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1 Optimisation of the post-validation process: The report and recommendations of ECVAM workshop 67
article 2008    
Author: Bottini, A.A. · Alepee, N. · Phillips, B. · Gribaldo, L. · Silva, O. de · Hartung, T. · Hendriksen, C. · Kuil, J. · Pazos, P. · Rhein, C. · Schiffelers, M.-J. · Stokes, W. · Theobald, A. · Vidal, J.-M. · Sandt, H. van de · Breier, S. · Sintes, J.R. · Blaauboer, B.
Keywords: Nutrition · Food and Chemical Risk Analysis · animal welfare · conference paper · health care policy · industry · law · medical research · priority journal · public health problem · skin test · validation process · Animal Testing Alternatives · Animals · Health Planning Guidelines · Validation Studies as Topic

2 The Draize Eye Test and in vitro alternatives; a left-handed marriage?
article 2006    
Author: Prinsen, M.K.
Keywords: Biology · Toxicology and Applied Pharmacology · Draize Eye Test · In vitro assay · Validation · article · draize eye test · exposure · in vitro study · nonhuman · solid · technique · validation process · Acute Toxicity Tests · Animal Testing Alternatives · Animals · Eye · Irritants · Rabbits · Reproducibility of Results

3 Spectrophotometric tool for the determination of the total carboxylate content in proteins; molar extinction coefficient of the enol ester from Woodward's reagent K reacted with protein carboxylates
article 2003    
Author: Kosters, H.A. · Jongh, H.H.J.de
Keywords: Nutrition · Food technology · Chemical modification · Chromatographic analysis · Degradation · Esters · pH effects · Spectrophotometry · Molar extinction · Proteins · chemical analysis · degradation · ion exchange chromatography · methylation · molecular stability · pH · protein modification · protein stability · reaction analysis · spectrophotometry · temperature dependence · validation process · Animals · Carboxylic Acids · Chickens · Esters · Isoxazoles · Kinetics · Ovalbumin · Proteins · Spectrophotometry, Ultraviolet
[Abstract]

4 Toxicology in the 21st century - Working our way towards a visionary reality
article 2011    
Author: Berg, N. · Wever, B.de · Fuchs, H.W. · Gaca, M. · Krul, C.A.M. · Roggen, E.L.
Keywords: Health · -Omics · 21st Century vision · 3Rs · Computational · In vitro · Replacement · Testing strategy · Toxicity testing · Validation · article · biological model · education · Europe · ex vivo study · financial management · in vitro study · in vivo study · interpersonal communication · leadership · medical research · practice guideline · risk assessment · standardization · systems biology · toxicity testing · toxicology · validation process · Animalia · Healthy living · Biomedical Innovations · Themalijn
[Abstract]

5 Balancing speech intelligibility versus sound exposure in selection of personal hearing protection equipment for Chinook aircrews
article 2001    
Author: Wijngaarden, S.J. van · Rots, G.
Keywords: aviation Acoustics and Audiology · Aircrews speech transmission index · Communication · Earplugs · Hearing protection · Noise exposure · Speech intelligibility · airplane crew · hearing impairment · long term exposure · performance · protective equipment · sound · speech intelligibility · validation process · Aerospace Medicine · Ear Protective Devices · Hearing Loss, Noise-Induced · Humans · Materials Testing · Occupational Diseases · Occupational Health · Speech Intelligibility
[Abstract]

6 Preliminary validation of real-time PCR assays for the identification of Yersinia pestis (Authors' personal document)
article 2008    
Author: Tomaso, H. · Jacobs, D. · Eickhoff, M. · Scholz, H.C. · Dahouk, S.al · Kattar, M.M. · Reischl, U. · Plicka, H. · Strand Olsen, J. · Nikkari, S. · Matero, P. · Beuret, C. · Ciammaruconi, A. · Lista, F. · Gala, J.-L. · Broll, H. · Appel, B. · Sellek Cano, R.E. · Ybarra de Villavicencio, M.d.C. · Broekhuijsen, M.P. · Indra, A. · Petersen, R. · Neubauer, H.
Keywords: Defence · Real-time PCR · Yersinia pestis · Article · Bacterium identification · Bacterium isolate · Controlled study · Diagnostic accuracy · Nonhuman · Nucleotide sequence · Priority journal · Real time polymerase chain reaction · Validation process · Yersinia pestis · Biological Warfare Agents · Laboratories · Polymerase Chain Reaction · Reproducibility of Results · Time Factors · Yersinia pestis · Bacteria (microorganisms) · Rodentia · Siphonaptera (fleas) · Yersinia pestis
[Abstract]

