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1 Adenosine 3':5'-cyclic monophosphate induces regulated secretion of tissue-type plasminogen activator and von Willebrand factor from cultured human endothelial cells
article 1998    
Author: Hegeman, R.J. · Eijnden-Schrauwen, Y. van den · Emeis, J.J.
Keywords: 8-Bromo Cyclic Adenosine Monophosphate · Adenosine · Bucladesine · Calcium · Cells, Cultured · Cholera Toxin · Cyclic AMP · Endothelium, Vascular · Epoprostenol · Forskolin · Humans · Isoproterenol · Second Messenger Systems · Secretory Rate · Thrombin · Tissue Plasminogen Activator · von Willebrand Factor
[Abstract]

2 Transport of glutathione A conjugates by the multifrug resistance protein 1
article 1997    
Author: Evers, R. · Cnubben, N.H.P. · Wijnholds, J. · Deemter, L. van · Bladeren, P.J. van · Borst, P.
Keywords: GS-X pump · Multidrug resistance · Adenosine Triphosphate · Animals · Biological Transport · Cell Line · Cell Polarity · Cyclic AMP · Dogs · Erythrocytes · Ethacrynic Acid · Glutathione · Humans · Kidney · Methotrexate · Mice · Mice, Mutant Strains · Microsomes · P-Glycoprotein · Prostaglandins A, Synthetic · Stereoisomerism
[PDF] [Abstract]

3 Synthesis, storage and regulated secretion of tissue-type plasminogen activator by cultured rat heart endothelial cells
article 1998    
Author: Emeis, J.J. · Hoogen, C.M. van den · Diglio, C.A.
Keywords: Health · 8 bromo cyclic amp · calcimycin · cholera toxin · forskolin · phorbol 13 acetate 12 myristate · plasminogen activator inhibitor · retinoic acid · thrombin · tissue plasminogen activator · urokinase · animal cell · article · controlled study · heart · nonhuman · priority journal · protein secretion · protein synthesis · rat · vascular endothelium
[Abstract]

4 On the role of bradykinin in secretion from vascular endothelial cells
article 1992    
Author: Emeis, J.J. · Tranquille, N.
Keywords: 8-Bromo Cyclic Adenosine Monophosphate · Animal · Atrial Natriuretic Factor · Bradykinin · Calcium · Calcium Channel Blockers · Cyclic AMP · Cyclic GMP · Endothelium, Vascular · Forskolin · Hindlimb · Kinetics · Male · Nitroprusside · Perfusion · Rats · Rats, Wistar · Receptors, Bradykinin · Receptors, Neurotransmitter · Tissue Plasminogen Activator · von Willebrand Factor
[Abstract]

5 Endothelial permeability for macromolecules: Mechanistic aspects of pathophysiological modulation
article 1997    
Author: Hinsbergh, V.W.M. van
Keywords: Actins · Animals · Base Sequence · Blood Proteins · Calcium · Capillary Permeability · Cyclic AMP · Cyclic GMP · Endothelium, Vascular · Humans · Intercellular Junctions · Macromolecular Substances · Molecular Sequence Data · Myosin-Light-Chain Kinase · Myosins · Nitric Oxide · Permeability · Phosphoprotein Phosphatase · Phosphorylation

6 The role of cyclic nucleotides in the release of tissue-type plasminogen activator and von Willebrand factor
article 1993    
Author: Tranquille, N. · Emeis, J.J.
Keywords: 8 bromo cyclic amp · adenylate cyclase · atrial natriuretic factor · bradykinin · cyclic nucleotide · forskolin · guanylate cyclase · n(g) nitroarginine · nitric oxide · nitroprusside sodium · thrombocyte activating factor · animal experiment · controlled study · enzyme activation · enzyme inhibition · hindlimb · nonhuman · perfusion · priority journal · protein secretion · 8-Bromo Cyclic Adenosine Monophosphate · Adenylate Cyclase · Animal · Atrial Natriuretic Factor · Bradykinin · Cyclic AMP · Cyclic GMP · Endothelium, Vascular · Forskolin · Guanylate Cyclase · Male · Nitroprusside · Platelet Activating Factor · Rats · Rats, Wistar · Secretory Rate · Tissue Plasminogen Activator · von Willebrand Factor
[Abstract]

