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Showing 1 to 20 of 24 found. Next | Sort by date

1 The spatial distribution of groundwater age for different geohydrological situations in the Netherlands: Implications for groundwater quality monitoring at the regional scale
article 2004    
Author: Broers, H.P.
Keywords: Geosciences · Groundwater age · Heterogeneity · Monitoring · Surficial drainage network · Tritium · Aquifers · Computer simulation · Contamination · Drainage · Groundwater pollution · Hydrogeology · Mathematical models · Groundwater recharge · Isochrones · Water table · Groundwater · dissolved matter · groundwater · hydrogeology · spatial distribution · tritium · water quality
[Abstract]

2 In vitro measurement of beta-carotene cleavage activity : methodological considerations and the effect of other carotenoids on beta-carotene cleavage
article 1996    
Author: Vliet, T. van · Schaik, F. van · Schreurs, W.H.P. · Berg, H. van den
Keywords: Nutrition · Animals · beta Carotene · beta-Carotene 15,15'-Monooxygenase · Carotenoids · Cricetinae · Cytosol · Female · Intestinal Mucosa · Intestine, Small · Male · Mesocricetus · Oxygenases · Rats · Rats, Wistar · Retinaldehyde · Tritium · Xanthophylls
[Abstract]

3 Bile acids and lipids in isolated rat hepatocytes. II. Source of cholesterol used for bile acid formation, estimated by incorporation of tritium from tritiated water, and by the effect of ML-236B
article 1983    
Author: Kempen, H.J. · Vos Van Holstein, M. · Lange, J.de
Keywords: Biology · Bile acid · Cholic acid · Compactin · Ml 236 b · Radioisotope · Tritium oxide · Unclassified drug · Animal cell · Beta muricholic acid · Cholesterol c 14 · Cholesterol h 3 · Cholesterol synthesis · Dihydroxycholanoic acid · In vitro study · Liver cell · Muricholic acid · Nonhuman · Taurocholic acid c 14 · Animal · Bile Acids and Salts · Cholesterol · Cholestyramine · Lipids · Liver · Naphthalenes · Rats · Tritium
[PDF] [Abstract]

4 Early increase of amino acid transport in stimulated lymphocytes
article 1971    
Author: Berg, K.J. van den · Betel, I.
Keywords: 2 amino 2 methylpropionic acid · active transport · drug effect · lymphocyte · male · metabolism · rat · time · tissue culture · Aminoisobutyric Acids · Animal · Biological Transport, Active · Carbon Isotopes · Lectins · Lymphocytes · Male · Rats · Thymidine · Time Factors · Tissue Culture · Tritium
[Abstract]

5 Dating degassed groundwater with 3H/3He
article 2007    
Author: Visser, A. · Broers, H.P. · Bierkens, M.F.P.
Keywords: Geosciences · Concentration (process) · Contamination · Denitrification · Nitrates · Degassing model · Isotopic fractionation · Groundwater · Concentration (process) · Contamination · Denitrification · Groundwater · Nitrates · agricultural runoff · dating method · degassing · denitrification · groundwater flow · groundwater pollution · helium isotope · isotopic fractionation · tritium · uncertainty analysis · Benelux · Eurasia · Europe · Netherlands · Western Europe
[Abstract]

6 Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver
article 1999    
Author: Mensenkamp, A.R. · Jong, M.C. · Goor, H. van · Luyn, M.J.A. van · Bloks, V. · Havinga, R. · Voshol, P.J. · Hofker, M.H. · Dijk, K.W. van · Havekes, L.M. · Kuipers, F.
Keywords: Biology · Animals · Apolipoproteins E · Cells, Cultured · Cholesterol · Crosses, Genetic · Fatty Acids, Nonesterified · Glycerol · Homeostasis · Humans · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Knockout · Mice, Transgenic · Microscopy, Immunoelectron · Phytosterols · Sitosterols · Sterols · Triglycerides · Tritium
[PDF] [Abstract]