7 Carcinogenicity
article 2005    
Author: Maurici, D. · Aardema, M. · Corvi, R. · Kleber, M. · Krul, C.A.M. · Laurent, C. · Loprieno, N. · Pasanen, M. · Pfuhler, S. · Phillips, B. · Prentice, D. · Sabbioni, E. · Sanner, T. · Vanparys, P.
Keywords: Health · Biomedical Research · animal testing alternative · carcinogenesis · carcinogenicity · cell communication · cell culture · cell transformation · gap junction · genotoxicity · heterozygosity · nonhuman · priority journal · review · risk assessment · standardization · transgenic mouse · validation process · Animal Testing Alternatives · Animals · Carcinogenicity Tests · Carcinogens · Cell Transformation, Neoplastic · Cells, Cultured · Consumer Product Safety · Cosmetics · European Union · Gap Junctions · Mice · Mice, Transgenic · Quantitative Structure-Activity Relationship · Rats · Animalia · Mus musculus

8 Interlaboratory and interplatform comparison of microarray gene expression analysis of HepG2 cells exposed to benzo(a)pyrene
article 2009    
Author: Hockley, S.L. · Mathijs, K. · Staal, Y.C.M. · Brewer, D. · Giddings, I. · Delft, J.H.M. van · Phillips, D.H.
Keywords: Biology · Toxicology and Applied Pharmacology · benzo[a]pyrene · RNA · article · cell strain HepG2 · correlation analysis · data analysis · DNA microarray · false negative result · gene expression profiling · human · human cell · intermethod comparison · laboratory · microarray analysis · nucleotide sequence · principal component analysis · priority journal · quantitative assay · real time polymerase chain reaction · transcriptomics · validation process
[Abstract]

9 Forensic analysis of explosions: Inverse calculation of the charge mass
article 2015    
Author: Voort, M.M. van der · Wees, R.M.M. van · Brouwer, S.D. · Jagt-Deutekom, M.J. van der · Verreault, J.
Keywords: Explosives · Explosion · Forensic analysis · Blast · Debris · Damage · Statistical analysis · Blast · Damage · Debris · Explosion · Forensic analysis · Statistical analysis · Accuracy · Building · Computational fluid dynamics · Environmental exposure · Explosion · Explosion risk · Forensic identification · Mass disaster · Prediction · Process development · Reliability · Risk assessment · Statistical model · Urban area · Validation process · Mechanics, Materials and Structures · EBP - Explosions, Ballistics & Protection WS - Weapon Systems · TS - Technical Sciences
[Abstract]

10 Prediction of fruit and vegetable intake from biomarkers using individual participant data of diet-controlled intervention studies
article 2015    
Author: Souverein, O.W. · Vries, J.H.M. de · Freese, R. · Watzl, B. · Bub, A. · Miller, E.R., III · Castenmiller, J.J.M. · Pasman, W.J. · Hof, K. van het · Chopra, M. · Karlsen, A. · Dragsted, L.O. · Winkels, R. · Itsiopoulos, C. · Brazionis, L. · O'Dea, K. · Loo-Bouwman, C.A. van · Naber, T.H.J. · Voet, H. van der · Boshuizen, H.C.
Keywords: Health · Carotenoids · Folate · Fruits and vegetables · Prediction models · Vitamin C · Ascorbic acid · Beta carotene · Beta cryptoxanthin · Biological marker · Folic acid · Lycopene · Xanthophyll · Zeaxanthin · Age distribution · Body mass · Food intake · Fruit juice · Fruitarian diet · Prediction · Questionnaire · Sex difference · Smoking · Validation process · Vegetarian diet · Vitamin blood level · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

