · gene expression regulation · genetics · hydroxylation · metabolism · site directed mutagenesis · transgenic organism · Bacillus megaterium · Bacillus subtilis · Pseudomonas putida · Bacterial Proteins · Cytochrome P-450 Enzyme System · Gene Expression Regulation, Bacterial · Hydroxylation · Models, Biological · Mutagenesis, Site-Directed · Organisms, Genetically Modified · Pseudomonas putida · Solvents · Substrate Specificity · Testosterone
[Abstract]

16 Monolayers of IEC-18 cells as an in vitro model for screening the passive transcellular and paracellular transport across the intestinal barrier: Comparison of active and passive transport with the human colon carcinoma Caco-2 cell line
article 2002    
Author: Versantvoort, C.H.M. · Ondrewater, R.C.A. · Duizer, E. · Sandt, J.J.M. van de · Gilde, A.J. · Groten, J.P.
Keywords: Caco-2 · Carrier-mediated transport · H+-di/tripeptide carrier · IEC-18 · Intestinal cell lines · MRP · P-Glycoprotein · acetylsalicylic acid · calcein · carrier protein · dinitrophenylglutathione · glucose derivative · glutathione derivative · glycoprotein P · glycylsarcosine · hydrocortisone · macrogol 4000 · mannitol · methylglucose · multidrug resistance protein · probenecid · propranolol · rhodamine 123 · salicylic acid · testosterone · unclassified drug · verapamil · vincristine · animal cell · article · cell membrane permeability · cell strain CACO 2 · cell transport · colon carcinoma · controlled study · drug transport · human · human cell · in vitro study · ion transport · model · nonhuman · priority journal · protein expression · rat · screening
[Abstract]

17 Oral, but not transdermal, administration of estrogens lowers tissue- type plasminogen activator levels in humans without affecting endothelial synthesis
article 2000    
Author: Giltay, E.J. · Gooren, L.J.G. · Emeis, J.J. · Kooistra, T. · Stehouwer, C.D.A.
Keywords: Health · Endothelium · Sex hormones · Tissue-type plasminogen activator · Venous occlusion · Cyproterone acetate · Clinical trial · Controlled clinical trial · Controlled study · Drug effect · Endothelium · Enzyme analysis · Enzyme blood level · Enzyme metabolism · Enzyme synthesis · Fibrinolysis · Major clinical study · Randomized controlled trial · Vein occlusion · Administration, Cutaneous · Administration, Oral · Adult · Androgen Antagonists · Constriction · Cyproterone Acetate · Endothelium, Vascular · Estradiol · Estrogens · Ethinyl Estradiol · Female · Humans · Injections, Intramuscular · Male · Testosterone · Tissue Plasminogen Activator · Transsexualism · Veins
[Abstract]

18 Interactions of skin thickness and physicochemical properties of test compounds in percutaneous penetration studies
article 2006    
Author: Wilkinson, S.C. · Maas, W.J.M. · Nielsen, J.B. · Greaves, L.C. · Sandt, J.J.M. van de · Williams, F.M.
Keywords: Health · Biomedical Research · In vitro percutaneous penetration · Lipophilicity · OECD guideline 428 · 2 butoxyethanol · Alcohol · Caffeine · Propoxur · Water · Aqueous solution · Chemical analysis · Concentration (parameters) · Controlled study · Correlation analysis · Flow cytometry · Human cell · Human tissue · In vitro study · Lipophilicity · Liquid scintillation counting · Physical chemistry · Skin absorption · Skin penetration · Skin permeability · Skinfold thickness · Statistical analysis · Statistical significance · Validation process · 2,4-Dichlorophenoxyacetic Acid · Caffeine · Dose-Response Relationship, Drug · Europe · Humans · Propoxur · Skin Absorption · Skin Physiology · Testosterone
[Abstract]

19 Prediction of interindividual variation in drug plasma levels in vivo from individual enzyme kinetic data and physiologically based pharmacokinetic modeling
article 2000    
Author: Bogaards, J.J.P. · Hissink, E.M. · Briggs, M. · Weaver, R. · Jochemsen, R. · Jackson, P. · Bertrand, M. · Bladeren, P. van
Keywords: Nutrition · Cytochrome P450 · Interindividual variation · Metabolism · Physiologically based pharmacokinetic modeling · Agomelatine · Bufuralol · Chlorzoxazone · Coumarin · Cytochrome P450 · Diclofenac · Ethoxyresorufin · Mephenytoin · Testosterone · Clinical trial · Controlled clinical trial · Controlled study · Drug blood level · Enzyme kinetics · Food drug interaction · Genetic polymorphism · Human · Human cell · Human experiment · Human tissue · Liver microsome · Male · Model · Normal human · Phase 1 clinical trial · Phenotype · Priority journal · Acetamides · Cell Line · Cytochrome P-450 Enzyme System · Humans · Hypnotics and Sedatives · Isoenzymes · Kinetics · Microsomes, Liver · Models, Biological · Pharmaceutical Preparations · Pharmacokinetics · Recombinant Proteins · Transfection
[Abstract]

20 Characterization of adenocarcinomas of the dorsolateral prostate induced in Wistar rats by N-methyl-N-nitrosourea, 7,12-Dimethylbenz(a)anthracene, and 3,2'-Dimethyl-4-aminobiphenyl, following sequential treatment with cyproterone acetate and testosterone propionate
article 1990    
Author: Bosland, M.C. · Prinsen, M.K. · Dirksen, T.J.M. · Spit, B.J.
Keywords: cyproterone acetate · testosterone propionate · animal · animal cell · animal experiment · article · chemical carcinogenesis · histochemistry · histology · histopathology · intraperitoneal drug administration · mammal · nonhuman · oral drug administration · priority journal · prostate adenocarcinoma · prostate cancer · prostate carcinoma · 9,10-Dimethyl-1,2-benzanthracene · Acid Phosphatase · Adenocarcinoma · Aminobiphenyl Compounds · Animal · Carcinoma in Situ · Cell Differentiation · Histocytochemistry · Hyperplasia · Male · Methylnitrosourea · Microscopy, Electron · Neoplasm Metastasis · Precancerous Conditions · Prostatic Neoplasms · Rats · Support, Non-U.S. Gov't
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 29 found. Next | Sort by date