7 1H-NMR spectroscopy combined with pattern recognition analysis reveals characteristic chemical patterns in urines of MS patients and non-human primates with MS-like disease
article 2003    
Author: Hart, B.A. 't · Vogels, J.T.W.E. · Spijksma, G. · Brok, H.P.M. · Polman, C. · Greef, J. van der
Keywords: Biology · Analytical research · Inflammatory demyelination · MS disease markers · NMR spectroscopy · Pattern recognition · Urine · myelin protein · organic compound · glycoprotein · tritium · animal model · article · autoimmune disease · chemical composition · clinical article · controlled study · disease course · encephalomyelitis · female · human · male · marmoset · molecular recognition · multiple sclerosis · multivariate analysis · nonhuman · primate · priority journal · proton nuclear magnetic resonance · urinalysis · validation process · allergic encephalomyelitis · animal · automated pattern recognition · chemistry · comparative study · disease model · immunization · immunology · methodology · nuclear magnetic resonance spectroscopy · species difference · time · urine · Animals · Callithrix · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Female · Glycoproteins · Humans · Immunization · Magnetic Resonance Spectroscopy · Male · Multiple Sclerosis · Multivariate Analysis · Myelin Proteins · Pattern Recognition, Automated · Species Specificity · Time Factors · Tritium · Urine
[Abstract]

8 Degassing of 3H/3He, CFCs and SF6 by denitrification: Measurements and two-phase transport simulations
article 2009    
Author: Visser, A. · Schaap, J.D. · Broers, H.P. · Bierkens, M.F.P.
Keywords: Geosciences · 3H/3He · CFCs · Degassing · Denitrification · Groundwater dating · SF6 · Two-phase transport modeling · Aquifers · Chlorofluorocarbons · Degassing · Denitrification · Fluid dynamics · Gas dynamics · Gases · Groundwater · Hydrogeology · Multiphase flow · Nitrification · Sulfur hexafluoride · Two phase flow · Underground reservoirs · H/He · CFCs · Groundwater dating · SF · Two-phase transport modeling · Helium · CFC · dating method · degassing · denitrification · hydrological modeling · measurement method · modeling · tracer · transport process · water table · chlorofluorocarbon · helium · nitrogen · sulfur hexafluoride · tritium · water · article · calibration · chemical model · chemistry · computer simulation · gas · isolation and purification · pressure · soil · Calibration · Chlorofluorocarbons · Computer Simulation · Gases · Helium · Models, Chemical · Nitrogen · Pressure · Soil · Sulfur Hexafluoride · Tritium · Water
[Abstract]

9 Comparison of selection methods to deduce natural background levels for groundwater units
article 2008    
Author: Griffioen, J. · Passier, H.F. · Klein, J.
Keywords: Geosciences · Contamination · Groundwater · Hydrogeology · Image segmentation · River pollution · Tritium · Underground reservoirs · Water quality · Agricultural contamination · Ground water quality · natural backgrounds · Netherlands · River Rhine · selection methods · Sub catchments · Groundwater pollution · ammonia · chloride · chlorine · ground water · nitrite · rain · sulfate · tritium · comparative study · groundwater pollution · nitrate · recharge · redox potential · water quality · agriculture · article · chemical composition · concentration (parameters) · geology · hydrodynamics · intermethod comparison · natural background level · Netherlands · oxidation reduction reaction · river · sampling · solute · water contamination · water quality · Chlorides · Environmental Monitoring · Fresh Water · Geology · Netherlands · Quaternary Ammonium Compounds · Sulfates · Water Pollutants, Chemical · Eurasia · Europe · Rhine River
[Abstract]

10 Hyperlipidaemia is associated with increased insulin-mediated glucose metabolism, reduced fatty acid metabolism and normal blood pressure in transgenic mice overexpressing human apolipoprotein C1
article 2001    
Author: Koopmans, S.J. · Jong, M.C. · Que, I. · Dahlmans, V.E.H. · Pijl, H. · Radder, J.K. · Frölich, M. · Havekes, L.M.
Keywords: Biology · APOC1 · Hypertension · Insulin resistance · Insulin resistance syndrome · Lipoprotein · NEFA · Fatty acid · Palmitic acid · Triacylglycerol · Tritium · Very low density lipoprotein · Adipose tissue · Animal model · Animal tissue · Blood pressure · Cholesterol blood level · Clearance · Controlled study · Fatty acid metabolism · Gene overexpression · Glucose blood level · Glucose clamp technique · Glucose metabolism · Glycogen synthesis · Glycolysis · Heart rate · Hyperinsulinemia · Hyperlipidemia · Hypertension · In vivo study · Infusion · Insulin resistance · Lipid transport · Lipogenesis · Mean arterial pressure · Mouse · Nonhuman · Skeletal muscle · Transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins C · Blood Glucose · Blood Pressure · Cholesterol · Fatty Acids, Nonesterified · Gene Expression · Glucose · Glucose Clamp Technique · Glycogen · Humans · Hyperlipidemias · Insulin · Lipid Metabolism · Liver · Mice · Mice, Transgenic · Muscle, Skeletal · Palmitic Acid · Triglycerides · Tritium
[Abstract]

