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Showing 1 to 7 of 7 found. | Sort by date

1 Safety evaluation of synthetic β-carotene
article 1999    
Author: Woutersen, R.A. · Wolterbeek, A.P.M. · Appel, M.J. · Berg, H. van den · Goldbohm, R.A. · Feron, V.J.
Keywords: Toxicology · Absorption · Cancer prevention · Distribution · Lung cancer · Toxicity · beta carotene · cancer risk · carcinogenicity · chronic toxicity · drug absorption · drug distribution · drug safety · drug transport · genotoxicity · human · nonhuman · reproductive toxicity · review · toxicity testing · Absorption · Animals · Antioxidants · beta Carotene · Cell Transformation, Neoplastic · Chemoprevention · Drug Interactions · Humans · Intervention Studies · Lung Neoplasms · Mice · Rats · Rats, Sprague-Dawley · Skin Neoplasms · Smoking · Animalia
[Abstract]

2 Dermatokinetics of didecyldimethylammonium chloride and the influence of some commercial biocidal formulations on its dermal absorption in vitro
article 2007    
Author: Buist, H.E. · Heer, C. de · Burgsteden, J.A. van · Sandt, J.J.M. van de
Keywords: Chemistry · Biomedical Research · Biocides · Dermal absorption · Dermatokinetics · Didecyldimethylammonium chloride · Quaternary ammonium chlorides · Repeated exposure · Risk assessment · Single exposure · Skin barrier · Vehicle effects · Aldehyde · Biocide · Didecyldimethylammonium chloride · Adult · Aqueous solution · Concentration (parameters) · Correlation analysis · Drug absorption · Drug distribution · Drug exposure · Drug formulation · Drug penetration · Epidermis · Female · Human · Human cell · Human tissue · In vitro study · Priority journal · Skin absorption · Skin permeability · Stratum corneum · Toxicokinetics · Administration, Cutaneous · Cells, Cultured · Chemistry, Pharmaceutical · Disinfectants · Humans · Kinetics · Permeability · Quaternary Ammonium Compounds · Skin Absorption · Tissue Distribution
[Abstract]

3 Quantitative analysis of Tenecteplase in rat plasma samples using LC-MS/MS as an alternative for ELISA
article 2007    
Author: Buscher, B.A.P. · Gerritsen, H. · Schöll, I. van · Cnubben, N.H.P. · Brüll, L.P.
Keywords: Biology · Analytical research · Digestion · Liquid chromatography · Mass spectrometry · Plasma · Proteins · Quantitative analysis · Blood · Digestive system · Drug products · Enzymes · Sensitivity analysis · Internal standard · Tenecteplase · Trypsin · Chemical analysis · tenecteplase · animal experiment · article · blood sampling · controlled study · drug distribution · enzyme linked immunosorbent assay · liquid chromatography · mass spectrometry · nonhuman · priority journal · quantitative analysis · rat · single drug dose · Animals · Chromatography, Liquid · Enzyme-Linked Immunosorbent Assay · Fibrinolytic Agents · Rats · Sensitivity and Specificity · Tandem Mass Spectrometry · Tissue Plasminogen Activator · Rattus
[Abstract]

4 Feasibility of SPECT-CT imaging to study the pharmacokinetics of antisense oligonucleotides in a mouse model of Duchenne muscular dystrophy
article 2017    
Author: Steeg, E. van de · Läppchen, T. · Aguilera, B. · Jansen, H.T. · Muilwijk, D. · Vermue, R. · Hoorn, J.W. van der · Donato, K. · Rossin, R. · Visser, P.C. de · Vlaming, M.L.H.
Keywords: Nutrition · SPECT imaging · Antisense oligonucleotides · RNA-based therapeutics · Duchenne muscular dystrophy · Antisense oligonucleotides · Antisense oligonucleotide i 123 · Antisense oligonucleotide in 111 · Indium 111 · Iodine 123 · Tracer · Unclassified drug · Animal experiment · Animal model · Animal tissue · Controlled study · Drug distribution · Drug half life · Drug tissue level · Drug uptake · In vivo study · Male · Mouse · Mouse model · Nonhuman · Single photon emission computed tomography-computed tomography · Skeletal muscle · Target tissue · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

