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1 Matrix metalloproteinase-9 measured in urine from bladder cancer patients is an independent prognostic marker of poor survival
article 2010    
Author: Offersen, B.V. · Knap, M.M. · Horsman, M.R. · Verheijen, J. · Hanemaaijer, R. · Overgaard, J.
Keywords: Health · Biomedical Research · creatinine · gelatinase B · adult · aged · article · bladder cancer · cancer mortality · cancer size · cancer survival · clinical assessment · correlation analysis · creatinine blood level · diagnostic value · female · human · major clinical study · male · overall survival · predictive validity · priority journal · prognosis · urinalysis
[Abstract]

2 A novel and simple immunocapture assay for determination of gelatinase-B (MMP-9) activities in biological fluids : Saliva from patients with Sjögren's syndrome contain increased latent and active gelatinase-B levels
article 1998    
Author: Hanemaaijer, R. · Visser, H. · Konttinen, Y.T. · Koolwijk, P. · Verheijen, J.H.
Keywords: Health · Activity assay · Gelatinase B · Matrix metalloproteinases (MMP) · Sjogren's syndrome · Urokinase · Animals · Antibodies, Monoclonal · Antibody Specificity · Collagenases · Female · Humans · Immunoassay · Matrix Metalloproteinase 9 · Mice · Mice, Inbred BALB C · Saliva · Sensitivity and Specificity · Sjogren's Syndrome · Tissue Inhibitor of Metalloproteinase-2 · Animalia
[Abstract]

3 Eradication of Helicobacter pylori infection favourably affects altered gastric mucosal MMP-9 levels
article 2007    
Author: Kubben, F.J.G.M. · Sier, C.F.M. · Schram, M. · Witte, T.A.M.C. · Veenendaal, R.A. · Duijn, W. van · Verheijen, J.H. · Hanemaaijer, R. · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biomedical Research · Bioactivity assay (BIA) · ELISA · Gastritis · Helicobacter pylori · Matrix metalloproteinases · MMP-2 (gelatinase A) · MMP-9 (gelatinase B) · Zymography · antibiotic agent · clarithromycin · gelatin · gelatinase A · gelatinase B · metronidazole · omeprazole · proton pump inhibitor · ranitidine · adult · aged · article · controlled study · drug activity · enzyme analysis · enzyme linked immunosorbent assay · eradication therapy · female · Helicobacter infection · Helicobacter pylori · human · major clinical study · male · priority journal · quantitative analysis · statistical significance · stomach mucosa · zymography · Adult · Aged · Anti-Infective Agents · Anti-Ulcer Agents · Biopsy · Clarithromycin · Drug Therapy, Combination · Endoscopy, Gastrointestinal · Enzyme-Linked Immunosorbent Assay · Female · Gastric Mucosa · Helicobacter Infections · Helicobacter pylori · Humans · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Metronidazole · Middle Aged · Omeprazole · Ranitidine · Treatment Outcome · Helicobacter pylori
[Abstract]

4 Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer
article 2007    
Author: Kubben, F.J.G.M. · Sier, C.F.M. · Hawinkels, L.J.A.C. · Tschesche, H. · Duijn, W. van · Zuidwijk, K. · Reijden, J.J. van der · Hanemaaijer, R. · Griffioen, G. · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biology · Biomedical Research · Activity assay · Cancer · Metalloproteinase · Prognosis · gelatinase B · lipocalin · matrix metalloproteinase inhibitor · tissue inhibitor of metalloproteinase 1 · adult · aged · article · autolysis · cancer survival · disease classification · enzyme activity · enzyme degradation · epithelium cell · female · human · human tissue · immunohistochemistry · major clinical study · male · multivariate analysis · priority journal · protein function · stomach cancer · tumor · univariate analysis · world health organization
[Abstract]

5 Tissue levels of matrix metalloproteinases MMP-2 and MMP-9 are related to the overall survival of patients with gastric carcinoma
article 1996    
Author: Sier, C.F.M. · Kubben, F.J.G.M. · Ganesh, S. · Heerding, M.M. · Griffioen, G. · Hanemaaijer, R. · Krieken, J.H.J.M. van · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biology · Gastric carcinoma · Gelatinases · Matrix metalloproteinase · Quantitative zymography · gelatinase b · proteinase · adult · cancer classification · cancer invasion · cancer survival · clinical article · controlled study · histopathology · human tissue · metastasis · priority journal · prognosis · stomach carcinoma · stomach mucosa · Aged · Collagenases · Female · Gelatinases · Humans · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Metalloendopeptidases · Middle Aged · Stomach Neoplasms · Survival Rate
[PDF] [Abstract]