7 Stereoselectivity at the B2-adrenoceptor on macrophages is a major determinant of the anti-inflammatory effects of B2-agonists
article 2000    
Author: Izeboud, C.A. · Vermeulen, R.M. · Zwart, A. · Vos, H.P. · Miert, A.S.J.P.A.M. van · Witkamp, R.F.
Keywords: β-Adrenoceptor · Stereoselectivity · 3 isopropylamino 1 (7 methyl 4 indanyloxy) 2 butanol · 4 (3 tert butylamino 2 hydroxypropoxy) 2 benzimidazolone · Aprotinin · Benzylsulfonyl fluoride · Beta 2 adrenergic receptor · Beta 2 adrenergic receptor blocking agent · Beta 2 adrenergic receptor stimulating agent · Carmoterol · cyclic AMP · Interleukin 10 · Lipopolysaccharide · Tumor necrosis factor alpha · Xamoterol · Beta adrenergic receptor stimulating agent · Nonsteroid antiinflammatory agent · Antiinflammatory activity · Stereochemistry · Cell culture · Cell membrane · Drug antagonism · Metabolism · Radioassay · Signal transduction · Stereoisomerism · Adrenergic beta-Agonists · Anti-Inflammatory Agents, Non-Steroidal · Cell Membrane · Cells, Cultured · Cyclic AMP · Humans · Interleukin-10 · Lipopolysaccharides · Macrophages · Radioligand Assay · Receptors, Adrenergic, beta-2 · Signal Transduction · Stereoisomerism · Tumor Necrosis Factor-alpha
[Abstract]

8 Stimulators of tissue-type plasminogen activator
article 1996    
Author: Kooistra, T. · Lansink, M. · Emeis, J.J.
Keywords: Health · 4 [2 (5,6,7,8 tetrahydro 5,5,8,8 tetramethyl 2 naphthyl) 1 propenyl]benzoic acid · Benzodiazepine derivative · Butyric acid · Cyclic amp · Protein kinase c · Retinoic acid · Retinoid · Tissue plasminogen activator · Trichostatin a · U 34599 · U 46195 · U 51477 · Unclassified drug · Endothelium cell · Fibrinolysis · Human · Nonhuman · Review
[Abstract]

9 Role of RhoA and Rho kinase in lysophosphatidic acid-induced endothelial barrier dysfunction.
article 2000    
Author: Nieuw Amerongen, G.P. van · Vermeer, M.A. · Hinsbergh, V.W. van
Keywords: Biology · Amides · Calcium · Cell Membrane Permeability · Cells, Cultured · Cyclic AMP · Cytoskeleton · Dose-Response Relationship, Drug · Endothelium, Vascular · Enzyme Activation · Enzyme Inhibitors · Horseradish Peroxidase · Humans · Intracellular Signaling Peptides and Proteins · Myosin Light Chains · Phosphatidic Acids · Phosphorylation · Protein-Serine-Threonine Kinases · Pyridines · rhoA GTP-Binding Protein · Thrombin · Time Factors · Umbilical Veins
[Abstract]

10 Beta-adrenergic receptor agonists induce the release of granulocyte chemotactic protein-2, oncostatin M, and vascular endothelial growth factor from macrophages
article 2006    
Author: Verhoeckx, K.C.M. · Doornbos, R.P. · Witkamp, R.F. · Greef, J. van der · Rodenburg, R.J.T.
Keywords: Biology · Analytical research · β2-adrenergic receptor · β2-adrenergic receptor agonist · cAMP · Clenbuterol · CXCL6 · GCP-2 · Oncostatin M · VEGF · Zilpaterol · 3 isopropylamino 1 (7 methyl 4 indanyloxy) 2 butanol · beta 2 adrenergic receptor · beta 2 adrenergic receptor blocking agent · beta 2 adrenergic receptor stimulating agent · bronchodilating agent · butyryl cyclic AMP · chemokine · chemokine cxcl 6 · clenbuterol · Escherichia coli lipopolysaccharide · forskolin · oncostatin M · prostaglandin E2 · unclassified drug · vasculotropin · zilpaterol · angiogenesis · article · asthma · controlled study · drug potency · histiocytic lymphoma · human · human cell · lymphoma cell · macrophage · neutrophil · priority journal · upregulation · Adrenergic beta-Agonists · Bucladesine · Chemokines, CXC · Clenbuterol · Cyclic AMP · Cytokines · Dinoprostone · Forskolin · Humans · Lipopolysaccharides · Macrophage Activation · Macrophages · Oncostatin M · Trimethylsilyl Compounds · U937 Cells · Up-Regulation · Vascular Endothelial Growth Factor A
[Abstract]

