Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 20 of 35 found. Next | Sort by date

1 Is current risk assessment of non-genotoxic carcinogens protective?
article 2018    
Author: Braakhuis, H.M. · Slob, W. · Olthof, E.D. · Wolterink, G. · Zwart, E.P. · Gremmer, E.R. · Rorije, E. · Benthem, J. van · Woutersen, R. · Laan, J.W. van der · Luijten, M.
Keywords: Health · Benchmark dose approach · Carcinogenicity · Chemicals · No-Observed-Adverse-Effect-Level · Non-genotoxic carcinogens · Repeated dose toxicity · Risk assessment · Subchronic toxicity
[Abstract]

2 Chronic toxicity and carcinogenicity study of erythritol in rats
article 1996    
Author: Lina, B.A.R. · Bos-Kuijpers, M.H.M. · Til, H.P. · Bär, A.
Keywords: erythritol · animal experiment · article · carcinogenicity · chronic toxicity · controlled study · female · kidney calcification · male · nephrotoxicity · nonhuman · priority journal · rat · Acetylglucosaminidase · Animals · Body Weight · Carcinogenicity Tests · Carcinogens · Electrolytes · Erythritol · Female · gamma-Glutamyltransferase · Kidney · Kidney Tubules · Liver · Male · Mannitol · Muramidase · Organ Size · Proteinuria · Rats · Rats, Wistar · Sweetening Agents · Animalia
[Abstract]

3 Inhaled formaldehyde: Evaluation of sensory irritation in relation to carcinogenicity
article 2006    
Author: Arts, J.H.E. · Rennen, M.A.J. · Heer, C.de
Keywords: Health · Toxicology and Applied Pharmacology · Benchmark dose · Carcinogenicity · Formaldehyde · Sensory irritation · formaldehyde · article · carcinogenicity · computer program · eye irritation · human · nonhuman · nose injury · nose irritation · odor · priority journal · rating scale · respiratory tract disease · sense organ · smelling · symptomatology · Administration, Inhalation · Air Pollutants · Animals · Carcinogens · Carcinoma · Eye · Formaldehyde · Humans · Inhalation Exposure · Irritants · Nasal Mucosa · No-Observed-Adverse-Effect Level · Nose Neoplasms · Occupational Exposure · Pharynx · Risk Assessment · Animalia
[Abstract]

4 Carcinogenicity
article 2005    
Author: Maurici, D. · Aardema, M. · Corvi, R. · Kleber, M. · Krul, C.A.M. · Laurent, C. · Loprieno, N. · Pasanen, M. · Pfuhler, S. · Phillips, B. · Prentice, D. · Sabbioni, E. · Sanner, T. · Vanparys, P.
Keywords: Health · Biomedical Research · animal testing alternative · carcinogenesis · carcinogenicity · cell communication · cell culture · cell transformation · gap junction · genotoxicity · heterozygosity · nonhuman · priority journal · review · risk assessment · standardization · transgenic mouse · validation process · Animal Testing Alternatives · Animals · Carcinogenicity Tests · Carcinogens · Cell Transformation, Neoplastic · Cells, Cultured · Consumer Product Safety · Cosmetics · European Union · Gap Junctions · Mice · Mice, Transgenic · Quantitative Structure-Activity Relationship · Rats · Animalia · Mus musculus

5 Controlling persistent organic pollutants-what next?
article 1998    
Author: Vallack, H.W. · Bakker, D.J. · Brandt, I. · Broström-Lundén, E. · Brouwer, A. · Bull, K.R. · Gough, C. · Guardans, R. · Holoubek, I. · Jansson, B. · Koch, R. · Kuylenstierna, J. · Lecloux, A. · Mackay, D. · McCutcheon, P. · Mocarelli, P. · Taalman, R.D.F. · Weavers, N.G.
Keywords: Environment · Bioaccumulation · Biomagnification · Carcinogenicity · Chronic toxicity · Endocrine disruption · Global distillation · Immunotoxicity · Monitoring · Persistence · Persistent organic pollutants · Risk assessment · Chlorinated hydrocarbon · Dioxin · Organic compound · Organochlorine pesticide · Pesticide · Pesticide residue · Polychlorinated dibenzodioxin · Polychlorinated dibenzofuran · Polycyclic aromatic hydrocarbon · Bioaccumulation · Carcinogenicity · Environmental exposure · Cnvironmental monitoring · Environmental protection · Human · Immunotoxicity · Pollution control · Pollution transport · Priority journal · Review · Risk assessment
[Abstract]