6 Increased matrix metalloproteinase-8 and -9 activity in patients with infarct rupture after myocardial infarction
article 2009    
Author: Borne, S.W.M. van den · Cleutjens, J.P.M. · Hanemaaijer, R. · Creemers, E.E. · Smits, J.F.M. · Daemen, M.J.A.P. · Blankesteijn, W.M.
Keywords: Biology · Biomedical Research · Infarct rupture · Inflammation · Matrix metalloproteinases · MMP activity assay · MMP immunohistochemistry · Myocardial infarction · gelatinase A · gelatinase B · neutrophil collagenase · tissue inhibitor of metalloproteinase 1 · adult · aged · article · clinical article · controlled study · enzyme activity · female · heart · heart disease · heart infarction · human · human tissue · immunohistochemistry · infarct rupture · inflammatory cell · male · priority journal · zymography · Aged · Aged, 80 and over · Cell Count · Female · Heart Rupture, Post-Infarction · Humans · Immunohistochemistry · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 8 · Matrix Metalloproteinase 9 · Middle Aged · Myocardial Infarction · Myocarditis
[Abstract]

7 Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm doxycycline selectively depletes aortic wall neutrophils and cytotoxic t cells
article 2009    
Author: Lindeman, J.H.N. · Abdul-Hussien, H. · Bockel, J.H. van · Wolterbeek, R. · Kleemann, R.
Keywords: Health · Aneurysm · Immunology · Inflammation · Molecular biology · Trials · Doxycycline · Gelatinase B · Granulocyte colony stimulating factor receptor · Interleukin 13 · Interleukin 6 · Interleukin 8 · Antiinfective agent · CCAAT enhancer binding protein · Enzyme inhibitor · IL6 protein, human · Transcription factor AP 1 · Transcription factor RelA · Abdominal aorta aneurysm · Aged · Cytotoxic T lymphocyte · Drug effect · Drug megadose · Drug tolerability · Enzyme inhibition · Aortic Aneurysm, Abdominal · CCAAT-Enhancer-Binding Proteins · Doxycycline · Enzyme Inhibitors · Matrix Metalloproteinase 9 · Middle Aged · Neutrophils · T-Lymphocytes, Cytotoxic · Vasculitis
[PDF] [Abstract]

8 Chemically modified tetracyclines stimulate matrix metalloproteinase-s production by periodontal ligament cells
article 2006    
Author: Bildt, M.M. · Snoek-van Beurden, A.M.P. · Groot, J. de · El, B. van · Kuijpers-Jagtman, A.M. · Hoff, J.W. van den
Keywords: Biology · Biomedical Research · Chemically modified tetracyclines · Gelatin zymography · Matrix metalloproteinases · Periodontal ligament · DNA · Enzyme inhibitor · Gelatin · Gelatinase A · Gelatinase B · Recombinant protein · Tetracycline derivative · Analysis of variance · Iosynthesis · Cell culture · Chemistry · Drug antagonism · Drug effect · Human · Metabolism · Nonparametric test · Periodontal ligament · Polyacrylamide gel electrophoresis · Western blotting · Analysis of Variance · Blotting, Western · Cells, Cultured · DNA · Electrophoresis, Polyacrylamide Gel · Enzyme Inhibitors · Gelatin · Humans · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Periodontal Ligament · Recombinant Proteins · Statistics, Nonparametric · Tetracyclines
[Abstract]

9 Matrix metalloproteinases-3, -8, -9 as markers of disease activity and joint damage progression in early rheumatoid arthritis
article 2003    
Author: Tchetverikov, I. · Lard, L.R. · Groot, J. de · Verzijl, N. · TeKoppele, J.M. · Breedveld, F.C. · Huizinga, T.W.J. · Hanemaaijer, R.
Keywords: Biology · Biomedical Research · gelatinase B · neutrophil collagenase · stromelysin · aged · arthropathy · disease activity · disease course · disease marker · enzyme activity · enzyme blood level · enzyme linked immunosorbent assay · female · human · joint destruction · longitudinal study · major clinical study · male · prediction · rheumatoid arthritis · Adult · alpha-Macroglobulins · Arthritis, Rheumatoid · Biological Markers · C-Reactive Protein · Disease Progression · Female · Humans · Joints · Male · Matrix Metalloproteinase 3 · Matrix Metalloproteinase 9 · Matrix Metalloproteinases · Middle Aged · Prospective Studies · Statistics, Nonparametric
[Abstract]