11 Inhibitory effects of the β2-adrenergic receptor agonist zilpaterol on the LPS-induced production of TNF-α in vitro and in vivo
article 2005    
Author: Verhoeckx, K.C.M. · Doornbos, R.P. · Greef, J. van der · Witkamp, R.F. · Rodenburg, R.J.T.
Keywords: Biology Pharmacology · Analytical research · 3 isopropylamino 1 (7 methyl 4 indanyloxy) 2 butanol · alprenolol · atenolol · bacterium lipopolysaccharide · beta 1 adrenergic receptor blocking agent · beta 2 adrenergic receptor blocking agent · beta 2 adrenergic receptor stimulating agent · clenbuterol · cyclic AMP · formoterol · isoprenaline · propranolol · salbutamol · tumor necrosis factor alpha · unclassified drug · zilpaterol · animal experiment · antiinflammatory activity · article · cattle · cell strain U937 · controlled study · cytokine production · dose response · drug effect · drug receptor binding · drug structure · human · human cell · inflammation · macrophage · male · nonhuman · priority journal · rat · rat strain · Adrenergic beta-Agonists · Animals · Cattle · Cyclic AMP · Dose-Response Relationship, Drug · Escherichia coli · Humans · Immunologic Factors · Lipopolysaccharides · Macrophage Activation · Male · Rats · Rats, Wistar · Trimethylsilyl Compounds · Tumor Necrosis Factor-alpha · U937 Cells · Animalia · Bacteria (microorganisms) · Bos taurus · Rattus norvegicus
[Abstract]

12 Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous System only in insulin-sensitive mice
article 2011    
Author: Coomans, C.P. · Geerling, J.J. · Guigas, B. · Hoek, A.M. van den · Parlevliet, E.T. · Ouwens, D.M. · Pijl, H. · Voshol, P.J. · Rensen, P.C.N. · Havekes, L.M. · Romijn, J.A.
Keywords: Health Biology · Brain · Brown adipose tissue · Insulin resistance · Lipid metabolism · Lipoprotein lipase · Triglycerides · adenosine triphosphate sensitive potassium channel · CD36 antigen · cyclic AMP · fatty acid · insulin · leptin · serum albumin · tolbutamide · triacylglycerol · animal experiment · animal model · animal tissue · brown adipose tissue · central nervous system · channel gating · controlled study · drug administration route · drug distribution · drug half life · drug targeting · fatty acid metabolism · fatty acid retention · hormone action · hyperinsulinemia · insulin action · insulin sensitivity · male · mouse · nonhuman · signal transduction · white adipose tissue · wild type · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

13 Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity
article 2014    
Author: Boon, M.R. · Kooijman, S. · Dam, A.D. van · Pelgrom, L.R. · Berbée, J.F.P. · Visseren, C.A.R. · Aggele, R.C. van · Hoek, A.M. van den · Sips, H.C.M. · Lombès, M. · Havekes, L.M. · Tamsma, J.T. · Guigas, B. · Meijer, O.C. · Jukema, J.W. · Rensen, P.C.N.
Keywords: Biology · Rimonabant · Sympathetic nervous system · Uncoupling protein 1 · Adrenergic receptor · Am 6545 · Cannabinoid 1 receptor · Cannabinoid 1 receptor antagonist · Cyclic AMP · Fat droplet · Lipoprotein · Triacylglycerol · Unclassified drug · Adrenergic system · Animal experiment · Animal model · Animal tissue · Appetite · Brown adipocyte · Alorimetry · Controlled study · Diet induced obesity · Dyslipidemia · Energy expenditure · Energy metabolism · Food intake · In vitro study · In vivo study · Lipid analysis · Lipid storage · Lipolysis · Lipoprotein metabolism · Male · Mouse · Nonhuman · Oxygen consumption · Physical activity · Thermogenesis · Triacylglycerol blood level · Weight change · Weight reduction · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