5 Transdermal administration of radiolabelled [14C]rotigotine by a patch formulation: A mass balance trial
article 2007    
Author: Cawello, W. · Wolff, H.M. · Meuling, W.J.A. · Horstmann, R. · Braun, M.
Keywords: Biomedical Research · carbon 14 · dopamine receptor stimulating agent · rotigotine · silicone · adult · article · clinical trial · diarrhea · dizziness · drug absorption · drug clearance · drug delivery system · drug distribution · drug elimination · drug formulation · drug metabolism · drug penetration · drug release · drug structure · drug tolerability · fatigue · human · human experiment · isotope labeling · liquid chromatography · liquid scintillation counting · male · mass balance · normal human · phase 1 clinical trial · priority journal · radioactivity · single drug dose · tandem mass spectrometry · Administration, Cutaneous · Adolescent · Adult · Carbon Radioisotopes · Chromatography, Liquid · Dopamine Agonists · Humans · Male · Middle Aged · Tandem Mass Spectrometry · Tetrahydronaphthalenes · Thiophenes
[Abstract]

6 Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous System only in insulin-sensitive mice
article 2011    
Author: Coomans, C.P. · Geerling, J.J. · Guigas, B. · Hoek, A.M. van den · Parlevliet, E.T. · Ouwens, D.M. · Pijl, H. · Voshol, P.J. · Rensen, P.C.N. · Havekes, L.M. · Romijn, J.A.
Keywords: Health Biology · Brain · Brown adipose tissue · Insulin resistance · Lipid metabolism · Lipoprotein lipase · Triglycerides · adenosine triphosphate sensitive potassium channel · CD36 antigen · cyclic AMP · fatty acid · insulin · leptin · serum albumin · tolbutamide · triacylglycerol · animal experiment · animal model · animal tissue · brown adipose tissue · central nervous system · channel gating · controlled study · drug administration route · drug distribution · drug half life · drug targeting · fatty acid metabolism · fatty acid retention · hormone action · hyperinsulinemia · insulin action · insulin sensitivity · male · mouse · nonhuman · signal transduction · white adipose tissue · wild type · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

7 Recent methodology in the phytochemical analysis of ginseng
article 2008    
Author: Angelova, N. · Kong, H.-W. · Heijden, R. van de · Yang, S.-Y. · Choi, Y.H. · Kim, H.K. · Wang, M. · Hankemeier, T. · Greef, J. van der · Xu, G. · Verpoorte, R.
Keywords: Health · Biomedical Research · Ginsenosides · Mass spectrometry · Metabolomics · Panax ginseng · Ginseng extract · Phenol · Saponin · Analytic method · Antineoplastic activity · Biosensor · Drug absorption · Drug determination · Drug distribution · Drug efficacy · Drug excretion · Drug half life · Drug metabolism · Drug safety · Drug structure · Electrospray mass spectrometry · Enzyme linked immunosorbent assay · Fourier transform mass spectrometry · Ginseng · High performance liquid chromatography · Human · Immunoregulation · Ion cyclotron resonance mass spectrometry · Liquid chromatography · Liver protection · Mass spectrometry · Metabolomics · Near infrared reflectance spectroscopy · Nonhuman · Nuclear magnetic resonance spectroscopy · Plant root · Quality control · Review · Sensitivity analysis · Structure analysis · Systems biology · Drugs, Chinese Herbal · Ginsenosides · Mass Spectrometry · Panax · Spectroscopy, Fourier Transform Infrared · Spectroscopy, Near-Infrared · Panax ginseng
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 7 of 7 found. | Sort by date