6 Toxicity and carcinogenicity of acidogenic or alkalogenic diets in rats; effects of feeding NH4Cl, KHCO3 or KCl
article 2004    
Author: Lina, B.A.R. · Kuijpers, M.H.M.
Keywords: Toxicology · Toxicology and Applied Pharmacology · Acid-base balance · Ammonium chloride · Carcinogenicity · Oncocytic tubules · Potassium bicarbonate · Potassium chloride · Toxicity · ammonium chloride · calcium · potassium · potassium carbonate · potassium chloride · acid base balance · aciduria · animal cell · animal experiment · animal tissue · article · bladder carcinoma · calcium urine level · carcinogenicity · controlled study · diet supplementation · feeding · female · growth retardation · hyperplasia · incidence · kidney mass · male · metabolic acidosis · nonhuman · oncocytoma · papilloma · potassium blood level · rat · urine pH · Acid-Base Equilibrium · Ammonium Chloride · Animals · Bicarbonates · Blood Gas Analysis · Bone and Bones · Calcium · Carcinogenicity Tests · Carcinogens · Diet · Drinking · Eating · Feces · Growth · Hydrogen-Ion Concentration · Male · Neoplasms · Organ Size · Phosphorus · Potassium Chloride · Potassium Compounds · Quaternary Ammonium Compounds · Rats · Rats, Wistar · Sex Characteristics
[Abstract]

7 Procedures for health risk assessment in Europe
article 2001    
Author: Seeley, M.R. · Tonner-Navarro, L.E. · Beck, B.D. · Deskin, R. · Feron, V.J. · Johanson, G. · Bolt, H.M.
Keywords: Cancer classification · Occupational exposure limits · Risk assessment · article · cancer classification · carcinogenicity · drug classification · Europe · health hazard · human · occupational exposure · priority journal · risk assessment · socioeconomics · Animals · Carcinogens · Europe · Health Status Indicators · Humans · Occupational Exposure
[Abstract]

8 Long- and medium-term carcinogenicity studies in animals and short-term genotoxicity tests.
article 1999    
Author: Feron, V.J. · Schwarz, M. · Hemminki, K. · Krewski, D.
Keywords: Toxicology · biological marker · mutagenic agent · animal · bioassay · carcinogen testing · human · methodology · mouse · review · species difference · time · transgenic mouse · Animals · Biological Assay · Biological Markers · Carcinogenicity Tests · Humans · Mice · Mice, Transgenic · Mutagens · Research Design · Species Specificity · Time Factors

9 Assessment of human exposure to fumonisin B1
article 1998    
Author: Nijs, M. de · Egmond, H.P. van · Nauta, M. · Rombouts, F.M. · Notermans, S.H.W.
Keywords: Nutrition · Exposure assessment · Fumonisin B1 · Public health · Carcinogenicity · Celiac disease · Dermatitis herpetiformis · Esophagus cancer · Maize · Mycotoxin · Netherlands · Toxicity testing · Carboxylic Acids · Fumonisins · Humans · Mycotoxins · Netherlands · Risk Management · Zea mays · Fungi · Fusarium · Zea mays
[Abstract]

10 The FEMA GRAS assessment of α,β-unsaturated aldehydes and related substances used as flavor ingredients
article 2008    
Author: Adams, T.B. · Gavin, C.L. · Taylor, S.V. · Waddell, W.J. · Cohen, S.M. · Feron, V.J. · Goodman, J. · Rietjens, I.M.C.M. · Marnett, L.J. · Portoghese, P.S. · Smith, R.L.
Keywords: Nutrition · α,β-Unsaturated aldehydes · FEMA GRAS · Flavor ingredients · Genotoxicity · 2 hexenal · aldehyde · flavoring agent · sorbic acid · carcinogenicity · chemical analysis · flavor · genotoxicity · hydrolysis · reproductive toxicity · review · safety · Aldehydes · Animals · Carcinogens · Flavoring Agents · Food Analysis · Humans · Mutagens · Reproduction · Animalia
[Abstract]