10 Matrix metalloproteinases in premature coronary atherosclerosis: influence of inhibitors, inflammation, and genetic polymorphisms
article 2007    
Author: Nanni, S. · Melandri, G. · Hanemaaijer, R. · Cervi, V. · Tomasi, L. · Altimari, A. · Lent, N. van · Tricoci, P. · Bacchi, L. · Branzi, A.
Keywords: Health · Biomedical Research · biological marker · gelatinase A · gelatinase B · glucose · haptoglobin · matrix metalloproteinase · stromelysin · tissue inhibitor of metalloproteinase · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · adult · article · controlled study · coronary artery atherosclerosis · correlation analysis · enzyme activity · enzyme blood level · exon · genetic polymorphism · glucose blood level · human · human tissue · inflammation · major clinical study · male · metabolic disorder · pathogenesis · priority journal · protein expression · protein localization
[Abstract]

11 Cathepsin K is the principal protease in giant cell tumor of bone
article 2004    
Author: Lindeman, J.H.N. · Hanemaaijer, R. · Mulder, A. · Dijkstra, P.D.S. · Szuhai, K. · Bromme, D. · Verheijen, J.H. · Hogendoorn, P.C.W.
Keywords: Health · Cathepsin K · Cathepsin L · Cathepsin S · Collagen · Collagenase 3 · Gelatinase B · Matrix metalloproteinase 14 · Messenger RNA · Proteinase · Bone tumor · Clinical article · Enzyme activity · Human tissue · Immunohistochemistry · Metaphysis · Osteolysis · Protein expression · Real time polymerase chain reaction · Adult · Bone Neoplasms · Cathepsins · Collagenases · Cysteine Endopeptidases · Female · Giant Cell Tumor of Bone · Humans · Immunoenzyme Techniques · Male · Matrix Metalloproteinase 13 · Matrix Metalloproteinases, Membrane-Associated · Metalloendopeptidases · Middle Aged · Osteoclasts · Osteolysis · RNA, Messenger
[Abstract]

12 Gingival tissue and crevicular fluid co-operation in adult periodontitis
article 2006    
Author: Beklen, A. · Tüter, G. · Sorsa, T. · Hanemaaijer, R. · Virtanen, I. · Tervahartiala, T. · Konttinen, Y.T.
Keywords: Health · Collagenase · Gelatinase · Periodontitis · Stromelysin · collagenase · enzyme precursor · gelatinase · gelatinase B · metalloproteinase · neutrophil collagenase · procollagenase · progelatinase · stromelysin · adult · article · cell culture · enzyme activation · enzymology · female · fibroblast · gingiva · gingivitis · human · immunohistochemistry · male · middle aged · pathology · periodontitis · Adult · Cells, Cultured · Collagenases · Enzyme Activation · Enzyme Precursors · Female · Fibroblasts · Gelatinases · Gingiva · Gingival Crevicular Fluid · Humans · Immunohistochemistry · Male · Matrix Metalloproteinase 3 · Matrix Metalloproteinase 8 · Matrix Metalloproteinase 9 · Metalloendopeptidases · Middle Aged · Periodontitis
[Abstract]

13 Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression
article 2014    
Author: Kim, E.S. · Cha, Y. · Ham, M. · Jung, J. · Kim, S.G. · Hwang, S. · Kleemann, R. · Moon, A.
Keywords: Biology · C-reactive protein · Invasion · MMP-9 · S1P · 2 (2 amino 3 methoxyphenyl)chromone · C reactive protein · CCAAT enhancer binding protein beta · Fingolimod · Gelatinase B · Mitogen activated protein kinase kinase · Reactive oxygen metabolite · Sphingosine 1 phosphate · Animal experiment · Animal model · Breast carcinoma · Breast cell · Cancer growth · Cell invasion · Controlled study · Enzyme activation · Epithelium cell · Female · Human · Human cell · In vitro study · In vivo study · Inflammation · Inflammatory breast cancer · Mouse · Nonhuman · Oncogene c fos · Phenotype · Priority journal · Protein expression · Transcription initiation · Tumor invasion · Upregulation · Xenograft · Mus · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