14 cAMP-dependent signaling regulates the adipogenic effect of n-6 polyunsaturated fatty acids
article 2008    
Author: Madsen, L. · Pedersen, L.M. · Liaset, B. · Ma, T. · Petersen, R.K. · Berg, S. van den · Pan, J. · Müller-Decker, K.M. · Dülsner, E.D. · Kleemann, R. · Kooistra, T. · Døskeland, S.O. · Kristiansen, K.
Keywords: Acids · Biomolecules · Carbohydrates · Cell culture · Cytology · Ecology · Fetal monitoring · Metabolism · Organic compounds · Oxygen · Urea · Adipogenesis · Cyclooxygenase · Demanding processes · Gluconeogenesis · Heat productions · Hepatic expressions · High protein diets · In vitro · Oxygen consumptions · Peroxisome proliferator- activated receptors · Polyunsaturated fatty acids · Prostaglandin synthesis · Protein kinases · Urea syntheses · Nutrition · Cyclic AMP dependent protein kinase · Glucagon · Glucose · Insulin · Omega 6 fatty acid · Peroxisome proliferator activated receptor gamma coactivator 1alpha · Prostaglandin synthase · Urea · Carbohydrate · Unsaturated fatty acid · Adipocyte · Adipogenesis · Amino acid sequence · Animal cell · Animal cell culture · Animal experiment · Animal model · Animal tissue · Carbohydrate diet · Controlled study · Energy conservation · Enzyme activity · Enzyme induction · Gluconeogenesis · In vitro study · In vivo study · Nonhuman · Prostaglandin synthesis · Protein diet · Protein expression · Signal transduction · Urea cycle · Biological model · C57BL mouse · Cell strain 3T3 · Chemistry · Cytology · Genetics · Mus · 3T3-L1 Cells · Adipocytes · Adipogenesis · Animals · Carbohydrates · Cyclic AMP · Fatty Acids, Omega-6 · Fatty Acids, Unsaturated · Male · Mice · Mice, Inbred C57BL · Models, Biological · Obesity · Signal Transduction · Urea · Healthy for Life · Healthy Living
[PDF] [Abstract]

15 The dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the α2-adrenergic receptors in beta cells
article 2010    
Author: Leeuw van Weenen, J.E. de · Parlevliet, E.T. · Maechler, P. · Havekes, L.M. · Romijn, J.A. · Ouwens, D.M. · Pijl, H. · Guigas, B.
Keywords: Biology · Biomedical Research · α2-Adrenergic receptor · Bromocriptine · Dopamine receptor · INS-1E cells · Insulin secretion · Mice · alpha 2 adrenergic receptor · bromocriptine · cyclic AMP · domperidone · dopamine 2 receptor stimulating agent · G protein coupled receptor · glucose · insulin · placebo · yohimbine · analytic method · animal cell · animal experiment · article · cell line · cell membrane depolarization · cell membrane potential · controlled study · drug effect · glucose clamp technique · glucose tolerance test · hyperglycemia · in vitro study · in vivo study · inhibition kinetics · insulin release · male · mouse · nonhuman · pancreas islet beta cell · priority journal · Western blotting · Animals · Bromocriptine · Cell Line · Dopamine Agonists · Dose-Response Relationship, Drug · Glucose · Insulin · Insulin-Secreting Cells · Insulinoma · Male · Mice · Mice, Inbred C57BL · Rats · Receptors, Adrenergic, alpha · Receptors, Dopamine D2
[Abstract]

16 Unheated Cannabis sativa extracts and its major compound THC-acid have potential immuno-modulating properties not mediated by CB1 and CB2 receptor coupled pathways
article 2006    
Author: Verhoeckx, K.C.M. · Korthout, H.A.A.J. · Meeteren-Kreikamp, A.P. van · Ehlert, K.A. · Wang, M. · Greef, J. van der · Rodenburg, R.J.T. · Witkamp, R.F.
Keywords: Health · Analytical research · Biomedical research · Δ9-tetrahydrocanabinoid · Δ9-tetrahydrocanabinoid acid · cAMP · Cannabis sativa · Inflammation · PC-PLC · TNF-alpha · 1 (2,4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n morpholino 1h pyrazole 3 carboxamide · 6 iodo 3 (4 methoxybenzoyl) 2 methyl 1 (2 morpholinoethyl)indole · Beta 2 adrenergic receptor stimulating agent · Cannabidiol · Cannabidiolic acid · Cannabinoid 1 receptor · Cannabinoid 2 receptor · Cannabinoid derivative · Cannabis · Delta 9 tetrahydrocannabinoid acid · Dronabinol · Immunomodulating agent · Lipopolysaccharide · Phosphatidylcholine · Phospholipase C · Tumor necrosis factor alpha · Unclassified drug · Zilpaterol · Cell strain U937 · Concentration response · Controlled study · Cytokine production · Down regulation · Drug effect · Drug mechanism · Enzyme activity · Heating · Human cell · Immunomodulation · Immunopharmacology · Immunostimulation · Long term exposure · Macrophage · Metabolism · Protein induction · Protein synthesis regulation · Supernatant · Upregulation · Cannabis · Cell Line · Cells, Cultured · Cyclic AMP · Dose-Response Relationship, Drug · Heat · Humans · Immunologic Factors · Macrophage Activation · Macrophages · Phospholipase C · Plant Extracts · Receptor, Cannabinoid, CB1 · Receptor, Cannabinoid, CB2 · Signal Transduction · Tetrahydrocannabinol · Tumor Necrosis Factor-alpha
[Abstract]