11 Establishment of a general NAFLD scoring system for rodent models and comparison to human liver pathology
article 2014    
Author: Liang, W. · Menke, A.L. · Driessen, A. · Koek, G.H. · Lindeman, J.H. · Stoop, R. · Havekes, L.M. · Kleemann., R. · Hoek, A.M. van den
Keywords: Biology · Adult · Animal experiment · Animal model · Clinical article · Controlled study · Female · Hepatitis · Histopathology · Human · Human tissue · Human versus animal comparison · Liver biopsy · Liver fibrosis · Liver hypertrophy · Macrovesicular steatosis · Male · Microvesicular steatosis · Nonalcoholic fatty liver · Nonhuman · Process development · Reproducibility · Scoring system · Steatosis · Validation process · Rodentia · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

12 Evaluation of migration models that might be used in support of regulations for food-contact plastics
article 2005    
Author: Begley, T. · Castle, L. · Feigenbaum, A. · Franz, R. · Hinrichs, K. · Lickly, T. · Mercea, P. · Milana, M. · O'Brien, A. · Rebre, S. · Rijk, R. · Piringer, O.
Keywords: Nutrition Packaging · Analytical research · Diffusion · Food-contact plastics · Migration · Modelling · Polyamide · Polyester · Polyolefin · Polystyrene · Food additive · Plastic · Confidence interval · Controlled study · Diffusion coefficient · Food contamination · Food control · Food processing · Food safety · Food storage · Mathematical model · Priority journal · Reliability · Validation process · Diffusion · European Union · Food Contamination · Food Industry · Food Packaging · Humans · Legislation, Food · Models, Chemical · Plastics
[Abstract]

13 Validated sampling strategy for assessing contaminants in soil stockpiles
article 2005    
Author: Lamé, F. · Honders, T. · Derksen, G.B. · Gadella, M.
Keywords: Biology · Mean concentration · Sampling strategy · Soil · Stockpile · Validation · Concentration (process) · Contamination · Impurities · Laws and legislation · Sampling · Degree of contamination · Heterogeneity · Sampling strategy · Soil stockpile · Soil mechanics · assessment method · sampling · soil pollution · article · automation · data base · Netherlands · randomization · sampling · soil analysis · theoretical study · validation process · Environmental Monitoring · Hazardous Waste · Humans · Lead · Soil Pollutants · Healthy for Life · Healthy Living
[Abstract]

14 Microbial metabolomics: Replacing trial-and-error by the unbiased selection and ranking of targets
article 2005    
Author: Werf, M.J. van der · Jellema, R.H. · Hankemeier, T.
Keywords: Nutrition · Biotechnology · Bioprocess optimization · Biostatistics · Holistic analysis · Metabolic engineering · Metabolomics · Multivariate statistics · Quenching · Strain improvement · accuracy · algorithm · analytic method · article · bioinformatics · bioprocess · biostatistics · data base · DNA modification · extraction · information processing · interstitial fluid · metabolic engineering · metabolite · metabolomics · microorganism · molecular weight · nonhuman · observer variation · reproducibility · separation technique · statistical analysis · strain difference · validation process · Bacteria · Computational Biology · Energy Metabolism · Genomics · Industrial Microbiology · Proteomics
[Abstract]

15 Toxicokinetics and metabolism
article 2005    
Author: Coecke, S. · Blaauboer, B.J. · Elaut, G. · Freeman, S. · Freidig, A. · Gensmantel, N. · Hoet, P. · Kapoulas, V.M. · Ladstetter, B. · Langley, G. · Leahy, D. · Mannens, G. · Meneguz, A. · Monshouwer, M. · Nemery, B. · Pelkonen, O. · Pfaller, W. · Prieto, P. · Proctor, N. · Rogiers, V. · Rostami-Hodjegan, A. · Sabbioni, E. · Steiling, W. · Sandt, J.J.M. van de
Keywords: Toxicology · Food and Chemical Risk Analysis · cosmetic · acute toxicity · artificial membrane · bioavailability · biotransformation · carcinogenicity · cell line · cell strain CACO 2 · computer model · concentration response · electric resistance · eye irritation · genotoxicity · human · metabolism · nonhuman · phototoxicity · plasma protein binding · practice guideline · priority journal · reproductive toxicity · review · skin absorption · skin sensitization · species difference · toxicokinetics · validation process · Animals · Biotransformation · Consumer Product Safety · Cosmetics · Drug Administration Routes · European Union · Humans

