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1 Significance of particle size of benzo(A)pyrene for the induction of respiratory tract tumours in hamsters
article 1980    
Author: Feron, V.J. · Heuvel, P.D. van den · Koeter, H.B.W.M. · Beems, R.B.
Keywords: Nutrition Biology · Benzo[a]pyrene · Animal experiment · Carcinogenesis · Drug elimination · Hamster · Lung cancer · Particle size · Respiratory system · Body Weight · Female · Male · Mesocricetus · Neoplasms, Experimental · Particle Size · Respiratory System · Respiratory Tract Neoplasms · Support, U.S. Gov't, P.H.S. · Suspensions

2 Intravenous and inhalation toxicokinetics of sarin stereoisomers in atropinized guinea pigs
article 2000    
Author: Spruit, W.E.T. · Langenberg, J.P. · Trap, H.C. · Wiel, H.J. van der · Helmich, R.B. · Helden, H.P.M. van · Benschop, H.P.
Keywords: Acetylcholinesterase inhibition · Guinea pig · Intravenous bolus · Nose-only exposure · Respiratory parameters · Stereoisomers · Toxicokinetics · Animal experiment · Animal model · Binding site · Chemical warfare · Controlled study · Drug absorption · Drug elimination · Enzyme inhibition · Gas chromatography · Guinea pig · Nonhuman · Nose mucosa · Stereoisomerism · Toxicokinetics · Acetylcholinesterase · Administration, Inhalation · Animals · Area Under Curve · Atropine · Chemical Warfare Agents · Guinea Pigs · Injections, Intravenous · Male · Stereoisomerism · Acetylcholinesterase, EC 3.1.1.7 · Atropine, 51-55-8 · Chemical warfare agents · Sarin, 107-44-8
[Abstract]

3 Disposition of 14C-erythritol in germfree and conventional rats
article 1996    
Author: Ommen, B. van · Bie, B. de · Bar, A.
Keywords: Toxicology · erythritol · carbon · carbon dioxide · diagnostic agent · sweetening agent · animal experiment · article · controlled study · drug disposition · drug elimination · drug metabolism · female · germfree animal · male · nonhuman · priority journal · rat · absorption · animal · body weight · intestine · kidney · metabolism · microbiology · physiology · tissue distribution · urine · Wistar rat · Absorption · Animals · Body Weight · Carbon Dioxide · Carbon Radioisotopes · Erythritol · Female · Germ-Free Life · Intestines · Kidney · Male · Rats · Rats, Wistar · Sweetening Agents · Tissue Distribution
[Abstract]

4 A randomized three-way cross-over study in healthy pituitary-suppressed women to compare the bioavailability of human chorionic gonadotrophin (Pregnyl®) after intramuscular and subcutaneous administration
article 1998    
Author: Mannaerts, B.M.J.L. · Geurts, T.B.P. · Odink, J.
Keywords: Nutrition · Bioequivalence · Human chorionic gonadotrophin · Intramuscular · Pharmacokinetics · Subcutaneous · Chorionic gonadotropin · Adult · Area under the curve · Bioequivalence · Clinical trial · Controlled study · Dose response · Drug absorption · Drug bioavailability · Drug blood level · Drug elimination · Drug half life · Female · Human · Human experiment · Hypopituitarism · Intramuscular drug administration · Normal human · Randomized controlled trial · Subcutaneous drug administration · Administration, Oral · Adolescent · Adult · Chorionic Gonadotropin · Contraceptives, Oral · Cross-Over Studies · Dose-Response Relationship, Drug · Female · Humans · Injections, Intramuscular · Pituitary Gland
[Abstract]