11 Changing the field of carcinogenicity testing of human pharmaceuticals by emphasizing mode of action
article 2017    
Author: Laan, J.W. van der · Duijndam, B. · Hoorn, T. van den · Woutersen, R. · Water, B. van de
Keywords: Nutrition · Carcinogenicity testing · Genomic approaches · Mode of action · Nuclear Receptors · Pharmaceuticals · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

12 Prediction of carcinogenic potential of chemicals using repeated-dose (13-week) toxicity data
article 2016    
Author: Woutersen, R.A. · Soffers, A.E.M.F. · Kroese, E.D. · Krul, C.A.M. · Laan, J.W. van der · Benthem, J. van · Luijten, M.
Keywords: Biology · Carcinogenicity · Non-genotoxic carcinogens · Predictivity · Preneoplastic lesions · Rat · Risk assessment · Sub-chronic toxicity · Tumours · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

13 Evaluation of the Xpa-Deficient Transgenic Mouse Model for Short-Term Carcinogenicity Testing: 9-Month Studies with Haloperidol, Reserpine, Phenacetin, and D-Mannitol
article 2004    
Author: Lina, B.A.R. · Woutersen, R.A. · Bruijntjes, J.P. · Benthem, J. van · Berg, J.A.H. van den · Monbaliu, J. · Thoolen, B.J.J.M. · Beems, R.B. · Kreijl, C.F. van
Keywords: Biology · Toxicology and Applied Pharmacology · Carcinogenicity testing · Carcinogens · DNA repair deficient · Knockout mice · Xpa · Xpa/p53 · haloperidol · mannitol · phenacetin · reserpine · animal experiment · animal tissue · article · cancer incidence · carcinogen testing · controlled study · DNA repair · evaluation · female · hyperplasia · kidney tumor · knockout mouse · male · maximum tolerated dose · mouse · nonhuman · priority journal · rare disease · survival · target organ · transgenic mouse · Administration, Oral · Animals · Carcinogenicity Tests · Diet · Disease Models, Animal · DNA-Binding Proteins · Dose-Response Relationship, Drug · Haloperidol · Mannitol · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Neoplasms, Experimental · Phenacetin · Reproducibility of Results · Reserpine · Time Factors · Xeroderma Pigmentosum Group A Protein · Animalia · Mus musculus · Rodentia
[Abstract]

14 Hazard assessment of nitrosamine and nitramine by-products of amine-based CCS: Alternative approaches
article 2015    
Author: Buist, H.E. · Devito, S. · Goldbohm, R.A. · Stierum, R.H. · Venhorst, J. · Kroese, E.D.
Keywords: Nutrition · Carbon capture and storage · Carcinogenicity · Cell transformation assay · Mutagenicity · Nitramines · Nitrosamines · Predictive in vitro models · Predictive in vivo models · QSARs · Transgenic animal test · Aniline derivative · Nitrobenzene derivative · Animal · Biological model · Carbon sequestration · Carcinogen testing · Cell transformation · Chemical structure · Chemically induced · Chemistry · LD50 · Mutagen testing · Neoplasm · Procedures · Quantitative structure activity relation · Risk assessment · Transgenic mouse · Aniline Compounds · Animals · Carbon Sequestration · Carcinogenicity Tests · Cell Transformation, Neoplastic · Lethal Dose 50 · Mice, Transgenic · Models, Biological · Molecular Structure · Mutagenicity Tests · Neoplasms · Nitrobenzenes · Quantitative Structure-Activity Relationship · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

15 Modification of human serum albumin by acrylamide at cysteine-34: A basis for a rapid biomonitoring procedure (Letter to the editor)
article 2003    
Author: Noort, D. · Fidder, A. · Hulst, A.G.
Keywords: Toxicology · Cysteine 34 · Unclassified drug · Amino terminal sequence · Bioavailability · Biological monitoring · Blood sampling · Carcinogenicity · Diet · Exposure · Humans · Instrumentation · Protein isolation · Protein modification · Protein processing · Reaction analysis · Sequence analysis · Spectrometry · Alkylation · Serum albumin · Spectrometry, Mass, Electrospray Ionization · Acrylamide, 79-06-1 · Cysteine, 4371-52-2, 52-89-1, 52-90-4 · Human serum albumin, 9048-49-1 · Acrylamides · Biological markers