14 MMP profile in paired serum and synovial fluid samples of patients with rheumatoid arthritis
article 2004    
Author: Tchetverikov, I. · Ronday, H.K. · El, B. van · Kiers, G.H. · Verzijl, N. · TeKoppele, J.M. · Huizinga, T.W.J. · Groot, J. de · Hanemaaijer, R.
Keywords: alpha 2 macroglobulin · biological marker · gelatinase A · gelatinase B · hydroxyproline · interstitial collagenase · matrix metalloproteinase · neutrophil collagenase · stromelysin · tissue inhibitor of metalloproteinase 1 · aged · circulation · clinical article · collagen degradation · concentration (parameters) · controlled study · correlation analysis · enzyme activity · enzyme assay · enzyme linked immunosorbent assay · female · high performance liquid chromatography · human · male · osteoarthritis · priority journal · rheumatoid arthritis · sampling · serum · statistical significance · synovial fluid · Adult · Aged · alpha-Macroglobulins · Arthritis, Rheumatoid · Case-Control Studies · Collagenases · Enzyme Precursors · Enzyme-Linked Immunosorbent Assay · Female · Humans · Hydroxyproline · Male · Matrix Metalloproteinase 8 · Matrix Metalloproteinase 9 · Matrix Metalloproteinases · Metalloendopeptidases · Middle Aged · Osteoarthritis, Knee · Statistics, Nonparametric · Synovial Fluid · Tissue Inhibitor of Metalloproteinase-1
[Abstract]

15 Sirolimus and paclitaxel provoke different vascular pathological responses after local delivery in a murine model for restenosis on underlying atherosclerotic arteries
article 2007    
Author: Pires, N.M.M. · Eefting, D. · Vries, M.R.de · Quax, P.H.A. · Jukema, J.W.
Keywords: Biology · Biomedical Research · collagen · Fas antigen · gelatinase B · messenger RNA · paclitaxel · protein Bax · protein bcl 2 · rapamycin · tissue inhibitor of metalloproteinase 1 · animal experiment · animal model · animal tissue · apoptosis · article · atherosclerosis · blood vessel reactivity · cell disruption · controlled study · dose response · drug eluting stent · drug megadose · femoral artery · histopathology · hypercholesterolemia · male · mouse · nonhuman · priority journal · protein expression · real time polymerase chain reaction · restenosis · upregulation · Actins · Animals · Apoptosis · Atherosclerosis · Cell Proliferation · Collagen · Drug Implants · Femoral Artery · Image Interpretation, Computer-Assisted · In Situ Nick-End Labeling · Male · Mice · Mice, Mutant Strains · Models, Animal · Muscle, Smooth, Vascular · Paclitaxel · Recurrence · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger · Sirolimus · Stents · Tunica Intima
[Abstract]

16 Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis
article 2007    
Author: Fabriek, B.O. · Møller, H.J. · Vloet, R.P.M. · Winsen, L.M. van · Hanemaaijer, R. · Teunissen, C.E. · Uitdehaag, B.M.J. · Berg, T.K. van den · Dijkstra, C.D.
Keywords: Health · Biomedical Research · CD163 · Metalloproteinase · Monocytes · Multiple sclerosis · Scavenger receptor · sCD163 · CD163 antigen · cytokine · gelatinase B · scavenger receptor · adult · aged · analytic method · article · comparative study · controlled study · cytokine production · down regulation · enzyme activity · female · human · major clinical study · male · multiple sclerosis · priority journal · protein degradation · upregulation · Adolescent · Adult · Aged · Aged, 80 and over · Animals · Antigens, CD · Antigens, Differentiation, Myelomonocytic · Cell Line, Transformed · Cricetinae · Cricetulus · Cytokines · Enzyme Inhibitors · Enzyme-Linked Immunosorbent Assay · Female · Humans · Hydrocortisone · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Middle Aged · Multiple Sclerosis · Receptors, Cell Surface · Statistics, Nonparametric · Transfection
[Abstract]

17 Matrix metalloproteinase-2 is a consistent prognostic factor in gastric cancer
article 2006    
Author: Kubben, F.J.G.M. · Sier, C.F.M. · Duijn, W. van · Griffioen, G. · Hanemaaijer, R. · Velde, C.J.H. van de · Krieken, J.H.J.M. van · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Health · Biomedical Research · Gelatinases · MMP-7 · MMP-8 · MMP-9 · TIMP · Tissue inhibitor of metalloproteinases · gelatinase A · gelatinase B · matrilysin · neutrophil collagenase · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · bioassay · cancer classification · cancer patient · cancer staging · cancer survival · cancer tissue · comparative study · controlled study · correlation analysis · enzyme analysis · enzyme assay · enzyme linked immunosorbent assay · histopathology · human tissue · major clinical study · prognosis · protein variant · stomach cancer · stomach mucosa · tissue section · world health organization · Adult · Aged · Aged, 80 and over · Enzyme-Linked Immunosorbent Assay · Female · Humans · Male · Matrix Metalloproteinase 2 · Middle Aged · Predictive Value of Tests · Prognosis · Stomach Neoplasms · Survival Analysis
[PDF] [Abstract]