5 Human safety and pharmacokinetics of the CFC alternative propellants HFC 134a (1,1,1,2-tetrafluoroethane) and HFC 227 (1,1,1,2,3,3,3-heptafluoropropane) following whole-body exposure
article 2000    
Author: Emmen, H.H. · Hoogendijk, E.M.G. · Klöpping-Ketelaars, W.A.A. · Muijser, H. · Duistermaat, E. · Ravensberg, J.C. · Alexander, D.J. · Borkhataria, D. · Rusch, G.M. · Schmit, B.
Keywords: Nutrition · Apaflurane · Cfc 12 · Chlorofluorocarbon · Dichlorodifluoromethane · Hfc 227 · Norflurane · Unclassified drug · Adult · Aerosol · Blood pressure · Central nervous system disease · Clinical trial · Concentration response · Controlled clinical trial · Controlled study · Double blind procedure · Drug blood level · Drug delivery system · Drug elimination · Drug excretion · Drug safety · Electrocardiogram · Exposure · Female · Human · Human experiment · Lung function · Male · Metered dose inhaler · Normal human · Priority journal · Pulse rate · Respiratory tract disease · Sex difference · Steady state · Vapor · Administration, Inhalation · Adult · Aerosol Propellants · Atmosphere Exposure Chambers · Blood Pressure · Chlorofluorocarbons, Methane · Dose-Response Relationship, Drug · Double-Blind Method · Electrocardiography · Female · Half-Life · Humans · Hydrocarbons, Fluorinated · Inhalation Exposure · Male · Respiratory Function Tests · Safety · Sex Characteristics
[Abstract]

6 Transdermal administration of radiolabelled [14C]rotigotine by a patch formulation: A mass balance trial
article 2007    
Author: Cawello, W. · Wolff, H.M. · Meuling, W.J.A. · Horstmann, R. · Braun, M.
Keywords: Biomedical Research · carbon 14 · dopamine receptor stimulating agent · rotigotine · silicone · adult · article · clinical trial · diarrhea · dizziness · drug absorption · drug clearance · drug delivery system · drug distribution · drug elimination · drug formulation · drug metabolism · drug penetration · drug release · drug structure · drug tolerability · fatigue · human · human experiment · isotope labeling · liquid chromatography · liquid scintillation counting · male · mass balance · normal human · phase 1 clinical trial · priority journal · radioactivity · single drug dose · tandem mass spectrometry · Administration, Cutaneous · Adolescent · Adult · Carbon Radioisotopes · Chromatography, Liquid · Dopamine Agonists · Humans · Male · Middle Aged · Tandem Mass Spectrometry · Tetrahydronaphthalenes · Thiophenes
[Abstract]

7 Antidotes to organophosphate poisoning. 2. Thiadiazole-5-carboxaldoximes
article 1979    
Author: Benschop, H.P. · Berg, G.R. van den · Hooidonk, C. van · Jong, L.P.A. de · Kientz, C.E. · Berends, F. · Kepner, L.A. · Meeter, E. · Visser, R.P.L.S.
Keywords: Biology · Acetylcholinesterase · Antidote · Atropine · Cholinesterase reactivator · Diacetyl oxime · Enzyme · Obidoxime P · Paraoxon · Sarin · Tri ortho cresyl phosphate · 1,2,3 thiadiazole 5 carboxaldoxime · 2 (hydroximinomethyl) 1 methylpyridinium salt · 2 methyl 1,2,3 thiadiazolium salt carboxaldoxime · 3 methyl 1,2,3 thiadiazolium salt 5 carboxaldoxime · Animal experiment · Blood · Blood and hemopoietic system · Dose response · Drug administration · Drug analysis · Drug blood level · Drug comparison · Drug elimination · Drug half life · Drug interaction · Drug intoxication · Drug metabolism · Drug response · Drug screening · Drug synthesis · Drug tolerance · Drug toxicity · Drug urine level · Goat · Guinea pig · High performance liquid chromatography · Hydroximinoacetone · In vitro study · Intoxication · Intraperitoneal drug administration · Intravenous drug administration · Mouse · Nuclear magnetic resonance · Oral drug administration · Organophosphate intoxication · Pharmacokinetics · Prevention · Prophylaxis · Rabbit · Rat · Subcutaneous drug administration · Theoretical study · Therapy · Thiadiazole 5 carboxaldoxime derivative · Ultraviolet spectrophotometry · Urine · Acetylcholinesterase · Animal · Antidotes · Body Temperature · Cattle · Chemistry · Dose-Response Relationship, Drug · Enzyme Reactivators · Female · Goats · Guinea Pigs · Half-Life · In Vitro · Lethal Dose 50 · Male · Mice · Organophosphorus Compounds · Oximes · Rabbits · Rats · Rats, Inbred Strains · Sarin · Solubility · Structure-Activity Relationship
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 7 of 7 found. | Sort by date