16 Toxicokinetics and metabolism
article 2005    
Author: Coecke, S. · Blaauboer, B.J. · Elaut, G. · Freeman, S. · Freidig, A. · Gensmantel, N. · Hoet, P. · Kapoulas, V.M. · Ladstetter, B. · Langley, G. · Leahy, D. · Mannens, G. · Meneguz, A. · Monshouwer, M. · Nemery, B. · Pelkonen, O. · Pfaller, W. · Prieto, P. · Proctor, N. · Rogiers, V. · Rostami-Hodjegan, A. · Sabbioni, E. · Steiling, W. · Sandt, J.J.M. van de
Keywords: Toxicology · Food and Chemical Risk Analysis · cosmetic · acute toxicity · artificial membrane · bioavailability · biotransformation · carcinogenicity · cell line · cell strain CACO 2 · computer model · concentration response · electric resistance · eye irritation · genotoxicity · human · metabolism · nonhuman · phototoxicity · plasma protein binding · practice guideline · priority journal · reproductive toxicity · review · skin absorption · skin sensitization · species difference · toxicokinetics · validation process · Animals · Biotransformation · Consumer Product Safety · Cosmetics · Drug Administration Routes · European Union · Humans

17 Safety evaluation of synthetic β-carotene
article 1999    
Author: Woutersen, R.A. · Wolterbeek, A.P.M. · Appel, M.J. · Berg, H. van den · Goldbohm, R.A. · Feron, V.J.
Keywords: Toxicology · Absorption · Cancer prevention · Distribution · Lung cancer · Toxicity · beta carotene · cancer risk · carcinogenicity · chronic toxicity · drug absorption · drug distribution · drug safety · drug transport · genotoxicity · human · nonhuman · reproductive toxicity · review · toxicity testing · Absorption · Animals · Antioxidants · beta Carotene · Cell Transformation, Neoplastic · Chemoprevention · Drug Interactions · Humans · Intervention Studies · Lung Neoplasms · Mice · Rats · Rats, Sprague-Dawley · Skin Neoplasms · Smoking · Animalia
[Abstract]

18 Effects of long term feeding of raw soya bean flour on virus- induced pancreatic carcinogenesis in guinea fowl
article 1999    
Author: Kirev, T. · Woutersen, R.A. · Kiril, A.
Keywords: Nutrition · Guinea fowl · Pancreatic carcinogenesis · Raw soya bean flour · Bird · Carcinogenesis · Diet · Histology · Microscopy · Pancreas cancer · Priority journal · Retrovirus · Soybean · Virus infection · Animals · Animals, Newborn · Body Weight · Carcinogenicity Tests · Cocarcinogenesis · Female · Flour · Hyperplasia · Male · Pancreas · Pancreatic Ducts · Pancreatic Neoplasms · Poultry · Random Allocation · Retroviridae · Retroviridae Infections · Soybeans · Tumor Virus Infections
[Abstract]

19 Genotoxicity evaluation of wood-derived and vegetable oil-derived stanol esters
article 1999    
Author: Turnbull, D. · Frankos, V.H. · Delft, J.H.M. van · Vogel, N. de
Keywords: Nutrition · Fatty acid ester · Vegetable oil · Chemical structure · Chromosome aberration · Food safety · Gene mutation · Genotoxicity · Mammal cell · Priority journal · Salmonella typhimurium · Wood · Animals · Carcinogenicity Tests · CHO Cells · Chromosome Aberrations · Cricetinae · DNA Mutational Analysis · Evaluation Studies · Mice · Mutagens · Phytosterols · Plant Oils · Salmonella typhimurium · Tumor Cells, Cultured · Wood · Bacteria (microorganisms) · Mammalia · Salmonella typhimurium · Typhimurium
[Abstract]

20 Toxicologic profile of acrylonitrile
article 1998    
Author: Woutersen, R.A.
Keywords: Carcinogenicity · Mechanism · Oral · Animal experiment · Animal model · Brain tumor · Conference paper · Genetics · Inhalation · Inhalational drug administration · Mammal · Mouse · Mouth · Nonhuman · Oral drug administration · Toxicology · Acrylonitrile · Administration, Oral · Animals · Carcinogens · Disease Models, Animal · Dogs · Guinea Pigs · Humans · Inhalation Exposure · Lethal Dose 50 · Mice · Mutagens · Rabbits · Rats · Risk Assessment · Animalia · Mammalia
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 35 found. Next | Sort by date