11 Ritonavir impairs lipoprotein lipase-mediated lipolysis and decreases uptake of fatty acids in adipose tissue
article 2006    
Author: Boer, M.A.M. den · Berbée, J.F.P. · Reiss, P. · Valk, M. van der · Voshol, P.J. · Kuipers, F. · Havekes, L.M. · Rensen, P.C.N. · Romijn, J.A.
Keywords: Dyslipidemia · FA metabolism · Protease inhibitor · TG metabolism · Transgenic mice · Albumin · Lipoprotein lipase · Proteinase inhibitor · Ritonavir · Triacylglycerol · Triolein · Very low density lipoprotein · Anticoagulant agent · Apolipoprotein E · Apolipoprotein E3 (Leidein) · Diagnostic agent · Fatty acid · Heparin · Tritium · Very low density lipoprotein cholesterol · Adipose tissue · Animal tissue · Clearance · Controlled study · Drug mechanism · Emulsion · Enzyme activity · Fat intake · Fatty acid metabolism · Fatty acid transport · Half life time · Hypertriglyceridemia · Lipid diet · Lipodystrophy · Lipolysis · Mouse · Nonhuman · Postprandial state · Transgenic mouse · Triacylglycerol blood level · Biosynthesis · Blood · Chemically induced disorder · Drug effect · Enzyme activation · Genetics · Human immunodeficiency virus infection · Metabolism · Adipose Tissue · Animals · Anticoagulants · Apolipoprotein E3 · Apolipoproteins E · Cholesterol, VLDL · Emulsions · Enzyme Activation · Fatty Acids · Female · Heparin · HIV Infections · HIV Protease Inhibitors · Hypertriglyceridemia · Lipolysis · Lipoprotein Lipase · Mice · Mice, Transgenic · Postprandial Period · Ritonavir · Triglycerides · Triolein · Tritium
[Abstract]

12 Immunochemical study of DNA modifications in the nuclei of UV-damaged lymphocytes
article 2004    
Author: Snopov, S.A. · Gruijl, F.R. de · Roza, L. · Leun, J.C. van der
Keywords: Biology · Physiological Sciences · Cyclobutane derivative · Dimer · DNA fragment · Monoclonal antibody · Novobiocin · Pyrimidine derivative · Single stranded DNA · Tritium · Binding site · Cell labeling · Cell nucleus · Controlled study · Culture medium · DNA damage · DNA isolation · DNA modification · Excision repair · Flow cytometry · Fluorescence analysis · Human · Human cell · Immune response · Immunochemistry · Lymphocyte · Lymphocyte culture · Malignant transformation · Priority journal · Quantitative analysis · Skin cancer · Sun exposure · Temperature · Ultraviolet radiation · Cell Nucleus · Cells, Cultured · DNA · DNA Damage · Humans · Immunohistochemistry · Lymphocytes · Pyrimidine Dimers · Ultraviolet Rays
[Abstract]

13 Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis
article 2001    
Author: Ronday, H.K. · Laan, W.H. van der · Tak, P.P. · Roos, J.A.D.M. de · Bank, R.A. · Tekoppele, J.M. · Froelich, C.J. · Hack, C.E. · Hogendoorn, P.C.W. · Breedveld, F.C. · Verheijen, J.H.
Keywords: Biology Health · Biomedical Research · Cartilage destruction · Granzyme B · Rheumatoid arthritis · collagen · glycosaminoglycan · granzyme B · hydroxyproline · proline · proteoglycan · sulfate · sulfur 35 · tritium · animal tissue · bone erosion · cartilage degeneration · cartilage matrix · collagen degradation · controlled study · explant · human cell · immunohistochemistry · isotope labeling · joint destruction · nonhuman · priority journal · protein denaturation · protein expression · proteoglycan synthesis · rheumatoid arthritis · synovium · Animals · Arthritis, Rheumatoid · Cartilage · Cattle · Cells, Cultured · Chondrocytes · Collagen · Extracellular Matrix · Granzymes · Humans · Metacarpophalangeal Joint · Proteoglycans · Serine Endopeptidases · Synovial Membrane
[Abstract]