16 Development of an androgen reporter gene assay (AR-LUX) utilizing a human cell line with an endogenously regulated androgen receptor
article 2001    
Author: Blankvoort, B.M.G. · Groene, E.M. de · Meeteren-Kreikamp, A.P. van · Witkamp, R.F. · Rodenburg, R.J.T. · Aarts, J.M.M.J.G.
Keywords: Nutrition · Aldosterone · Androgen · Androgen receptor · Androstanolone · Bolasterone · Dexamethasone · Epigallocatechin gallate · Estradiol · Forskolin · Luciferase · Progesterone · Retinoic acid · Trenbolone · Vitamin D · Assay · Cancer cell culture · Controlled study · Genetic transcription · Genetic transfection · Human · Human cell · Priority journal · Reliability · Reporter gene · Transcription regulation · Validation process · Aldosterone · Androgens · Breast Neoplasms · Dexamethasone · Down-Regulation · Estradiol · Genes, Regulator · Genes, Reporter · Humans · Luciferases · Metribolone · Receptors, Androgen · Transfection · Tumor Cells, Cultured
[Abstract]

17 Identification of pitfalls in the analysis of heat capacity changes of β-lactoglobulin A
article 2005    
Author: Teeffelen, A.M.M. van · Meinders, M.B.J. · Jongh, H.H.J. de
Keywords: Nutrition · Food technology · Calorimetry · Heat capacity · Protein · Spectroscopy · Thermodynamics · beta lactoglobulin · tryptophan · article · circular dichroism · data analysis · differential scanning calorimetry · fluorescence · protein conformation · protein denaturation · protein folding · sensitivity analysis · thermal analysis · ultraviolet radiation · validation process · Animals · Calorimetry · Calorimetry, Differential Scanning · Cattle · Circular Dichroism · Heat · Lactoglobulins · Milk · Protein Denaturation · Protein Folding · Sensitivity and Specificity · Spectrometry, Fluorescence · Temperature · Thermodynamics · Tryptophan · Ultraviolet Rays · Urea
[Abstract]

18 Detecting psychosocial problems among 5-6-year-old children in Preventive Child Health Care: The validity of a short questionnaire used in an assessment procedure for detecting psychosocial problems among children
article 2003    
Author: Vogels, T. · Reijneveld, S.A. · Brugman, E. · Hollander-Gijsman, M.den · Verhulst, F.C. · Verloove-Vanhorick, S.P.
Keywords: Health · Children · Mental health · Questionnaire · Child health care · Child parent relation · Emotion · Health status · Major clinical study · Priority journal · Psychosocial disorder · Reliability · Risk factor · Social aspect · Validation process · Child · Child Behavior Disorders · Child Health Services · Child, Preschool · Female · Humans · Logistic Models · Male · Mass Screening · Mood Disorders · Netherlands · Parent-Child Relations · Parents · Psychometrics · Questionnaires · Reproducibility of Results
[Abstract]

19 Signalering van beginnende Alzheimer-dementie in de huisartspraktijk: Ontwikkeling en validering van de observatie lijst voor vroege symptomen van dementie (OLD) [Observation of early symptoms of Alzheimer dementia in general practice: Development and validation of the observation list for early signs of dementia (OLD)]
article 2001    
Author: Hopman-Rock, M. · Tak, E.C.P.M. · Staats, P.G.M. · Jonker, C. · Wind, A.W.
Keywords: Health · Alzheimer disease · Controlled study · General practice · Major clinical study · Rating scale · Statistical analysis · Symptomatology · Validation process · Aged · Aged, 80 and over · Alzheimer Disease · Family Practice · Female · Humans · Male · Mass Screening · Netherlands · Neuropsychological Tests · Predictive Value of Tests · Psychiatric Status Rating Scales · Reproducibility of Results · Sampling Studies · Lepisosteidae
[Abstract]

20 Development, Validation and ECM Embedment of a Physics-Based SCR on Filter Model
article 2016    
Author: Ramesh, S. · Nieuwenhof, R.J.C. · Seykens, X. · Srinivasan, S. · Sharma, G.
Keywords: Informatics Physics · Automobiles · Automotive engineering · Bandpass filters · Real time control · Turnaround time · Engine test benches · Model based control algorithms · Model parameter identifications · Real time capability · Real-time implementations · Reduction technologies · Steady state and transients · Validation process · Commercial vehicles · Industrial Innovation · Fluid & Solid Mechanics · PT - Power Trains · TS - Technical Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 68 found. Next | Sort by date