18 Pericellular proteases in angiogenesis and vasculogenesis
article 2006    
Author: Hinsbergh, V.W.M. van · Engelse, M.A. · Quax, P.H.A.
Keywords: Biology · Biomedical Research · Cathepsins · Endothelium · MT-MMPs · Neovascularization · Aminopeptidase · Angiogenic factor · Cathepsin L · Cytokine · Gelatinase A · Gelatinase B · Hemostatic agent · Hermes antigen · Matrix metalloproteinase 14 · Matrix metalloproteinase inhibitor · Pericellular proteinase · Proteinase · Serine proteinase · Unclassified drug · Urokinase · Vitronectin receptor · Accessory cell · Angiogenesis · Antiangiogenic activity · Antigen binding · Blood cell · Bone marrow cell · Cell membrane · Cell migration · Cell survival · Endothelium cell · Enzyme activity · Enzyme localization · Enzyme substrate complex · Extracellular matrix · Focal adhesion · Lamellipodium · Nonhuman · Protein degradation · Receptor binding · Vascular endothelium · ADAM Proteins · Aminopeptidases · Animals · Bone Marrow Cells · Cathepsins · Cell Differentiation · Cell Movement · Extracellular Matrix · Extracellular Matrix Proteins · Humans · Matrix Metalloproteinases · Mice · Neovascularization, Pathologic · Neovascularization, Physiologic · Peptide Hydrolases · Pericytes · Serine Endopeptidases · Tissue Inhibitor of Metalloproteinases
[Abstract]

19 Doxycycline therapy for abdominal aneurysm: Improved proteolytic balance through reduced neutrophil content
article 2009    
Author: Abdul-Hussien, H. · Hanemaaijer, R. · Verheijen, J.H. · Bockel, J.H. van · Geelkerken, R.H. · Lindeman, J.H.N.
Keywords: Biology · Biomedical Research · antihypertensive agent · antithrombocytic agent · cystatin C · cysteine proteinase · doxycycline · gelatinase B · hydroxymethylglutaryl coenzyme A reductase inhibitor · messenger RNA · neutrophil collagenase · stromelysin · tissue inhibitor of metalloproteinase 1 · abdominal aorta aneurysm · adult · aged · aorta wall · article · clinical article · clinical trial · controlled clinical trial · controlled study · dose response · drug effect · drug megadose · drug tolerability · enzyme activity · enzyme assay · female · gene expression · human · human tissue · immunohistochemistry · low drug dose · male · neutrophil · polymerase chain reaction · priority journal · protein degradation · quantitative analysis · randomized controlled trial · treatment duration · Western blotting · Aged · Aged, 80 and over · Aorta, Abdominal · Aortic Aneurysm, Abdominal · Cardiovascular Agents · Cystatin C · Cysteine Endopeptidases · Dose-Response Relationship, Drug · Doxycycline · Female · Gene Expression Regulation, Enzymologic · Humans · Male · Matrix Metalloproteinases · Middle Aged · Neutrophil Infiltration · Neutrophils · Prospective Studies · Protease Inhibitors · RNA, Messenger · Time Factors · Tissue Inhibitor of Metalloproteinase-1 · Treatment Outcome · Vascular Surgical Procedures
[Abstract]

20 Effect of the anti-tumor necrosis factor-α antibody infliximab on the ex vivo mucosal matrix metalloproteinase-proteolytic phenotype in inflammatory bowel disease
article 2007    
Author: Meijer, M.J. · Mieremet-Ooms, M.A.C. · Duijn, W. van · Zon, A.M. van der · Hanemaaijer, R. · Verheijen, J.H. · Hogezand, R.A. van · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biomedical Research · Inflammatory bowel disease · Infliximab · Matrix metalloproteinase · Tissue inhibitor of metalloproteinase · Tumor necrosis factor-alpha · azathioprine · cyclosporin · gelatinase A · gelatinase B · infliximab · interstitial collagenase · mesalazine · messenger RNA · pokeweed mitogen · steroid · stromelysin · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · tumor necrosis factor alpha antibody · adolescent · adult · aged · article · clinical article · controlled study · Crohn disease · drug effect · enteritis · explant · female · genotype · human · human tissue · intestine mucosa · male · priority journal · protein degradation · protein expression · single nucleotide polymorphism · ulcerative colitis · Adolescent · Adult · Aged · Antibodies, Monoclonal · Colitis, Ulcerative · Crohn Disease · Down-Regulation · Female · Humans · Intestinal Mucosa · Male · Matrix Metalloproteinases · Middle Aged · Phenotype · Polymorphism, Single Nucleotide · Reverse Transcriptase Polymerase Chain Reaction · Tissue Culture Techniques · Tissue Inhibitor of Metalloproteinases · Tumor Necrosis Factor-alpha
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 21 found. Next | Sort by date