14 Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL
article 2005    
Author: Berbée, J.F.P. · Hoogt, C.C. van der · Sundararaman, D. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Apolipoprotein C-I · Fatty acids · Lipid metabolism · Lipoprotein lipase · Triglycerides · Very low density lipoprotein · Lipoprotein receptor · Tritium · Very low density lipoprotein · Animal experiment · Animal model · Cholesterol blood level · Controlled study · Enzyme activity · Half life time · Hyperlipidemia · Hyperlipoproteinemia type 3 · Lipolysis · Mouse · Nonhuman · Pathophysiology · Protein expression · Transgenic mouse · Animals · Apolipoproteins · Apolipoproteins C · Apolipoproteins E · Humans · Hypertriglyceridemia · Lactoferrin · Lipoproteins, VLDL · Liver · Mice · Mice, Inbred C57BL · Mice, Transgenic · Phenotype · Time Factors
[PDF] [Abstract]

15 Demonstrating trend reversal of groundwater quality in relation to time of recharge determined by 3H/3He
article 2007    
Author: Visser, A. · Broers, H.P. · Grift, B. van der · Bierkens, M.F.P.
Keywords: Geosciences · 3H/3He · Groundwater age · Groundwater quality · Monitoring · Nitrate · Trends · Agricultural wastes · Helium · Nitrates · Water pollution · Water quality · Groundwater age · Groundwater quality · Quality monitoring networks · Recharging (underground waters) · ground water · helium · helium 3 · nitrate · tritium · agricultural land · European Union · groundwater · groundwater pollution · helium isotope · hydrogen isotope · legislation · nitrate · pollution monitoring · recharge · water quality · water resource · age determination · agricultural waste · aquifer · article · European Union · law · Netherlands · trend study · water analysis · water contamination · water pollutant · water quality · water sampling · Benelux · Eurasia · Europe · Netherlands · Western Europe
[Abstract]

16 CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice
article 2003    
Author: Goudriaan, J.R. · Dahlmans, V.E.H. · Teusink, B. · Ouwens, D.M. · Febbraio, M. · Maassen, J.A. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Biology · Biomedical Research · Fatty acid transport · Glucose metabolism · Hepatic steatosis · Hyperinsulinemic clamp · CD36 antigen · fatty acid · glucose · protein kinase B · triacylglycerol · unclassified drug · animal experiment · animal model · animal tissue · controlled study · enzyme activation · enzyme deficiency · fatty acid blood level · glucose blood level · glucose transport · hyperinsulinemia · insulin sensitivity · male · mouse · muscle · nonhuman · spontaneously hypertensive rat · triacylglycerol blood level · Western blotting · wild type · Animals · Antigens, CD36 · Blood Glucose · Body Weight · Eating · Gene Deletion · Insulin · Insulin Resistance · Lipids · Liver · Mice · Mice, Inbred C57BL · Muscle, Skeletal · Rats · Signal Transduction · Triglycerides · Tritium
[PDF] [Abstract]

17 Comparison of in vitro assays in selecting radiotracers for in vivo P-glycoprotein PET imaging
article 2017    
Author: Raaphorst, R.M. · Savolainen, H. · Cantore, M. · Steeg, E. van de · Waarde, A. van · Colabufo, N.A. · Elsinga, P.H. · Lammertsma, A.A. · Windhorst, A.D. · Luurtsema, G.
Keywords: Biology · Apical and basolateral membrane · Bidirectional transport · Blood-brain barrier · Calcein-AM · Tritium labeling · Calcein · Mc 224 f 18 · Mc 225 f 18 · Multidrug resistance protein · N fluoroethylverapamil f 18 · O fluoroethyl norverapamil f 18 · Radiopharmaceutical agent · Unclassified drug · Verapamil c 11 · Animal experiment · Animal tissue · Chemical analysis · Controlled study · Drug accumulation · Drug blood level · Drug brain level · Drug half life · Enzyme inhibition · Fluoroethylation · In vitro study · In vivo study · Isotope labeling · Male · Mouse · Nonhuman · Positron emission tomography · Predictive value · Protein function · Radioactivity · Rat · Synthesis · Transport assay · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

