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1 Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans
article 1988    
Author: Kempen, H.J.M. · Glatz, J.F.C. · Gevers Leuven, J.A. · Voort, H.A. van der · Katan, M.B.
Keywords: Biology · Fatty acid · Hydroxymethylglutaryl coenzyme a reductase · Lanosterol · Lathosterol · Simvastatin · Cholesterol synthesis · Clinical article · Diet · Familial hypercholesterolemia · Human cell · Normal human · Serum · Anticholesteremic Agents · Biological Markers · Cholesterol · Female · Human · Hypercholesterolemia, Familial · Isomerism · Lovastatin · Male · Simvastatin
[PDF] [Abstract]

2 Similar response to simvastatin in patients heterozygous for familial hypercholesterolemia with mRNA negative and mRNA positive mutations
article 1998    
Author: Sijbrands, E.J.G. · Lombardi, M.P. · Westendorp, R.G.J. · Gevers Leuven, J.A. · Meinders, A.E. · Laarse, A. van der · Frants, R.R. · Havekes, L.M. · Smelt, A.H.M.
Keywords: Health · Familial hypercholesterolemia · LDL receptor gene · Simvastatin · Xanthomas · Anticholesteremic Agents · Cholesterol, HDL · Cholesterol, LDL · Female · Heterozygote · Humans · Hyperlipoproteinemia Type II · Male · Middle Aged · Mutation · Receptors, LDL · RNA, Messenger · Simvastatin
[Abstract]

3 Opsporing familiaire hypercholesterolemie bij kinderen geindiceerd? Bij uitzondering wel [Search for familial hypercholesterolaemia in children indicated? Only exceptionally]
article 1997    
Author: Gevers Leuven, J.A.
Keywords: Health · Child · Cholesterol blood level · Diagnostic test · Familial hypercholesterolemia · Human · Ischemic heart disease · Note · Screening · Adolescent · Child · Cholesterol · Cholesterol, LDL · Diet, Fat-Restricted · Humans · Hyperlipoproteinemia Type II · Stress, Psychological
[Abstract]

4 Atypical xanthomatosis in apolipoprotein E-deficient mice after cholesterol feeding
article 1995    
Author: Ree, J.H. van · Gijbels, M.J.J. · Broek, W.J.A.A. van den · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · Cholesterol deposition · Familial dysbetalipoproteinemia · Gene targeting · Hypercholesterolemia · Lipoprotein metabolism · Mouse model · apolipoprotein e · cholesterol · animal experiment · animal model · article · cholesterol diet · familial hypercholesterolemia · gene targeting · histology · hyperlipoproteinemia type 3 · lipoprotein metabolism · mouse · nonhuman · priority journal · xanthomatosis · Animal · Apolipoproteins E · Cholesterol, Dietary · Human · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Support, Non-U.S. Gov't · Xanthomatosis
[Abstract]

5 An acceptor splice site mutation in intron 16 of the low density lipoprotein receptor gene leads to an elongated, internalization defective receptor
article 1993    
Author: Lombardi, P. · Hoffer, M.J.V. · Top, B. · Wit, E. de · Gevers Leuven, J.A. · Frants, R.R. · Havekes, L.M.
Keywords: Denaturating gradient gel electrophoresis · Polymerase chain reaction · Complementary dna · Low density lipoprotein receptor · Case report · Dna sequence · Familial hypercholesterolemia · Gel electrophoresis · Mutation · Pedigree analysis · Polymerase chain reaction · Adult · Amino Acid Sequence · Base Sequence · Cells, Cultured · Electrophoresis · Female · Homozygote · Human · Hypercholesterolemia, Familial · Introns · Molecular Sequence Data · Pedigree · Point Mutation · Reading Frames · Receptors, LDL · RNA Splicing · Sequence Analysis, DNA · Support, Non-U.S. Gov't
[Abstract]

6 Cardiovascular disease and mortality in statin-treated patients with familial hypercholesterolemia
article 2004    
Author: Mohrschladt, M.F. · Westendorp, R.G.J. · Gevers Leuven, J.A. · Smelt, A.H.M.
Keywords: Health · Biomedical Research · Familial hypercholesterolemia · Mortality · Prospective follow-up · Statins · Aged · Anamnesis · Cardiovascular risk · Controlled study · Follow up · Ischemic heart disease · Major clinical study · Prospective study · Statistical significance · Adult · Cardiovascular Diseases · Female · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hyperlipoproteinemia Type I · Male · Middle Aged · Myocardial Ischemia · Prognosis
[Abstract]

7 Modulating effect of the A-278C promoter polymorphism in the cholesterol 7alpha-hydroxylase gene on serum lipid levels in normolipidaemic and hypertriglyceridaemic individuals
article 2004    
Author: Hofman, M.K. · Groenendijk, M. · Verkuijlen, P.J.J.H. · Jonkers, I.J.A.M. · Mohrschladt, M.F. · Smelt, A.H.M. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · CYP7A1 · Hyperlipidaemia · Modifier gene · Polymorphism · Triglycerides · apolipoprotein E3 · cholesterol · cholesterol 7alpha monooxygenase · isoprotein · lipid · low density lipoprotein · triacylglycerol · very low density lipoprotein · controlled study · DNA polymorphism · familial hypercholesterolemia · gene control · homozygosity · hyperlipidemia · hyperlipoproteinemia type 3 · lipid blood level · major clinical study · promoter region · triacylglycerol blood level · Adult · Aged · Cholesterol 7-alpha-Hydroxylase · Female · Gene Frequency · Genotype · Humans · Hypertriglyceridemia · Male · Middle Aged · Polymorphism, Genetic · Promoter Regions (Genetics) · Triglycerides
[Abstract]

8 Effects of simvastatin on plasma lipids and apolipoproteins in familial hypercholesterolemic swine
article 1996    
Author: Hasler-Rapacz, J. · Kempen, H.J. · Princen, H.M.G. · Kudchodkar, B.J. · Lacko, A. · Rapacz, J.
Keywords: Biology · animal model · apolipoproteins · familial hypercholesterolemia · simvastatin · swine · apolipoprotein a · apolipoprotein b · apolipoprotein c3 · apolipoprotein e · high density lipoprotein cholesterol · hydroxymethylglutaryl coenzyme a reductase · lathosterol · lipid · low density lipoprotein cholesterol · phosphatidylcholine sterol acyltransferase · simvastatin · triacylglycerol · very low density lipoprotein cholesterol · animal experiment · animal model · animal tissue · article · calculation · cholesterol blood level · dose response · enzyme activity · hypercholesterolemia · hyperlipidemia · lipid analysis · lipid blood level · lipoprotein blood level · nonhuman · priority journal · statistical analysis · swine · Animals · Apolipoprotein A-I · Apolipoprotein C-III · Apolipoproteins · Apolipoproteins B · Apolipoproteins C · Apolipoproteins E · Cholesterol · Cholesterol, HDL · Cholesterol, LDL · Enzyme Inhibitors · Female · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hyperlipoproteinemia Type II · Lipids · Male · Swine · Swine Diseases · Triglycerides
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 8 of 8 found. | Sort by date