17 cGMP and nitric oxide modulate thrombin-induced endothelial permeability : Regulation via different pathways in human aortic and umbilical vein endothelial cells
article 1995    
Author: Draijer, R. · Atsma, D.E. · Laarse, A. van der · Hinsbergh, V.W.M. van
Keywords: Biology · cGMP-dependent protein kinase · cytoplasmic Ca2+ · human endothelial cells · nitric oxide · permeability · 1 [2 (4 methoxyphenyl) 2 [3 (4 methoxyphenyl)propoxy]ethyl] 1h imidazole · 5 (4 acetamidophenyl) 2(1h) pyrazinone · 8 (4 chlorophenylthio) cyclic GMP · 8 bromo cyclic GMP · atrial natriuretic factor · calcium ion · cyclic AMP · cyclic GMP · cyclic GMP dependent protein kinase · ethylene glycol 1,2 bis(2 aminophenyl) ether n,n,n',n' tetraacetic acid · forskolin · fura 2 acetoxymethyl ester · indolidan · isobutylmethylxanthine · n(g) nitroarginine methyl ester · nitric oxide · nitroprusside sodium · phosphodiesterase · rolipram · thrombin · unclassified drug · aorta · article · blood vessel permeability · calcium cell level · controlled study · endothelium cell · enzyme activation · human · human cell · macromolecule · muscle fiber contraction · priority journal · umbilical vein · vascular endothelium · 3',5'-Cyclic-Nucleotide Phosphodiesterase · Aorta · Arginine · Calcium · Capillary Permeability · Cyclic GMP · Endothelium, Vascular · Human · Intracellular Membranes · NG-Nitroarginine Methyl Ester · Nitric Oxide · Support, Non-U.S. Gov't · Thrombin · Umbilical Veins
[Abstract]

18 In search of secreted protein biomarkers for the anti-inflammatory effect of β2-adrenergic receptor agonists: Application of DIGE technology in combination with multivariate and univariate data analysis tools
article 2005    
Author: Verhoeckx, K.C.M. · Gaspari, M. · Bijlsma, S. · Greef, J. van der · Witkamp, R.F. · Doornbos, R.P. · Rodenburg, R.J.T.
Keywords: Pharmacology · Analytical research · β2-adrenergic receptor · Difference gel electrophoresis · Macrophage inflammatory protein-1β · Multivariate data analysis · Partial least squares discriminant analysis · Principal component analysis · Zilpaterol · adenylate kinase · beta 2 adrenergic receptor · beta 2 adrenergic receptor blocking agent · beta 2 adrenergic receptor stimulating agent · biological marker · butyryl cyclic AMP · clenbuterol · endotoxin · Escherichia coli lipopolysaccharide · formoterol · forskolin · heat shock protein · macrophage inflammatory protein 1alpha · macrophage inflammatory protein 1beta · phosphoglycerate mutase · propranolol · prostaglandin E2 · proteome · salbutamol · unclassified drug · zilpaterol · adrenergic system · analytic method · antiinflammatory activity · article · controlled study · data analysis · discriminant analysis · human · human cell · inflammation · liquid chromatography · macrophage · mass spectrometry · multivariate analysis · nucleotide sequence · principal component analysis · priority journal · protein expression · protein secretion · proteomics · statistical analysis · two dimensional difference gel electrophoresis · two dimensional gel electrophoresis · Adrenergic Agonists · Adrenergic beta-Antagonists · Anti-Inflammatory Agents · Biological Markers · Cluster Analysis · Down-Regulation · Electrophoresis, Gel, Two-Dimensional · Enzyme-Linked Immunosorbent Assay · Humans · Immunoassay · Inflammation · Lipopolysaccharides · Macrophage Inflammatory Protein-1 · Macrophages · Mass Spectrometry · Monocytes · Multivariate Analysis · Principal Component Analysis · Propranolol · Proteome · Proteomics · Receptors, Adrenergic, beta-2 · Statistics · Trimethylsilyl Compounds · U937 Cells · Up-Regulation · Escherichia coli
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 18 of 18 found. | Sort by date