18 Cyclopentyladenosine and some of its low-efficacy derivatives inhibit striatal synaptosomal release of acetylcholine to a similar degree
article 2003    
Author: Bueters, T.J.H. · Duivenvoorde, L.M. van · Danhof, M. · IJzerman, A.P. · Helden, H.P.M. van
Keywords: Biology · 3D-CPA (3′-deoxy-CPA) · 8-BCPA (8-butylamino-CPA) · 8-PCPA (8-propylamino-CPA) · Acetylcholine release · Adenosine A1 receptor · CPA (cyclopentyladenosine) · Low-efficacy agonist · Neuronal synaptosome · Partial agonist · 3' deoxy 6 n cyclopentyladenosine · 8 butylamino 6 n cyclopentyladenosine · 8 propylamino 6 n cyclopentyladenosine · Adenosine A2 receptor antagonist · Adenosine derivative · Adenosine receptor blocking agent · Partial agonist · Tritium · Unclassified drug · Animal tissue · Brain synaptosome · Cardiotoxicity · Concentration response · Controlled study · Corpus striatum · Drug effect · Evoked response · Inhibition kinetics · Male · Nonhuman · Rat · Adenosine · Animals · Dose-Response Relationship, Drug · Rats, Wistar · Synaptosomes · 4 aminopyridine, 1003-40-3, 504-24-5 · 5 amino 2 (2 furyl) 7 (2 phenylethyl)pyrazolo[4,3 e][1,2,4]triazolo[1,5 c]pyrimidine, 160098-96-4 · 6 n cyclopentyladenosine, 41552-82-3 · Acetylcholine, 51-84-3, 60-31-1, 66-23-9 · Theophylline, 58-55-9, 5967-84-0, 8055-07-0, 8061-56-1, 99007-19-9 · Tritium, 10028-17-8 · Adenosine, 58-61-7 · N(6)-cyclopentyladenosine, 41552-82-3
[Abstract]

19 PXR agonism decreases plasma HDL levels in ApoE*3-Leiden.CETP mice
article 2009    
Author: Haan, W. de · Vries-van der Weij, J. de · Mol, I.M. · Hoekstra, M. · Romijn, J.A. · Jukema, J.W. · Havekes, L.M. · Princen, H.M.G. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Cholesteryl ester transfer protein · Gene expression · High density lipoprotein · Pregnane X Receptor · Transgenic mice · Triglycerides · 5 pregnen 3beta ol 20 one 16alpha carbonitrile · ABC transporter A1 · apolipoprotein E3 · cholesterol · cholesterol ester transfer protein · cholesterol oleate · complementary DNA · high density lipoprotein · low density lipoprotein · messenger RNA · pregnane X receptor · pregnenolone derivative · triacylglycerol · tritium · unclassified drug · animal experiment · animal tissue · article · atherosclerosis · cholesterol blood level · controlled study · female · gene expression · lipid liver level · lipoprotein metabolism · mouse · nonhuman · plasma · polyacrylamide gel electrophoresis · priority journal · reverse transcription polymerase chain reaction · transgenic mouse · triacylglycerol blood level · Animals · Apolipoprotein E3 · ATP-Binding Cassette Transporters · Cholesterol Ester Transfer Proteins · Cholesterol, HDL · Female · Immunoblotting · Lipids · Lipoproteins · Liver · Mice · Mice, Transgenic · Pregnenolone Carbonitrile · Receptors, Steroid · RNA, Messenger · Scavenger Receptors, Class B · Mus · Mus musculus
[Abstract]

20 Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi α-subunits
article 2004    
Author: Klaasse, E. · Ligt, R.A.F.de · Roerink, S.F. · Lorenzen, A. · Milligan, G. · Leurs, R. · IJzerman, A.P.
Keywords: Health · Physiological Sciences · Adenosine A1 receptor · Allosteric modulation · Constitutive activity · Fusion protein · G protein · Inverse agonism · 2 amino 4,5 dimethyl 3 (3 trifluoromethylbenzoyl)thiophene · 6 n cyclopentyladenosine · 8 cyclopentyl 1,3 dipropylxanthine · 8 cyclopentyltheophylline · Adenosine A1 receptor · Amino acid · Arginine · Cysteine · Glycine · Guanine nucleotide binding protein · Guanosine 5' o (3 thiotriphosphate) · Histidine · Hybrid protein · Isoleucine · Phenylalanine · Proline · Radioligand · Serine · Sodium ion · Sulfur 35 · Valine · Allosterism · Alpha chain · Animal cell · Cercopithecidae · Ligand binding · Nonhuman · Priority journal · Protein analysis · Adenosine · Allosteric Site · Animals · Binding, Competitive · Cell Membrane · COS Cells · Cysteine · Dose-Response Relationship, Drug · GTP-Binding Protein alpha Subunits, Gi-Go · Guanosine 5'-O-(3-Thiotriphosphate) · Humans · Mutation · Radioligand Assay · Receptor, Adenosine A1 · Recombinant Fusion Proteins · Sodium Chloride · Sulfur Radioisotopes · Thiophenes · Transfection · Tritium · Xanthines
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 24 found. Next | Sort by date